MUCINOUS CYSTIC NEOPLASM Figure 5-23 MUCINOUS CYSTIC NEOPLASM Cytologically, thick colloid-like mucin-containing degenerative inflammatory cells define the cyst as a mucin-producing cystic neoplasm and distinguish the mucin from contaminating gastrointestinal mucin (Diff Quik stain). More

UNDIFFERENTIATED CARCINOMA WITH OSTEOCLAST-LIKE GIANT CELLS Figure 8-20 UNDIFFERENTIATED CARCINOMA WITH OSTEOCLAST-LIKE GIANT CELLS Left: Cross section reveals a soft, fleshy, somewhat hemorrhagic tumor. Right: A small tumor in the head of the pancreas lacks the fibrotic stroma of ductal adenoca... More

UNDIFFERENTIATED CARCINOMA WITH OSTEOCLAST-LIKE GIANT CELLS Figure 8-21 UNDIFFERENTIATED CARCINOMA WITH OSTEOCLAST-LIKE GIANT CELLS Atypical mononuclear cells are interspersed between large distinctive multinucleated giant cells without atypia (left). In contrast to the multinucleated giant cells... More

UNDIFFERENTIATED CARCINOMA WITH OSTEOCLAST-LIKE GIANT CELLS Figure 8-22 UNDIFFERENTIATED CARCINOMA WITH OSTEOCLAST-LIKE GIANT CELLS The undifferentiated component (left) is associated an adenocarcinoma component (lower left and right). More

UNDIFFERENTIATED CARCINOMA WITH OSTEOCLAST-LIKE GIANT CELLS Figure 8-23 UNDIFFERENTIATED CARCINOMA WITH OSTEOCLAST-LIKE GIANT CELLS Antibodies to p53 label the nuclei of the atypical mononuclear cells, but not the nuclei of the multinucleated osteoclast-like giant cells. More

UNDIFFERENTIATED CARCINOMA WITH OSTEOCLAST-LIKE GIANT CELLS Figure 8-24 UNDIFFERENTIATED CARCINOMA WITH OSTEOCLAST-LIKE GIANT CELLS Mononuclear spindled to epithelioid cells and osteoclast-like giant cells are seen (left: Papanicolaou stain; right: Thinprep). More

UNDIFFERENTIATED CARCINOMA WITH OSTEOCLAST-LIKE GIANT CELLS Figure 8-25 UNDIFFERENTIATED CARCINOMA WITH OSTEOCLAST-LIKE GIANT CELLS Aggregates of mononuclear cells show a range in appearance from histiocytoid cells to bizarre sarcomatoid cells (left and right: Papanicolaou stain). More

UNDIFFERENTIATED CARCINOMA WITH OSTEOCLAST-LIKE GIANT CELLS Figure 8-26 UNDIFFERENTIATED CARCINOMA WITH OSTEOCLAST-LIKE GIANT CELLS The osteoclast-like giant cells often contain 10 or more bland-appearing, centrally clustered, and slightly overlapping nuclei with even chromatin and occasionally p... More

ACINAR CELL CARCINOMA Figure 9-19 ACINAR CELL CARCINOMA Papilla formation (left) and a thyroid-like follicular pattern (right) are rare morphologic variations. More

PANCREATIC NEUROENDOCRINE TUMOR Figure 12-22 PANCREATIC NEUROENDOCRINE TUMOR “Paraganglioma-like” pattern with tight small nests. More

GANGLIOCYTIC PARAGANGLIOMA Figure 12-79 GANGLIOCYTIC PARAGANGLIOMA Epithelioid, ganglion-like, and Schwann cells are present. More

PARADUODENAL CHRONIC PANCREATITIS Figure 15-19 PARADUODENAL CHRONIC PANCREATITIS Cord-like fibrosis between the duodenum and the pancreatic parenchyma involves the muscular wall of the duodenum and focally the pancreatic tissue. More

DUCTAL ADENOCARCINOMA Figure 7-23 DUCTAL ADENOCARCINOMA Foamy gland pattern (left, right), with microvesicular cytoplasm and a brush border-like zone. More

SOLID PSEUDOPAPILLARY NEOPLASM Figure 11-14 SOLID PSEUDOPAPILLARY NEOPLASM Balls of myxoid matrix result in a cylindroma-like (left) or microcystic (right) appearance. More

DESMOPLASTIC SMALL ROUND CELL TUMOR Figure 13-27 DESMOPLASTIC SMALL ROUND CELL TUMOR Immunolabeling for desmin, with a distinctive peri-nuclear dot-like pattern. More

SOLITARY FIBROUS TUMOR Figure 13-21 SOLITARY FIBROUS TUMOR Variably cellular cords of spindle cells surround lobules of pancreatic parenchyma. Slit-like vessels are present. More