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Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 18
Published: 01 January 2024
10.55418/9781933477367-14
ISBN-10: 1-933477-36-9
ISBN: 978-1-933477-36-7
...-negative breast cancer . N Engl J Med   2011 ; 364 : 412 - 21 . 7. Cote   R , Giuliano   AE , Hawes   D , et al . ACOSOG Z0010: a multicenter prospective study of sentinel node (SN) and bone marrow (BM) micrometastases in women with clinical T1/T2 N0 M0 breast cancer . J Clin Oncol...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 18
Published: 01 January 2024
10.55418/9781933477367-15
ISBN-10: 1-933477-36-9
ISBN: 978-1-933477-36-7
... , et al . Effect of occult metastases on survival in node-negative breast cancer . N Engl J Med   2011 ; 364 : 412 - 21 . 56. Cote   R , Giuliano   AE , Hawes   D , et al . ACOSOG Z0010: a multicenter prospective study of sentinel node (SN) and bone marrow (BM) micrometastases...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch57
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... light chain crystals ( fig. 57-19 ). The crystalline nature is most evident ultrastructurally ( fig. 57-20 ). The cells are most frequent in bone marrow, lungs, lymph nodes, thymus gland, and spleen. The monoclonal light chains are typically kappa isotype, with no specific heavy chain association...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch04
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... to originating from resident interstitial fibroblasts, they are also derived from vascular endothelial cells and bone marrow cells, including circulating progenitor cells, monocytes, and fibrocytes ( 15 ). In the left ventricle, interstitial fibrosis can be age-related. In the elderly, it may result in increased...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch29
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... of malignant hypertension, thrombotic thrombocytopenia purpura, hemolytic uremic syndrome, autoimmune rheumatologic disorders (especially scleroderma), drug toxicity, radiation, and bone marrow transplantation. Clinically, malignant hypertension is not always a constant finding. Findings of thrombotic...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch06
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... of calcified valve fragments after surgery, and bone marrow embolism. Paradoxical embolism, or traversal of a patent foramen ovale, is a requirement for embolic material originating from the peripheral venous circulation to lodge into the coronary arteries. In clinical series of coronary embolism, the most...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch05
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... bone occurs in 19 percent of calcified arteries, osteoid with bone marrow is relatively uncommon in coronary arterial atherosclerotic lesions ( 102 ). This low rate in coronary arteries is likely a reflection of the underlying different disease process, as peripheral vascular disease is largely caused...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch39
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... incidence of recurrent significant tricuspid regurgitation than monocusp repairs ( 8 ). Intraoperative autologous bone marrow-derived mononuclear stem cell therapy may be associated with improved biventricular function postoperatively ( 9 ). When tricuspid valve repair is not feasible, replacement can...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 15
Published: 01 March 2023
10.55418/9781933477275-01
ISBN-10: 1-933477-27-X
ISBN: 978-1-933477-27-5
... the pancreas, bone marrow, immune system, and skeleton ( 182 ). Mutations in the SBDS gene on chromosome 7q11 are found in most patients ( 181 ). Presenting symptoms in infancy are related to pancreatic insufficiency, specifically malabsorption and steatorrhea, but these symptoms resolve with age...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 15
Published: 01 March 2023
10.55418/9781933477275-13
ISBN-10: 1-933477-27-X
ISBN: 978-1-933477-27-5
... in the pancreas with no bone marrow involvement. Most cases occurred in women, presenting with a median age of 37 years (range, 19 to 48 years) ( 156 , 159 ). Most individuals presented with pancreatic head involvement causing epigastric pain and jaundice. Resection is performed when the diagnosis...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 14
Published: 01 February 2023
10.55418/9781933477268-5
ISBN-10: 1-933477-26-1
ISBN: 978-1-933477-26-8
.... The prognosis is dependent upon histotype and stage. Myeloid Sarcoma Definition.  Myeloid sarcoma is a solid tumor composed of myeloid blasts occurring outside the bone marrow. It is also referred to as granulocytic sarcoma. General Features. Myeloid sarcoma uncommonly involves the lower...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 14
Published: 01 February 2023
10.55418/9781933477268-3
ISBN-10: 1-933477-26-1
ISBN: 978-1-933477-26-8
... site of disease (primary cervical lymphoma) or manifest as secondary involvement. Myeloid sarcoma is a solid tumor of malignant myeloid cells occurring at an anatomic location other than the bone marrow. General Features. The female genital tract is a common site of involvement by hematologic...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 13
Published: 01 November 2022
10.55418/9781933477251-1
ISBN-10: 1-933477-25-3
ISBN: 978-1-933477-25-1
... ). The disease phenotype is heterogeneous, varying from single bone lesions to multisystem disease with organ failure and substantial mortality, often due to concurrent development of hemophagocytic lymphohistiocytosis ( 417 , 418 ). Liver, bone marrow, and/or splenic involvement impart a worse prognosis...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 13
Published: 01 November 2022
10.55418/9781933477251-4
ISBN-10: 1-933477-25-3
ISBN: 978-1-933477-25-1
..., myelolipomatous changes in the adrenal cortex, and Carney complex with bilateral pigmented adrenocortical disease. Myelolipomatous changes are often associated with hypercortisolism. The presence of fat cells, lymphocytes, and bone marrow elements, including myeloid and erythroid precursors, help make...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 12
Published: 01 August 2022
10.55418/9781933477220-09
ISBN-10: 1-933477-22-9
ISBN: 978-1-933477-22-0
... involvement during follow-up, primarily to lymph nodes, skin, opposite testis, bone marrow, spleen, adrenal gland, and central nervous system, with 70 percent dying of disease ( 54 ). There is no statistically significant difference in survival for those with initial clinical stages I and II disease compared...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 12
Published: 01 August 2022
10.55418/9781933477220-04
ISBN-10: 1-933477-22-9
ISBN: 978-1-933477-22-0
... cartilage ( fig. 4-170B ), and, less commonly, adipose tissue. Rarely, a tumor consists almost exclusively of nodules of cartilage ( fig. 4-170C ). Foci of neuroglia, sometimes with ependymal differentiation, are common. Bone is less frequent but may contain hematopoietic marrow. In rare cases of metastatic...
Images
VENO-OCCLUSIVE DISEASE (SINUSOIDAL OBSTRUCTIVE SYNDROME)  There is marked z...
Published: 01 January 2022
VENO-OCCLUSIVE DISEASE (SINUSOIDAL OBSTRUCTIVE SYNDROME) Figure 1-78 VENO-OCCLUSIVE DISEASE (SINUSOIDAL OBSTRUCTIVE SYNDROME) There is marked zone 3 congestion and thrombosis of the central veins. The patient was status post-bone marrow transplant. More about this image found in VENO-OCCLUSIVE DISEASE (SINUSOIDAL OBSTRUCTIVE SYNDROME) There is marked z...
Images
SINUSOIDAL CONGESTION: SYSTEMIC AUTOIMMUNE DISEASE  This biopsy was origina...
Published: 01 January 2022
SINUSOIDAL CONGESTION: SYSTEMIC AUTOIMMUNE DISEASE Figure 1-80 SINUSOIDAL CONGESTION: SYSTEMIC AUTOIMMUNE DISEASE This biopsy was originally signed out as suggesting vascular outflow disease. When work-up revealed no evidence of vascular outflow disease, the case was sent for consultation. This p... More about this image found in SINUSOIDAL CONGESTION: SYSTEMIC AUTOIMMUNE DISEASE This biopsy was origina...
Images
PHOSPHATURIC MESENCHYMAL TUMOR  A: The tumor has replaced the bone <span class="search-highlight">marrow</span> s...
Published: 01 October 2021
PHOSPHATURIC MESENCHYMAL TUMOR Figure 17-30 PHOSPHATURIC MESENCHYMAL TUMOR A: The tumor has replaced the bone marrow spaces and encases preexisting trabecular bone. Unlike many of the bone tumors, an infiltrative growth pattern in a phosphaturic mesenchymal tumor is not diagnostic of malignancy. ... More about this image found in PHOSPHATURIC MESENCHYMAL TUMOR A: The tumor has replaced the bone marrow s...
Images
SYSTEMIC MASTOCYTOSIS: BONE <span class="search-highlight">MARROW</span> INVOLVEMENT  Paratrabecular aggregates o...
Published: 01 September 2021
SYSTEMIC MASTOCYTOSIS: BONE MARROW INVOLVEMENT Figure 3-117 SYSTEMIC MASTOCYTOSIS: BONE MARROW INVOLVEMENT Paratrabecular aggregates of spindle-shaped mast cells are seen (A,B). These show metachromatic staining with Giemsa (C) and express CD117 (D). More about this image found in SYSTEMIC MASTOCYTOSIS: BONE MARROW INVOLVEMENT Paratrabecular aggregates o...