CYSTIC NEPHROMA Figure 2-264 CYSTIC NEPHROMA Cystic nephroma is simple and consists of cysts lined by a single layer of epithelium. The cysts are separated by septa, which most often are hypocellular and fibrous. More about this image found in CYSTIC NEPHROMA Cystic nephroma is simple and consists of cysts lined by a...

CONGENITAL MESOBLASTIC NEPHROMA, CELLULAR TYPE, MIMICKING RHABDOID TUMOR Figure 1-114 CONGENITAL MESOBLASTIC NEPHROMA, CELLULAR TYPE, MIMICKING RHABDOID TUMOR Left: Some of this neoplasm has the poorly formed fascicles of spindle cells with hyperchromatic pointed nuclei typical of cellular congenital mesoblastic nephroma. Right: Other areas, however, demonstrate sheets of epithelioid cells with nuclei having vesicular chromatin and prominent nucleoli that suggest the diagnosis of rhabdoid tumor. This neoplasm demonstrated the ETV6-NTRK3 gene fusion of cellular congenital mesoblastic nephroma, and the patient was free of disease at 7 years follow-up following nephrectomy without adjuvant therapy. More about this image found in CONGENITAL MESOBLASTIC NEPHROMA, CELLULAR TYPE, MIMICKING RHABDOID TUMOR L...

CONGENITAL MESOBLASTIC NEPHROMA Figure 1-60 CONGENITAL MESOBLASTIC NEPHROMA Age distribution curve for patients with congenital mesoblastic nephroma based on cases at the National Wilms Tumor Study Group Pathology Center. More about this image found in CONGENITAL MESOBLASTIC NEPHROMA Age distribution curve for patients with c...

CONGENITAL MESOBLASTIC NEPHROMA, CLASSIC TYPE Figure 1-69 CONGENITAL MESOBLASTIC NEPHROMA, CLASSIC TYPE When classic congenital mesoblastic nephroma penetrates through the renal capsule, it typically induces a prominent angiomatous capillary vascular proliferation. More about this image found in CONGENITAL MESOBLASTIC NEPHROMA, CLASSIC TYPE When classic congenital meso...

CYSTIC NEPHROMA Figure 2-269 CYSTIC NEPHROMA Foci of dense collagen deposition are sometime seen. To some eyes, these resemble ovarian corpora albicantia. Of course, they have nothing to do with the ovary and are perivascular sclerosis which is not specific to cystic nephroma. More about this image found in CYSTIC NEPHROMA Foci of dense collagen deposition are sometime seen. To so...

SEGMENTAL POLYCYSTIC KIDNEY DISEASE MIMICKING PEDIATRIC CYSTIC NEPHROMA Figure 1-119 SEGMENTAL POLYCYSTIC KIDNEY DISEASE MIMICKING PEDIATRIC CYSTIC NEPHROMA This solitary lesion was entirely cystic, but unlike cystic nephroma it permeates between native tubules (left) and lacks a characteristic l... More about this image found in SEGMENTAL POLYCYSTIC KIDNEY DISEASE MIMICKING PEDIATRIC CYSTIC NEPHROMA Th...

CYSTIC NEPHROMA Figure 2-267 CYSTIC NEPHROMA In smaller and presumably younger cystic nephromas, the stroma in the septa may be more cellular and the spindle cells may have a “wavy” appearance, reminiscent of ovarian stroma. Microscopic cysts resembling cross sections of renal tubules are commonl... More about this image found in CYSTIC NEPHROMA In smaller and presumably younger cystic nephromas, the st...

CONGENITAL MESOBLASTIC NEPHROMA, MIXED TYPE Figure 1-75 CONGENITAL MESOBLASTIC NEPHROMA, MIXED TYPE Left: In the mixed pattern, areas morphologically identical to the cellular type (left) abut less cellular, more fascicular areas identical to the classic type (right). Right: In mixed pattern con... More about this image found in CONGENITAL MESOBLASTIC NEPHROMA, MIXED TYPE Left: In the mixed pattern, ar...

CONGENITAL MESOBLASTIC NEPHROMA, CELLULAR TYPE Figure 1-71 CONGENITAL MESOBLASTIC NEPHROMA, CELLULAR TYPE A: This cellular neoplasm is well delineated from the kidney at the top. B: Cellular congenital mesoblastic nephroma is typically composed of monomorphic plump spindle cells, often with no d... More about this image found in CONGENITAL MESOBLASTIC NEPHROMA, CELLULAR TYPE A: This cellular neoplasm i...

CYSTIC NEPHROMA Figure 2-270 CYSTIC NEPHROMA Left: In the cellular stroma a positive reaction for inhibin is seen in some of the spindle cells, a reaction not found in other cystic renal tumors. Right: The cellular stroma also frequently shows a positive reaction for progesterone receptor and le... More about this image found in CYSTIC NEPHROMA Left: In the cellular stroma a positive reaction for inhib...

CYSTIC NEPHROMA Figure 2-263 CYSTIC NEPHROMA The tumor has herniated into the cavity of the renal pelvis. More about this image found in CYSTIC NEPHROMA The tumor has herniated into the cavity of the renal pelvi...

PEDIATRIC CYSTIC NEPHROMA Figure 1-116 PEDIATRIC CYSTIC NEPHROMA Expansive solid nodules are absent in this CT image. More about this image found in PEDIATRIC CYSTIC NEPHROMA Expansive solid nodules are absent in this CT im...

CYSTIC NEPHROMA Figure 2-266 CYSTIC NEPHROMA The stroma in the septa is often collagenous. A sprinkling of lymphocytes sometimes is present. More about this image found in CYSTIC NEPHROMA The stroma in the septa is often collagenous. A sprinkling...

CONGENITAL MESOBLASTIC NEPHROMA, CLASSIC TYPE Figure 1-68 CONGENITAL MESOBLASTIC NEPHROMA, CLASSIC TYPE Extramedullary hematopoiesis is common within these neoplasms. More about this image found in CONGENITAL MESOBLASTIC NEPHROMA, CLASSIC TYPE Extramedullary hematopoiesis...

CONGENITAL MESOBLASTIC NEPHROMA, CLASSIC TYPE Figure 1-67 CONGENITAL MESOBLASTIC NEPHROMA, CLASSIC TYPE An island of cartilage in the neoplasm represents renal dysplasia. More about this image found in CONGENITAL MESOBLASTIC NEPHROMA, CLASSIC TYPE An island of cartilage in th...

CONGENITAL MESOBLASTIC NEPHROMA Figure 1-76 CONGENITAL MESOBLASTIC NEPHROMA Electron micrograph demonstrates prominent rough endoplasmic reticulum typical of fibroblastic cells. More about this image found in CONGENITAL MESOBLASTIC NEPHROMA Electron micrograph demonstrates prominent...

CONGENITAL MESOBLATIC NEPHROMA, CLASSIC TYPE Figure 1-62 CONGENITAL MESOBLATIC NEPHROMA, CLASSIC TYPE The lesion is fibrous and ill-defined, permeating the native kidney. More about this image found in CONGENITAL MESOBLATIC NEPHROMA, CLASSIC TYPE The lesion is fibrous and ill...

PEDIATRIC CYSTIC NEPHROMA: ESTROGEN RECEPTOR Figure 1-118 PEDIATRIC CYSTIC NEPHROMA: ESTROGEN RECEPTOR There is typically prominent nuclear labeling in the looser fibrous stroma. More about this image found in PEDIATRIC CYSTIC NEPHROMA: ESTROGEN RECEPTOR There is typically prominent ...

CONGENITAL MESOBLASTIC NEPHROMA, CELLULAR TYPE Figure 1-77 CONGENITAL MESOBLASTIC NEPHROMA, CELLULAR TYPE This is a rare liver metastasis. Benign bile ducts are seen at the top. More about this image found in CONGENITAL MESOBLASTIC NEPHROMA, CELLULAR TYPE This is a rare liver metast...