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Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-08
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... with hematologic disease, particularly sickle cell anemia. It may also occur in those with human immunodeficiency virus (HIV) infection, malaria, iron deficiency anemia, myelofibrosis, leukemia, and many congenital diseases of erythrocytes, such as spherocytosis and thalassemia. TAC has an acute presentation...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-03
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... occurred in children who have lymphoblastic leukemia, other malignancies, HIV infection, autoimmune disease, or stem cell transplantation ( 58 ). MIBE mortality is high and no effective treatment is available. Interestingly, recent reports of SSPE in HIV-infected individuals have blurred the typical...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-04
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... . 83. Tamaki K , Kinjo T , Aoyama H , et al . Fatal pneumonia and viremia due to human parainfluenza virus type 1 in a patient with adult T-cell leukemia-lymphoma treated with mogamulizumab . J Infect Chemother 2015 ; 21 : 820 - 3 . 84. Tanir-Basaranoglu S , Aykac...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-09
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... of these tumors. Predisposing factors include advanced age, immunosuppression, and chronic lymphocytic leukemia. Merkel cell carcinomas are painless, violaceous nodules or plaques that grow rapidly. These neoplasms have a bad prognosis and one third present with local lymph node or systemic metastasis. Pathologic...
Images
Published: 01 January 2024
CHRONIC LYMPHOCYTIC LEUKEMIA/SMALL LYMPHOCYTIC LYMPHOMA (CLL/SLL) Figure 12-2 CHRONIC LYMPHOCYTIC LEUKEMIA/SMALL LYMPHOCYTIC LYMPHOMA (CLL/SLL) A: At low power, numerous lymphocytes are seen infiltrating the breast stroma. B: A higher-power image demonstrates the monotonous appearance of the lym... More about this image found in CHRONIC LYMPHOCYTIC LEUKEMIA/SMALL LYMPHOCYTIC LYMPHOMA (CLL/SLL) A: At lo...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 18
Published: 01 January 2024
10.55418/9781933477367-12
ISBN-10: 1-933477-36-9
ISBN: 978-1-933477-36-7
... lymphocytic leukemia (CLL)/small lymphocytic lymphoma (SLL), a condition more frequently affecting older adults. In addition to knowledge of the patient history, clues to the diagnosis of SLL are the presence of aggregates of monotonous lymphocytes that infiltrate the stroma and a relative absence of other...
Images
Published: 15 November 2023
NONBACTERIAL THROMBOTIC ENDOCARDITIS: AORTIC VALVE Figure 11-2 NONBACTERIAL THROMBOTIC ENDOCARDITIS: AORTIC VALVE Numerous vegetations are present on the ventricular aspect of this aortic valve in a patient with leukemia. More about this image found in NONBACTERIAL THROMBOTIC ENDOCARDITIS: AORTIC VALVE Numerous vegetations ar...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 18
Published: 01 January 2024
10.55418/9781933477367-14
ISBN-10: 1-933477-36-9
ISBN: 978-1-933477-36-7
.... Lymphoproliferative Disorders While beyond the scope of this discussion, most patients undergoing axillary lymph node surgery for a diagnosis of breast cancer are older, and often within the age range of patients with comorbidities such as chronic lymphocytic leukemia/small cell lymphoma. It can be all too easy...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 18
Published: 01 January 2024
10.55418/9781933477367-08
ISBN-10: 1-933477-36-9
ISBN: 978-1-933477-36-7
... Leukemias and lymphomas Ovary GI Li-Fraumeni syndrome, TP53-associated TP53 Regulation of cell division (tumor suppression) Usually IBC, NST Grade 3 more frequent HER2 positivity more frequent Adrenocortical Brain Leukemia Sarcoma/GI Melanoma/Lung Li-Fraumeni syndrome, CHEK2-associated...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch52
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... , Nouno R , Kouno K . Massive cardiac involvement of adult T-cell leukemia/lymphoma. An autopsy case . Arch Pathol Lab Med 1991 ; 115 : 1052 - 4 . 102. Messner G , Harting MT , Russo P , et al . Surgical management of metastatic melanoma to the ventricle . Tex Heart...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch11
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
.... NONBACTERIAL THROMBOTIC ENDOCARDITIS: AORTIC VALVE Figure 11-2 NONBACTERIAL THROMBOTIC ENDOCARDITIS: AORTIC VALVE Numerous vegetations are present on the ventricular aspect of this aortic valve in a patient with leukemia. NONBACTERIAL THROMBOTIC ENDOCARDITIS Figure 11-3 NONBACTERIAL THROMBOTIC...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch16
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... of PDGFRA, PDGFRB, FGFR1, PCM1-JAK2 Chronic eosinophilic leukemia, not otherwise specified Lymphocytic variant of hypereosinophilic syndrome (L-HES) Polyclonal hypereosinophilia caused by Th2 cytokine production from immunophenotypically aberrant and/or clonal T cells Idiopathic...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 16
Published: 01 August 2023
10.55418/9781933477282-16
ISBN-10: 1-933477-28-8
ISBN: 978-1-933477-28-2
... 2001 ; 8 : 200 - 17 . 212. Osborne BM , Robboy SJ . Lymphomas or leukemia presenting as ovarian tumors. An analysis of 42 cases . Cancer 1983 ; 52 : 1933 - 43 . 213. Vang R , Medeiros LJ , Warnke RA , Higgins JP , Deavers MT . Ovarian non...
Book Chapter
Book: Tumors of the Pancreas
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 15
Published: 01 March 2023
10.55418/9781933477275-14
ISBN-10: 1-933477-27-X
ISBN: 978-1-933477-27-5
... 2 10 6 4 1 21 Total 815 208 (25%) 103 (13%) 91 (11%) 78 (10%) 49 (6%) 33 (4%) 30 (4%) 223 (27%) c a Modified from reference 10 . b N = Total number. c Includes lymphoma/leukemia and metastatic neoplasms infrequently seen in any individual series...
Book Chapter
Book: Tumors of the Pancreas
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 15
Published: 01 March 2023
10.55418/9781933477275-13
ISBN-10: 1-933477-27-X
ISBN: 978-1-933477-27-5
... , Amielh D , Chevallier C , Mariette C . Isolated granulocytic sarcoma of the pancreas: a tricky diagnostic for primary pancreatic extramedullary acute myeloid leukemia . World J Surg Oncol 2012 ; 10 : 13 . 157. Ishii A , Kondo T , Oka T , Nakamoto Y , Takaori...
Book Chapter
Book: Tumors of the Pancreas
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 15
Published: 01 March 2023
10.55418/9781933477275-11
ISBN-10: 1-933477-27-X
ISBN: 978-1-933477-27-5
... . Surg Today 2011 ; 41 : 865 - 71 . 36. Acebo E , Rodilla IG , Torío B , et al Papillary cystic tumor of the pancreas coexisting with hairy cell leukemia . Pathology 2000 ; 32 : 216 - 9 . 37. Watanabe D , Miura K , Goto T , Nanjo H , Yamamoto Y...
Book Chapter
Book: Tumors of the Pancreas
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 15
Published: 01 March 2023
10.55418/9781933477275-01
ISBN-10: 1-933477-27-X
ISBN: 978-1-933477-27-5
... of the bone marrow may be affected, leading to anemia and clotting abnormalities. Thirty percent of children with this syndrome develop leukemia or aplastic anemia by adulthood ( 183 ). Dysfunctional hedgehog signaling may play a role in this anomaly since hedgehog-mutant mice develop malformations similar...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 14
Published: 01 February 2023
10.55418/9781933477268-5
ISBN-10: 1-933477-26-1
ISBN: 978-1-933477-26-8
... female genital tract ( 482 – 484 ), although in many cases, it is the primary presentation of the myeloid malignancy. Rare cases represent recurrence/relapse of a previously treated acute myeloid leukemia. Clinical Features. Patient presentation depends on the precise location of involvement...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 13
Published: 01 November 2022
10.55418/9781933477251-3
ISBN-10: 1-933477-25-3
ISBN: 978-1-933477-25-1
..., and chronic myeloid leukemia; however, they can cause hypothyroidism ( 110 , 111 ). Hypothyroidism occurs in patients with previously normal thyroid function and may be preceded by a destructive thyroiditis and transient suppression of TSH ( 112 ). In patients with preexisting hypothyroidism, thyroid hormone...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 13
Published: 01 November 2022
10.55418/9781933477251-2
ISBN-10: 1-933477-25-3
ISBN: 978-1-933477-25-1
... of the MLL methyltransferase complex, a role thought to promote tumorigenesis, but may also enhance the activity of MYC, independent of H3K4me3 ( 130 ). Menin is an oncogenic factor in MLL fusion leukemia. It interacts with SMAD proteins which, along with the transcription factor Pit-1, are involved...
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