Search Results for neoplastic

SCHWANNOMA Figure 1-85 SCHWANNOMA The neoplastic cells show a strong nuclear and cytoplasmic S-100 protein reaction (A) and SOX10 nuclear reaction (B). More about this image found in SCHWANNOMA The neoplastic cells show a strong nuclear and cytoplasmic S-10...

NEUROFIBROMA Figure 1-89 NEUROFIBROMA A,B: Some of the neoplastic cells are strongly S-100 protein reactive (A), with a similar population reacting with SOX10 (B). C: CD34 highlights numerous fibroblasts in this neurofibroma. D: Calretinin only highlights rare, isolated neurofibroma cells. More about this image found in NEUROFIBROMA A,B: Some of the neoplastic cells are strongly S-100 protein ...

GLOMANGIOPERICYTOMA Figure 1-103 GLOMANGIOPERICYTOMA A: Hemorrhage partially obscures the neoplastic proliferation. B: Extravasated erythrocytes are noted between the neoplastic cells. C: Eosinophils and mast cells are present, although sometimes difficult to see. D: Eosinophils and mast More about this image found in GLOMANGIOPERICYTOMA A: Hemorrhage partially obscures the neoplastic prolif...

DESMOID-TYPE FIBROMATOSIS Figure 1-109 DESMOID-TYPE FIBROMATOSIS A,B: The neoplastic cells are elongated and spindled, separated by a collagenized stroma. The cellularity varies from hypercellular (A) to hypocellular (B). C: The vessels may be thin and collapsed. D: The neoplastic cells More about this image found in DESMOID-TYPE FIBROMATOSIS A,B: The neoplastic cells are elongated and spin...

OLFACTORY NEUROBLASTOMA Figure 1-135 OLFACTORY NEUROBLASTOMA A–C: The neoplastic cells of ONB are generally small (A), with scant to lightly staining cytoplasm (B), occasionally showing spindling or irregular outlines (C). D: An “in situ” or intraepithelial growth may be seen (black arrow More about this image found in OLFACTORY NEUROBLASTOMA A–C: The neoplastic cells of ONB are generally sma...

MUCOSAL MELANOMA Figure 1-151 MUCOSAL MELANOMA A: Histiocytes are seen, along with pigmented neoplastic cells (prominent nucleoli). B: Pigmentation is noted within the minor mucoserous glands, as well as in the histiocytes and neoplastic cells. C: This spindled melanoma shows prominent melanin More about this image found in MUCOSAL MELANOMA A: Histiocytes are seen, along with pigmented neoplastic ...

MUCOSAL MELANOMA Figure 1-155 MUCOSAL MELANOMA No matter the pattern or the cytology, the neoplastic cells show variable reactivity with a number of melanocytic markers. A: Spindled cells with S-100 protein nuclear and cytoplasmic reactivity. B: Strong, diffuse, nuclear reaction with SOX10. C More about this image found in MUCOSAL MELANOMA No matter the pattern or the cytology, the neoplastic cel...

MENINGIOMA Figure 1-159 MENINGIOMA A: A polyp has an intact epithelium with a lobular neoplastic proliferation in the stroma. B: The epithelium is intact, overlying a meningothelial proliferation. C: The neoplastic cells invade around the minor mucoserous glands (white arrow), and blend More about this image found in MENINGIOMA A: A polyp has an intact epithelium with a lobular neoplastic p...

MENINGIOMA Figure 1-162 MENINGIOMA A: The neoplastic cells show weak to strong, patchy cytoplasmic reactivity with epithelial membrane antigen (EMA). B: The native epithelium and minor mucoserous glands are reactive with CK7, while the meningioma is negative. More about this image found in MENINGIOMA A: The neoplastic cells show weak to strong, patchy cytoplasmic...

NK/T-CELL LYMPHOMA Figure 1-181 NK/T-CELL LYMPHOMA A,B: The neoplastic lymphoma cells show an NK-cell phenotype with CD56 (A) and CD3-e (B) strongly staining the cells. C: EBER in situ hybridization is universally present, seen in the neoplastic cells in a destroyed vessel wall. D,E More about this image found in NK/T-CELL LYMPHOMA A,B: The neoplastic lymphoma cells show an NK-cell phen...

AMELOBLASTOMA Figure 5-43 AMELOBLASTOMA The neoplastic islands in ameloblastoma tend to become cystic, which can be appreciated both microscopically and macroscopically. The neoplasm infiltrates into medullary bone. More about this image found in AMELOBLASTOMA The neoplastic islands in ameloblastoma tend to become cysti...

KERATOAMELOBLASTOMA Figure 5-50 KERATOAMELOBLASTOMA The neoplastic islands show central keratinization. More about this image found in KERATOAMELOBLASTOMA The neoplastic islands show central keratinization.

CALCIFYING EPITHELIAL ODONTOGENIC TUMOR Figure 5-58 CALCIFYING EPITHELIAL ODONTOGENIC TUMOR Polygonal neoplastic cells with significant pleomorphism. More about this image found in CALCIFYING EPITHELIAL ODONTOGENIC TUMOR Polygonal neoplastic cells with si...

ODONTOGENIC MYXOMA Figure 5-103 ODONTOGENIC MYXOMA The neoplastic cells range from angular, to spindled and stellate but with minimal to no cytologic atypia. More about this image found in ODONTOGENIC MYXOMA The neoplastic cells range from angular, to spindled an...

CONVENTIONAL CHONDROSARCOMA Figure 5-193 CONVENTIONAL CHONDROSARCOMA A: Lobules of neoplastic cartilage infiltrate the submucosal soft tissue. B: Permeative growth into bone of atypical chondrocytes with nuclear hyperchromasia and binucleation. More about this image found in CONVENTIONAL CHONDROSARCOMA A: Lobules of neoplastic cartilage infiltrate ...

ATYPICAL FIBROXANTHOMA Figure 8-30 ATYPICAL FIBROXANTHOMA A: The neoplastic cells just below the intact epidermis have a storiform appearance. There is easily identified pleomorphism. B: Tumor cell spindling with basophilic cytoplasm. C: The surface (upper left) seems to blend with the tumor More about this image found in ATYPICAL FIBROXANTHOMA A: The neoplastic cells just below the intact epide...

BASOSQUAMOUS CARCINOMA Figure 8-35 BASOSQUAMOUS CARCINOMA A: The neoplastic cells form acanthotic endophytic projections into the dermis. Squamous differentiation is noted, along with areas of necrosis. B: The cells have a very high nuclear to cytoplasmic (N/C) ratio, giving a basaloid More about this image found in BASOSQUAMOUS CARCINOMA A: The neoplastic cells form acanthotic endophytic ...

MERKEL CELL CARCINOMA Figure 8-43 MERKEL CELL CARCINOMA The neoplastic cells show strong and diffuse, dot-like cytoplasmic CK20 immunoreactivity. More about this image found in MERKEL CELL CARCINOMA The neoplastic cells show strong and diffuse, dot-li...

CERUMINOUS ADENOMA Figure 8-71 CERUMINOUS ADENOMA A: All the neoplastic cells are strongly positive with pancytokeratin. B: The luminal cells tend to be highlighted with CK7 specifically. C: The basal-myoepithelial cells are highlighted by p63. D: GATA3 highlights the luminal-glandular cells More about this image found in CERUMINOUS ADENOMA A: All the neoplastic cells are strongly positive with ...

MIDDLE EAR NEUROENDOCRINE TUMOR Figure 8-103 MIDDLE EAR NEUROENDOCRINE TUMOR The neoplastic cells are variably reactive with a number of different immunohistochemical markers: pancytokeratin shows most of the cells positive, although some are nonreactive (A); CK7 highlights the inner luminal More about this image found in MIDDLE EAR NEUROENDOCRINE TUMOR The neoplastic cells are variably reactive...