LIVER STEATOSIS Figure 9-22 LIVER STEATOSIS A: Liver macroscopic specimen from a patient treated with didanosine (ddI) HAART, who died of metabolic lactic acidosis and had a soft yellow, diffusely steatotic liver. B: There is pronounced microvesicular steatosis devoid of inflammation. More about this image found in LIVER STEATOSIS A: Liver macroscopic specimen from a patient treated with ...

DISSEMINATED ADENOVIRUS INFECTION Figure 4-14 DISSEMINATED ADENOVIRUS INFECTION The liver is pale, with focally depressed necrotic areas. (Courtesy of Dr. L. S. de Haas, University of Pretoria, Pretoria, South Africa) More about this image found in DISSEMINATED ADENOVIRUS INFECTION The liver is pale, with focally depresse...

SEVERE YELLOW FEVER Figure 5-11 SEVERE YELLOW FEVER A,B: The liver shows extensive confluent zonal necrosis, which begins in the lobule midzone. (Courtesy of the CDC Infectious Disease Pathology Branch [IDPB]) More about this image found in SEVERE YELLOW FEVER A,B: The liver shows extensive confluent zonal necrosi...

VIRAL IMMUNOHISTOCHEMISTRY Figure 5-13 VIRAL IMMUNOHISTOCHEMISTRY A: Liver tissue shows hepatocyte and Kupffer cell positivity in yellow fever. B: Lung tissue in severe dengue with prominent macrophage staining. (Courtesy of the CDC IDPB) More about this image found in VIRAL IMMUNOHISTOCHEMISTRY A: Liver tissue shows hepatocyte and Kupffer ce...

LIVER IN EARLY HIV INFECTION Figure 9-21 LIVER IN EARLY HIV INFECTION A: Portal tract with a reactive lymphoid follicle. B: HIVp24 immunohistochemistry in liver portal tract lymphoid follicle shows virus in dendritic cells. More about this image found in LIVER IN EARLY HIV INFECTION A: Portal tract with a reactive lymphoid foll...

ACUTE TOXIC HEPATITIS Figure 9-23 ACUTE TOXIC HEPATITIS Liver biopsy shows acute hepatitis due to nevirapine. More about this image found in ACUTE TOXIC HEPATITIS Liver biopsy shows acute hepatitis due to nevirapine...

NONCIRRHOTIC PORTAL HYPERTENSION Figure 9-24 NONCIRRHOTIC PORTAL HYPERTENSION A: Trichrome stain of a liver biopsy with obliterated portal vein (bottom left, above bile duct). B: Portal vein sclerosis is highlighted on an elastic van Gieson stain. C: Low-power view of liver shows nodular regene... More about this image found in NONCIRRHOTIC PORTAL HYPERTENSION A: Trichrome stain of a liver biopsy with...

MARBURG VIRUS HISTOPATHOLOGY Figure 10-2 MARBURG VIRUS HISTOPATHOLOGY Patchy liver necrosis (A,B) and a hepatocyte with eosinophilic intracytoplasmic inclusions (C). (Courtesy of the CDC Infectious Disease Pathology Branch [IDPB]) More about this image found in MARBURG VIRUS HISTOPATHOLOGY Patchy liver necrosis (A,B) and a hepatocyte ...

EBOLA VIRUS HISTOPATHOLOGY Figure 10-3 EBOLA VIRUS HISTOPATHOLOGY A: The liver has necrotic foci. B,C: Intracytoplasmic filamentous eosinophilic inclusions are seen in hepatocytes. (Courtesy of the CDC IDPB) More about this image found in EBOLA VIRUS HISTOPATHOLOGY A: The liver has necrotic foci. B,C: Intracyto...

LIVER HISTOPATHOLOGY IN LASSA FEVER Figure 10-8 LIVER HISTOPATHOLOGY IN LASSA FEVER Portal tract inflammatory infiltrate and foci of necrosis (A), as well as apoptotic hepatocytes (B) are seen. (Courtesy of the CDC IDPB) More about this image found in LIVER HISTOPATHOLOGY IN LASSA FEVER Portal tract inflammatory infiltrate a...

Q FEVER Figure 12-36 Q FEVER A,B: In the liver, the typical fibrin ring granuloma morphology is seen at low (A) and high (B) power. C: Masson trichrome stain highlights the inflammatory cells and associated circular fibrinoid material deposition. (Courtesy of Dr. D. Jain, Yale University, New Ha... More about this image found in Q FEVER A,B: In the liver, the typical fibrin ring granuloma morphology is...

DISSEMINATED TUBERCULOSIS TO LIVER Figure 12-61 DISSEMINATED TUBERCULOSIS TO LIVER A small epithelioid cell granuloma (A) and numerous scattered acid-fast bacilli (B). More about this image found in DISSEMINATED TUBERCULOSIS TO LIVER A small epithelioid cell granuloma (A) ...

BRUCELLOSIS Figure 14-4 BRUCELLOSIS A: Brucellosis of the liver shows a small non-necrotizing granuloma. (Courtesy of Prof. S. Lucas, London, UK) B: Lymph node involvement shows extensive necrosis with surrounding histiocytes and scattered granulomas. C: Brucella spp organisms are highlighted by a modified Steiner silver stain. (Case courtesy of Dr. B. Pritt, Mayo Clinic, Rochester, MN) More about this image found in BRUCELLOSIS A: Brucellosis of the liver shows a small non-necrotizing gran...

BARTONELLA-ASSOCIATED PELIOSIS Figure 17-5 BARTONELLA-ASSOCIATED PELIOSIS In the liver (A) and bone marrow (B) characteristic randomly distributed and cystic, blood-filled cavities are seen, which typify this disorder. Warthin-Starry silver stain (C) demonstrates numerous etiologic bacteria. More about this image found in BARTONELLA-ASSOCIATED PELIOSIS In the liver (A) and bone ...

CONGENITAL SYPHILIS Figure 18-9 CONGENITAL SYPHILIS The wall of the intestinal tract (A) and liver (B) are involved. Note the scattered plasma cells. More about this image found in CONGENITAL SYPHILIS The wall of the intestinal tract (A) and liver (B) are...

MULTIPLE AMEBIC ABSCESSES Figure 26-2 MULTIPLE AMEBIC ABSCESSES Magnetic resonance imaging (MRI) of the liver. (Courtesy of Dr. A. Hoyos, Pontificia Bolivariana University, Medellín, Colombia) More about this image found in MULTIPLE AMEBIC ABSCESSES Magnetic resonance imaging (MRI) of the liver. (...

LARGE AMEBIC LIVER ABSCESS Figure 26-7 LARGE AMEBIC LIVER ABSCESS A: Circumscription and central white necrotic content. B: Isolated foci of associated hemorrhage which, if extensive, may impart a pink or brown hue to the necrotic debris. (Courtesy of the Department of Anatomical Pathology, Univ... More about this image found in LARGE AMEBIC LIVER ABSCESS A: Circumscription and central white necrotic c...

MALARIA Figure 27-2 MALARIA Extensive hemozoin pigment accumulation in the liver (A) and spleen (B), with striking dark brown to black tissue discoloration. (Courtesy of Prof. I. W. Simson, University of Pretoria, Pretoria, South Africa) More about this image found in MALARIA Extensive hemozoin pigment accumulation in the liver (A) and splee...