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Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-12
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... in some of the more active areas. Adenomatoid Tumor. Primary adenomatoid tumor of the adrenal gland is a rare benign tumor of mesothelial origin that typically occurs in adult men. Approximately 30 cases have been reported ( 38 ). On gross examination, the tumors are smooth, white, and homogeneous...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-05
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
..., these latter two markers are also expressed in mesothelial cells and related neoplasms that can also manifest in the adrenal gland alone or in association with adrenal cortical adenoma ( 53 ). ADRENAL CORTICAL ADENOMA IN CUSHING SYNDROME Figure 5-50 ADRENAL CORTICAL ADENOMA IN CUSHING SYNDROME Steroidogenic...
Images
Figure 51-24
Published: 15 November 2023
MESOTHELIAL INCIDENTAL CARDIAC EXCRESCENCE Figure 51-24 MESOTHELIAL INCIDENTAL CARDIAC EXCRESCENCE Left: MICE consist of fibrin, mesothelial cells, and plump epithelioid histiocytes. Right: The histiocytes can be particularly prominent in some examples. More about this image found in MESOTHELIAL INCIDENTAL CARDIAC EXCRESCENCE Left: MICE consist of fibrin, m...
Images
Figure 27-13
Published: 15 November 2023
BENIGN PAPILLARY MESOTHELIAL PROLIFERATION Figure 27-13 BENIGN PAPILLARY MESOTHELIAL PROLIFERATION Above: Reactive changes of the pericardium include benign papillary proliferations that grossly manifest as little whiskers on the pericardial surface. Right: Histologically, they consist More about this image found in BENIGN PAPILLARY MESOTHELIAL PROLIFERATION Above: Reactive changes of the ...
Images
Figure 51-5
Published: 15 November 2023
PERICARDIAL CYST Figure 51-5 PERICARDIAL CYST Top: The single layer of bland, flat mesothelial cells lines a fibrotic stroma. Bottom: A prominent thick-walled artery and dense lymphoplasmacytic inflammation are seen focally within the cyst wall. More about this image found in PERICARDIAL CYST Top: The single layer of bland, flat mesothelial cells li...
Images
Figure 51-22
Published: 15 November 2023
MESOTHELIAL INCIDENTAL CARDIAC EXCRESCENCE (MICE) Figure 51-22 MESOTHELIAL INCIDENTAL CARDIAC EXCRESCENCE (MICE) Small and mucoid, these lesions may be adherent or free floating within the pericardium or within a cardiac chamber. More about this image found in MESOTHELIAL INCIDENTAL CARDIAC EXCRESCENCE (MICE) Small and mucoid, these ...
Images
Figure 51-23
Published: 15 November 2023
MESOTHELIAL INCIDENTAL CARDIAC EXCRESCENCE Figure 51-23 MESOTHELIAL INCIDENTAL CARDIAC EXCRESCENCE At low power (left), these lesions have both cellular and paucicellular areas, which are similarly seen at higher power (right). More about this image found in MESOTHELIAL INCIDENTAL CARDIAC EXCRESCENCE At low power (left), these lesi...
Images
Figure 26-1
Published: 15 November 2023
NORMAL PERICARDIUM Figure 26-1 NORMAL PERICARDIUM A normal section of pericardium shows a monolayer of mesothelial cells on top of an even layer of collagen, with small blood vessels throughout. More about this image found in NORMAL PERICARDIUM A normal section of pericardium shows a monolayer of me...
Images
Figure 24-19
Published: 15 November 2023
RIGHT VENTRICULAR PERFORATION Figure 24-19 RIGHT VENTRICULAR PERFORATION The presence of fibroadipose tissue and mesothelial lining in an endomyocardial biopsy typically indicates perforation. However, most of the time this is of no clinical consequence and heals spontaneously. More about this image found in RIGHT VENTRICULAR PERFORATION The presence of fibroadipose tissue and meso...
Images
Figure 56-20
Published: 15 November 2023
PERICARDIAL MESOTHELIOMA: IMMUNOHISTOCHEMISTRY Figure 56-20 PERICARDIAL MESOTHELIOMA: IMMUNOHISTOCHEMISTRY The malignant cells are diffusely reactive with antibodies directed against calretinin (left) and WT-1 (nuclear) (right), helping to confirm mesothelial differentiation. More about this image found in PERICARDIAL MESOTHELIOMA: IMMUNOHISTOCHEMISTRY The malignant cells are dif...
Images
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch51
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... on the limbus of the fossa ovalis. PERICARDIAL CYST Figure 51-5 PERICARDIAL CYST Top: The single layer of bland, flat mesothelial cells lines a fibrotic stroma. Bottom: A prominent thick-walled artery and dense lymphoplasmacytic inflammation are seen focally within the cyst wall. PERICARDIAL CYST...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch27
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... phase of organizing fibrinous pericarditis contains exuberant fibrinous exudate. Right: Chronically, the exudate organizes and becomes fibrotic, with perpendicularly oriented vasculature and mesothelial surface hyperplasia. CHOLESTEROL PERICARDITIS Figure 27-12 CHOLESTEROL PERICARDITIS Numerous...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch56
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
...Table 56-1 IMMUNOHISTOCHEMICAL DIFFERENTIATION OF MESOTHELIOMA FROM CARCINOMA Mesothelial Markers Carcinoma Markers Calretinin B72.3 WT-1 BerEP4 (EpCAM) D2-40 (podoplanin) BG8 GATA3 CEA CK5/6 CD15 (LeuM1) Claudin-4 MOC31 PERICARDIAL MESOTHELIOMA Figure 56-16...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch26
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... A normal section of pericardium shows a monolayer of mesothelial cells on top of an even layer of collagen, with small blood vessels throughout. PERICARDIAL CONSTRICTION: INFLAMMATION Figure 26-7 PERICARDIAL CONSTRICTION: INFLAMMATION Constrictive pericarditis is often accompanied by a chronic...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch48
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... of cystic tumors of the AV node have been known for more than 100 years, although they have gone by different names. These various terms arose to reflect an evolving understanding of the etiology of these peculiar tumors. They were thought to be of mesothelial and endothelial origin and hence have been...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch54
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... of reactive mesothelial cells may be trapped in areas of an angiosarcoma. Angiosarcomas of the pericardium can be difficult to diagnose in pericardial biopsies and may be mistaken for mesothelioma. Immunohistochemical stains for calretinin, WT1, and cytokeratin 5/6 (mesothelial markers) help to differentiate...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch24
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... and plasma cells that closely mimic rejection and Quilty effect. C: In situ hybridization for Epstein-Barr virus (L26) confirms the nature of the infiltrate. RIGHT VENTRICULAR PERFORATION Figure 24-19 RIGHT VENTRICULAR PERFORATION The presence of fibroadipose tissue and mesothelial lining...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch23
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... the procedure usually targets the septum under fluoroscopic guidance, sampling of the free wall comes with a risk of puncture. As above, this is more of a risk when in the right heart. Identification of fibroadipose tissue and mesothelial cells is common when evaluating endomyocardial biopsies, but these small...
Images
Figure 4-28
Published: 01 August 2023
WELL-DIFFERENTIATED PAPILLARY MESOTHELIAL TUMOR Figure 4-28 WELL-DIFFERENTIATED PAPILLARY MESOTHELIAL TUMOR More about this image found in WELL-DIFFERENTIATED PAPILLARY MESOTHELIAL TUMOR