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COMBINED NEUROTIZED NEVUS  There is a <span class="search-highlight">mixed</span> population of nests of small co...
Published: 01 February 2024
COMBINED NEUROTIZED NEVUS Figure 10-12 COMBINED NEUROTIZED NEVUS There is a mixed population of nests of small conventional epithelioid melanocytes (arrow) and fusiform spindle cells. More about this image found in COMBINED NEUROTIZED NEVUS There is a mixed population of nests of small co...
Images
<span class="search-highlight">MIXED</span> DESMOPLASTIC MELANOMA  A: There is a diffusely infiltrative fibrosing...
Published: 01 February 2024
MIXED DESMOPLASTIC MELANOMA Figure 16-6 MIXED DESMOPLASTIC MELANOMA A: There is a diffusely infiltrative fibrosing tumor involving the dermis and subcutis. B: Close-up view of the area within the inset of A. Focal features of melanoma in situ are characterized by the presence of nests and pageto... More about this image found in MIXED DESMOPLASTIC MELANOMA A: There is a diffusely infiltrative fibrosing...
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<span class="search-highlight">MIXED</span> DESMOPLASTIC MELANOMA  A densely cellular nodule of tumor cells witho...
Published: 01 February 2024
MIXED DESMOPLASTIC MELANOMA Figure 16-7 MIXED DESMOPLASTIC MELANOMA A densely cellular nodule of tumor cells without intervening fibrous stroma is juxtaposed to a fibrosing tumor cell component of lower cell density, typical of desmoplastic melanoma. More about this image found in MIXED DESMOPLASTIC MELANOMA A densely cellular nodule of tumor cells witho...
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<span class="search-highlight">MIXED</span> DESMOPLASTIC MELANOMA  A: Invasive desmoplastic melanoma involves the...
Published: 01 February 2024
MIXED DESMOPLASTIC MELANOMA Figure 16-8 MIXED DESMOPLASTIC MELANOMA A: Invasive desmoplastic melanoma involves the dermis and subcutis. B,C: The tumor contains stroma-rich cell-poor areas (B) as well as more densely cellular areas (C). More about this image found in MIXED DESMOPLASTIC MELANOMA A: Invasive desmoplastic melanoma involves the...
Images
COMBINED BLUE NEVUS  Biphenotypic intradermal melanocytic nevus with a <span class="search-highlight">mixe</span>...
Published: 01 February 2024
COMBINED BLUE NEVUS Figure 8-11 COMBINED BLUE NEVUS Biphenotypic intradermal melanocytic nevus with a mixed population of conventional small epithelioid melanocytes and a pigmented population with fusiform melanocytes with common BN-like features. More about this image found in COMBINED BLUE NEVUS Biphenotypic intradermal melanocytic nevus with a mixe...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-16
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
... – 5 ). In mixed variants, a part of the tumor is densely cellular and lacks prominent or any fibroplasia. CLINICAL FEATURES DM accounts for less than 4 percent of all melanomas ( 6 – 9 ). It most often develops in chronically sun-damaged skin of the head and neck region of elderly Caucasians...
Images
ACRAL NEVUS FROM THE FOOT OF A TEENAGER  A: The silhouette of the lesion sh...
Published: 01 February 2024
ACRAL NEVUS FROM THE FOOT OF A TEENAGER Figure 5-3 ACRAL NEVUS FROM THE FOOT OF A TEENAGER A: The silhouette of the lesion shows a mixed lentiginous junctional and nested growth pattern of melanocytes. B: In the center of the lesion are several melanocytes in the spinous and granular cell layer.... More about this image found in ACRAL NEVUS FROM THE FOOT OF A TEENAGER A: The silhouette of the lesion sh...
Images
VULVAR NEVUS  A: Compound nevus with nests at the dermoepidermal junction t...
Published: 01 February 2024
VULVAR NEVUS Figure 5-5 VULVAR NEVUS A: Compound nevus with nests at the dermoepidermal junction that vary in size and shape and are focally confluent. There is a mixed population of melanocytes in the dermis composed of larger (*) and smaller cells (arrow). B: There are areas of stromal fibrosi... More about this image found in VULVAR NEVUS A: Compound nevus with nests at the dermoepidermal junction t...
Images
ACRAL MELANOMA WITH SYRINGOTROPISM: IN SITU AND INVASIVE  A: The melanoma i...
Published: 01 February 2024
ACRAL MELANOMA WITH SYRINGOTROPISM: IN SITU AND INVASIVE Figure 14-8 ACRAL MELANOMA WITH SYRINGOTROPISM: IN SITU AND INVASIVE A: The melanoma in situ displays a mixed lentiginous, nested, and pagetoid pattern. It extends along the epithelial stromal junction of eccrine ducts (white arrows). B,C:... More about this image found in ACRAL MELANOMA WITH SYRINGOTROPISM: IN SITU AND INVASIVE A: The melanoma i...
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MYOFIBROBLASTOMA, LIPOMATOUS VARIANT  A: Low-power view shows a <span class="search-highlight">mixed</span> lipom...
Published: 01 January 2024
MYOFIBROBLASTOMA, LIPOMATOUS VARIANT Figure 11-3 MYOFIBROBLASTOMA, LIPOMATOUS VARIANT A: Low-power view shows a mixed lipomatous and spindle cell lesion. B: High power shows the bland spindle cell component, interspersed between adipocytes. Scattered mast cells offer a clue to the correct diagno... More about this image found in MYOFIBROBLASTOMA, LIPOMATOUS VARIANT A: Low-power view shows a mixed lipom...
Images
INVASIVE BREAST CARCINOMA, NST, GRADE 2  This tumor is composed of a <span class="search-highlight">mix</span> of...
Published: 01 January 2024
INVASIVE BREAST CARCINOMA, NST, GRADE 2 Figure 8-2 INVASIVE BREAST CARCINOMA, NST, GRADE 2 This tumor is composed of a mix of tubules and solid nests. The tumor cell nuclei display greater variability than the prior case. More about this image found in INVASIVE BREAST CARCINOMA, NST, GRADE 2 This tumor is composed of a mix of...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-10
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
... papule (arrow) shows bluish discoloration. C: Dermoscopy of the nevus and separate dark papule (arrow). MICROSCOPIC FINDINGS Common scenarios of mixed nevus phenotypes within the same clinical lesion include those of a conventional acquired or congenital nevus combined with a blue nevus ( 1 – 3 ), deep...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-05
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
... OF A TEENAGER A: The silhouette of the lesion shows a mixed lentiginous junctional and nested growth pattern of melanocytes. B: In the center of the lesion are several melanocytes in the spinous and granular cell layer. Differential Diagnosis. The difficulty of distinguishing atypical acral nevi from...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-23
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
... evidence of regression is a loss of melanocytes related to inflammation. A lymphocytic infiltrate typically reflects early regression. Later stages of regression are characterized by a mix of dermal fibrosis and chronic inflammation, often involving pigment-laden macrophages. The epidermis may...
Images
ROSAI-DORFMAN DISEASE  A: A low-power view of a core needle biopsy shows fi...
Published: 01 January 2024
ROSAI-DORFMAN DISEASE Figure 2-4 ROSAI-DORFMAN DISEASE A: A low-power view of a core needle biopsy shows fibrous breast parenchyma with a mixed chronic inflammatory cell infiltrate. B: Higher power reveals the presence of histiocytes, lymphocytes, and plasma cells. C: High power shows a histioc... More about this image found in ROSAI-DORFMAN DISEASE A: A low-power view of a core needle biopsy shows fi...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-14
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
... more difficult. Dermoscopy is useful for the distinction of an acral nevus from melanoma ( 16 , 17 ). Subungual melanomas tend to display a parallel ridge pattern of pigmentation ( fig. 14-3 ), while acral nevi tend to display a furrow or mixed furrow and lattice-like pattern. ACRAL MELANOMA Figure 14...
Images
PROBABLE SQUAMOUS METAPLASIA OF LACTIFEROUS DUCTS (SMOLD)  A: Low-power vie...
Published: 01 January 2024
PROBABLE SQUAMOUS METAPLASIA OF LACTIFEROUS DUCTS (SMOLD) Figure 13-2 PROBABLE SQUAMOUS METAPLASIA OF LACTIFEROUS DUCTS (SMOLD) A: Low-power view shows blood and inflammatory cells. B: At higher power, the inflammation is noted to be mixed, composed of lymphocytes, neutrophils, and multi-nucleat... More about this image found in PROBABLE SQUAMOUS METAPLASIA OF LACTIFEROUS DUCTS (SMOLD) A: Low-power vie...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-21
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
... melanomas are characterized by prominent growth around nerves peripheral to the tumor. Neurotropism can be seen with any type of melanoma, but is most commonly associated with mixed spindle cell and desmoplastic melanomas. Signet ring cell melanomas or melanomas with glandular features are exceedingly rare...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-19
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
... ). Some are predominantly composed of fusiform cells ( fig. 19-3 ), while others display a predominant large epithelioid cell phenotype ( figs. 19-4 , 19-5 ). Many show mixed spindle and epithelioid tumor cells. While most spitzoid melanomas involve both the epidermis and dermis, some are entirely...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-12
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
..., there is a mix, but in some lesions, the pagetoid pattern dominates and in others, the nested growth pattern (see figs. 12-3 – 12-6 ). Most SSMs measure more than 4 mm in horizontal surface dimension, but a rare lesion is smaller. The silhouette of SSM is usually asymmetric ( 3 , 8 ). The asymmetry...