PRIMARY CARDIAC LYMPHOMA: MYOCARDIAL INVOLVEMENT Figure 57-6 PRIMARY CARDIAC LYMPHOMA: MYOCARDIAL INVOLVEMENT Left: Lymphoma cells infiltrate the interstitium and incite myocyte injury, characterized by contraction bands that closely mimic myocarditis. Unlike myocarditis, the infiltrate is primar... More about this image found in PRIMARY CARDIAC LYMPHOMA: MYOCARDIAL INVOLVEMENT Left: Lymphoma cells infi...

PRIMARY CARDIAC LYMPHOMA Figure 57-7 PRIMARY CARDIAC LYMPHOMA The cells of diffuse large B-cell lymphoma (DLBCL) are large and resemble immunoblasts, with amphophilic cytoplasm, eccentric nuclei, and focally prominent nucleoli. More about this image found in PRIMARY CARDIAC LYMPHOMA The cells of diffuse large B-cell lymphoma (DLBCL...

PRIMARY CARDIAC LYMPHOMA: EPICARDIAL INVOLVEMENT Figure 57-5 PRIMARY CARDIAC LYMPHOMA: EPICARDIAL INVOLVEMENT The epicardium is extensively involved by lymphoma, which focally extends into the subjacent myocardium, primarily along the vasculature. More about this image found in PRIMARY CARDIAC LYMPHOMA: EPICARDIAL INVOLVEMENT The epicardium is extensi...

PRIMARY CARDIAC LYMPHOMA: ENDOCARDIAL INVOLVEMENT Figure 57-4 PRIMARY CARDIAC LYMPHOMA: ENDOCARDIAL INVOLVEMENT Left: Patchy endocardial thickening (yellow arrows) is seen grossly. Right: Histologically, there is dense endocardial infiltration by primary cardiac lymphoma. More about this image found in PRIMARY CARDIAC LYMPHOMA: ENDOCARDIAL INVOLVEMENT Left: Patchy endocardial...

PRIMARY CARDIAC LYMPHOMA: IMAGING FEATURES Figure 57-1 PRIMARY CARDIAC LYMPHOMA: IMAGING FEATURES The tumor manifests as an enhancing mass (yellow arrowhead) on the epicardial surface between the right and left ventricles (RV and LV, respectively). More about this image found in PRIMARY CARDIAC LYMPHOMA: IMAGING FEATURES The tumor manifests as an enhan...

PRIMARY CARDIAC LYMPHOMA Figure 57-2 PRIMARY CARDIAC LYMPHOMA Left: A subtle mass (black asterisk) is noted in the atrial septum, without encroachment on either the right or left atria (RA and LA, respectively). The right and left ventricles (RV and LV, respectively) are uninvolved. Right: The L... More about this image found in PRIMARY CARDIAC LYMPHOMA Left: A subtle mass (black asterisk) is noted in ...

PRIMARY CARDIAC LYMPHOMA Figure 57-3 PRIMARY CARDIAC LYMPHOMA The tumor (black asterisk) is tracking along the left atrioventricular groove, and encroaching upon the left circumflex artery (yellow arrow) and the coronary sinus (black arrowhead). More about this image found in PRIMARY CARDIAC LYMPHOMA The tumor (black asterisk) is tracking along the ...

PRIMARY CARDIAC LYMPHOMA Figure 57-8 PRIMARY CARDIAC LYMPHOMA On biopsy, DLBCL manifests as a small round blue cell neoplasm and can have extensive crush artifact. Immunohistochemistry is necessary for definitive interpretation. More about this image found in PRIMARY CARDIAC LYMPHOMA On biopsy, DLBCL manifests as a small round blue ...

PRIMARY CARDIAC LYMPHOMA: IMMUNOHISTOCHEMISTRY Figure 57-9 PRIMARY CARDIAC LYMPHOMA: IMMUNOHISTOCHEMISTRY The neoplastic cells of DLBCL typically exhibit the following immunoprofile: CD20 positive (A); CD3 negative (B); BCL6 positive (C); and MUM1 positive (D). More about this image found in PRIMARY CARDIAC LYMPHOMA: IMMUNOHISTOCHEMISTRY The neoplastic cells of DLB...

FIBRIN-ASSOCIATED DIFFUSE LARGE B-CELL LYMPHOMA Figure 57-10 FIBRIN-ASSOCIATED DIFFUSE LARGE B-CELL LYMPHOMA Left: The lesional cells may be subtle, usually only a minor component of an abundant fibrinous exudate. Right: The lesion cells are large and somewhat atypical, but the dense cellularity... More about this image found in FIBRIN-ASSOCIATED DIFFUSE LARGE B-CELL LYMPHOMA Left: The lesional cells m...

FIBRIN-ASSOCIATED DIFFUSE LARGE B-CELL LYMPHOMA: EPSTEIN-BARR VIRUS (EBV) POSITIVITY Figure 57-11 FIBRIN-ASSOCIATED DIFFUSE LARGE B-CELL LYMPHOMA: EPSTEIN-BARR VIRUS (EBV) POSITIVITY The lesional cells are EBV positive on in situ hybridization for EBER. More about this image found in FIBRIN-ASSOCIATED DIFFUSE LARGE B-CELL LYMPHOMA: EPSTEIN-BARR VIRUS (EBV) P...

RADIATION VASCULOPATHY Figure 6-23 RADIATION VASCULOPATHY Significant atherosclerosis is seen in this young woman in her third decade, 10 years after therapy for lymphoma in the thorax. The degree of narrowing is far out of proportion for what would be expected for a woman of her age. More about this image found in RADIATION VASCULOPATHY Significant atherosclerosis is seen in this young w...