ULTRASTRUCTURAL CORRELATES OF CORTICAL ZONATION Figure 1-47 ULTRASTRUCTURAL CORRELATES OF CORTICAL ZONATION At low magnification, cells of the zona glomerulosa (A) contain sparse lipid and have round to oval mitochondria with lamellar cristae. Cells of the zona fasciculata (B) contain many large ... More about this image found in ULTRASTRUCTURAL CORRELATES OF CORTICAL ZONATION At low magnification, cell...

NORMAL ABDOMINAL PARAGANGLION Figure 9-5 NORMAL ABDOMINAL PARAGANGLION A: Low magnification shows proximity of this paraganglion to adjacent developing ganglia, adrenal gland, and kidney in a mid-second trimester fetus. B: Higher magnification of paraganglion in a mid-second trimester fetus. Thi... More about this image found in NORMAL ABDOMINAL PARAGANGLION A: Low magnification shows proximity of this...

ADRENAL HEMORRHAGE IN WATERHOUSE-FRIDERICHSEN SYNDROME Figure 12-22 ADRENAL HEMORRHAGE IN WATERHOUSE-FRIDERICHSEN SYNDROME A: Low magnification image of a fresh hematoma. B: Hemorrhagic necrosis of overlying adrenal cortex. More about this image found in ADRENAL HEMORRHAGE IN WATERHOUSE-FRIDERICHSEN SYNDROME A: Low magnificatio...

PRIMARY BILATERAL MACRONODULAR ADRENOCORTICAL DISEASE ASSOCIATED WITH CORTISOL OVERSECRETION Figure 4-33 PRIMARY BILATERAL MACRONODULAR ADRENOCORTICAL DISEASE ASSOCIATED WITH CORTISOL OVERSECRETION Low Ki-67 index (hot spot area). More about this image found in PRIMARY BILATERAL MACRONODULAR ADRENOCORTICAL DISEASE ASSOCIATED WITH CORTI...

MAGNETIC RESONANCE IMAGING (MRI) Figure 8-2 MAGNETIC RESONANCE IMAGING (MRI) A: T1-weighted MRI of the abdomen shows a rounded pheochromocytoma on the right side with a low signal intensity. B: Tumor shows enhancement with gadolinium. More about this image found in MAGNETIC RESONANCE IMAGING (MRI) A: T1-weighted MRI of the abdomen shows a...

“BLACK” ADRENAL CORTICAL ADENOMA IN CUSHING SYNDROME Figure 5-44 “BLACK” ADRENAL CORTICAL ADENOMA IN CUSHING SYNDROME Tumor cells express steroidogenic factor 1 (SF1, A), Melan-A (red, B), and a low Ki-67 labeling index (red, C). More about this image found in “BLACK” ADRENAL CORTICAL ADENOMA IN CUSHING SYNDROME Tumor cells express s...

PEDIATRIC ADRENAL CORTICAL TUMOR: BENIGN Figure 6-41 PEDIATRIC ADRENAL CORTICAL TUMOR: BENIGN A–C: The tumor is shown at progressively higher magnification. It lacks necrosis and signs of invasion and showed low mitotic and proliferation indexes. Final Wieneke score was 0. (Same case as fig. 6-4... More about this image found in PEDIATRIC ADRENAL CORTICAL TUMOR: BENIGN A–C: The tumor is shown at progre...

PRIMARY BILATERAL MACRONODULAR ADRENOCORTICAL DISEASE ASSOCIATED WITH CORTISOL OVERSECRETION Figure 4-19 PRIMARY BILATERAL MACRONODULAR ADRENOCORTICAL DISEASE ASSOCIATED WITH CORTISOL OVERSECRETION The adrenal medulla is compressed by the cortex. A and B show low and high magnifications of the sa... More about this image found in PRIMARY BILATERAL MACRONODULAR ADRENOCORTICAL DISEASE ASSOCIATED WITH CORTI...

SPORADIC ADRENAL CORTICAL DISEASE Figure 4-9 SPORADIC ADRENAL CORTICAL DISEASE Nodular enlargement of the adrenal gland (less than 1 cm) incidentally found in a patient with a large renal cyst. Clear cell features are predominant. A and B show low and high magnifications of the same area, illustr... More about this image found in SPORADIC ADRENAL CORTICAL DISEASE Nodular enlargement of the adrenal gland...

ANCILLARY STAINING IN THE DIFFERENTIAL DIAGNOSIS OF ADRENAL CORTICAL ADENOMA AND CARCINOMA Figure 5-31 ANCILLARY STAINING IN THE DIFFERENTIAL DIAGNOSIS OF ADRENAL CORTICAL ADENOMA AND CARCINOMA A diagnosis of adrenal cortical carcinoma was suspected because of the presence of predominant oncocyti... More about this image found in ANCILLARY STAINING IN THE DIFFERENTIAL DIAGNOSIS OF ADRENAL CORTICAL ADENOM...

SPORADIC ADRENAL CORTICAL DISEASE Figure 4-10 SPORADIC ADRENAL CORTICAL DISEASE Nodular enlargement of the adrenal gland (less than 1 cm) with predominant oncocytic features and diffuse and intense Melan-A positivity (C) (same cases as in fig. 4-2 ). Oncocytic features are responsible for the at... More about this image found in SPORADIC ADRENAL CORTICAL DISEASE Nodular enlargement of the adrenal gland...

PULMONARY PARAGANGLIOMA Figure 9-32 PULMONARY PARAGANGLIOMA A: This paraganglioma was a solitary lesion initially interpreted as an epithelial pulmonary NET. The patient was found to have a hereditary SDHC mutation. No other primary tumors were found and this tumor contained abundant sustentacular cells. In view of the clinical and histologic findings and the low metastasis frequency associated with SDHC mutation, the tumor was consistent with a primary pulmonary paraganglioma. B: High magnification shows nested architecture and cells of varied sizes. C: S-100 protein highlights sustentacular cells. More about this image found in PULMONARY PARAGANGLIOMA A: This paraganglioma was a solitary lesion initia...