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Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 14
Published: 01 February 2023
DOI: 10.55418/9781933477268-3
ISBN-10: 1-933477-26-1
ISBN: 978-1-933477-26-8
...; and 4) other features such as cell polarity, keratinization, and frequency and position of mitotic figures. Like all HPV-associated squamous intraepithelial lesions (SILs), LSILs usually display nuclear abnormalities in the mid to superficial cell layers in the form of nuclear crowding and variably...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 14
Published: 01 February 2023
DOI: 10.55418/9781933477268-4
ISBN-10: 1-933477-26-1
ISBN: 978-1-933477-26-8
... Table 2 in reference 48 . b DSS = disease-specific survival. ATYPICAL GROWTH PATTERN Figure 4-13 ATYPICAL GROWTH PATTERN The presence of discrete keratin pearls and keratinizing nests with an “implant-like” or “seeding-like” appearance within the epithelium is an atypical pattern, often seen...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 14
Published: 01 February 2023
DOI: 10.55418/9781933477268-5
ISBN-10: 1-933477-26-1
ISBN: 978-1-933477-26-8
...Table 5-1 SQUAMOUS LESIONS OF THE VULVA Entity Features Differential Diagnosis (Exclusionary Features) Condyloma or seborrheic keratosis-like condyloma Discrete exophytic or verruciform Variable koilocytosis MIB1 positivity in superficial cell layers Usually low-risk HPV types...
Images
MUCINOUS CYSTIC NEOPLASM  Cytologically, thick colloid-<span class="search-highlight">like</span> mucin-containin...
Published: 01 March 2023
MUCINOUS CYSTIC NEOPLASM Figure 5-23 MUCINOUS CYSTIC NEOPLASM Cytologically, thick colloid-like mucin-containing degenerative inflammatory cells define the cyst as a mucin-producing cystic neoplasm and distinguish the mucin from contaminating gastrointestinal mucin (Diff Quik stain). More
Images
UNDIFFERENTIATED CARCINOMA WITH OSTEOCLAST-<span class="search-highlight">LIKE</span> GIANT CELLS  Left: Cross se...
Published: 01 March 2023
UNDIFFERENTIATED CARCINOMA WITH OSTEOCLAST-LIKE GIANT CELLS Figure 8-20 UNDIFFERENTIATED CARCINOMA WITH OSTEOCLAST-LIKE GIANT CELLS Left: Cross section reveals a soft, fleshy, somewhat hemorrhagic tumor. Right: A small tumor in the head of the pancreas lacks the fibrotic stroma of ductal adenoca... More
Images
UNDIFFERENTIATED CARCINOMA WITH OSTEOCLAST-<span class="search-highlight">LIKE</span> GIANT CELLS  Atypical monon...
Published: 01 March 2023
UNDIFFERENTIATED CARCINOMA WITH OSTEOCLAST-LIKE GIANT CELLS Figure 8-21 UNDIFFERENTIATED CARCINOMA WITH OSTEOCLAST-LIKE GIANT CELLS Atypical mononuclear cells are interspersed between large distinctive multinucleated giant cells without atypia (left). In contrast to the multinucleated giant cells... More
Images
UNDIFFERENTIATED CARCINOMA WITH OSTEOCLAST-<span class="search-highlight">LIKE</span> GIANT CELLS  The undifferen...
Published: 01 March 2023
UNDIFFERENTIATED CARCINOMA WITH OSTEOCLAST-LIKE GIANT CELLS Figure 8-22 UNDIFFERENTIATED CARCINOMA WITH OSTEOCLAST-LIKE GIANT CELLS The undifferentiated component (left) is associated an adenocarcinoma component (lower left and right). More
Images
UNDIFFERENTIATED CARCINOMA WITH OSTEOCLAST-<span class="search-highlight">LIKE</span> GIANT CELLS  Antibodies to ...
Published: 01 March 2023
UNDIFFERENTIATED CARCINOMA WITH OSTEOCLAST-LIKE GIANT CELLS Figure 8-23 UNDIFFERENTIATED CARCINOMA WITH OSTEOCLAST-LIKE GIANT CELLS Antibodies to p53 label the nuclei of the atypical mononuclear cells, but not the nuclei of the multinucleated osteoclast-like giant cells. More
Images
UNDIFFERENTIATED CARCINOMA WITH OSTEOCLAST-<span class="search-highlight">LIKE</span> GIANT CELLS  Mononuclear sp...
Published: 01 March 2023
UNDIFFERENTIATED CARCINOMA WITH OSTEOCLAST-LIKE GIANT CELLS Figure 8-24 UNDIFFERENTIATED CARCINOMA WITH OSTEOCLAST-LIKE GIANT CELLS Mononuclear spindled to epithelioid cells and osteoclast-like giant cells are seen (left: Papanicolaou stain; right: Thinprep). More
Images
UNDIFFERENTIATED CARCINOMA WITH OSTEOCLAST-<span class="search-highlight">LIKE</span> GIANT CELLS  Aggregates of ...
Published: 01 March 2023
UNDIFFERENTIATED CARCINOMA WITH OSTEOCLAST-LIKE GIANT CELLS Figure 8-25 UNDIFFERENTIATED CARCINOMA WITH OSTEOCLAST-LIKE GIANT CELLS Aggregates of mononuclear cells show a range in appearance from histiocytoid cells to bizarre sarcomatoid cells (left and right: Papanicolaou stain). More
Images
UNDIFFERENTIATED CARCINOMA WITH OSTEOCLAST-<span class="search-highlight">LIKE</span> GIANT CELLS  The osteoclast...
Published: 01 March 2023
UNDIFFERENTIATED CARCINOMA WITH OSTEOCLAST-LIKE GIANT CELLS Figure 8-26 UNDIFFERENTIATED CARCINOMA WITH OSTEOCLAST-LIKE GIANT CELLS The osteoclast-like giant cells often contain 10 or more bland-appearing, centrally clustered, and slightly overlapping nuclei with even chromatin and occasionally p... More
Images
ACINAR CELL CARCINOMA  Papilla formation (left) and a thyroid-<span class="search-highlight">like</span> follicul...
Published: 01 March 2023
ACINAR CELL CARCINOMA Figure 9-19 ACINAR CELL CARCINOMA Papilla formation (left) and a thyroid-like follicular pattern (right) are rare morphologic variations. More
Images
PANCREATIC NEUROENDOCRINE TUMOR  “Paraganglioma-<span class="search-highlight">like</span>” pattern with tight sm...
Published: 01 March 2023
PANCREATIC NEUROENDOCRINE TUMOR Figure 12-22 PANCREATIC NEUROENDOCRINE TUMOR “Paraganglioma-like” pattern with tight small nests. More
Images
GANGLIOCYTIC PARAGANGLIOMA  Epithelioid, ganglion-<span class="search-highlight">like</span>, and Schwann cells a...
Published: 01 March 2023
GANGLIOCYTIC PARAGANGLIOMA Figure 12-79 GANGLIOCYTIC PARAGANGLIOMA Epithelioid, ganglion-like, and Schwann cells are present. More
Images
PARADUODENAL CHRONIC PANCREATITIS  Cord-<span class="search-highlight">like</span> fibrosis between the duodenum ...
Published: 01 March 2023
PARADUODENAL CHRONIC PANCREATITIS Figure 15-19 PARADUODENAL CHRONIC PANCREATITIS Cord-like fibrosis between the duodenum and the pancreatic parenchyma involves the muscular wall of the duodenum and focally the pancreatic tissue. More
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 15
Published: 01 March 2023
DOI: 10.55418/9781933477275-08
ISBN-10: 1-933477-27-X
ISBN: 978-1-933477-27-5
... carcinoma, colloid carcinoma, hepatoid carcinoma, medullary carcinoma, signet ring cell carcinoma, undifferentiated carcinoma, and undifferentiated carcinoma with osteoclast-like giant cells. ADENOSQUAMOUS CARCINOMA Definition.  Adenosquamous carcinoma is a malignant epithelial neoplasm...
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DUCTAL ADENOCARCINOMA  Foamy gland pattern (left, right), with microvesicul...
Published: 01 March 2023
DUCTAL ADENOCARCINOMA Figure 7-23 DUCTAL ADENOCARCINOMA Foamy gland pattern (left, right), with microvesicular cytoplasm and a brush border-like zone. More
Images
SOLID PSEUDOPAPILLARY NEOPLASM  Balls of myxoid matrix result in a cylindro...
Published: 01 March 2023
SOLID PSEUDOPAPILLARY NEOPLASM Figure 11-14 SOLID PSEUDOPAPILLARY NEOPLASM Balls of myxoid matrix result in a cylindroma-like (left) or microcystic (right) appearance. More
Images
DESMOPLASTIC SMALL ROUND CELL TUMOR  Immunolabeling for desmin, with a dist...
Published: 01 March 2023
DESMOPLASTIC SMALL ROUND CELL TUMOR Figure 13-27 DESMOPLASTIC SMALL ROUND CELL TUMOR Immunolabeling for desmin, with a distinctive peri-nuclear dot-like pattern. More
Images
SOLITARY FIBROUS TUMOR  Variably cellular cords of spindle cells surround l...
Published: 01 March 2023
SOLITARY FIBROUS TUMOR Figure 13-21 SOLITARY FIBROUS TUMOR Variably cellular cords of spindle cells surround lobules of pancreatic parenchyma. Slit-like vessels are present. More