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mucinous

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Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-06
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
..., with a predominance of cortisol-secreting tumors; sex steroid hormone secretion has never been described. Grossly, the tumor is characterized by the presence of gelatinous material, to a variable extent, that corresponds to the abundant extracellular connective tissue mucin that characterizes its histology ( fig. 6...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-09
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... cytoplasmic bubbles and vacuoles that may mimic mucin droplets or signet ring cells (see fig. 9-23 ). Other potentially confounding morphologic changes are intratumoral congestion and hemorrhage secondary to ligation of blood vessels during surgery ( fig. 9-28 ), or necrosis from preoperative embolization...
Images
ALLERGIC FUNGAL RHINOSINUSITIS  There is <span class="search-highlight">mucin</span> with abundant eosinophils (A...
Published: 01 September 2024
ALLERGIC FUNGAL RHINOSINUSITIS Figure 21-31 ALLERGIC FUNGAL RHINOSINUSITIS There is mucin with abundant eosinophils (A). Fungal hyphae are typically scant (B). More about this image found in ALLERGIC FUNGAL RHINOSINUSITIS There is mucin with abundant eosinophils (A...
Images
<span class="search-highlight">MUCIN</span> BLEBS MIMICKING <em>CRYPTOSPORIDIUM</em>  Gastric epithelium ...
Published: 01 September 2024
MUCIN BLEBS MIMICKING CRYPTOSPORIDIUM Figure 26-29 MUCIN BLEBS MIMICKING CRYPTOSPORIDIUM Gastric epithelium showing apical mucin blebs, which can mimic cryptosporidial organisms with an H&E stain. More about this image found in MUCIN BLEBS MIMICKING CRYPTOSPORIDIUM Gastric epithelium ...
Images
<em>CRYPTOSPORIDIUM</em> ORGANISMS  The compact, round, basophilic ...
Published: 01 September 2024
CRYPTOSPORIDIUM ORGANISMS Figure 26-30 CRYPTOSPORIDIUM ORGANISMS The compact, round, basophilic and “stuck-on” appearance of cryptosporidial organisms differentiates them from mucin blebs at a morphologic level. More about this image found in CRYPTOSPORIDIUM ORGANISMS The compact, round, basophilic ...
Images
<em>C. DIFFICILE</em> PSEUDOMEMBRANOUS COLITIS  Ballooned crypts (A...
Published: 01 September 2024
C. DIFFICILE PSEUDOMEMBRANOUS COLITIS Figure 13-26 C. DIFFICILE PSEUDOMEMBRANOUS COLITIS Ballooned crypts (A,B) with intraluminal mucin, neutrophils, and foci of early ulceration. Intercryptal necrosis with fibrin deposition (C). More about this image found in C. DIFFICILE PSEUDOMEMBRANOUS COLITIS Ballooned crypts (A...
Images
LATER-STAGE <em>C. DIFFICILE</em> PSEUDOMEMBRANOUS COLITIS  Submuco...
Published: 01 September 2024
LATER-STAGE C. DIFFICILE PSEUDOMEMBRANOUS COLITIS Figure 13-27 LATER-STAGE C. DIFFICILE PSEUDOMEMBRANOUS COLITIS Submucosal edema and typical “volcano” or “mushroom” lesion (A) consisting of a protuberant lamellated exudate of fibrin, mucin, red blood cells, and neutrophils (B). More about this image found in LATER-STAGE C. DIFFICILE PSEUDOMEMBRANOUS COLITIS Submuco...
Images
LYMPHOGRANULOMA VENEREUM PROCTITIS  Endoscopic biopsies with marked inflamm...
Published: 01 September 2024
LYMPHOGRANULOMA VENEREUM PROCTITIS Figure 18-14 LYMPHOGRANULOMA VENEREUM PROCTITIS Endoscopic biopsies with marked inflammatory expansion of the lamina propria, epithelial mucin depletion, and minimal crypt architectural distortion. (Courtesy of Dr. L. Voltaggio, Johns Hopkins Medical Institution... More about this image found in LYMPHOGRANULOMA VENEREUM PROCTITIS Endoscopic biopsies with marked inflamm...
Images
<em>G. DUODENALIS</em> ORGANISMS  <em>G. duodenalis</em> or...
Published: 01 September 2024
G. DUODENALIS ORGANISMS Figure 26-20 G. DUODENALIS ORGANISMS G. duodenalis organisms may occasionally be identified in the stomach (arrow), usually in the setting of achlorhydria, and may be mistaken for mucin droplets by the unwary (A: H&E, B: methylene blue stain. Courtesy of Dr. H. Venbrux, Camp Hill, PA) More about this image found in G. DUODENALIS ORGANISMS G. duodenalis or...
Images
NORORVIRUS INFECTION  A,B: The duodenal mucosa shows mild villous broadenin...
Published: 01 September 2024
NORORVIRUS INFECTION Figure 5-15 NORORVIRUS INFECTION A,B: The duodenal mucosa shows mild villous broadening, an increase in lamina propria chronic inflammatory cells, a mild increase in intraepithelial lymphocytes, and focal surface epithelial degeneration. C,D: Colonic biopsies demonstrate nea... More about this image found in NORORVIRUS INFECTION A,B: The duodenal mucosa shows mild villous broadenin...
Images
ADENOCARCINOMA IN SITU (AIS)  A: Biopsy fragment shows numerous endocervica...
Published: 01 September 2024
ADENOCARCINOMA IN SITU (AIS) Figure 9-38 ADENOCARCINOMA IN SITU (AIS) A: Biopsy fragment shows numerous endocervical glands with AIS predominantly on the right. B: Glands with AIS in the lower half show depleted mucin, several mitoses, and apoptosis. C: P16 is positive in glands with AIS and is... More about this image found in ADENOCARCINOMA IN SITU (AIS) A: Biopsy fragment shows numerous endocervica...
Images
ADENOCARCINOMA IN SITU (AIS)  A: Biopsy fragment shows numerous endocervica...
Published: 01 September 2024
ADENOCARCINOMA IN SITU (AIS) Figure 9-38 ADENOCARCINOMA IN SITU (AIS) A: Biopsy fragment shows numerous endocervical glands with AIS predominantly on the right. B: Glands with AIS in the lower half show depleted mucin, several mitoses, and apoptosis. C: P16 is positive in glands with AIS and is... More about this image found in ADENOCARCINOMA IN SITU (AIS) A: Biopsy fragment shows numerous endocervica...
Images
HISTOLOGIC DETECTION OF <em>H. PYLORI</em>  A: Many basophilic <ita
Published: 01 September 2024
HISTOLOGIC DETECTION OF H. PYLORI Figure 13-32 HISTOLOGIC DETECTION OF H. PYLORI A: Many basophilic H. pylori bacilli are easily identified on a routine hematoxylin and eosin (H&E) stain in the mucin adjacent to this gastric biopsy. B: A methylene blue stain is an example of a monochromatic stain, which can be used to highlight the organisms. C: A silver-based Warthin-Starry stain shows numerous small curved H. pylori bacilli, clearly visible against a counterstained background. D: An H. pylori immunoperoxidase stain confirms abundant organisms adjacent to the superficial gastric epithelium. More about this image found in HISTOLOGIC DETECTION OF H. PYLORI A: Many basophilic
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BACILLARY DYSENTERY DUE TO <em>SHIGELLA FLEXNERI</em> AND <em>S</em>...
Published: 01 September 2024
BACILLARY DYSENTERY DUE TO SHIGELLA FLEXNERI AND SALMONELLA Figure 13-2 BACILLARY DYSENTERY DUE TO SHIGELLA FLEXNERI AND SALMONELLA A: Low-power histology of a colon biopsy shows preserved crypt architecture, mild lamina propria congestion, focal neutrophil infiltration, and superficial plasmacytosis. Note the basal crypt neutrophil exocytosis. B: Bacillary dysentery due to nontyphi Salmonella, with more prominent neutrophil infiltration, superficial/midmucosal crypt abscess formation, crypt destruction, mucin depletion, and crypt epithelial reactive change. Unlike inflammation in chronic inflammatory bowel disease, there is an absence of deep crypt abscess formation, basal plasmacytosis, and other features of chronicity. More about this image found in BACILLARY DYSENTERY DUE TO SHIGELLA FLEXNERI AND S...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-26
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
.... Acute giardiasis is associated with a rapid onset of diarrhea, which is often copious and watery. There is frequently also malaise, flatulence, bloating, nausea, anorexia, and abdominal cramping. The course is typically afebrile and not associated with the presence of pus, blood, or mucin...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-19
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... a mass with dark grains draining from fistulous tracts Requires surgical treatment in addition to antimycotics Eye Keratitis Trauma Clouding of cornea, loss of vision Paranasal sinuses Allergic sinusitis Atopy Nasal congestion, rhinorrhea, postnasal drip, nasal polyp, allergic mucin...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-13
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... and nonspecific changes, such as mucosal hyperemia or edema. On histology, endoscopic biopsy material typically reveals no or mild and nonspecific reactive changes, such as villous blunting and broadening, surface epithelial vacuolization and disarray, epithelial mucin depletion, and focal epithelial degeneration...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-20
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... on the host immune status. In many immune-competent and otherwise healthy individuals, sampled primary lung lesions grossly may merely reveal a circumscribed focus of fibrosis. If fungal yeasts are abundant, an exudate, consolidation, or mass with mucinous consistency (gelatinous form of cryptococcosis) may...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-16
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... syndrome) and hypercoagulability states, particularly those associated with malignancy. Adenocarcinomas, particularly mucin-secreting tumors of the lung, pancreas and biliary tract, ovary, gastrointestinal tract, and of unknown primary, are the most frequent underlying malignancies ( 1 ). Epidemiology...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-23
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... of classic histoplasmosis includes infection by other fungal yeasts, such as Cryptococcus spp (distinguished by a mucoid capsule, which is highlighted on mucin stains), Candida glabrata, Blastomyces spp, Talaromyces marneffei, Emergomyces spp, and Pneumocystis jirovecii...