1-20 of 306 Search Results for

margin

Follow your search
Access your saved searches in your account

Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Images
INFILTRATING <span class="search-highlight">MARGIN</span>  A: H&amp;E stain of a grade 1 invasive breast carcinom...
Published: 01 January 2024
INFILTRATING MARGIN Figure 8-14 INFILTRATING MARGIN A: H&E stain of a grade 1 invasive breast carcinoma, NST. The infiltrative margin is a helpful clue to the malignant nature of a proliferation composed of small glands. B: In problematic cases, myoepithelial cell markers, such as p63, are h... More about this image found in INFILTRATING MARGIN A: H&E stain of a grade 1 invasive breast carcinom...
Images
PUSHING <span class="search-highlight">MARGIN</span>  Some carcinomas, particularly grade 3, triple-negative tumo...
Published: 01 January 2024
PUSHING MARGIN Figure 8-15 PUSHING MARGIN Some carcinomas, particularly grade 3, triple-negative tumors are characterized by a more circumscribed or “pushing” margin. More about this image found in PUSHING MARGIN Some carcinomas, particularly grade 3, triple-negative tumo...
Images
NIPPLE <span class="search-highlight">MARGIN</span>  This low-power image illustrates a shaved, en face section o...
Published: 01 January 2024
NIPPLE MARGIN Figure 15-11 NIPPLE MARGIN This low-power image illustrates a shaved, en face section of the nipple margin. This orientation permits examination of a cross-section of the nipple ducts. More about this image found in NIPPLE MARGIN This low-power image illustrates a shaved, en face section o...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-23
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
... with an increased risk for local recurrence, particularly if the surgical margins are positive or narrow ( 10 ). In such instances, radiotherapy may reduce the incidence of local recurrence. Regression. Regression refers to observations that the body’s immune system can attack and destroy tumor. Histologic...
Images
EXCISION OF MELANOMA IN SITU  A: A rim of normal skin is between the edge o...
Published: 01 February 2024
EXCISION OF MELANOMA IN SITU Figure 13-15 EXCISION OF MELANOMA IN SITU A: A rim of normal skin is between the edge of the melanoma in situ and the inked side margin (H&E stain). B: Immunostain for PRAME. C: The junctional melanoma cells display nuclear labeling for PRAME. More about this image found in EXCISION OF MELANOMA IN SITU A: A rim of normal skin is between the edge o...
Images
NEST OF LENTIGO MALIGNA VERSUS INFLAMMATORY PSEUDONEST  A: A junctional nes...
Published: 01 February 2024
NEST OF LENTIGO MALIGNA VERSUS INFLAMMATORY PSEUDONEST Figure 13-10 NEST OF LENTIGO MALIGNA VERSUS INFLAMMATORY PSEUDONEST A: A junctional nest of melanocytes is seen in a margin section from a lentigo maligna melanoma (LMM) in situ. B: This lichenoid inflammatory pseudonest is composed of a clu... More about this image found in NEST OF LENTIGO MALIGNA VERSUS INFLAMMATORY PSEUDONEST A: A junctional nes...
Images
EXTRANODAL <span class="search-highlight">MARGINAL</span> ZONE LYMPHOMA OF MUCOSA-ASSOCIATED LYMPHOID TISSUE (MAL...
Published: 01 January 2024
EXTRANODAL MARGINAL ZONE LYMPHOMA OF MUCOSA-ASSOCIATED LYMPHOID TISSUE (MALT LYMPHOMA) Figure 12-4 EXTRANODAL MARGINAL ZONE LYMPHOMA OF MUCOSA-ASSOCIATED LYMPHOID TISSUE (MALT LYMPHOMA) Low- (A), intermediate- (B), and high- (C) power images of MALT lymphoma arising in the breast. More about this image found in EXTRANODAL MARGINAL ZONE LYMPHOMA OF MUCOSA-ASSOCIATED LYMPHOID TISSUE (MAL...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-13
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
... of melanocytes is seen in a margin section from a lentigo maligna melanoma (LMM) in situ. B: This lichenoid inflammatory pseudonest is composed of a cluster of lymphocytes and dyscohesive keratinocytes. Lentigo Maligna Melanoma (LMM) Most LMMs are thin tumors, with only a few isolated tumor cells ( fig. 13-11...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-16
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
.... This is in large part related to anatomic site-related limitations in margin clearance and perineural invasion, but historically probably also to the difficulty of margin assessment and false-negative readings by pathologists. Since the tumors commonly occur in the head and neck region, options for wide and deep...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 18
Published: 01 January 2024
10.55418/9781933477367-15
ISBN-10: 1-933477-36-9
ISBN: 978-1-933477-36-7
... in six colors, corresponding to the anterior/superficial, posterior/deep, medial, lateral, superior, and inferior margins ( fig. 15-6 ); unoriented specimens should still be inked (in a single color) in the event an unexpected malignancy is identified. A typical “key” used by surgeons is for a short...
Images
INK TRACKING  Ink readily tracks into the crevices of breast specimens. Ext...
Published: 01 January 2024
INK TRACKING Figure 15-7 INK TRACKING Ink readily tracks into the crevices of breast specimens. Extra care is required to prevent this occurrence, which is particularly problematic if there is a tumor close to the specimen margin. More about this image found in INK TRACKING Ink readily tracks into the crevices of breast specimens. Ext...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-09
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
.... While melanoma can simulate a DPN, we are not aware of a case of melanoma that has arisen at the site of or in association with an incompletely removed DPN. Thus, if a DPN has been diagnosed correctly and lacks atypical features, focal extension of the lesion to a biopsy margin does not require further...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-11
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
... tumor. The risk for progression to melanoma is not known, but is probably low. Nonetheless, it is generally considered good practice to excise lesions of PEM with a negative margin. Similar to Spitz nevi/tumors and blue or deep penetrating nevi, deposits of melanocytes may be found in regional lymph...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-15
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
... melanoma. The odds for recurrent melanoma are much higher. Then more information about the primary tumor is needed. Where was the prior melanoma located? Did it have high-risk features? How many years ago was it removed? Was it removed with clear negative margins? Did it look similar? Answers to those...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-12
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
... ), and ulceration. The peripheral margins of SMM can be ill-defined or sharply demarcated. The tumor cells of SSM typically display cytologic atypia. They may have large epithelioid nuclei, hyperchromasia, or a vesicular chromatin pattern with prominent, sometimes eosinophilic nucleoli. The cytoplasm...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-08
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
... well-circumscribed with regular borders   Size usually 0.3 to 3 cm Histopathologic Findings  Symmetry  Localization to reticular dermis  Often deep extension with bulging, nodular configuration, rounded, well-demarcated inferior margin  Heterogeneity of patterns   biphasic...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 18
Published: 01 January 2024
10.55418/9781933477367-05
ISBN-10: 1-933477-36-9
ISBN: 978-1-933477-36-7
...) and the area of greatest stromal cellularity with a benign epithelial element (C). Phyllodes tumors are treated with surgical resection. Debate remains as to the required margin width for an adequate resection, with over 10 mm often being cited in the past ( 33 ) and still being recommended by the National...
Images
VENTRICULAR <span class="search-highlight">MARGINS</span>  The two sides of the right ventricular free wall form ...
Published: 15 November 2023
VENTRICULAR MARGINS Figure 1-15 VENTRICULAR MARGINS The two sides of the right ventricular free wall form an acute angle that represents a well-defined acute margin (yellow arrow). Opposite this, however, the left ventricular free wall is rounded, such that tangential lines form an obtuse angle, ... More about this image found in VENTRICULAR MARGINS The two sides of the right ventricular free wall form ...
Images
CARDIAC FIBROMA: <span class="search-highlight">MARGINS</span>  The periphery of cardiac fibromas frequently show...
Published: 15 November 2023
CARDIAC FIBROMA: MARGINS Figure 42-6 CARDIAC FIBROMA: MARGINS The periphery of cardiac fibromas frequently show tumor extending into adjacent myocardium, seen with hematoxylin and eosin (left) or better highlighted with Masson trichrome staining (right). More about this image found in CARDIAC FIBROMA: MARGINS The periphery of cardiac fibromas frequently show...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 18
Published: 01 January 2024
10.55418/9781933477367-04
ISBN-10: 1-933477-36-9
ISBN: 978-1-933477-36-7
... is required. Evaluation of the proximity of classic LCIS to the margins is not indicated. Chemoprevention with selective estrogen receptor (ER) modulators (SERMs) or an aromatase inhibitor (AI) may be offered to reduce the subsequent breast cancer risk. The reduction in risk is substantial (about 50 percent...