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nephroblastoma

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Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 16
Published: 01 August 2023
10.55418/9781933477282-14
ISBN-10: 1-933477-28-8
ISBN: 978-1-933477-28-2
... : 18 - 21 . 46. Isaac   MA , Vijayalakshmi   S , Madhu   CS , Bosincu   L , Nogales   FF . Pure cystic nephroblastoma of the ovary with a review of extrarenal Wilms’ tumors . Hum Pathol   2000 ; 31 : 761 - 4 . 47. Agopiantz   M , Journeau   P , Lebon-Labich   B...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 15
Published: 01 March 2023
10.55418/9781933477275-10
ISBN-10: 1-933477-27-X
ISBN: 978-1-933477-27-5
... study first demonstrated acinar differentiation in pancreatoblastoma. The proposal of the term pancreatoblastoma was intended to reflect the primitive nature of the neoplasm, analogous to hepatoblastoma or nephroblastoma. Palosaari et al. ( 5 ) first reported a pancreatoblastoma arising in an adult...
Images
<span class="search-highlight">NEPHROBLASTOMA</span> IN POSTPUBERTAL-TYPE TERATOMA  Occasionally, the neoplastic ...
Published: 01 August 2022
NEPHROBLASTOMA IN POSTPUBERTAL-TYPE TERATOMA Figure 4-189 NEPHROBLASTOMA IN POSTPUBERTAL-TYPE TERATOMA Occasionally, the neoplastic stroma and background fibrous tissue separate the epithelial and blastema elements into nodular aggregates. More about this image found in NEPHROBLASTOMA IN POSTPUBERTAL-TYPE TERATOMA Occasionally, the neoplastic ...
Images
<span class="search-highlight">NEPHROBLASTOMA</span> IN POSTPUBERTAL-TYPE TERATOMA  A: There is a triphasic proli...
Published: 01 August 2022
NEPHROBLASTOMA IN POSTPUBERTAL-TYPE TERATOMA Figure 4-188 NEPHROBLASTOMA IN POSTPUBERTAL-TYPE TERATOMA A: There is a triphasic proliferation of primitive tubules, blastema, and stroma. B: WT1 reactivity is patchy in the same case as shown in A. C: The primitive renal tubules sometimes form glom... More about this image found in NEPHROBLASTOMA IN POSTPUBERTAL-TYPE TERATOMA A: There is a triphasic proli...
Images
POSTCHEMOTHERAPY <span class="search-highlight">NEPHROBLASTOMA</span>  Left: A lobular proliferation of primitive...
Published: 01 August 2022
POSTCHEMOTHERAPY NEPHROBLASTOMA Figure 4-236 POSTCHEMOTHERAPY NEPHROBLASTOMA Left: A lobular proliferation of primitive tubules, blastema, and stroma occupies a large area. Several glomeruloid structures are apparent. Right: Higher power shows mostly tubules and a glomerulus-like body with scant... More about this image found in POSTCHEMOTHERAPY NEPHROBLASTOMA Left: A lobular proliferation of primitive...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 13
Published: 01 November 2022
10.55418/9781933477251-2
ISBN-10: 1-933477-25-3
ISBN: 978-1-933477-25-1
... neuroendocrine carcinomas from a variety of sites may be positive for TTF1. TTF1 also stains tumors of the ovary, breast, colon, kidney (nephroblastomas), and brain (gliomas), and thus it is not a highly specific marker ( 52 , 56 – 62 ). Differing clones of TTF1 vary in sensitivity and specificity: for example...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 13
Published: 01 November 2022
10.55418/9781933477251-5
ISBN-10: 1-933477-25-3
ISBN: 978-1-933477-25-1
..., nephroblastoma, melanoma, small cell mesothelioma ( 90 , 94 ), and medullary thyroid carcinoma, but it is also immunoreactive with folliculogenic (papillary and follicular) thyroid tumors ( 95 ). Protein Gene Product 9.5 (PGP9.5) Protein gene product 9.5/ubiquitin c-terminal hydrolase-L1 (PGP9.5/UCHL1...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 12
Published: 01 August 2022
10.55418/9781933477220-04
ISBN-10: 1-933477-22-9
ISBN: 978-1-933477-22-0
... neoplasia in situ; Sem = seminoma; EC = embryonal carcinoma; YST = yolk sac tumor; PSTT = placental site trophoblastic tumor; ETT = epithelioid trophoblastic tumor; CTT = cystic trophoblastic tumor; Ter = teratoma; ENT = embryonic-type neuroectodermal tumor; NBT = nephroblastoma; ST = spermatocytic tumor...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 12
Published: 01 August 2022
10.55418/9781933477220-03
ISBN-10: 1-933477-22-9
ISBN: 978-1-933477-22-0
... mesothelioma/tumor  Desmoplastic round cell tumor  Melanotic neuroectodermal tumor  Paraganglioma  Nephroblastoma Tumors of the Collecting Ducts and Rete Testis  Adenoma   Sertoliform cystadenoma  Adenocarcinoma/sarcomatoid carcinoma/carcino sarcoma Epithelial Tumors...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 12
Published: 01 August 2022
10.55418/9781933477220-08
ISBN-10: 1-933477-22-9
ISBN: 978-1-933477-22-0
.... The standard treatment is surgical excision with follow-up. Those patients with germline mutations require appropriate genetic counseling and monitoring for neoplasms at other sites associated with the known mutation. NEPHROBLASTOMA Nephroblastoma, apart from those that originate from a germ cell...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 12
Published: 01 August 2022
10.55418/9781933477220-05
ISBN-10: 1-933477-22-9
ISBN: 978-1-933477-22-0
... qualified for grade 1 by this approach. In addition to neuroectoderm, any embryonic-type tissue should be considered sufficient for classification as immature; in our experience, this has only consisted of primitive tubules and blastema resembling foci of nephroblastoma. Fetal-type tissue, while nominally...
Images
MINIMAL NODAL INVOLVEMENT BY BLASTEMAL <span class="search-highlight">NEPHROBLASTOMA</span>  Left: Small clusters...
Published: 01 November 2021
MINIMAL NODAL INVOLVEMENT BY BLASTEMAL NEPHROBLASTOMA Figure 1-130 MINIMAL NODAL INVOLVEMENT BY BLASTEMAL NEPHROBLASTOMA Left: Small clusters of blastemal cells in the lymph node sinus (arrow) can be difficult to distinguish from displaced germinal centers or other lymphocytes (left). Their cohes... More about this image found in MINIMAL NODAL INVOLVEMENT BY BLASTEMAL NEPHROBLASTOMA Left: Small clusters...
Images
<span class="search-highlight">NEPHROBLASTOMA</span>  The early primitive tubules of <span class="search-highlight">nephroblastoma</span> lack lumens, ...
Published: 01 November 2021
NEPHROBLASTOMA Figure 1-14 NEPHROBLASTOMA The early primitive tubules of nephroblastoma lack lumens, and invite confusion with Homer-Wright rosettes. Areas with true tubular lumens (upper left and right) are focally present. More about this image found in NEPHROBLASTOMA The early primitive tubules of nephroblastoma lack lumens, ...
Images
<span class="search-highlight">NEPHROBLASTOMA</span>  Highly differentiated skeletal muscle in <span class="search-highlight">nephroblastoma</span> can...
Published: 01 November 2021
NEPHROBLASTOMA Figure 1-20 NEPHROBLASTOMA Highly differentiated skeletal muscle in nephroblastoma can resemble fetal rhabdomyoma. This morphologic pattern has no clinical significance. More about this image found in NEPHROBLASTOMA Highly differentiated skeletal muscle in nephroblastoma can...
Images
WT1 EXPRESSION IN <span class="search-highlight">NEPHROBLASTOMA</span>  In a triphasic <span class="search-highlight">nephroblastoma</span> (left), nuc...
Published: 01 November 2021
WT1 EXPRESSION IN NEPHROBLASTOMA Figure 1-28 WT1 EXPRESSION IN NEPHROBLASTOMA In a triphasic nephroblastoma (left), nuclear labeling for WT1 is typically most prominent in primitive blastemal and epithelial components, while more differentiated epithelium and stroma are negative (right). More about this image found in WT1 EXPRESSION IN NEPHROBLASTOMA In a triphasic nephroblastoma (left), nuc...
Images
<span class="search-highlight">NEPHROBLASTOMA</span>  Occasionally, an otherwise typical <span class="search-highlight">nephroblastoma</span> (A,B) wit...
Published: 01 November 2021
NEPHROBLASTOMA Figure 1-32 NEPHROBLASTOMA Occasionally, an otherwise typical nephroblastoma (A,B) with abundant mitotic activity may have differentiated epithelial areas within it (C) that mimic metanephric adenoma. More about this image found in NEPHROBLASTOMA Occasionally, an otherwise typical nephroblastoma (A,B) wit...
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<span class="search-highlight">NEPHROBLASTOMA</span> ARISING IN PERILOBAR NEPHROGENIC RESTS  The <span class="search-highlight">nephroblastoma</span> i...
Published: 01 November 2021
NEPHROBLASTOMA ARISING IN PERILOBAR NEPHROGENIC RESTS Figure 1-44 NEPHROBLASTOMA ARISING IN PERILOBAR NEPHROGENIC RESTS The nephroblastoma is spherical and delineated from the perilobar rest from which it arose by a thin fibrous capsule. More about this image found in NEPHROBLASTOMA ARISING IN PERILOBAR NEPHROGENIC RESTS The nephroblastoma i...
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BLASTEMAL <span class="search-highlight">NEPHROBLASTOMA</span> VERSUS LYMPHOCYTES  Blastemal <span class="search-highlight">nephroblastoma</span> cells...
Published: 01 November 2021
BLASTEMAL NEPHROBLASTOMA VERSUS LYMPHOCYTES Figure 1-131 BLASTEMAL NEPHROBLASTOMA VERSUS LYMPHOCYTES Blastemal nephroblastoma cells (left) have finer chromatin and demonstrate more nuclear molding than lymphocytes (right). More about this image found in BLASTEMAL NEPHROBLASTOMA VERSUS LYMPHOCYTES Blastemal nephroblastoma cells...
Images
<span class="search-highlight">NEPHROBLASTOMA</span> MIMICKING CLEAR CELL SARCOMA OF THE KIDNEY  Left: Blastemal ...
Published: 01 November 2021
NEPHROBLASTOMA MIMICKING CLEAR CELL SARCOMA OF THE KIDNEY Figure 1-95 NEPHROBLASTOMA MIMICKING CLEAR CELL SARCOMA OF THE KIDNEY Left: Blastemal areas of nephroblastoma may have the same branching capillary vasculature as clear cell sarcoma of the kidney, and underfixed nuclei may show bubbling wh... More about this image found in NEPHROBLASTOMA MIMICKING CLEAR CELL SARCOMA OF THE KIDNEY Left: Blastemal ...
Images
<span class="search-highlight">NEPHROBLASTOMA</span> ARISING IN INTRALOBAR NEPHROGENIC RESTS  Left: The nephrobla...
Published: 01 November 2021
NEPHROBLASTOMA ARISING IN INTRALOBAR NEPHROGENIC RESTS Figure 1-53 NEPHROBLASTOMA ARISING IN INTRALOBAR NEPHROGENIC RESTS Left: The nephroblastoma on the right of figure is solid and well delineated by a thin fibrous capsule. The intralobar nephrogenic rest on the left of the figure contains fat ... More about this image found in NEPHROBLASTOMA ARISING IN INTRALOBAR NEPHROGENIC RESTS Left: The nephrobla...