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PHEOCHROMOCYTOMA: <sup>68</sup>GA DOTATATE SCAN  Multifocal osteolytic skel...
Published: 01 December 2024
PHEOCHROMOCYTOMA: 68GA DOTATATE SCAN Figure 8-51 PHEOCHROMOCYTOMA: 68GA DOTATATE SCAN Multifocal osteolytic skeletal lesions demonstrate dotatate avidity consistent with a somatostatin receptor-positive tumor. There is also activity in the retroperitoneum showing recurrent disease around the resection margin of the primary tumor. More about this image found in PHEOCHROMOCYTOMA: 68GA DOTATATE SCAN Multifocal osteolytic skel...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-06
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... with the liver) ( 79 ). Table 6-1 IMAGING CHARACTERISTICS OF BENIGN VERSUS MALIGNANT ADRENAL MASSES a Characteristic Likely Benign Suspicious for Malignancy Size Small (<4 cm) Large (>4 cm) Shape Round or oval Irregular Margins Smooth Irregular Texture Homogeneous...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-11
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... be achieved, and resection or debulking is performed following chemotherapy. Such resections frequently arrive piecemeal in the pathology laboratory and resection margins are not an issue with regard to pathology reporting. Instead, the amount of chemotherapy effect should be assessed upon gross morphology...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-02
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... palpation ( 42 , 43 ) and is the most cost-effective and quickest imaging technique. In cases of partial orchiectomy, magnetic resonance imaging (MRI) has been recommended because it shows lesion margins optimally ( 33 ). Using ultrasound, testicular abnormalities are noted in 27 ( 43 ) to 94 percent ( 30...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-04
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
...); outer margin of the subcapsular zona glomerulosa Positive with variable intensity c Aldosterone-producing nodule Visible Recognizable on H&E, <10 mm, compact or clear or mixed cell histology; no specific location within the adrenal cortex Positive with variable intensity...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-08
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
...-positive tumor. There is also activity in the retroperitoneum showing recurrent disease around the resection margin of the primary tumor. METASTATIC PHEOCHROMOCYTOMA Figure 8-52 METASTATIC PHEOCHROMOCYTOMA The presence of paraganglioma in lymph node (A) or bone (B) is unequivocal evidence of metastatic...
Images
MPOX  Microscopic features of skin lesions. (Courtesy of the CDC IDPB)  A: ...
Published: 01 September 2024
MPOX Figure 6-11 MPOX Microscopic features of skin lesions. (Courtesy of the CDC IDPB) A: Early changes showing a lichenoid papillary dermal and perivascular mixed inflammatory cell infiltrate, which includes lymphocytes, macrophages, and rare eosinophils. Single dyskeratotic cells are visible i... More about this image found in MPOX Microscopic features of skin lesions. (Courtesy of the CDC IDPB) A: ...
Images
MPOX  Microscopic features of skin lesions. (Courtesy of the CDC IDPB)  A: ...
Published: 01 September 2024
MPOX Figure 6-11 MPOX Microscopic features of skin lesions. (Courtesy of the CDC IDPB) A: Early changes showing a lichenoid papillary dermal and perivascular mixed inflammatory cell infiltrate, which includes lymphocytes, macrophages, and rare eosinophils. Single dyskeratotic cells are visible i... More about this image found in MPOX Microscopic features of skin lesions. (Courtesy of the CDC IDPB) A: ...
Images
EARLY STAGES OF PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY (PML)  In stereo...
Published: 01 September 2024
EARLY STAGES OF PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY (PML) Figure 3-38 EARLY STAGES OF PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY (PML) In stereotactic brain biopsy, scattered oligodendrocytes with enlarged nuclei containing violaceous inclusions are seen. Virions fill the nucleus and margi... More about this image found in EARLY STAGES OF PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY (PML) In stereo...
Images
DECOY CELLS IN URINE CYTOLOGY SPECIMENS  A: Papanicolaou stain shows variat...
Published: 01 September 2024
DECOY CELLS IN URINE CYTOLOGY SPECIMENS Figure 9-49 DECOY CELLS IN URINE CYTOLOGY SPECIMENS A: Papanicolaou stain shows variation in epithelial nuclear size and characteristic intranuclear inclusions. B: Diff quick stain, with ground-glass nuclear inclusion and peripheral chromatin margination. ... More about this image found in DECOY CELLS IN URINE CYTOLOGY SPECIMENS A: Papanicolaou stain shows variat...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-06
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... with a prominent neutrophil-rich mixed inflammatory cell infiltrate. Many infected epithelial cells fuse to form multinucleated (syncytial) cells with nuclear molding. Characteristic eosinophilic ground-glass intranuclear (Cowdry type-A) viral inclusions lead to margination of the basophilic host chromatin...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-03
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... of the nuclear membrane (chromatin margination). This is seen in both neurons ( fig. 3-25 , inset) and oligodendrocytes ( figs. 3-32 , inset; 3-33 , arrows). Cytoplasmic inclusions do not occur in SSPE. At high power, interspersed reactive astrocytes with eosinophilic cytoplasm and tapering stellate processes...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-11
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... a particular proclivity for infecting placental and brain tissue ( 6 ). In early-onset listeriosis, particularly in stillbirths, there is usually prominent meconium and fetal hydrops, with a papular rash surrounded by red margins ( 7 ). Numerous organs usually demonstrate multiple small abscesses...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-15
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... debridement to remove all necrotic tissue is indispensable in successfully treating necrotizing fasciitis ( 8 ). The surgical goal is to leave viable tissue margins, which usually requires more than one surgical debridement and frequently leaves large wounds. Antibiotics should be administered as soon...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-09
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... of nuclear inclusions. The most characteristic is amorphous and basophilic, with margination of host chromatin. Other types include a granular eosinophilic nuclear inclusion, with or without a partial halo, as well as enlarged nuclei with prominent nucleoli and clumped chromatin. The inclusions lead...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-08
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
..., with margination and beading of the chromatin. The nuclei have a ground-glass appearance and koilocytic changes are present. These nuclear changes are sometimes observed on cytology and histology, even in the absence of gross lesions. ORAL HAIRY LEUKOPLAKIA Figure 8-10 ORAL HAIRY LEUKOPLAKIA Prominent squamous...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-05
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... margination, are often identified. EBV infection often demonstrates atypical lymphocytes in the sinusoids and portal tracts. Complications of acute viral hepatitis include acute hepatic failure, postinfection scarring, and persistent disease as a chronic carrier or chronic hepatitis. ACUTE VIRAL HEPATITIS DUE...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-04
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
..., chromatin margination, and ground-glass inclusions Cytomegalovirus (human herpes virus 5; see chapter 5 ) Herpesviridae Initial infection with fever, rash, and lymphadenopathy; then becomes dormant Reactivation and systemic dissemination in the immune compromised Pneumonia, gastroenteritis...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-21
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... tissue at the surgical margin. Chronic granulomatous fungal rhinosinusitis is a chronic form of this infection described in India and the Middle East. It typically has a disease duration of more than 12 weeks and microscopically demonstrates mucosal and submucosal granulomatous inflammation...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-12
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... Fever, as well as indurated, erythematous and tender skin and soft tissues (usually with indistinct margins) Septicemia and death Chorioamnionitis and other obstetrical infections Woman of reproductive age Premature rupture of membranes, fever, chills, uterine tenderness, maternal and fetal...