MELANOMA IN SITU WITH FOCAL MICROINVASION Figure 12-10 MELANOMA IN SITU WITH FOCAL MICROINVASION Rare small aggregates of melanocytes are seen in the superficial dermis (arrow) similar in appearance to the intraepidermal tumor cells. More about this image found in MELANOMA IN SITU WITH FOCAL MICROINVASION Rare small aggregates of melanoc...

LENTIGO MALIGNA MELANOMA WITH SINGLE CELL MICROINVASION Figure 13-11 LENTIGO MALIGNA MELANOMA WITH SINGLE CELL MICROINVASION Melanoma in situ is associated with isolated atypical melanocytes (arrows) in a fibrosed papillary dermis. More about this image found in LENTIGO MALIGNA MELANOMA WITH SINGLE CELL MICROINVASION Melanoma in situ i...

PLEOMORPHIC LOBULAR CARCINOMA IN SITU AND MICROINVASIVE CARCINOMA Figure 4-18 PLEOMORPHIC LOBULAR CARCINOMA IN SITU AND MICROINVASIVE CARCINOMA A lobule is expanded by atypical, dyshesive epithelial cells with large pleomorphic nuclei. Present in the stroma adjacent to this focus are several scat... More about this image found in PLEOMORPHIC LOBULAR CARCINOMA IN SITU AND MICROINVASIVE CARCINOMA A lobule...

MICROINVASIVE CARCINOMA Figure 8-28 MICROINVASIVE CARCINOMA A: Low-power image of a cyst with an adjacent small, glandular proliferation. B: At higher power, the glandular proliferation appears somewhat infiltrative and the epithelial cells are atypical. C: A smooth muscle myosin heavy chain (S... More about this image found in MICROINVASIVE CARCINOMA A: Low-power image of a cyst with an adjacent smal...

DUCTAL CARCINOMA IN SITU WITH MICROINVASION Figure 8-25 DUCTAL CARCINOMA IN SITU WITH MICROINVASION A: At low power, a portion of a field of extensive high nuclear grade DCIS with desmoplasia and stromal inflammation is seen. Microinvasion can be difficult to identify in cases of this type. B,C:... More about this image found in DUCTAL CARCINOMA IN SITU WITH MICROINVASION A: At low power, a portion of ...

FLAT EPITHELIAL ATYPIA WITH MICROINVASION Figure 8-27 FLAT EPITHELIAL ATYPIA WITH MICROINVASION Intermediate-power image illustrates variably dilated acini lined by monomorphic epithelial cells, diagnostic of flat epithelial atypia. In addition, there are a few angulated glands and nests of micro... More about this image found in FLAT EPITHELIAL ATYPIA WITH MICROINVASION Intermediate-power image illustr...

DUCTAL CARCINOMA IN SITU: HIGH NUCLEAR GRADE WITH MICROINVASION Figure 3-27 DUCTAL CARCINOMA IN SITU: HIGH NUCLEAR GRADE WITH MICROINVASION A: Intermediate-power view illustrates high nuclear grade DCIS with involvement of lobules (top of field). The inflammatory cell infiltrate is prominent. Sin... More about this image found in DUCTAL CARCINOMA IN SITU: HIGH NUCLEAR GRADE WITH MICROINVASION A: Interme...

LOBULAR CARCINOMA IN SITU (LCIS) WITH MICROINVASION Figure 8-26 LOBULAR CARCINOMA IN SITU (LCIS) WITH MICROINVASION A: Extensive LCIS is present in this case, characterized by large nests of cells with round, monomorphic nuclei. The presence of an inflammatory cell infiltrate should prompt closer... More about this image found in LOBULAR CARCINOMA IN SITU (LCIS) WITH MICROINVASION A: Extensive LCIS is p...

DUCTAL CARCINOMA IN SITU INVOLVING LOBULES Figure 8-29 DUCTAL CARCINOMA IN SITU INVOLVING LOBULES DCIS involving lobules can be a mimic of invasive or microinvasive carcinoma. Observing the lobulocentric arrangement of the tumor cell nests and the presence of a myoepithelial cell layer aid in the... More about this image found in DUCTAL CARCINOMA IN SITU INVOLVING LOBULES DCIS involving lobules can be a...

ENCAPSULATED PAPILLARY CARCINOMA Figure 7-25 ENCAPSULATED PAPILLARY CARCINOMA A: At low power, a large encapsulated papillary carcinoma occupies much of the field; in the center of the image a single gland is seen, perhaps raising concern for microinvasion. B: At high power, inflammatory cells a... More about this image found in ENCAPSULATED PAPILLARY CARCINOMA A: At low power, a large encapsulated pap...

MYOEPITHELIAL CELL STAINS IN ADENOSIS Figure 6-11 MYOEPITHELIAL CELL STAINS IN ADENOSIS A: In this case of lobular carcinoma in situ (LCIS) involving adenosis, the arrangement of some of the epithelial cell nests suggests invasive carcinoma rather than LCIS in adenosis. B: A SMMHC stain highligh... More about this image found in MYOEPITHELIAL CELL STAINS IN ADENOSIS A: In this case of lobular carcinoma...

CARDIAC AMYLOIDOSIS: DEPOSITION PATTERNS Figure 21-14 CARDIAC AMYLOIDOSIS: DEPOSITION PATTERNS Deposition patterns of cardiac amyloidosis shown are pericellular-type (A), nodular (B), obstructive microinvasive (C), and endocardial (D). (All: sulfated Alcian blue staining.) More about this image found in CARDIAC AMYLOIDOSIS: DEPOSITION PATTERNS Deposition patterns of cardiac am...