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mesenchymal

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Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 11
Publisher: American Registry of Pathology
Published: 01 June 2022
DOI: 10.55418/9781933477190-5
ISBN-10: 1-933477-19-9
ISBN: 978-1-933477-19-0
... ; 19 : 321 - 7 . 121. Rapicetta   C , Lococo   F , Carlinfante   G , Ricchetti   T , Paci   M . Extraskeletal osteosarcoma arising from the pleura . Lung   2017 ; 195 : 523 - 5 . 122. Jain   A , Safaya   R , Jagan   C , Sharma   SK . Extraskeletal mesenchymal...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 11
Publisher: American Registry of Pathology
Published: 01 June 2022
DOI: 10.55418/9781933477190-2
ISBN-10: 1-933477-19-9
ISBN: 978-1-933477-19-0
... the capacity to be both epithelioid (rounded) and sarcomatoid (spindle shaped), as well as undergoing differentiation to other mesenchymal elements (e.g., osteosarcomatous differentiation within mesothelioma). For these reasons, the previous edition of this Fascicle primarily classified tumors first...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 11
Publisher: American Registry of Pathology
Published: 01 June 2022
DOI: 10.55418/9781933477190-1
ISBN-10: 1-933477-19-9
ISBN: 978-1-933477-19-0
... increasing evidence that mesothelial cells show a remarkable degree of plasticity. They have the potential to generate other mesenchymal-derived cell lines ( 25 ), behave as vascular progenitor (so-called MesoT) cells ( 26 ), and regulate homeostasis ( 27 ). Obstruction of lymphatics may result...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 11
Publisher: American Registry of Pathology
Published: 01 June 2022
DOI: 10.55418/9781933477190-8
ISBN-10: 1-933477-19-9
ISBN: 978-1-933477-19-0
... as metaplasia within the submesothelial mesenchyme, although there also appears to be an increased risk of DPL after uterine morcellation ( 104 , 105 ). Microscopically, there are well-demarcated firm white nodules that, on microscopy, consist of cytologically bland smooth muscle cells with a fascicular...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 11
Publisher: American Registry of Pathology
Published: 01 June 2022
DOI: 10.55418/9781933477190-7
ISBN-10: 1-933477-19-9
ISBN: 978-1-933477-19-0
... that clear cell and endometrioid patterns arise from endometriosis ( 59 ). Recent molecular analyses support common origin of serous carcinomas with and without STIC lesions ( 60 ). Rare primary peritoneal mesenchymal tumors can occur. As an example, epithelioid hemangioendothelioma of the peritoneum can...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 11
Publisher: American Registry of Pathology
Published: 01 June 2022
DOI: 10.55418/9781933477190-3
ISBN-10: 1-933477-19-9
ISBN: 978-1-933477-19-0
... and the sarcomatoid cells have a mesenchymal or spindle cell morphology. Tumors are classified as biphasic when both cell types are present. The term diffuse malignant mesothelioma in relation to any of the major subtypes is acceptable. Epithelial should not be used instead of epithelioid, sarcomatous should...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 7
Publisher: American Registry of Pathology
Published: 01 September 2021
DOI: 10.55418/9781933477121-2
ISBN-10: 1-933477-12-1
ISBN: 978-1-933477-12-1
...As in soft tissue, mesenchymal tumors of the skin are rare and characterized by extreme clinicopathologic heterogeneity. Mesenchymal tumors arising in the deeper soft tissues may also affect the skin, however, their incidence is variable. Although liposarcomas are the most frequent sarcomas of deep...
Images
HISTOGENESIS OF SARCOMATOID CARCINOMA OF THE URINARY BLADDER  There are two...
Published: 01 November 2021
HISTOGENESIS OF SARCOMATOID CARCINOMA OF THE URINARY BLADDER Figure 3-96 HISTOGENESIS OF SARCOMATOID CARCINOMA OF THE URINARY BLADDER There are two main hypotheses for the histogenesis of this tumor: divergent differentiation of monoclonal tumor and “collision” of synchronous urothelial and mesen... More
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 10
Publisher: American Registry of Pathology
Published: 01 January 2022
DOI: 10.55418/9781933477183-10
ISBN-10: 1-933477-18-0
ISBN: 978-1-933477-18-3
.... The simplest are based on the Scheuer method ( Table 10-3 ) ( 18 , 19 ). More complex schema incorporate cellular localization of iron, as hepatocellular versus mesenchymal (sinusoidal lining cells and/or portal macrophages) and mixed hepatocellular/mesenchymal accumulation ( 16 , 20 ). Iron storage in each...
Images
GIANT CELL CYSTITIS  The lamina propria often contains variable numbers of ...
Published: 01 November 2021
GIANT CELL CYSTITIS Figure 3-6 GIANT CELL CYSTITIS The lamina propria often contains variable numbers of multi nucleated giant cells. Atypical stromal mesenchymal cells are present (inset). More
Images
ANAPLASTIC SARCOMA OF THE KIDNEY  A: At low power, the lesion has prominent...
Published: 01 November 2021
ANAPLASTIC SARCOMA OF THE KIDNEY Figure 1-120 ANAPLASTIC SARCOMA OF THE KIDNEY A: At low power, the lesion has prominent cystic architecture. B: The cyst walls have primitive neoplastic spindle cell stroma. C: Spindle cell stroma condenses into cellular mesenchymal nodules. D: Anaplastic cytol... More
Images
ANAPLASTIC SARCOMA OF THE KIDNEY  A: At low power, the lesion has prominent...
Published: 01 November 2021
ANAPLASTIC SARCOMA OF THE KIDNEY Figure 1-120 ANAPLASTIC SARCOMA OF THE KIDNEY A: At low power, the lesion has prominent cystic architecture. B: The cyst walls have primitive neoplastic spindle cell stroma. C: Spindle cell stroma condenses into cellular mesenchymal nodules. D: Anaplastic cytol... More
Images
<span class="search-highlight">MESENCHYMAL</span> CHONDROSARCOMA  Above: Axial CT image shows a soft tissue mass ...
Published: 01 October 2021
MESENCHYMAL CHONDROSARCOMA Figure 7-49 MESENCHYMAL CHONDROSARCOMA Above: Axial CT image shows a soft tissue mass with central calcification in the medial aspect of the left thigh. Right: Reformatted coronal CT of a mesenchymal chondrosarcoma of the thoracic vertebrae. More
Images
<span class="search-highlight">MESENCHYMAL</span> CHONDROSARCOMA  A large tumor causes fusiform expansion of the ...
Published: 01 October 2021
MESENCHYMAL CHONDROSARCOMA Figure 7-50 MESENCHYMAL CHONDROSARCOMA A large tumor causes fusiform expansion of the diaphysis of a long bone. There are hard mineralized deposits and areas of necrosis and hemorrhage. More
Images
<span class="search-highlight">MESENCHYMAL</span> CHONDROSARCOMA  A: Areas with more or less differentiated carti...
Published: 01 October 2021
MESENCHYMAL CHONDROSARCOMA Figure 7-51 MESENCHYMAL CHONDROSARCOMA A: Areas with more or less differentiated cartilage are admixed with cellular areas containing undifferentiated small round cells. The tumor entraps preexisting necrotic host bone. B: Areas with cartilaginous differentiation gradu... More
Images
<span class="search-highlight">MESENCHYMAL</span> CHONDROSARCOMA  A: The tumor cells are small, with coarse chrom...
Published: 01 October 2021
MESENCHYMAL CHONDROSARCOMA Figure 7-52 MESENCHYMAL CHONDROSARCOMA A: The tumor cells are small, with coarse chromatin without a prominent nucleolus. The cytoplasm is scant and is often absent, giving the impression of “naked nuclei.” The undifferentiated component can predominate, and distinction... More
Images
<span class="search-highlight">MESENCHYMAL</span> CHONDROSARCOMA  Left: The spindle cell areas are seen.  Right: ...
Published: 01 October 2021
MESENCHYMAL CHONDROSARCOMA Figure 7-53 MESENCHYMAL CHONDROSARCOMA Left: The spindle cell areas are seen. Right: As opposed to dedifferentiated chondrosarcoma, a sharp interface between both components is lacking: the cartilaginous areas gradually merge with the round cell component. More
Images
<span class="search-highlight">MESENCHYMAL</span> CHONDROSARCOMA  CD99 is positive.
Published: 01 October 2021
MESENCHYMAL CHONDROSARCOMA Figure 7-54 MESENCHYMAL CHONDROSARCOMA CD99 is positive. More
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<span class="search-highlight">MESENCHYMAL</span> CHONDROSARCOMA  Focal expression of desmin can cause confusion ...
Published: 01 October 2021
MESENCHYMAL CHONDROSARCOMA Figure 7-55 MESENCHYMAL CHONDROSARCOMA Focal expression of desmin can cause confusion with rhabdomyosarcoma. More
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PHOSPHATURIC <span class="search-highlight">MESENCHYMAL</span> TUMOR OF THE VERTEBRA  Axial CT demonstrates a lyt...
Published: 01 October 2021
PHOSPHATURIC MESENCHYMAL TUMOR OF THE VERTEBRA Figure 17-26 PHOSPHATURIC MESENCHYMAL TUMOR OF THE VERTEBRA Axial CT demonstrates a lytic lesion with cortical break centered in the posterior elements of the lumbar vertebral body (arrows). More