ADRENAL CORTICAL NEOPLASM ASSOCIATED WITH CONGENITAL ADRENAL HYPERPLASIA Figure 2-13 ADRENAL CORTICAL NEOPLASM ASSOCIATED WITH CONGENITAL ADRENAL HYPERPLASIA A: A large adrenal cortical tumor present on the right is seen next to hyperplastic lipid-depleted adrenal cortex and a normal adrenal medu... More about this image found in ADRENAL CORTICAL NEOPLASM ASSOCIATED WITH CONGENITAL ADRENAL HYPERPLASIA A...

PHEOCHROMOCYTOMA: ANGIOINVASION Figure 8-47 PHEOCHROMOCYTOMA: ANGIOINVASION A,B: The presence of vascular invasion is a worrisome finding, but unlike in other neoplasms, it is not reliably associated with the development of metastatic disease. More about this image found in PHEOCHROMOCYTOMA: ANGIOINVASION A,B: The presence of vascular invasion is ...

PHEOCHROMOCYTOMA: NEUROENDOCRINE MARKERS Figure 8-37 PHEOCHROMOCYTOMA: NEUROENDOCRINE MARKERS The tumor cells express nuclear INSM1 (A), cytoplasmic synaptophysin (B), and cytoplasmic chromogranin A (C). These biomarkers indicate that this is a neuroendocrine neoplasm but are not specific for phe... More about this image found in PHEOCHROMOCYTOMA: NEUROENDOCRINE MARKERS The tumor cells express nuclear I...

NONFUNCTIONAL ADRENAL CORTICAL ADENOMA Figure 5-27 NONFUNCTIONAL ADRENAL CORTICAL ADENOMA A: The central portion of this adenoma shows extensive degeneration and hemorrhage with neovascularization. B: Cavernous channels in the hemorrhagic area have features suggestive of a vascular neoplasm. More about this image found in NONFUNCTIONAL ADRENAL CORTICAL ADENOMA A: The central portion of this aden...

CAROTID BODY PARAGANGLIOMA Figure 9-24 CAROTID BODY PARAGANGLIOMA A: The almost entirely spindle cell composition of this paraganglioma raises the possibility of mesenchymal and other spindle cell neoplasms. B: Reticulin stain highlights the spindle cell pattern. More about this image found in CAROTID BODY PARAGANGLIOMA A: The almost entirely spindle cell composition...

ADRENAL CORTICAL CARCINOMA Figure 6-7 ADRENAL CORTICAL CARCINOMA A large adrenal cortical carcinoma (ACC) from a 57-year-old woman simulated a renal cell carcinoma. The patient had no recognizable endocrine syndrome. Over half of the neoplasm was necrotic. More about this image found in ADRENAL CORTICAL CARCINOMA A large adrenal cortical carcinoma (ACC) from a...

UNDIFFERENTIATED NEUROBLASTOMA Figure 11-12 UNDIFFERENTIATED NEUROBLASTOMA Closely packed, poorly differentiated neuroblasts form solid sheets. Patterns such as this may cause confusion with other childhood neoplasms such as malignant lymphoma. Most nuclei have a single, small nucleolus. The tumo... More about this image found in UNDIFFERENTIATED NEUROBLASTOMA Closely packed, poorly differentiated neuro...

PHEOCHROMOCYTOMA ASSOCIATED WITH VON HIPPEL-LINDAU DISEASE (VHL): EXTENSIVE LIPID DEGENERATION Figure 8-12 PHEOCHROMOCYTOMA ASSOCIATED WITH VON HIPPEL-LINDAU DISEASE (VHL): EXTENSIVE LIPID DEGENERATION The gross appearance of this tumor is bright yellow, resembling an adrenal cortical neoplasm. T... More about this image found in PHEOCHROMOCYTOMA ASSOCIATED WITH VON HIPPEL-LINDAU DISEASE (VHL): EXTENSIVE...

URINARY BLADDER PARAGANGLIOMA Figure 9-22 URINARY BLADDER PARAGANGLIOMA A: This paraganglioma extends between muscle bundles in the bladder wall and is a potential mimic of other more aggressive neoplasms because of its growth pattern. B: Higher magnification of the tumor shows that most neoplas... More about this image found in URINARY BLADDER PARAGANGLIOMA A: This paraganglioma extends between muscle...

ADRENAL PSEUDOCYST Figure 12-23 ADRENAL PSEUDOCYST A: Adrenal pseudocyst shows degenerating recent and old hemorrhage. B: Fibrin-rich matter within an adrenal pseudocyst undergoing organization by endothelial cells emanating from the rich capillary plexus of attached cortex. C: CD34 immunostain... More about this image found in ADRENAL PSEUDOCYST A: Adrenal pseudocyst shows degenerating recent and old...