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myofibroblastic
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Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-12
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... but has also been suggested to have a myofibroblastic origin ( 64 ). Tumors possibly related by proximity of their developmental precursors include teratoma ( 65 , 66 ), a malignant mixed germ cell tumor ( 67 ), and a primary tumor with the morphologic features of an extrarenal Wilms tumor reported in a 4...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-01
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... calcification is present occasionally. The histogenesis is not entirely settled; however, the morphology and immunohistochemical profile suggest origin from myofibroblasts in some cases ( 53 ). Hyaline Globules. Rarely, intracytoplasmic hyaline globules are reported within the cells of the zona...
Images
Published: 01 September 2024
CRYPTOCOCCAL INFLAMMATORY PSEUDOTUMOR Figure 20-7 CRYPTOCOCCAL INFLAMMATORY PSEUDOTUMOR There is a vaguely storiform proliferation of plump myofibroblasts and histiocytes (A) with intervening yeasts highlighted with an Alcian blue stain (B). More about this image found in CRYPTOCOCCAL INFLAMMATORY PSEUDOTUMOR There is a vaguely storiform prolife...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-20
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... number of yeasts. Inflammatory pseudotumors consisting of histiocytic and myofibroblastic cells with interspersed collagen and fungal yeasts have been documented in incompletely treated patients (especially those with HIV) and can histologically mimic a sarcoma ( fig. 20-7 ) ( 14 ). CRYPTOCOCCAL...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch50
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
...CARDIAC INFLAMMATORY MYOFIBROBLASTIC TUMOR Figure 50-1 CARDIAC INFLAMMATORY MYOFIBROBLASTIC TUMOR This polypoid growth (yellow arrowhead) within the left ventricular outflow tract extends to in volve the aortic valve (AV) and even prolapses into the right coronary ostium (yellow arrow). CARDIAC...
Images
Published: 01 January 2024
INFLAMMATORY MYOFIBROBLASTIC TUMOR Figure 11-16 INFLAMMATORY MYOFIBROBLASTIC TUMOR A: Low-power view shows a well-circumscribed spindle cell lesion that appears to have been “shelled out” at the time of excision. B: At intermediate power, the spindle cells are arrayed in loose fascicles. C: Hig... More about this image found in INFLAMMATORY MYOFIBROBLASTIC TUMOR A: Low-power view shows a well-circumsc...
Images
Published: 01 January 2024
MYOFIBROBLASTOMA WITH HETEROLOGOUS CHONDROID DIFFERENTIATION Figure 11-8 MYOFIBROBLASTOMA WITH HETEROLOGOUS CHONDROID DIFFERENTIATION Benign cartilage is present in the center of an otherwise unremarkable myofibroblastoma composed of myofibroblasts and collagen with admixed adipocytes. More about this image found in MYOFIBROBLASTOMA WITH HETEROLOGOUS CHONDROID DIFFERENTIATION Benign cartil...
Images
Published: 01 January 2024
MYOFIBROBLASTOMA, CELLULAR VARIANT Figure 11-5 MYOFIBROBLASTOMA, CELLULAR VARIANT This intermediate power view illustrates the characteristic pattern of myofibroblasts with interspersed bundles of collagen. The cellularity is greater than is typically seen. More about this image found in MYOFIBROBLASTOMA, CELLULAR VARIANT This intermediate power view illustrate...
Images
Published: 01 January 2024
FASCICULAR PSEUDOANGIOMATOUS STROMAL HYPERPLASIA (PASH) Figure 11-15 FASCICULAR PSEUDOANGIOMATOUS STROMAL HYPERPLASIA (PASH) Low-power (A) and high-power (B) views of an area of fascicular PASH in which the myofibroblasts aggregate into bundles. More about this image found in FASCICULAR PSEUDOANGIOMATOUS STROMAL HYPERPLASIA (PASH) Low-power (A) and ...
Images
Published: 01 January 2024
PSEUDOANGIOMATOUS STROMAL HYPERPLASIA (PASH) Figure 11-14 PSEUDOANGIOMATOUS STROMAL HYPERPLASIA (PASH) A: Low-power image shows irregular slit-like spaces lined by spindle cells embedded in a dense collagenous stroma, characteristic of PASH. B: Intermediate-power view of the myofibroblasts and f... More about this image found in PSEUDOANGIOMATOUS STROMAL HYPERPLASIA (PASH) A: Low-power image shows irre...
Images
Published: 01 January 2024
LYMPHOCYTIC MASTOPATHY Figure 2-3 LYMPHOCYTIC MASTOPATHY A: Low-power view illustrates the perilobular and perivascular lymphocytic infiltrate. Note the unusual appearance of the collagen in the stroma. B: Higher power of the perivascular lymphocytic infiltrate, which is sharply demarcated from ... More about this image found in LYMPHOCYTIC MASTOPATHY A: Low-power view illustrates the perilobular and p...
Images
Published: 01 January 2024
MYOFIBROBLASTOMA, PALISADED VARIANT Figure 11-6 MYOFIBROBLASTOMA, PALISADED VARIANT A: Low-power view shows a well circumscribed tumor with compact rows of myofibroblasts that characterize the palisaded variant. B,C: At intermediate (B) and high (C) power, the interspersed hypocellular or “Veroc... More about this image found in MYOFIBROBLASTOMA, PALISADED VARIANT A: Low-power view shows a well circums...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 18
Published: 01 January 2024
10.55418/9781933477367-11
ISBN-10: 1-933477-36-9
ISBN: 978-1-933477-36-7
... component of adipocytes is admixed within the myofibroblastic proliferation ( 5 ). Mammary ducts and lobules are typically absent within the tumor. MYOFIBROBLASTOMA Figure 11-1 MYOFIBROBLASTOMA A: At low power, the well-circumscribed border of the lesion is appreciated, as well as the thick collagen...
Images
Published: 15 November 2023
CARDIAC INFLAMMATORY MYOFIBROBLASTIC TUMOR Figure 50-1 CARDIAC INFLAMMATORY MYOFIBROBLASTIC TUMOR This polypoid growth (yellow arrowhead) within the left ventricular outflow tract extends to in volve the aortic valve (AV) and even prolapses into the right coronary ostium (yellow arrow). More about this image found in CARDIAC INFLAMMATORY MYOFIBROBLASTIC TUMOR This polypoid growth (yellow ar...
Images
Published: 15 November 2023
CARDIAC INFLAMMATORY MYOFIBROBLASTIC TUMOR Figure 50-2 CARDIAC INFLAMMATORY MYOFIBROBLASTIC TUMOR On low-power magnification, the tumor consists of a spindle cell proliferation in a polypoid configuration with abundant surface fibrin. More about this image found in CARDIAC INFLAMMATORY MYOFIBROBLASTIC TUMOR On low-power magnification, the...
Images
Published: 15 November 2023
CARDIAC INFLAMMATORY MYOFIBROBLASTIC TUMOR Figure 50-3 CARDIAC INFLAMMATORY MYOFIBROBLASTIC TUMOR The lesion exhibits myxoid change, which may accentuate the myofibroblastic quality of the cells. More about this image found in CARDIAC INFLAMMATORY MYOFIBROBLASTIC TUMOR The lesion exhibits myxoid chan...
Images
Published: 15 November 2023
CARDIAC INFLAMMATORY MYOFIBROBLASTIC TUMOR Figure 50-4 CARDIAC INFLAMMATORY MYOFIBROBLASTIC TUMOR The lesional cells are bland spindled myofibroblasts, with scattered inflammatory cells in the background. More about this image found in CARDIAC INFLAMMATORY MYOFIBROBLASTIC TUMOR The lesional cells are bland sp...
Images
Published: 15 November 2023
CARDIAC INFLAMMATORY MYOFIBROBLASTIC TUMOR Figure 50-5 CARDIAC INFLAMMATORY MYOFIBROBLASTIC TUMOR The lesional cells are reactive with antibodies directed against smooth muscle actin. More about this image found in CARDIAC INFLAMMATORY MYOFIBROBLASTIC TUMOR The lesional cells are reactive...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 18
Published: 01 January 2024
10.55418/9781933477367-02
ISBN-10: 1-933477-36-9
ISBN: 978-1-933477-36-7
..., and periductal (B-cell predominant) lymphoid infiltrates, as well as alterations of the collagenous stroma, keloidal-type collagen, and epithelioid myofibroblasts ( fig. 2-3 ) ( 6 ). The findings are subtle, but taken together, this constellation of features is sufficient to suggest the diagnosis. Correlation...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 18
Published: 01 January 2024
10.55418/9781933477367-05
ISBN-10: 1-933477-36-9
ISBN: 978-1-933477-36-7
... by atypical epithelial cells arrayed in single file, many with intracytoplasmic vacuoles and round, monotonous nuclei characteristic of invasive lobular carcinoma, which extended into this fibroadenoma from the adjacent breast parenchyma. Collagen and fibroblasts/myofibroblasts comprise the stromal...
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