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Images
Published: 01 August 2023
SMALL CELL CARCINOMA OF NEUROENDOCRINE TYPE Figure 7-29 SMALL CELL CARCINOMA OF NEUROENDOCRINE TYPE Unlike undifferentiated carcinoma, this tumor shows nuclear molding, neuroendocrine-type chromatin and conspicuous apoptosis. More about this image found in SMALL CELL CARCINOMA OF NEUROENDOCRINE TYPE Unlike undifferentiated carcin...
Images
Published: 01 August 2023
GOBLET CELL ADENOCARCINOMA METASTATIC TO THE OVARY Figure 15-4 GOBLET CELL ADENOCARCINOMA METASTATIC TO THE OVARY Left: At low power, the tumor resembles a signet ring cell carcinoma. Right: At high power, neuroendocrine granules are seen (arrowheads). More about this image found in GOBLET CELL ADENOCARCINOMA METASTATIC TO THE OVARY Left: At low power, the...
Images
Published: 01 August 2023
EPENDYMOMA OF BROAD LIGAMENT Figure 16-39 EPENDYMOMA OF BROAD LIGAMENT The low-power appearance sometimes recalls a neuroendocrine tumor (A) or an endometrioid neoplasm (B), but the presence of ependymal pseudorosettes (C) should raise the possibility of ependymoma. This diagnostic impression can... More about this image found in EPENDYMOMA OF BROAD LIGAMENT The low-power appearance sometimes recalls a ...
Images
Published: 01 August 2023
CARCINOMA METASTATIC TO FALLOPIAN TUBE Figure 16-30 CARCINOMA METASTATIC TO FALLOPIAN TUBE A: Lobular carcinoma of breast. B: Colorectal adenocarcinoma with an intraepithelial and invasive profile. C: Signet ring cell carcinoma of stomach. D: Well-differentiated neuroendocrine carcinoma (carci... More about this image found in CARCINOMA METASTATIC TO FALLOPIAN TUBE A: Lobular carcinoma of breast. B:...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 16
Published: 01 August 2023
10.55418/9781933477282-07
ISBN-10: 1-933477-28-8
ISBN: 978-1-933477-28-2
... WITH A COMPONENT OF GIANT CELL CARCINOMA Figure 7-28 ENDOMETRIOID CARCINOMA WITH A COMPONENT OF GIANT CELL CARCINOMA Conventional endometrioid differentiation is present at left, while undifferentiated giant cells predominate on the right. SMALL CELL CARCINOMA OF NEUROENDOCRINE TYPE Figure 7-29 SMALL CELL...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 16
Published: 01 August 2023
10.55418/9781933477282-14
ISBN-10: 1-933477-28-8
ISBN: 978-1-933477-28-2
... in dedifferentiated carcinomas. Molecular analysis of SCCOHT shows mutations in the SMARCA4 gene, and a lack of the endometrioid-type mutations that are characteristically seen in un- and dedifferentiated carcinomas. Small Cell Neuroendocrine Carcinoma (SCNEC). These are high grade neuroendocrine tumors...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 16
Published: 01 August 2023
10.55418/9781933477282-13
ISBN-10: 1-933477-28-8
ISBN: 978-1-933477-28-2
.... Mixed germ cell tumors are heterogenous, often with a lobulated appearance. Hemorrhage and necrosis can be seen ( fig. 13-16 ). Extensive sampling is necessary to identify all the components. Definition. Carcinoid tumors are indistinguishable from low-grade neuroendocrine tumor...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 16
Published: 01 August 2023
10.55418/9781933477282-03
ISBN-10: 1-933477-28-8
ISBN: 978-1-933477-28-2
... carcinoma, pancreatic neuroendocrine tumor, pheochromocytoma, paraganglioma, and as for the gynecologic tract, papillary cystadenoma, usually found in the broad ligament. Most patients come to clinical attention between 18 and 30 years of age (average, 26 years of age), with a range from 5 to 65 years ( 43...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 16
Published: 01 August 2023
10.55418/9781933477282-16
ISBN-10: 1-933477-28-8
ISBN: 978-1-933477-28-2
... fallopian primary from metastasis to the fallopian tube when the lesion has an intraepithelial distribution (right). EPENDYMOMA OF BROAD LIGAMENT Figure 16-39 EPENDYMOMA OF BROAD LIGAMENT The low-power appearance sometimes recalls a neuroendocrine tumor (A) or an endometrioid neoplasm (B...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 16
Published: 01 August 2023
10.55418/9781933477282-15
ISBN-10: 1-933477-28-8
ISBN: 978-1-933477-28-2
... 15-4 GOBLET CELL ADENOCARCINOMA METASTATIC TO THE OVARY Left: At low power, the tumor resembles a signet ring cell carcinoma. Right: At high power, neuroendocrine granules are seen (arrowheads). METASTATIC SIGNET RING-TYPE GASTRIC CANCER (“KRUKENBERG TUMOR”) Figure 15-3 METASTATIC SIGNET RING...
Book Chapter
Book: Tumors of the Pancreas
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 15
Published: 01 March 2023
10.55418/9781933477275-12
ISBN-10: 1-933477-27-X
ISBN: 978-1-933477-27-5
...Table 12-1 WORLD HEALTH ORGANIZATION (WHO) CLASSIFICATION OF PANCREATIC NEUROENDOCRINE NEOPLASMS a Differentiation Terminology Mitoses per 2 mm2 Ki-67 Index b Well differentiated NET c G1 <2 <3% NET G2 2 - 20 3 - 20% NET...
Images
Published: 01 March 2023
MIXED DUCTAL-NEUROENDOCRINE CARCINOMA Figure 12-87 MIXED DUCTAL-NEUROENDOCRINE CARCINOMA Left: The neuroendocrine component is poorly differentiated, large cell type, and the adenocarcinoma component resembles conventional ductal adenocarcinoma, with simple mucinous glands. Right: Mucicarmine st... More about this image found in MIXED DUCTAL-NEUROENDOCRINE CARCINOMA Left: The neuroendocrine component i...
Images
Published: 01 March 2023
MIXED ACINAR-NEUROENDOCRINE CARCINOMA Figure 9-45 MIXED ACINAR-NEUROENDOCRINE CARCINOMA Smears of mixed acinar neuroendocrine carcinomas are highly cellular, similar to pure acinar cell carcinomas. Atypical plasmacytoid cells with granular cytoplasm appear singly dispersed (Diff Quik). More about this image found in MIXED ACINAR-NEUROENDOCRINE CARCINOMA Smears of mixed acinar neuroendocrin...
Images
Published: 01 March 2023
MIXED SEROUS-NEUROENDOCRINE NEOPLASM ASSOCIATED WITH VHL DISEASE Figure 4-11 MIXED SEROUS-NEUROENDOCRINE NEOPLASM ASSOCIATED WITH VHL DISEASE Left: Solid, nodular, yellow-white neuroendocrine tumor is adjacent to microcystic serous cystadenoma. Right: At higher power, the neuroendocrine and sero... More about this image found in MIXED SEROUS-NEUROENDOCRINE NEOPLASM ASSOCIATED WITH VHL DISEASE Left: Sol...
Images
Published: 01 March 2023
VHL-ASSOCIATED SEROUS CYSTADENOMA AND NEUROENDOCRINE TUMOR Figure 4-19 VHL-ASSOCIATED SEROUS CYSTADENOMA AND NEUROENDOCRINE TUMOR Both small serous neoplasms (A, top) and a neuroendocrine tumor (A, bottom) are present in this patient with VHL. The serous neoplasms are microcystic (B) and some are... More about this image found in VHL-ASSOCIATED SEROUS CYSTADENOMA AND NEUROENDOCRINE TUMOR Both small sero...
Images
Published: 01 March 2023
VHL-ASSOCIATED MIXED SEROUS-NEUROENDOCRINE NEOPLASM Figure 4-20 VHL-ASSOCIATED MIXED SEROUS-NEUROENDOCRINE NEOPLASM Low-power (left) and close-up view (right) demonstrate neuroendocrine tumor components adjacent to microcysts lined by flattened cuboidal cells. The neuroendocrine neoplasm has foca... More about this image found in VHL-ASSOCIATED MIXED SEROUS-NEUROENDOCRINE NEOPLASM Low-power (left) and c...
Images
Published: 01 March 2023
INTRADUCTAL PAPILLARY MUCINOUS NEOPLASM Figure 6-35 INTRADUCTAL PAPILLARY MUCINOUS NEOPLASM The neuroendocrine cells immuno label for chromogranin A. More about this image found in INTRADUCTAL PAPILLARY MUCINOUS NEOPLASM The neuroendocrine cells immuno la...
Images
Published: 01 March 2023
MIXED ACINAR-NEUROENDOCRINE CARCINOMA Figure 9-38 MIXED ACINAR-NEUROENDOCRINE CARCINOMA The neoplasm is solid and fleshy, with minimal fibrous stroma, similar to acinar cell carcinomas. More about this image found in MIXED ACINAR-NEUROENDOCRINE CARCINOMA The neoplasm is solid and fleshy, wi...
Images
Published: 01 March 2023
MIXED ACINAR-NEUROENDOCRINE CARCINOMA Figure 9-39 MIXED ACINAR-NEUROENDOCRINE CARCINOMA This case has separate, morphologically recognizable com ponents, with the acinar elements comprising the central portion (top, and upper inset) and the neuroendocrine elements lining the periphery, beneath th... More about this image found in MIXED ACINAR-NEUROENDOCRINE CARCINOMA This case has separate, morphologica...
Images
Published: 01 March 2023
MIXED ACINAR-NEUROENDOCRINE CARCINOMA Figure 9-40 MIXED ACINAR-NEUROENDOCRINE CARCINOMA Immunolabeling for trypsin (A) and chromogranin (B) identifies the two components in the case from figure 9-39 . By double immunolabeling (C), the central acinar cells (blue reaction product) are sharply dist... More about this image found in MIXED ACINAR-NEUROENDOCRINE CARCINOMA Immunolabeling for trypsin (A) and c...
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