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Book Chapter
Sinonasal Cavity
Available to PurchaseSeries: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 22
Published: 01 June 2025
10.55418/9781933477619-1
ISBN: 978-1-933477-61-9
..., positive with TLE1 and SS18-SSX, and lack a CD34 and STAT6 reaction ( 296 , 482 ). Treatment and Prognosis. There are several multivariable risk stratification models for prognostication ( 454 , 458 , 483 , 484 ), although they are not optimized for the relatively smaller size of sinonasal tract tumors...
Book Chapter
Oral Cavity
Available to PurchaseSeries: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 22
Published: 01 June 2025
10.55418/9781933477619-4
ISBN: 978-1-933477-61-9
... . Joint effects of intensity and duration of cigarette smoking on the risk of head and neck cancer: a bivariate spline model approach . Oral Oncol 2019 ; 94 : 47 - 57 . 15. Ghantous Y , Schussel JL , Brait M . Tobacco and alcohol-induced epigenetic changes in oral carcinoma...
Book Chapter
Jaw
Available to PurchaseSeries: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 22
Published: 01 June 2025
10.55418/9781933477619-5
ISBN: 978-1-933477-61-9
..., vertebral anomalies such as hemivertebrae, fusion or elongation of the vertebral bodies, modeling defects of the hands and feet Cleft lip or palate, polydactyly Cardiac or ovarian fibroma Medulloblastoma Other skeletal abnormalities: Sprengel deformity, marked pectus deformity, marked...
Book Chapter
Ear and Temporal Bone
Available to PurchaseSeries: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 22
Published: 01 June 2025
10.55418/9781933477619-8
ISBN: 978-1-933477-61-9
... in primary melanomas . J Natl Cancer Inst 2003 ; 95 : 1878 - 90 . 298. Greenwald HS , Friedman EB , Osman I . Superficial spreading and nodular melanoma are distinct biological entities: a challenge to the linear progression model . Melanoma Res 2012 ; 22 : 1 - 8 . 299...
Book Chapter
Hypopharynx, Larynx, and Trachea
Available to PurchaseSeries: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 22
Published: 01 June 2025
10.55418/9781933477619-6
ISBN: 978-1-933477-61-9
... carbohydrate scaffold for vocal fold medialization in an ovine model . OTO Open 2023 ; 7 : e69 . 45. Yeretsian RA , Blodgett TM , Branstetter BF 4th , Roberts MM , Meltzer CC . Teflon-induced granuloma: a false-positive finding with PET resolved with combined PET and CT...
Book Chapter
Hereditary Predisposition to Adrenal Cortical Lesions
Available to PurchaseSeries: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-07
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... in ARMC5-mutant in vitro models is, however, in contrast to the association between ARMC5-inactivating mutations and higher cortisol levels in patients. The relative inefficiency to produce cortisol in ARMC5-mutated cells is probably compensated by the larger adrenal mass observed...
Book Chapter
Adrenal Cortical Carcinoma
Available to PurchaseSeries: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-06
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... ). An integrated model for malignancy risk assessment based on tumor size and tumor-to-liver uptake SUVmax ratio has been proposed recently to calculate an individual malignancy risk for a patient-based decision-making process ( 98 ). Currently, the American College of Radiology committee on incidental...
Book Chapter
Other Adrenal Neoplasms and Tumor-Like Lesions
Available to PurchaseSeries: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-12
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... techniques and mathematical models have been proposed for differentiating these lesions ( 99 ). Pathology Pitfalls and Common Differential Diagnoses As with primary adrenal tumors, adrenal metastases are increasingly recognized during life with the aid of high-resolution imaging studies such as CT scan...
Book Chapter
Physiology, Development, and Anatomy of the Adrenal Glands
Available to PurchaseSeries: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-01
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... emerging from the intermediolateral column (IML) of the spinal cord. They then travel to the developing adrenal glands (AG) guided by those axons, which will also provide innervation of the medulla (DA = dorsal aorta). (Courtesy of Drs. M. Kastriti and I. Adameyko, Vienna, Austria) This model may help...
Book Chapter
Neuroblastoma, Ganglioneuroblastoma, and Ganglioneuroma
Available to PurchaseSeries: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-11
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... Pharmacol 2012 ; 70 : 477 - 86 . 100. Iyer R , Wehrmann L , Golden RL , et al . Entrectinib is a potent inhibitor of Trk-driven neuroblastomas in a xenograft mouse model . Cancer Lett 2016 ; 372 : 179 - 86 . 101. Bove KE , McAdams AJ . Composite ganglioneu...
Book Chapter
Hemorrhagic Fevers
Available to PurchaseSeries: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-10
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... of virus . N Engl J Med 2006 ; 355 : 909 - 19 . 3. Glaze E , Roy M , Dalrymple L , Lanning L . A comparison of the pathogenesis of Marburg virus disease in humans and nonhuman primates and evaluation of the suitability of these animal models for predicting clinical efficacy...
Book Chapter
Heart
Available to PurchaseSeries: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-07
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... microorganisms primarily affect different cells: cardiomyocytes, endothelial cells, or inflammatory cells ( Table 7-2 ). As depicted in figure 7-1 , the pathogenesis of viral myocarditis is divided into three phases based on animal models and clinical observations ( 9 ). During the acute phase, there is direct...
Book Chapter
Skin and Soft Tissue
Available to PurchaseSeries: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-06
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
...Table 6-1 DIFFERENCES BETWEEN HUMAN HERPESVIRUSES 1, 2, AND 3 HSV1 and 2 VZV Genome size; G+C content ~152Kbp; -67%(Approximately 50% genetic homology between HSV1 and 2) ~125Kbp; -47% Host range Broad Restricted (animal models do not replicate human disease) Route...
Book Chapter
Prion Diseases
Available to PurchaseSeries: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-02
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... Y . Creutzfeldt-Jakob disease . Neuropathology 2017 ; 37 : 174 - 88 . 10. Brandner S , Jaunmuktane Z . Prion disease: experimental models and reality . Acta Neuropathol 2017 ; 133 : 197 - 222 . 11. WHO manual for surveillance of human transmissible spongiform...
Book Chapter
Gastrointestinal Tract
Available to PurchaseSeries: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-22
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... 2017 ; 38 : 264 - 76 . 10. Koh AY . Murine models of Candida gastrointestinal colonization and dissemination . Eukaryot Cell 2013 ; 12 : 1416 - 22 . 11. Slavik T . Human immunodeficiency virus-related gastrointestinal pathology: a southern Africa perspective with review...
Book Chapter
Skin and Soft Tissue
Available to PurchaseSeries: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-15
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... . 15. Rebman AW , Aucott JN . Post-treatment Lyme disease as a model for persistent symptoms in Lyme disease . Front Med (Lausanne) 2020 ; 7 : 57 . 16. Duray P , Chandler F . Lyme disease . In: Connor D , Chandler F , Schwartz D , Manz H , Lack...
Book Chapter
Central Nervous System
Available to PurchaseSeries: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-03
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... , Ehrhardt D . Progress toward poliomyelitis eradication—Afghanistan, January 2018-May 2019 . MMWR Morb Mortal Wkly Rep 2019 ; 68 : 729 - 33 . 34. Shen L , Chen CY , Huang D , et al . Pathogenic events in a nonhuman primate model of oral poliovirus infection leading...
Book Chapter
Skin and Soft Tissue
Available to PurchaseSeries: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-24
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... precludes exclusion of a mycelial phase at room temperature. In animal models, intradermal injection of the fungus obtained from human lesions results in localized multiplication of the yeasts. The organism elicits TGF-β (transforming growth factor-β), which suppresses macrophage lytic activity...
Book Chapter
Gastrointestinal Tract
Available to PurchaseSeries: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-13
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... Infect 2002 ; 4 : 1125 - 32 . 29. Savarino SJ , Fasano A , Robertson DC , Levine MM . Enteroaggregative Escherichia coli elaborate a heat-stable enterotoxin demonstrable in an in vitro rabbit intestinal model . J Clin Invest 1991 ; 87 : 1450 - 5 . 30. Darfeuille...
Book Chapter
Respiratory Tract
Available to PurchaseSeries: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-12
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... changes. Pathologic features that have been observed in sepsis animal models, as well as patients who died from culture-proven sepsis include interstitial hemorrhages, thrombosis, edema, cellular apoptosis (including lymphocytes and hepatocytes), and foci of necrosis (presumably due to hypoperfusion...
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