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Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-06
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... with the liver) ( 79 ). Table 6-1 IMAGING CHARACTERISTICS OF BENIGN VERSUS MALIGNANT ADRENAL MASSES a Characteristic Likely Benign Suspicious for Malignancy Size Small (<4 cm) Large (>4 cm) Shape Round or oval Irregular Margins Smooth Irregular Texture Homogeneous...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-11
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... be achieved, and resection or debulking is performed following chemotherapy. Such resections frequently arrive piecemeal in the pathology laboratory and resection margins are not an issue with regard to pathology reporting. Instead, the amount of chemotherapy effect should be assessed upon gross morphology...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-02
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... palpation ( 42 , 43 ) and is the most cost-effective and quickest imaging technique. In cases of partial orchiectomy, magnetic resonance imaging (MRI) has been recommended because it shows lesion margins optimally ( 33 ). Using ultrasound, testicular abnormalities are noted in 27 ( 43 ) to 94 percent ( 30...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-04
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
...); outer margin of the subcapsular zona glomerulosa Positive with variable intensity c Aldosterone-producing nodule Visible Recognizable on H&E, <10 mm, compact or clear or mixed cell histology; no specific location within the adrenal cortex Positive with variable intensity...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-08
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
...-positive tumor. There is also activity in the retroperitoneum showing recurrent disease around the resection margin of the primary tumor. METASTATIC PHEOCHROMOCYTOMA Figure 8-52 METASTATIC PHEOCHROMOCYTOMA The presence of paraganglioma in lymph node (A) or bone (B) is unequivocal evidence of metastatic...
Images
Figure 6-11
Published: 01 September 2024
and papillary dermal necrosis, leading to bulla formation. The epidermis at the ulcer margins was hyperplastic, and shows ballooning degeneration of basal keratinocytes and scattered multinucleated keratinocytes. F: Rare eosinophilic epithelial cytoplasmic inclusions (arrows) at the margin of the pustule. G More about this image found in MPOX Microscopic features of skin lesions. (Courtesy of the CDC IDPB) A: ...
Images
Figure 6-11
Published: 01 September 2024
and papillary dermal necrosis, leading to bulla formation. The epidermis at the ulcer margins was hyperplastic, and shows ballooning degeneration of basal keratinocytes and scattered multinucleated keratinocytes. F: Rare eosinophilic epithelial cytoplasmic inclusions (arrows) at the margin of the pustule. G More about this image found in MPOX Microscopic features of skin lesions. (Courtesy of the CDC IDPB) A: ...
Images
Images
Figure 9-49
Published: 01 September 2024
DECOY CELLS IN URINE CYTOLOGY SPECIMENS Figure 9-49 DECOY CELLS IN URINE CYTOLOGY SPECIMENS A: Papanicolaou stain shows variation in epithelial nuclear size and characteristic intranuclear inclusions. B: Diff quick stain, with ground-glass nuclear inclusion and peripheral chromatin margination More about this image found in DECOY CELLS IN URINE CYTOLOGY SPECIMENS A: Papanicolaou stain shows variat...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-06
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... with extensive full-thickness epidermal and papillary dermal necrosis, leading to bulla formation. The epidermis at the ulcer margins was hyperplastic, and shows ballooning degeneration of basal keratinocytes and scattered multinucleated keratinocytes. F: Rare eosinophilic epithelial cytoplasmic inclusions...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-03
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... margination) Varicella-zoster (human herpes virus-3) Worldwide Vesicular skin rash: widespread (if varicella) or in a dermatome distribution (if zoster) In children: cerebellar ataxia Necrosis usually hemorrhagic, viral inclusions (like HSV) Cytomegalovirus (CMV) Worldwide Seen in immune-suppressed...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-11
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... in stillbirths, there is usually prominent meconium and fetal hydrops, with a papular rash surrounded by red margins ( 7 ). Numerous organs usually demonstrate multiple small abscesses. Microscopically, Listeria abscesses (which may be single or, more often, multiple) are composed of abundant...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-15
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... ulcer, with raised margins and a red center (“raspberry-like”) Pruritic but not painful There may be satellite and secondary lesions Lesions on the plantar surface result in painful fissures, causing a distinctive “crab yaws” walk or gait Accompanied by lymphadenopathy and arthralgia; persists...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-09
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
...: Diff quick stain, with ground-glass nuclear inclusion and peripheral chromatin margination. (Courtesy of Dr. J. P. Sandoval, University of Antioquia, Medellín, Colombia) DIFFERENTIAL DIAGNOSIS OF HSIL Figure 9-42 DIFFERENTIAL DIAGNOSIS OF HSIL A: Atrophy with reactive atypia and negative p16...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-08
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
..., with margination and beading of the chromatin. The nuclei have a ground-glass appearance and koilocytic changes are present. These nuclear changes are sometimes observed on cytology and histology, even in the absence of gross lesions. EBV infection is associated with the production of heterophile antibodies...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-05
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... clinical course ( fig. 5-3 ). Typical HSV cytopathic effect, including syncytial hepatocytes with nuclear molding, eosinophilic nuclear inclusions, and chromatin margination, are often identified. EBV infection often demonstrates atypical lymphocytes in the sinusoids and portal tracts. Complications...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-04
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
..., chromatin margination, and ground-glass inclusions Cytomegalovirus (human herpes virus 5; see chapter 5 ) Herpesviridae Initial infection with fever, rash, and lymphadenopathy; then becomes dormant Reactivation and systemic dissemination in the immune compromised Pneumonia, gastroenteritis...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-21
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... and blood vessels, leading to localized thrombosis and secondary infarction. There is typically scant inflammation, as this form is usually seen in neutropenic individuals ( fig. 21-30 ). Tissue frozen section is often performed during debridement to define viable tissue at the surgical margin. Chronic...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-12
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... and septicemia Cellulitis Any age Fever, as well as indurated, erythematous and tender skin and soft tissues (usually with indistinct margins) Septicemia and death Chorioamnionitis and other obstetrical infections Woman of reproductive age Premature rupture of membranes, fever, chills, uterine...