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Images
Published: 01 September 2024
SEPTICEMIC PLAGUE Figure 14-22 SEPTICEMIC PLAGUE Intravascular organisms in skeletal muscle are seen with an H&E stain (A) and Y. pestis immunohistochemistry (B). (Courtesy of the CDC IDPB) More about this image found in SEPTICEMIC PLAGUE Intravascular organisms in skeletal muscle are seen with...
Images
Published: 01 September 2024
MULTIPLE ORGAN INVOLVEMENT IN MALARIA Figure 27-3 MULTIPLE ORGAN INVOLVEMENT IN MALARIA Lung (A), liver (B), skeletal muscle (C), and brain (D) show dark brown hemozoin pigment. (Courtesy of the Centers for Disease Control and Prevention [CDC] Infectious Disease Pathology Branch [IDPB]) More about this image found in MULTIPLE ORGAN INVOLVEMENT IN MALARIA Lung (A), liver (B), skeletal muscle...
Images
Published: 01 September 2024
SARCOCYSTIS CYST IN SKELETAL MUSCLE Figure 28-11 SARCOCYSTIS CYST IN SKELETAL MUSCLE Multiple bradyzoites inside the cyst (A,B) are seen. Note the striking absence of inflammation. More about this image found in SARCOCYSTIS CYST IN SKELETAL MUSCLE Multiple bradyzoites ...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-28
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
.... SARCOCYSTOSIS General Considerations, Including Etiology and Synonyms Sarcocystis (previously Sarcosporidia) spp are zoonotic protozoans that infect humans either as a definitive or intermediate host ( 10 ). They were first described in the skeletal muscle of mice in 1843 and were thought...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-07
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
...VIRAL MYOCARDITIS General Considerations, Including Etiology and Synonyms Myocarditis, inflammation of the heart muscle frequently associated with myocyte injury and cardiac dysfunction, can have various causes, including viral infection. An integral part of the definitive diagnosis...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-03
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... NEUTROTROPIC FLAVIVIRUSES Virus Estimate of Asymptomatic Individuals Incubation Period Mild Disease Severe Disease Complications ZIKV Majority 3-14 days Headache, malaise, fever, conjunctivitis, rash, muscle and joint pain Lasts 2-7 days Encephalitis, Guillain-Barre syndrome, neuropathy...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-20
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... the yeasts are able to penetrate the blood brain barrier, central nervous system (CNS) involvement is a particularly serious consequence of systemic spread. Other sites of dissemination include the skin, genitourinary tract (especially the prostate gland), eye, bone, joints, muscle, endocrine organs...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-25
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
..., especially the heart (due to the large number of parasitic cysts present in muscle tissue) but also the kidney and liver. Hemopoietic stem cell transplants and, rarely, blood transfusions are other possible routes of transmission. Figure 25-1 illustrates the life cycle of T. gondii, with felids...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-01
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... cells. Laparoscopic excision of the mass reveals a spindle cell neoplasm with scattered lymphocytes ( fig. 1-5A,B ). Immunoperoxidase stains for smooth muscle actin and desmin are positive, while S-100 protein, CD34, CD117, and DOG1 stains are negative. Due to the patient’s HIV status, an Epstein-Barr...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-16
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... or friable ( fig. 16-3 ) ( 5 ). Occasionally, an abscess in the valve ring leads to fistula formation. In some instances, infection leads to perforation of a valve leaflet or the interventricular septum, as well as rupture of the chordae tendineae or papillary muscle. INFECTIVE ENDOCARDITIS VEGETATIONS...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-29
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
..., transforming into amastigotes. Amastigotes are found in many tissues, but they have a predilection for muscle. LIFE CYCLE OF TRYPANOSOMA CRUZI Figure 29-1 LIFE CYCLE OF TRYPANOSOMA CRUZI The amastigotes divide by fission, forming intracellular collections or “pseudocysts” that eventually...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-15
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
...; associated with diabetes mellitus and vascular insufficiency S. aureus, S. pyogenes, V. vulinficus, Aeromonas hydrophila and anaerobic streptococci Pyomyositis Infection of muscle accompanied by abscess formation; mostly a disease that occurs in adult patients with diabetes mellitus, connective...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-22
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
...-like yeasts may be polyarticular and occurs secondary to trauma, surgery, underlying joint disease, and joint prostheses ( 12 ). Skeletal muscle can also occasionally be involved. Pulmonary candidiasis is usually a result of hematogenous spread, although rare infections occur due to direct...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-26
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... of the gastrointestinal tract, as well as the biliary tree and gallbladder are most often involved in disseminated disease ( fig. 26-37 ). In the rare immunocompromised patient with disseminated infection involving skeletal muscle, sarcocystosis may enter the differential diagnosis; this is excluded by careful histologic...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-08
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... muscle tumors tumors Multiple sclerosis Sjorgen syndrome Systemic lupus erythematosus Rheumatoid arthritis Chronic inflammatory bowel disease The two most frequent risk factors for EBV-driven neoplasia are immunosuppression due to organ transplantation and HIV infection. In many instances, EBV...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-17
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... ). Necrotizing suppurative abscesses that later progress to more granulomatous inflammation can be present in the liver, spleen, skeletal muscle, and other organs. The kidneys can reveal interstitial nephritis, glomerulonephritis, and acute tubular necrosis. SYSTEMIC TULAREMIA Figure 17-11 SYSTEMIC TULAREMIA...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-13
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
.... In advanced cases, there may also be brain ring hemorrhages and microthrombi, as well as degeneration of cardiac and skeletal muscle myocytes. In the GIT, the histologic differential diagnosis of typhoid fever includes Whipple disease, mycobacterial (especially Mycobacterium avium-intracellulare...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-27
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... accumulation in the liver (A) and spleen (B), with striking dark brown to black tissue discoloration. (Courtesy of Prof. I. W. Simson, University of Pretoria, Pretoria, South Africa) MULTIPLE ORGAN INVOLVEMENT IN MALARIA Figure 27-3 MULTIPLE ORGAN INVOLVEMENT IN MALARIA Lung (A), liver (B), skeletal muscle...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-14
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... the formation of abundant fibrin thrombi. SEPTICEMIC PLAGUE Figure 14-22 SEPTICEMIC PLAGUE Intravascular organisms in skeletal muscle are seen with an H&E stain (A) and Y. pestis immunohistochemistry (B). (Courtesy of the CDC IDPB) Immunohistochemical assays are helpful in differentiating...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-04
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... inflammation and necrosis, and in the immunocompromised (e.g., renal transplant patients), there may be associated tubulointerstitial nephritis and prostatitis. In disseminated disease, other organs such as the liver, CNS, heart, and rarely, pancreas, skeletal muscle, and synovium, may be involved. The liver...
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