ADRENAL CORTICAL ADENOMA WITH MYELOLIPOMA Figure 5-16 ADRENAL CORTICAL ADENOMA WITH MYELOLIPOMA A 7.5-cm lesion with a peripheral cortical cell component is associated with a prominent myelolipomatous component with hemorrhage and infarct-type necrosis. More about this image found in ADRENAL CORTICAL ADENOMA WITH MYELOLIPOMA A 7.5-cm lesion with a periphera...

INCIDENTALLY DISCOVERED, NONFUNCTIONAL ADRENAL CORTICAL ADENOMA Figure 5-21 INCIDENTALLY DISCOVERED, NONFUNCTIONAL ADRENAL CORTICAL ADENOMA The lesion measured 5 cm and presented heterogeneous morphologic features, including alveolar with lipid-rich clear cells (A), alveolar/pseudoglandular with ... More about this image found in INCIDENTALLY DISCOVERED, NONFUNCTIONAL ADRENAL CORTICAL ADENOMA The lesion...

ALDOSTERONE-SECRETING ADRENAL CORTICAL ADENOMA Figure 5-36 ALDOSTERONE-SECRETING ADRENAL CORTICAL ADENOMA The lesion is composed of a predominant clear cell population; the peritumoral adrenal cortex is not atrophic. More about this image found in ALDOSTERONE-SECRETING ADRENAL CORTICAL ADENOMA The lesion is composed of a...

ALDOSTERONE-SECRETING ADRENAL CORTICAL ADENOMA Figure 5-37 ALDOSTERONE-SECRETING ADRENAL CORTICAL ADENOMA The lesion is composed of a population of both compact and clear cells; the peritumoral adrenal cortex is not atrophic. More about this image found in ALDOSTERONE-SECRETING ADRENAL CORTICAL ADENOMA The lesion is composed of a...

ADRENAL CORTICAL ADENOMA, ONCOCYTIC TYPE Figure 5-41 ADRENAL CORTICAL ADENOMA, ONCOCYTIC TYPE A nonfunctioning lesion, well circumscribed, with peritumoral adrenal cortex that is not atrophic (A), is composed of large eosinophilic cells in a lobular architecture with rare intratumoral lymphocytes... More about this image found in ADRENAL CORTICAL ADENOMA, ONCOCYTIC TYPE A nonfunctioning lesion, well cir...

ADRENAL CORTICAL CARCINOMA Figure 6-4 ADRENAL CORTICAL CARCINOMA This 19-cm adrenal lesion in the left adrenal gland has marked intratumoral heterogeneity. Upper panels: CT scan. Basal (A, >20 HU); heterogeneous uptake in the venous (B) and arterial (C) phases. Lower panels: MRI scan. T2 phase... More about this image found in ADRENAL CORTICAL CARCINOMA This 19-cm adrenal lesion in the left adrenal g...

ONCOCYTIC ADRENAL CORTICAL CARCINOMA Figure 6-5 ONCOCYTIC ADRENAL CORTICAL CARCINOMA CT scan of 10-cm adrenal lesion. Basal (20 HU), clearly defined borders (A); poor and heterogeneous uptake in the venous (B) and arterial (C) phases. (Courtesy of Prof. A. Veltri and Dr. F. Solitro, San Luigi Hos... More about this image found in ONCOCYTIC ADRENAL CORTICAL CARCINOMA CT scan of 10-cm adrenal lesion. Basa...

PHEOCHROMOCYTOMA: EXTENSIVE CYSTIC DEGENERATION Figure 8-11 PHEOCHROMOCYTOMA: EXTENSIVE CYSTIC DEGENERATION This lesion was identified as a large cyst on imaging; focal calcification is present in the wall. More about this image found in PHEOCHROMOCYTOMA: EXTENSIVE CYSTIC DEGENERATION This lesion was identified...

PULMONARY PARAGANGLIOMA Figure 9-32 PULMONARY PARAGANGLIOMA A: This paraganglioma was a solitary lesion initially interpreted as an epithelial pulmonary NET. The patient was found to have a hereditary SDHC mutation. No other primary tumors were found and this tumor contained abundant sustentacular cells. In view of the clinical and histologic findings and the low metastasis frequency associated with SDHC mutation, the tumor was consistent with a primary pulmonary paraganglioma. B: High magnification shows nested architecture and cells of varied sizes. C: S-100 protein highlights sustentacular cells. More about this image found in PULMONARY PARAGANGLIOMA A: This paraganglioma was a solitary lesion initia...

GANGLIONEUROMA Figure 11-32 GANGLIONEUROMA This groin lesion in a 15-year-old boy consisted entirely of mature elements, both the stroma, which is paucicellular schwannian stroma, and the cellular compartment, which was composed of scattered mature ganglion cells, with the typical ample amount of... More about this image found in GANGLIONEUROMA This groin lesion in a 15-year-old boy consisted entirely o...

PRIMARY BILATERAL MACRONODULAR ADRENOCORTICAL DISEASE ASSOCIATED WITH CORTISOL OVERSECRETION Figure 4-16 PRIMARY BILATERAL MACRONODULAR ADRENOCORTICAL DISEASE ASSOCIATED WITH CORTISOL OVERSECRETION Heterogeneous architectural patterns with diffuse and pseudonodular lesions from the adrenal lesion... More about this image found in PRIMARY BILATERAL MACRONODULAR ADRENOCORTICAL DISEASE ASSOCIATED WITH CORTI...

COMPLEX OF MYXOMA AND SPOTTY PIGMENTATION Figure 4-22 COMPLEX OF MYXOMA AND SPOTTY PIGMENTATION A: A young girl with multiple pigmented lesions about the mouth. The patient also had a darkly pigmented lesion on the vulva, probably a blue nevus. B: Cutaneous myxoma on the breast of the same patie... More about this image found in COMPLEX OF MYXOMA AND SPOTTY PIGMENTATION A: A young girl with multiple pi...

ADRENAL CORTICAL ADENOMA IN CUSHING SYNDROME Figure 5-20 ADRENAL CORTICAL ADENOMA IN CUSHING SYNDROME A reticulin stain highlights the regular architecture of the lesion. More about this image found in ADRENAL CORTICAL ADENOMA IN CUSHING SYNDROME A reticulin stain highlights ...

MELAN-A IN ADRENAL CORTICAL CARCINOMA Figure 6-32 MELAN-A IN ADRENAL CORTICAL CARCINOMA Melan-A expression in ACC is usually heterogeneous, either diffuse (A) or focal (B) even within the same lesion. More about this image found in MELAN-A IN ADRENAL CORTICAL CARCINOMA Melan-A expression in ACC is usually...

PHEOCHROMOCYTOMA Figure 8-5 PHEOCHROMOCYTOMA A: The cut surface of pheochromocytoma may be firm and gray-tan, resembling medulla. B: The mass may distort the entire gland, which is attenuated around the lesion. More about this image found in PHEOCHROMOCYTOMA A: The cut surface of pheochromocytoma may be firm and gr...

POORLY DIFFERENTIATED NEUROBLASTOMA Figure 11-28 POORLY DIFFERENTIATED NEUROBLASTOMA Very cellular tumor, composed of small blue round cells. The scattered small amount of neuropil indicates the neuroblastic nature of the lesion. More about this image found in POORLY DIFFERENTIATED NEUROBLASTOMA Very cellular tumor, composed of small...

ADRENAL CORTICAL CARCINOMA: ARCHITECTURAL PATTERNS Figure 6-11 ADRENAL CORTICAL CARCINOMA: ARCHITECTURAL PATTERNS Tumor architecture may be extremely variable, with patterns including the solid (A), “insular” (B), or large trabecular (C), frequently present within the same lesion. More about this image found in ADRENAL CORTICAL CARCINOMA: ARCHITECTURAL PATTERNS Tumor architecture may ...