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Figure 6-66
Published: 01 June 2025
LYMPHOEPITHELIAL CARCINOMA Figure 6-66 LYMPHOEPITHELIAL CARCINOMA A,B: The biopsy shows a high nuclear to cytoplasmic ratio, malignant epithelioid cells with vesicular nuclei, and distinct nucleoli with a surrounding lymphoplasmacytic infiltrate. C: Malignant cells are positive for CK5/6. More about this image found in LYMPHOEPITHELIAL CARCINOMA A,B: The biopsy shows a high nuclear to cytopla...
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Figure 2-17
Published: 01 June 2025
LYMPHOEPITHELIAL (OR UNDIFFERENTIATED) CARCINOMA Figure 2-17 LYMPHOEPITHELIAL (OR UNDIFFERENTIATED) CARCINOMA This resembles nasopharyngeal carcinoma with poorly defined nests of tumor cells in a dense lymphocytic or mixed lymphoplasmacytic background. Cells have ill-defined cell borders More about this image found in LYMPHOEPITHELIAL (OR UNDIFFERENTIATED) CARCINOMA This resembles nasopharyn...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 22
Published: 01 June 2025
10.55418/9781933477619-2
ISBN: 978-1-933477-61-9
... from the same tumor of the nasopharynx. It consists of poorly defined nests and sheets of tumor cells with ill-defined cell borders, round nuclei with vesicular chromatin and prominent nucleoli, and a dense lymphoplasmacytic inflammatory infiltrate ( fig. 2-17 ). Despite the similarities...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 22
Published: 01 June 2025
10.55418/9781933477619-6
ISBN: 978-1-933477-61-9
... lymphoplasmacytic component histologically resembling nonkeratinizing nasopharyngeal carcinoma (see chapter 3 [Nasopharynx] for information about nasopharyngeal carcinoma). General Features. Lymphoepithelial carcinoma occurs in several head and neck sites: the larynx (where it is very rare), oropharynx, trachea...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 22
Published: 01 June 2025
10.55418/9781933477619-1
ISBN: 978-1-933477-61-9
... secretions. There is no mitotic activity or cellular atypia. The background stroma resembles an inflammatory polyp, with edema and a mild lymphoplasmacytic infiltrate. REAH-like elements, consisting of glands or cysts lined by ciliated respiratory epithelium, can be present, and hybrid lesions with features...
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Figure 8-18
Published: 01 December 2024
PHEOCHROMOCYTOMA: FOCAL CHRONIC INFLAMMATION Figure 8-18 PHEOCHROMOCYTOMA: FOCAL CHRONIC INFLAMMATION In occasional pheochromocytomas there is a focal lymphoplasmacytic infiltrate. More about this image found in PHEOCHROMOCYTOMA: FOCAL CHRONIC INFLAMMATION In occasional pheochromocytom...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-03
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... systems. In the autoimmune polyglandular forms, the disease is initially characterized by a chronic lymphoplasmacytic infiltrate of the adrenal glands; this progresses to fibrosis and atrophy and may result in near total loss of the adrenal cortex, leaving only a rim of fibrous tissue around the medulla...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-08
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... and numerous small blood vessels. Amyloid has been reported ( 38 – 40 ) but is rare ( 40 ). PHEOCHROMOCYTOMA: FOCAL CHRONIC INFLAMMATION Figure 8-18 PHEOCHROMOCYTOMA: FOCAL CHRONIC INFLAMMATION In occasional pheochromocytomas there is a focal lymphoplasmacytic infiltrate. PHEOCHROMOCYTOMA ASSOCIATED...
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Figure 18-2
Published: 01 September 2024
PRIMARY SYPHILIS Figure 18-2 PRIMARY SYPHILIS Typical endothelial cell swelling and proliferation are associated with a lymphoplasmacytic perivascular infiltrate and interspersed neutrophils. More about this image found in PRIMARY SYPHILIS Typical endothelial cell swelling and proliferation are a...
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Figure 13-30
Published: 01 September 2024
CHRONIC H. PYLORI-ASSOCIATED GASTRITIS Figure 13-30 CHRONIC H. PYLORI-ASSOCIATED GASTRITIS A prominent lymphoplasmacytic mucosal infiltrate and interspersed secondary lymphoid follicles with germinal centers are present. More about this image found in CHRONIC H. PYLORI-ASSOCIATED GASTRITIS A prominent lympho...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-18
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... and proliferation are associated with a lymphoplasmacytic perivascular infiltrate and interspersed neutrophils. SYPHILIS Figure 18-3 SYPHILIS Pronounced and deep plasma cell infiltration. SECONDARY SYPHILIS OF SKIN Figure 18-6 SECONDARY SYPHILIS OF SKIN Lichenoid inflammation with prominent plasma cells...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-22
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... reveals an abundance of organism spores, which may be associated with cellular degeneration and prominent necrosis. An associated inflammatory response may, however, be absent. If present, it often consists of a mixed cellular infiltrate ranging from lymphoplasmacytic (sometimes with eosinophils...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-15
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... eating extremely difficult. The initial hallmark pathologic feature of endemic treponematoses is a prominent lymphoplasmacytic perivascular inflammatory cell infiltrate accompanied by abundant spirochetes ( fig. 15-37A–C ) ( 48 , 52 ). This inflammatory response evolves to become a dense dermal...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-28
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... granulomas with Langhans-type giant cells and a surrounding lymphoplasmacytic cuff develop, with giant cells showing microscopically identifiable intracytoplasmic parasites ( fig. 28-6 ). Large numbers of plasma cells are typical of late skin lesions. For skin disease, a directed punch or excisional biopsy...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-26
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
.... Often there are only mild and nonspecific changes, such as mild villous blunting, mucosal lymphoplasmacytic inflammatory cell increase, and surface epithelial disarray, degeneration, and reactive change ( figs. 26-24 , 26-25 ). Prominent crypt hyperplasia, mucosal infiltration by neutrophils...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-12
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... also shorten the duration of antibiotic treatment ( 62 ). Lung pathology in M. pneumoniae infection is characterized by lymphocytic, lymphoplasmacytic, or neutrophilic inflammation centered around bronchioles and often involving the alveolar wall ( 70 ). There may be necrosis and sloughing...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-14
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
.... Pericarditis can also be present. Histopathology of the heart lesions includes collections of mononuclear inflammatory cells with occasional non-necrotizing granulomas. Neurobrucellosis may show meningeal infiltration by a lymphoplasmacytic infiltrate. Special bacterial silver (such as Warthin-Starry...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-13
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
...: MAC bacilli, however, show weaker PAS staining (B) and are acid fast (C, Ziehl-Neelsen stain). CHRONIC H. PYLORI-ASSOCIATED GASTRITIS Figure 13-30 CHRONIC H. PYLORI-ASSOCIATED GASTRITIS A prominent lymphoplasmacytic mucosal infiltrate and interspersed secondary lymphoid follicles...
Images
Figure 8-9
Published: 01 January 2024
TUMOR-INFILTRATING LYMPHOCYTES Figure 8-9 TUMOR-INFILTRATING LYMPHOCYTES Some tumors are characterized by a brisk lymphoplasmacytic infiltrate in the intratumoral stroma. More about this image found in TUMOR-INFILTRATING LYMPHOCYTES Some tumors are characterized by a brisk ly...
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