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Images
Published: 01 December 2024
ADRENAL CORTICAL ADENOMA, ONCOCYTIC TYPE Figure 5-41 ADRENAL CORTICAL ADENOMA, ONCOCYTIC TYPE A nonfunctioning lesion, well circumscribed, with peritumoral adrenal cortex that is not atrophic (A), is composed of large eosinophilic cells in a lobular architecture with rare intratumoral More about this image found in ADRENAL CORTICAL ADENOMA, ONCOCYTIC TYPE A nonfunctioning lesion, well cir...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-05
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... pleomorphism and numerous nuclear pseudoinclusions. ADRENAL CORTICAL ADENOMA, ONCOCYTIC TYPE Figure 5-41 ADRENAL CORTICAL ADENOMA, ONCOCYTIC TYPE A nonfunctioning lesion, well circumscribed, with peritumoral adrenal cortex that is not atrophic (A), is composed of large eosinophilic cells in a lobular...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-12
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... extramedullary hematopoiesis ( 26 , 28 ). Variable findings are a lobular architecture and a prominent framework of nonendothelial supporting cells creating a “spleen-like” pattern of vascular channels ( 26 ) lined by hobnail endothelial cells (see fig. 12-8 ). Features of these benign lesions can be seen...
Images
Published: 01 September 2024
and is negative in benign endocervical epithelium. D,E: The differential diagnosis of endocervical glandular neoplasia includes lobular endocervical glandular hyperplasia (D) and tubal metaplasia (E). F,G: The differential diagnosis of endocervical glandular neoplasia includes microglandular hyperplasia (F More about this image found in ADENOCARCINOMA IN SITU (AIS) A: Biopsy fragment shows numerous endocervica...
Images
Published: 01 September 2024
and is negative in benign endocervical epithelium. D,E: The differential diagnosis of endocervical glandular neoplasia includes lobular endocervical glandular hyperplasia (D) and tubal metaplasia (E). F,G: The differential diagnosis of endocervical glandular neoplasia includes microglandular hyperplasia (F More about this image found in ADENOCARCINOMA IN SITU (AIS) A: Biopsy fragment shows numerous endocervica...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-05
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... portal inflammation Mild interface change Moderate interface change Severe interface change Lobular activity Absent Inflammation without hepatocyte dropout Focal hepatocyte necrosis Severe focal or confluent (but not bridging) necrosis Bridging necrosis Fibrosis Absent Exclusive portal...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-17
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... proliferation with a lobular arrangement. The endothelial cells lining these vessels are plump (hence the name bacillary epithelioid angiomatosis) and may even show cytologic atypia, thus mimicking neoplasia. The vascular stroma is either fibrotic or myxoid, and contains a neutrophil-rich inflammatory cell...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-06
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... inclusions Mixed dermal inflammatory infiltrate with increased vascularity Molluscum contagiosum Lobular epidermal hyperplasia with basal layer mitotic figures, cytoplasmic vacuolation, and eosinophilic globules in lower epidermis Compression of squamous epithelial nuclei by large intracytoplasmic...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-09
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... glandular neoplasia includes lobular endocervical glandular hyperplasia (D) and tubal metaplasia (E). F,G: The differential diagnosis of endocervical glandular neoplasia includes microglandular hyperplasia (F) and hyperplasia of mesonephric duct remnants (G). INVASIVE ENDOCERVICAL ADENOCARCINOMA Figure 9...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 18
Published: 01 January 2024
10.55418/9781933477367-04
ISBN-10: 1-933477-36-9
ISBN: 978-1-933477-36-7
...Table 4-1 CHARACTERISTIC IMMUNOHISTOCHEMICAL EXPRESSION PATTERNS FOR ANTIBODIES USED TO DIFFERENTIATE DUCTAL FROM LOBULAR CARCINOMA IN SITU E-Cadherin p120 Catenin Beta Catenin Ductal lesions Membranous pattern Membranous pattern Membranous pattern Lobular lesions Absence...
Images
Published: 01 January 2024
INVASIVE LOBULAR CARCINOMA Figure 8-35 INVASIVE LOBULAR CARCINOMA A: At low power, invasive lobular carcinoma with low nuclear grade can resemble chronic inflammation. B: Higher-power examination reveals the epithelial nature of the cells as well as the characteristic cytologic features. More about this image found in INVASIVE LOBULAR CARCINOMA A: At low power, invasive lobular carcinoma wit...
Images
Published: 01 January 2024
INVASIVE CARCINOMA WITH DUCTAL AND LOBULAR FEATURES Figure 8-19 INVASIVE CARCINOMA WITH DUCTAL AND LOBULAR FEATURES Some invasive carcinomas demonstrate a combination of well-formed glands and tumor cells that infiltrate in single files with some cytologic features of lobular differentiation More about this image found in INVASIVE CARCINOMA WITH DUCTAL AND LOBULAR FEATURES Some invasive carcinom...
Images
Published: 01 January 2024
LOBULAR CARCINOMA IN SITU INVOLVING SCLEROSING ADENOSIS Figure 6-7 LOBULAR CARCINOMA IN SITU INVOLVING SCLEROSING ADENOSIS A: This low-power image shows a concentric linear array of atypical epithelial cells, along with some nests at the left of the field. B: On high power, the lobular More about this image found in LOBULAR CARCINOMA IN SITU INVOLVING SCLEROSING ADENOSIS A: This low-power ...
Images
Published: 01 January 2024
LOBULAR CARCINOMA IN SITU WITH NECROSIS Figure 4-19 LOBULAR CARCINOMA IN SITU WITH NECROSIS A: This core needle biopsy was performed because of mammographically detected microcalcifications. The hematoxylin and eosin (H&E) image depicts acini greatly expanded by an atypical epithelial More about this image found in LOBULAR CARCINOMA IN SITU WITH NECROSIS A: This core needle biopsy was per...
Images
Published: 01 January 2024
INVASIVE LOBULAR CARCINOMA Figure 8-34 INVASIVE LOBULAR CARCINOMA The tumor cells infiltrate around normal ducts and lobules in a “targetoid” pattern; this feature is typical of invasive lobular carcinoma. More about this image found in INVASIVE LOBULAR CARCINOMA The tumor cells infiltrate around normal ducts ...
Images
Published: 01 January 2024
INVASIVE LOBULAR CARCINOMA, PLEOMORPHIC TYPE Figure 8-38 INVASIVE LOBULAR CARCINOMA, PLEOMORPHIC TYPE The nuclei are large, and vary considerably in size and shape, sufficient for a diagnosis of pleomorphic lobular carcinoma. More about this image found in INVASIVE LOBULAR CARCINOMA, PLEOMORPHIC TYPE The nuclei are large, and var...
Images
Published: 01 January 2024
ACINI OF A TERMINAL DUCT LOBULAR UNIT WITH PROMINENT MYOEPITHELIAL CELLS Figure 4-9 ACINI OF A TERMINAL DUCT LOBULAR UNIT WITH PROMINENT MYOEPITHELIAL CELLS These myoepithelial cells have abundant clear cytoplasm; given their location and prominence, they can be a mimic for the cells of lobular More about this image found in ACINI OF A TERMINAL DUCT LOBULAR UNIT WITH PROMINENT MYOEPITHELIAL CELLS T...
Images
Published: 01 January 2024
LOBULAR INVOLUTION IN POSTMENOPAUSAL BREAST Figure 1-14 LOBULAR INVOLUTION IN POSTMENOPAUSAL BREAST A few scattered atrophic acini are dispersed in either fibrotic (A) or fatty stroma (B). More about this image found in LOBULAR INVOLUTION IN POSTMENOPAUSAL BREAST A few scattered atrophic acini...
Images
Published: 01 January 2024
SECRETORY CHANGE Figure 2-24 SECRETORY CHANGE A: Low power shows a terminal duct lobular unit with secretory change, flocculent luminal secretions, and calcifications. B: High power demonstrates the abundant vacuolated cytoplasm and protuberant nuclei characteristic of this entity. More about this image found in SECRETORY CHANGE A: Low power shows a terminal duct lobular unit with secr...
Images
Published: 01 January 2024
FLAT EPITHELIAL ATYPIA AND ATYPICAL LOBULAR HYPERPLASIA Figure 3-5 FLAT EPITHELIAL ATYPIA AND ATYPICAL LOBULAR HYPERPLASIA In the center of the image is a single acinus lined by cells with low-grade cytologic atypia, i.e., FEA. Surrounding this space are lobules filled with, but not distended More about this image found in FLAT EPITHELIAL ATYPIA AND ATYPICAL LOBULAR HYPERPLASIA In the center of t...
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