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lymphoma
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Images
Published: 15 November 2023
PRIMARY CARDIAC LYMPHOMA: MYOCARDIAL INVOLVEMENT Figure 57-6 PRIMARY CARDIAC LYMPHOMA: MYOCARDIAL INVOLVEMENT Left: Lymphoma cells infiltrate the interstitium and incite myocyte injury, characterized by contraction bands that closely mimic myocarditis. Unlike myocarditis, the infiltrate is primar... More about this image found in PRIMARY CARDIAC LYMPHOMA: MYOCARDIAL INVOLVEMENT Left: Lymphoma cells infi...
Images
Published: 15 November 2023
PRIMARY CARDIAC LYMPHOMA Figure 57-7 PRIMARY CARDIAC LYMPHOMA The cells of diffuse large B-cell lymphoma (DLBCL) are large and resemble immunoblasts, with amphophilic cytoplasm, eccentric nuclei, and focally prominent nucleoli. More about this image found in PRIMARY CARDIAC LYMPHOMA The cells of diffuse large B-cell lymphoma (DLBCL...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch57
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
...PRIMARY CARDIAC LYMPHOMA: IMAGING FEATURES Figure 57-1 PRIMARY CARDIAC LYMPHOMA: IMAGING FEATURES The tumor manifests as an enhancing mass (yellow arrowhead) on the epicardial surface between the right and left ventricles (RV and LV, respectively). PRIMARY CARDIAC LYMPHOMA Figure 57-2 PRIMARY...
Images
Published: 15 November 2023
PRIMARY CARDIAC LYMPHOMA: EPICARDIAL INVOLVEMENT Figure 57-5 PRIMARY CARDIAC LYMPHOMA: EPICARDIAL INVOLVEMENT The epicardium is extensively involved by lymphoma, which focally extends into the subjacent myocardium, primarily along the vasculature. More about this image found in PRIMARY CARDIAC LYMPHOMA: EPICARDIAL INVOLVEMENT The epicardium is extensi...
Images
Published: 15 November 2023
PRIMARY CARDIAC LYMPHOMA: ENDOCARDIAL INVOLVEMENT Figure 57-4 PRIMARY CARDIAC LYMPHOMA: ENDOCARDIAL INVOLVEMENT Left: Patchy endocardial thickening (yellow arrows) is seen grossly. Right: Histologically, there is dense endocardial infiltration by primary cardiac lymphoma. More about this image found in PRIMARY CARDIAC LYMPHOMA: ENDOCARDIAL INVOLVEMENT Left: Patchy endocardial...
Images
Published: 15 November 2023
PRIMARY CARDIAC LYMPHOMA: IMAGING FEATURES Figure 57-1 PRIMARY CARDIAC LYMPHOMA: IMAGING FEATURES The tumor manifests as an enhancing mass (yellow arrowhead) on the epicardial surface between the right and left ventricles (RV and LV, respectively). More about this image found in PRIMARY CARDIAC LYMPHOMA: IMAGING FEATURES The tumor manifests as an enhan...
Images
Published: 15 November 2023
PRIMARY CARDIAC LYMPHOMA Figure 57-2 PRIMARY CARDIAC LYMPHOMA Left: A subtle mass (black asterisk) is noted in the atrial septum, without encroachment on either the right or left atria (RA and LA, respectively). The right and left ventricles (RV and LV, respectively) are uninvolved. Right: The L... More about this image found in PRIMARY CARDIAC LYMPHOMA Left: A subtle mass (black asterisk) is noted in ...
Images
Published: 15 November 2023
PRIMARY CARDIAC LYMPHOMA Figure 57-3 PRIMARY CARDIAC LYMPHOMA The tumor (black asterisk) is tracking along the left atrioventricular groove, and encroaching upon the left circumflex artery (yellow arrow) and the coronary sinus (black arrowhead). More about this image found in PRIMARY CARDIAC LYMPHOMA The tumor (black asterisk) is tracking along the ...
Images
Published: 15 November 2023
PRIMARY CARDIAC LYMPHOMA Figure 57-8 PRIMARY CARDIAC LYMPHOMA On biopsy, DLBCL manifests as a small round blue cell neoplasm and can have extensive crush artifact. Immunohistochemistry is necessary for definitive interpretation. More about this image found in PRIMARY CARDIAC LYMPHOMA On biopsy, DLBCL manifests as a small round blue ...
Images
Published: 15 November 2023
PRIMARY CARDIAC LYMPHOMA: IMMUNOHISTOCHEMISTRY Figure 57-9 PRIMARY CARDIAC LYMPHOMA: IMMUNOHISTOCHEMISTRY The neoplastic cells of DLBCL typically exhibit the following immunoprofile: CD20 positive (A); CD3 negative (B); BCL6 positive (C); and MUM1 positive (D). More about this image found in PRIMARY CARDIAC LYMPHOMA: IMMUNOHISTOCHEMISTRY The neoplastic cells of DLB...
Images
Published: 15 November 2023
FIBRIN-ASSOCIATED DIFFUSE LARGE B-CELL LYMPHOMA Figure 57-10 FIBRIN-ASSOCIATED DIFFUSE LARGE B-CELL LYMPHOMA Left: The lesional cells may be subtle, usually only a minor component of an abundant fibrinous exudate. Right: The lesion cells are large and somewhat atypical, but the dense cellularity... More about this image found in FIBRIN-ASSOCIATED DIFFUSE LARGE B-CELL LYMPHOMA Left: The lesional cells m...
Images
Published: 15 November 2023
FIBRIN-ASSOCIATED DIFFUSE LARGE B-CELL LYMPHOMA: EPSTEIN-BARR VIRUS (EBV) POSITIVITY Figure 57-11 FIBRIN-ASSOCIATED DIFFUSE LARGE B-CELL LYMPHOMA: EPSTEIN-BARR VIRUS (EBV) POSITIVITY The lesional cells are EBV positive on in situ hybridization for EBER. More about this image found in FIBRIN-ASSOCIATED DIFFUSE LARGE B-CELL LYMPHOMA: EPSTEIN-BARR VIRUS (EBV) P...
Images
Published: 15 November 2023
RADIATION VASCULOPATHY Figure 6-23 RADIATION VASCULOPATHY Significant atherosclerosis is seen in this young woman in her third decade, 10 years after therapy for lymphoma in the thorax. The degree of narrowing is far out of proportion for what would be expected for a woman of her age. More about this image found in RADIATION VASCULOPATHY Significant atherosclerosis is seen in this young w...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch52
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... , Saraiva TB , Arruda MB , Lira V . Cardiac extension of primary mediastinal seminoma compressing the right ventricular outflow tract . Arq Bras Cardiol 2001 ; 76 : 149 - 54 . 67. Roberts WC , Glancy DL , DeVita VT Jr . Heart in malignant lymphoma (Hodgkin’s...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch41
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... JS , Berrutti L . Cardiac myxoma immunohistochemistry: value of CD34, CD31, and factor XIIIa staining . Diagn Cytopathol 1996 ; 15 : 455 - 6 . 80. Liu X , Liu P , Li J . EBV+ diffuse large B-cell lymphoma arising within atrial myxoma in Chinese immunocompetent...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch50
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... expressed desmin ( 15 ). Variable expression may also be seen with calponin and muscle-specific antigen (MSA). No published case of cardiac IMT has documented definitive immunohistochemical evidence of anaplastic lymphoma kinase 1 (ALK-1) expression ( 8 ). One tumor was tested for ALK-1 gene...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch06
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... decade, 10 years after therapy for lymphoma in the thorax. The degree of narrowing is far out of proportion for what would be expected for a woman of her age. AMYLOID ANGIOPATHY Figure 6-24 AMYLOID ANGIOPATHY Amyloid typically does not affect the epicardial coronary arteries, but when it does...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch33
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
..., followed by catheter-induced thrombosis and sclerosing mediastinitis, which represent the majority of the remainder ( 37 , 38 ). Approximately 78 to 85 percent of malignant superior vena cava obstructions occur secondary to lung cancer, especially small cell carcinoma, followed by lymphoma and a variety...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch27
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... ). Metastases from carcinomas of the lung, breast, and stomach are common. Lymphoma may spread from the mediastinum or seed the pericardium causing constriction. Of the primary cardiac neoplasms, only angiosarcoma may cause bloody effusions. It commonly involves the right side of the heart and often invades...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch24
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... lymphoproliferative disorder (PTLD) is a wide spectrum of lymphoproliferative conditions, ranging from hyperplasia to lymphoma, that develops in the post-transplant setting. PTLD is usually driven by underlying infection with the Epstein-Barr virus (EBV), particularly when it occurs within 5 years of transplant. Late...
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