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Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-08
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... result in hypertensive crisis, myocardial infarction, arrhythmias, Takotsubo cardiomyopathy, and acute heart failure. Tumors that secrete only epinephrine may be associated with hypotension ( 12 ). The classic features occur in only just over half of patients while some are asymptomatic ( 13...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-03
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... with hypertension, hypokalemia, and metabolic alkalosis with suppression of plasma renin activity. Primary aldosteronism is the most common cause of endocrine hypertension and is associated with a significant increase in the risk of cardiovascular complications, including myocardial and vascular endothelial...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-07
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... causes of myocarditis. Although enteroviruses and adenoviruses were the most frequent causes of viral myocarditis based on serologic studies, PCR testing has uncovered other viruses, such as human herpesvirus 6 (HHV6) and parvovirus B19 as important etiologies. Myocardial damage has been observed in up...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-16
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
..., bacterial organisms, and neutrophils, with surrounding necrosis and hemorrhage. They are usually found on the palms and soles. At autopsy, complications of infective endocarditis may be observed, including embolic phenomena such as CVAs, myocardial and splenic infarcts, and metastatic abscess formation...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-29
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... PHIL) Patients who die of chronic Chagas disease typically have an enlarged heart (with a mass of 400 to 800 g) and biventricular dilatation. There is also frequently an apical heart aneurysm with thrombosis. Myocardial histology reveals scattered foci of mononuclear inflammatory cells and eosinophils...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-10
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... findings included renal tubular necrosis, encephalitis with brain edema, pulmonary congestion and edema, and myocardial interstitial edema; many of these findings reflect terminal multiorgan failure ( 3 ). Intracytoplasmic inclusions were observed in hepatocytes ( fig. 10-2 ). MARBURG VIRUS HISTOPATHOLOGY...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-06
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... complications (depending on the region/nerves affected) include keratitis, retinal necrosis, and meningitis if the ophthalmic nerve was affected. Vasculopathy is a further complication and can result in cerebrovascular lesions (stroke) and myocardial infarction. Pathologic Findings The skin lesions caused...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-04
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... particles are present in surface (especially ciliated) and glandular epithelia of the trachea and larger bronchi ( fig. 4-4 ). The virus is rarely observed in cells in the alveolar spaces. Myocarditis (characterized by focal myocardial accumulations of lymphocytes with associated myocyte necrosis...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-12
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... in the infiltrate. (Courtesy of the CDC Infectious Disease Pathology Branch [IDPB]) Patients with pneumococcal septicemia can show adrenal gland hemorrhage and small myocardial abscesses, in which the bacteria are identified. Immunohistochemical assays using antibodies against S. pneumoniae demonstrate...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch07
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
...Table 7-1 CRITERIA FOR ACUTE MYOCARDIAL INFARCTION Rise and/or fall of serum cardiac troponin (cTn) with at least one value >99th percentile upper reporting limit, and one of the following:  Myocardial ischemic symptoms  New ischemic electrocardiographic changes  Development...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch08
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... RUPTURE: SURGICAL RESECTION Acute papillary muscle rupture often necessitates mitral valve replacement, with removal of the native mitral valve. VENTRICULAR CONTAINED RUPTURE (PSEUDOANEURYSM) Figure 8-12 VENTRICULAR CONTAINED RUPTURE (PSEUDOANEURYSM) The myocardial rupture is contained by intact...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch23
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... 23-3 RECREATIONAL DRUGS ASSOCIATED WITH MYOCARDIAL INJURY Drug Cardiotoxicity Amphetamines, cocaine, and ecstasy (3,4-Methylendixoymethamphetamine) Sympathetic activation Catecholamine depletion Direct myocytotoxicity Lysergic acid diethylamide Tachycardia, vasospasm...
Images
<span class="search-highlight">MYOCARDIAL</span> BRIDGING  <span class="search-highlight">Myocardial</span> bridge (arrows) over a large diagonal branc...
Published: 15 November 2023
MYOCARDIAL BRIDGING Figure 1-33 MYOCARDIAL BRIDGING Myocardial bridge (arrows) over a large diagonal branch. (Close-up of a short-axis myocardial slice.) More about this image found in MYOCARDIAL BRIDGING Myocardial bridge (arrows) over a large diagonal branc...
Images
ACUTE <span class="search-highlight">MYOCARDIAL</span> INFARCTIONS: EXTENT  Left: Transmural <span class="search-highlight">myocardial</span> infarctio...
Published: 15 November 2023
ACUTE MYOCARDIAL INFARCTIONS: EXTENT Figure 7-1 ACUTE MYOCARDIAL INFARCTIONS: EXTENT Left: Transmural myocardial infarction (MI) (yellow arrows) involving the left main coronary artery territory causes a massive infarction of nearly the entire left ventricle, with sparing of only the inferior thi... More about this image found in ACUTE MYOCARDIAL INFARCTIONS: EXTENT Left: Transmural myocardial infarctio...
Images
<span class="search-highlight">MYOCARDIAL</span> DECOMPOSITION  Top: Tissue gas bubbles extensively distort the m...
Published: 15 November 2023
MYOCARDIAL DECOMPOSITION Figure 3-8 MYOCARDIAL DECOMPOSITION Top: Tissue gas bubbles extensively distort the myocardium and epicardial fat. Bottom: Large Clostridium organisms are readily detected with routine hematoxylin and eosin (H&E) staining. More about this image found in MYOCARDIAL DECOMPOSITION Top: Tissue gas bubbles extensively distort the m...
Images
BASOPHILIC <span class="search-highlight">MYOCARDIAL</span> DEGENERATION  The sarcoplasmic material may appear am...
Published: 15 November 2023
BASOPHILIC MYOCARDIAL DEGENERATION Figure 4-1 BASOPHILIC MYOCARDIAL DEGENERATION The sarcoplasmic material may appear amorphous and chunky (left) or finely granular (right). (Left: hematoxylin and eosin [H&E]; right: periodic acid–Schiff [PAS] with diastase.) More about this image found in BASOPHILIC MYOCARDIAL DEGENERATION The sarcoplasmic material may appear am...
Images
<span class="search-highlight">MYOCARDIAL</span> COMPONENTS  Left ventricular cardiomyocytes are considerably lar...
Published: 15 November 2023
MYOCARDIAL COMPONENTS Figure 4-6 MYOCARDIAL COMPONENTS Left ventricular cardiomyocytes are considerably larger than interstitial cells, but interstitial cells appreciably outnumber the myocytes, as seen in this case with early fibrosis. Also, note the typical variation in nuclear size in adjacent... More about this image found in MYOCARDIAL COMPONENTS Left ventricular cardiomyocytes are considerably lar...
Images
<span class="search-highlight">MYOCARDIAL</span> INFLAMMATION AND REPAIR  Left: Inflammatory infiltrate primarily...
Published: 15 November 2023
MYOCARDIAL INFLAMMATION AND REPAIR Figure 4-18 MYOCARDIAL INFLAMMATION AND REPAIR Left: Inflammatory infiltrate primarily of neutrophils in 3-day-old infarct. Right: Fibrovascular granulation tissue with collagen deposition, at the edge of a 16-day-old infarct. More about this image found in MYOCARDIAL INFLAMMATION AND REPAIR Left: Inflammatory infiltrate primarily...
Images
MASSIVE IDIOPATHIC <span class="search-highlight">MYOCARDIAL</span> CALCIFICATION  Specimen (left) and its corres...
Published: 15 November 2023
MASSIVE IDIOPATHIC MYOCARDIAL CALCIFICATION Figure 4-20 MASSIVE IDIOPATHIC MYOCARDIAL CALCIFICATION Specimen (left) and its corresponding radiogram (right), in an adult. Calcified areas were cut with a hacksaw. More about this image found in MASSIVE IDIOPATHIC MYOCARDIAL CALCIFICATION Specimen (left) and its corres...
Images
ACUTE <span class="search-highlight">MYOCARDIAL</span> INFARCTION: LEFT ANTERIOR DESCENDING CORONARY ARTERY TERRI...
Published: 15 November 2023
ACUTE MYOCARDIAL INFARCTION: LEFT ANTERIOR DESCENDING CORONARY ARTERY TERRITORY Figure 7-2 ACUTE MYOCARDIAL INFARCTION: LEFT ANTERIOR DESCENDING CORONARY ARTERY TERRITORY Red-brown mottling of the myocardium (yellow arrows) extends from the anterior and anteroseptal left ventricle at the base (le... More about this image found in ACUTE MYOCARDIAL INFARCTION: LEFT ANTERIOR DESCENDING CORONARY ARTERY TERRI...