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lobule

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PLEOMORPHIC LOBULAR CARCINOMA IN SITU AND MICROINVASIVE CARCINOMA  A <span class="search-highlight">lobule</span>...
Published: 01 January 2024
PLEOMORPHIC LOBULAR CARCINOMA IN SITU AND MICROINVASIVE CARCINOMA Figure 4-18 PLEOMORPHIC LOBULAR CARCINOMA IN SITU AND MICROINVASIVE CARCINOMA A lobule is expanded by atypical, dyshesive epithelial cells with large pleomorphic nuclei. Present in the stroma adjacent to this focus are several scat... More about this image found in PLEOMORPHIC LOBULAR CARCINOMA IN SITU AND MICROINVASIVE CARCINOMA A lobule...
Images
DUCTAL CARCINOMA IN SITU INVOLVING <span class="search-highlight">LOBULES</span>  DCIS involving <span class="search-highlight">lobules</span> can be a...
Published: 01 January 2024
DUCTAL CARCINOMA IN SITU INVOLVING LOBULES Figure 8-29 DUCTAL CARCINOMA IN SITU INVOLVING LOBULES DCIS involving lobules can be a mimic of invasive or microinvasive carcinoma. Observing the lobulocentric arrangement of the tumor cell nests and the presence of a myoepithelial cell layer aid in the... More about this image found in DUCTAL CARCINOMA IN SITU INVOLVING LOBULES DCIS involving lobules can be a...
Images
BREAST <span class="search-highlight">LOBULES</span>  Looser intralobular stroma and denser collagenous inter lob...
Published: 01 January 2024
BREAST LOBULES Figure 1-2 BREAST LOBULES Looser intralobular stroma and denser collagenous inter lobular stroma are seen. More about this image found in BREAST LOBULES Looser intralobular stroma and denser collagenous inter lob...
Images
IMMUNOSTAIN FOR ESTROGEN RECEPTOR (ER)  In normal <span class="search-highlight">lobules</span>, the epithelial c...
Published: 01 January 2024
IMMUNOSTAIN FOR ESTROGEN RECEPTOR (ER) Figure 1-9 IMMUNOSTAIN FOR ESTROGEN RECEPTOR (ER) In normal lobules, the epithelial cells show variable nuclear expression with ER: some cells are negative, others demonstrate weak staining, and still others are strongly positive. More about this image found in IMMUNOSTAIN FOR ESTROGEN RECEPTOR (ER) In normal lobules, the epithelial c...
Images
LACTATING BREAST  A: In the lactating breast, the <span class="search-highlight">lobules</span> expand and have n...
Published: 01 January 2024
LACTATING BREAST Figure 1-13 LACTATING BREAST A: In the lactating breast, the lobules expand and have numerous acini. B: The epithelial cells are enlarged, have prominent cytoplasmic vacuolization; there may be hobnailing of the nuclei into lumens of the acini. The myoepithelial cells become att... More about this image found in LACTATING BREAST A: In the lactating breast, the lobules expand and have n...
Images
FIBROADENOMA  The well-circumscribed, <span class="search-highlight">lobulated</span> appearance of the tumor is ...
Published: 01 January 2024
FIBROADENOMA Figure 5-1 FIBROADENOMA The well-circumscribed, lobulated appearance of the tumor is illustrated grossly. The surface appears to bulge out from the background fibroadipose tissue. There are areas of grooving that correspond to the slit-like ducts characteristic of fibroadenoma. (Cour... More about this image found in FIBROADENOMA The well-circumscribed, lobulated appearance of the tumor is ...
Images
MYXOID FIBROADENOMA  Low- (A) and high- (B) power images of a <span class="search-highlight">lobulated</span> fib...
Published: 01 January 2024
MYXOID FIBROADENOMA Figure 5-16 MYXOID FIBROADENOMA Low- (A) and high- (B) power images of a lobulated fibroadenoma with myxoid stroma and an intracanalicular growth pattern. More about this image found in MYXOID FIBROADENOMA Low- (A) and high- (B) power images of a lobulated fib...
Images
ADENOMYOEPITHELIOMA  A: Low-power view shows a <span class="search-highlight">lobulated</span> epithelial-myoepit...
Published: 01 January 2024
ADENOMYOEPITHELIOMA Figure 7-40 ADENOMYOEPITHELIOMA A: Low-power view shows a lobulated epithelial-myoepithelial proliferation. B,C: At intermediate (B) and high (C) power, the two cell types are readily appreciated, with the epithelial component having more eosinophilic cytoplasm and the myoepi... More about this image found in ADENOMYOEPITHELIOMA A: Low-power view shows a lobulated epithelial-myoepit...
Images
RADIATION EFFECT  A: At lower power, an irradiated breast demonstrates atro...
Published: 01 January 2024
RADIATION EFFECT Figure 2-16 RADIATION EFFECT A: At lower power, an irradiated breast demonstrates atrophic lobules with thickened basement membrane. Hyperchromatic nuclei are apparent in the cells within the lobules even at this power. B: On high power, this lobule has scattered epithelial cell... More about this image found in RADIATION EFFECT A: At lower power, an irradiated breast demonstrates atro...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 18
Published: 01 January 2024
10.55418/9781933477367-01
ISBN-10: 1-933477-36-9
ISBN: 978-1-933477-36-7
... and the terminal duct lobular units (TDLUs) ( fig. 1-1 ). The most distal components of this branching ductal system are the acini, which are grouped together to form lobules. The lobules drain into ductules and ducts which, in turn, drain into large collecting ducts. Just below the surface of the nipple...
Images
Images
CLEAR CELL CHANGE  Low- (A) and high- (B) power images of two examples of c...
Published: 01 January 2024
CLEAR CELL CHANGE Figure 1-8 CLEAR CELL CHANGE Low- (A) and high- (B) power images of two examples of clear cell change in lobules. More about this image found in CLEAR CELL CHANGE Low- (A) and high- (B) power images of two examples of c...
Images
PREGNANCY-LIKE HYPERPLASIA  Cells with clear, vacuolated cytoplasm fill the...
Published: 01 January 2024
PREGNANCY-LIKE HYPERPLASIA Figure 1-7 PREGNANCY-LIKE HYPERPLASIA Cells with clear, vacuolated cytoplasm fill the lobules (A) and in other areas eosinophilic secretions are present in the acini (B). More about this image found in PREGNANCY-LIKE HYPERPLASIA Cells with clear, vacuolated cytoplasm fill the...
Images
INVASIVE LOBULAR CARCINOMA  The tumor cells infiltrate around normal ducts ...
Published: 01 January 2024
INVASIVE LOBULAR CARCINOMA Figure 8-34 INVASIVE LOBULAR CARCINOMA The tumor cells infiltrate around normal ducts and lobules in a “targetoid” pattern; this feature is typical of invasive lobular carcinoma. More about this image found in INVASIVE LOBULAR CARCINOMA The tumor cells infiltrate around normal ducts ...
Images
MICROARCHITECTURE OF NORMAL ADULT FEMALE BREAST TISSUE  A portion of an ext...
Published: 01 January 2024
MICROARCHITECTURE OF NORMAL ADULT FEMALE BREAST TISSUE Figure 1-1 MICROARCHITECTURE OF NORMAL ADULT FEMALE BREAST TISSUE A portion of an extralobular duct (arrow), terminal duct, and lobules, in turn composed of acini, is seen. More about this image found in MICROARCHITECTURE OF NORMAL ADULT FEMALE BREAST TISSUE A portion of an ext...
Images
PHYLLODES TUMOR  The cut surface of this benign phyllodes tumor demonstrate...
Published: 01 January 2024
PHYLLODES TUMOR Figure 5-21 PHYLLODES TUMOR The cut surface of this benign phyllodes tumor demonstrates a well-circumscribed, lobulated tumor. The tumor appears to bulge forth and there are grooves in the cut surface that correspond to the elongated ducts and slit-like spaces seen on microscopic ... More about this image found in PHYLLODES TUMOR The cut surface of this benign phyllodes tumor demonstrate...
Images
IMMUNOSTAINS FOR THE PRESENCE OF MYOEPITHELIAL CELLS  A: The myoepithelial ...
Published: 01 January 2024
IMMUNOSTAINS FOR THE PRESENCE OF MYOEPITHELIAL CELLS Figure 1-6 IMMUNOSTAINS FOR THE PRESENCE OF MYOEPITHELIAL CELLS A: The myoepithelial cell nuclei surrounding the ducts and lobules stain positively with p63; the epithelial cell nuclei are negative. B: Smooth muscle myosin heavy chain stains t... More about this image found in IMMUNOSTAINS FOR THE PRESENCE OF MYOEPITHELIAL CELLS A: The myoepithelial ...
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FLAT EPITHELIAL ATYPIA AND ATYPICAL LOBULAR HYPERPLASIA  In the center of t...
Published: 01 January 2024
FLAT EPITHELIAL ATYPIA AND ATYPICAL LOBULAR HYPERPLASIA Figure 3-5 FLAT EPITHELIAL ATYPIA AND ATYPICAL LOBULAR HYPERPLASIA In the center of the image is a single acinus lined by cells with low-grade cytologic atypia, i.e., FEA. Surrounding this space are lobules filled with, but not distended by,... More about this image found in FLAT EPITHELIAL ATYPIA AND ATYPICAL LOBULAR HYPERPLASIA In the center of t...
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DUCTAL CARCINOMA IN SITU: HIGH NUCLEAR GRADE WITH MICROINVASION  A: Interme...
Published: 01 January 2024
DUCTAL CARCINOMA IN SITU: HIGH NUCLEAR GRADE WITH MICROINVASION Figure 3-27 DUCTAL CARCINOMA IN SITU: HIGH NUCLEAR GRADE WITH MICROINVASION A: Intermediate-power view illustrates high nuclear grade DCIS with involvement of lobules (top of field). The inflammatory cell infiltrate is prominent. Sin... More about this image found in DUCTAL CARCINOMA IN SITU: HIGH NUCLEAR GRADE WITH MICROINVASION A: Interme...
Images
RESIDUAL CARCINOMA FOLLOWING NEOADJUVANT CHEMOTHERAPY  A: At lower power, t...
Published: 01 January 2024
RESIDUAL CARCINOMA FOLLOWING NEOADJUVANT CHEMOTHERAPY Figure 2-18 RESIDUAL CARCINOMA FOLLOWING NEOADJUVANT CHEMOTHERAPY A: At lower power, tumor cells are seen infiltrating around normal ducts and lobules. B: The cytologic atypia seen in tumor cells subsequent to administration of chemotherapeut... More about this image found in RESIDUAL CARCINOMA FOLLOWING NEOADJUVANT CHEMOTHERAPY A: At lower power, t...