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Images
Figure 10-1
Published: 15 November 2023
MYXOMATOUS MITRAL VALVE DISEASE Figure 10-1 MYXOMATOUS MITRAL VALVE DISEASE The mitral valve is prominent and billowing in a diffuse fashion, with prominent annular dilatation. Valve translucency is completely lost with the myxomatous thickening. More about this image found in MYXOMATOUS MITRAL VALVE DISEASE The mitral valve is prominent and billowin...
Images
Figure 10-11
Published: 15 November 2023
MYXOMATOUS MITRAL VALVE DISEASE: SURGICAL SPECIMEN Figure 10-11 MYXOMATOUS MITRAL VALVE DISEASE: SURGICAL SPECIMEN Focal resection of the valve (P2 segment, in this case) produces a thickened, rubbery portion of leaflet that is characteristic of myxomatous disease. More about this image found in MYXOMATOUS MITRAL VALVE DISEASE: SURGICAL SPECIMEN Focal resection of the ...
Images
Figure 10-6
Published: 15 November 2023
MYXOMATOUS TRICUSPID VALVE DISEASE Figure 10-6 MYXOMATOUS TRICUSPID VALVE DISEASE Multifocal areas of rubbery leaflet thickening are seen around the tricuspid valve. More about this image found in MYXOMATOUS TRICUSPID VALVE DISEASE Multifocal areas of rubbery leaflet thi...
Images
Figure 10-10
Published: 15 November 2023
MYXOMATOUS VALVE DISEASE Figure 10-10 MYXOMATOUS VALVE DISEASE Bland valvular interstitial cells are seen in a myxoid backdrop throughout the expanded valvular spongiosa. More about this image found in MYXOMATOUS VALVE DISEASE Bland valvular interstitial cells are seen in a m...
Images
Figure 10-7
Published: 15 November 2023
MYXOMATOUS PULMONARY VALVE DISEASE Figure 10-7 MYXOMATOUS PULMONARY VALVE DISEASE There is focal thickening of the semilunar valve cusps with some tissue redundancy, imparting a “floppy” quality to the valve. More about this image found in MYXOMATOUS PULMONARY VALVE DISEASE There is focal thickening of the semilu...
Images
Figure 10-3
Published: 15 November 2023
MYXOMATOUS MITRAL VALVE DISEASE: ISOLATED ANTERIOR LEAFLET DISEASE Figure 10-3 MYXOMATOUS MITRAL VALVE DISEASE: ISOLATED ANTERIOR LEAFLET DISEASE The rubbery thickening is isolated to only the anterior mitral valve leaflet (black asterisk). More about this image found in MYXOMATOUS MITRAL VALVE DISEASE: ISOLATED ANTERIOR LEAFLET DISEASE The rub...
Images
Figure 10-5
Published: 15 November 2023
MYXOMATOUS MITRAL VALVE DISEASE: CORD RUPTURE Figure 10-5 MYXOMATOUS MITRAL VALVE DISEASE: CORD RUPTURE A single ruptured cord (yellow arrow) can lead to an unsupported (flail) valve segment and regurgitation. The most commonly involved segment is the P2 segment of the posterior leaflet. More about this image found in MYXOMATOUS MITRAL VALVE DISEASE: CORD RUPTURE A single ruptured cord (yell...
Images
Figure 10-9
Published: 15 November 2023
MYXOMATOUS AORTIC VALVE DISEASE Figure 10-9 MYXOMATOUS AORTIC VALVE DISEASE The spongy layer is expanded (double-headed arrow) and thicker than the two adjacent fibrous layers combined. The spongy tissue extends focally into the fibrosa (ventricularis) (black arrowhead), seen with Verhoeff-van More about this image found in MYXOMATOUS AORTIC VALVE DISEASE The spongy layer is expanded (double-heade...
Images
Figure 10-12
Published: 15 November 2023
MYXOMATOUS MITRAL VALVE DISEASE: ANNULOPLASTY REPAIR Figure 10-12 MYXOMATOUS MITRAL VALVE DISEASE: ANNULOPLASTY REPAIR Left: A C-shaped annuloplasty ring is installed around the posterior annulus to prevent annular dilatation and regurgitation. Right: A D-shaped ring may be used in cases More about this image found in MYXOMATOUS MITRAL VALVE DISEASE: ANNULOPLASTY REPAIR Left: A C-shaped annu...
Images
Figure 10-8
Published: 15 November 2023
MYXOMATOUS MITRAL VALVE DISEASE Figure 10-8 MYXOMATOUS MITRAL VALVE DISEASE The spongy layer (double-headed arrow) is expanded so that it is thicker than the two adjacent fibrous layers combined, along with focal extension of the spongy tissue into the fibrosa (ventricularis) (black arrowhead More about this image found in MYXOMATOUS MITRAL VALVE DISEASE The spongy layer (double-headed arrow) is ...
Images
Figure 10-4
Published: 15 November 2023
MITRAL ANNULAR CALCIFICATION Figure 10-4 MITRAL ANNULAR CALCIFICATION The myxomatous valve disease manifesting primarily in the posterior leaflet is associated with prominent annular calcification (yellow arrow), which is best seen on the radiograph (right). More about this image found in MITRAL ANNULAR CALCIFICATION The myxomatous valve disease manifesting prim...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch10
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
...AORTIC ANNULAR DILATATION Figure 10-13 AORTIC ANNULAR DILATATION The aortic valve annulus is markedly dilated (compared to the fairly normal pulmonary valve [PV]), such that the cusps no longer coapt in the middle (yellow arrow). MYXOMATOUS AORTIC VALVE DISEASE Figure 10-9 MYXOMATOUS AORTIC...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch46
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... or adjacent atrial tissue ( 41 , 43 ). They are considered to be hamartomas because there is often an admixture of fibrous tissue and a lack of encapsulation ( 44 ). Gross Findings. Valves with LHAV have been described as “billowy” or closely mimicking myxomatous valve disease, with the tumor imparting...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch31
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... primarily on the vascular pathology seen in MFS. Other cardiovascular findings, such as the associated cardiomyopathy or valvular findings (e.g., myxomatous mitral valve disease, annuloaortic ectasia) are discussed in chapters 19 and 10 , respectively. The other manifestations are beyond the scope...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch35
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... is typically regurgitant. Over time, it may develop focal prolapse with the microscopic features of a myxomatous valve. The mitral component has a trileaflet appearance ( fig. 35-13 ). Outlet Ventricular Septal Defect. The outlet septum is located beneath the right and left cusps of the aortic...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch12
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... valvular abnormality may be a stress point for the valve, putting the patient at risk for IE. The valve should, therefore, be carefully evaluated for underlying disease, such as bicuspid morphology, congenital dysplasia, or the presence of myxomatous disease ( fig. 12-5 ). Complications of NVE...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch38
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... also become more severe over time. Progressive annular dilatation and myxomatous changes in the atrioventricular valves can lead to regurgitation. With inverted ventricles, heart block can develop, as in congenitally corrected transposition. Secondary Cardiopulmonary Effects. Because pulmonary...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch06
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... as cause of sudden death in myxomatous mitral valve disease (see chapter 10 ) ( 103 ). Small vessel disease is a recognized finding in patients with hypertrophic cardiomyopathy and is seen with myofiber disarray and scarring (see chapter 15 ). Thoracic irradiation is typically administered...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch37
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... anomalies; or from annular dilatation. Microscopically, a regurgitant truncal valve typically has myxomatous features. Truncal valve stenosis, in contrast, is rare and is usually associated with nodular dysplasia of the cusps ( fig. 37-27 ). Truncal Artery. The truncal valve has three cusps in 70...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 16
Published: 01 August 2023
10.55418/9781933477282-11
ISBN-10: 1-933477-28-8
ISBN: 978-1-933477-28-2
... myxomas show recent hemorrhage. In a 2013 study, some myxomas were identified adjacent to sex cord-stromal tumors ( 7 ). The authors recommended that the myxomatous area should be mentioned if it is over 1 cm in size. Immunohistochemical Findings. The tumor cells are positive for vimentin and smooth...