MENINGOCOCCEMIA Figure 11-7 MENINGOCOCCEMIA Meningococcal skin lesion (A) with relatively inapparent bacterial organisms. Gram stain on heart tissue (B), in contrast, shows numerous, more obvious intracellular gram-negative cocci. (Courtesy of the CDC IDPB) More about this image found in MENINGOCOCCEMIA Meningococcal skin lesion (A) with relatively inapparent b...

NOCARDIOSIS Figure 12-23 NOCARDIOSIS A central nervous system (CNS) inflammatory lesion with abscess formation (A,B), scattered beaded gram-positive Nocardia bacilli (C), and numerous single and partly clustered filamentous bacteria with a Grocott methenamine silver (GMS) stain (D). (C: courtesy of the CDC PHIL) More about this image found in NOCARDIOSIS A central nervous system (CNS) inflammatory lesion with absces...

AFRICAN TICK BITE FEVER Figure 14-33 AFRICAN TICK BITE FEVER The skin lesion shows the typical eschar (A), prominent purpuric dermal erythrocyte extravasation (B), and vasculitic change with striking fibrinoid necrosis and surrounding predominantly mononuclear inflammatory cell infiltration (C). ... More about this image found in AFRICAN TICK BITE FEVER The skin lesion shows the typical eschar (A), prom...

TYPICAL FACIAL SKIN LESION IN PINTA Figure 15-34 TYPICAL FACIAL SKIN LESION IN PINTA There is “slate blue” discoloration. (Courtesy of the CDC PHIL) More about this image found in TYPICAL FACIAL SKIN LESION IN PINTA There is “slate blue” discoloration. (...

BARTONELLOSES Figure 17-2 BARTONELLOSES A,B: Skin lesion of cat scratch disease (A) contrasted with bacillary angiomatosis (B). (A: courtesy of the Centers for Disease Control and Prevention [CDC] Public Health Image Library [PHIL]; B: courtesy of the CDC Infectious Disease Pathology Branch [IDPB... More about this image found in BARTONELLOSES A,B: Skin lesion of cat scratch disease (A) contrasted with ...

BACILLARY ANGIOMATOSIS Figure 17-4 BACILLARY ANGIOMATOSIS A: The dermal vasoproliferative lesion with associated mixed inflammation shows overlying epidermal hyperplasia. B: Endothelial cells appear plump, with prominent associated neutrophils. C: Warthin-Starry silver stain highlights numerous clusters of etiologic Bartonella organisms. (Courtesy of the CDC IDPB) More about this image found in BACILLARY ANGIOMATOSIS A: The dermal vasoproliferative lesion with associa...

CUTANEOUS LESION OF SECONDARY SYPHILIS Figure 18-4 CUTANEOUS LESION OF SECONDARY SYPHILIS Prominent psoriasiform epidermal hyperplasia and spongiosis are seen. (Courtesy of Dr. A. L. Canales, Harvard Medical School, Boston, MA) More about this image found in CUTANEOUS LESION OF SECONDARY SYPHILIS Prominent psoriasiform epidermal hy...

LOBOMYCOSIS OF THE NASAL BRIDGE Figure 24-20 LOBOMYCOSIS OF THE NASAL BRIDGE A nodular keloid-like lesion (A) shows an irregular smooth shiny surface (B). (Image courtesy of Dr. M. Sangueza, Hospital Obrero, La Paz, Bolivia) More about this image found in LOBOMYCOSIS OF THE NASAL BRIDGE A nodular keloid-like lesion (A) shows an ...

HUMAN HERPESVIRUSES 1 TO 3 SKIN LESIONS Figure 6-5 HUMAN HERPESVIRUSES 1 TO 3 SKIN LESIONS The histopathology of the three is similar and shows vesicle formation (A) and characteristic syncytial cells with nuclear inclusions (B,D). Herpes virus is confirmed using specific immunohistochemical stai... More about this image found in HUMAN HERPESVIRUSES 1 TO 3 SKIN LESIONS The histopathology of the three is...

MPOX Figure 6-11 MPOX Microscopic features of skin lesions. (Courtesy of the CDC IDPB) A: Early changes showing a lichenoid papillary dermal and perivascular mixed inflammatory cell infiltrate, which includes lymphocytes, macrophages, and rare eosinophils. Single dyskeratotic cells are visible i... More about this image found in MPOX Microscopic features of skin lesions. (Courtesy of the CDC IDPB) A: ...

MPOX Figure 6-11 MPOX Microscopic features of skin lesions. (Courtesy of the CDC IDPB) A: Early changes showing a lichenoid papillary dermal and perivascular mixed inflammatory cell infiltrate, which includes lymphocytes, macrophages, and rare eosinophils. Single dyskeratotic cells are visible i... More about this image found in MPOX Microscopic features of skin lesions. (Courtesy of the CDC IDPB) A: ...

TUBERCULOID LEPROSY Figure 15-14 TUBERCULOID LEPROSY Typical hypopigmented trunk skin lesions. (Courtesy of the CDC PHIL) More about this image found in TUBERCULOID LEPROSY Typical hypopigmented trunk skin lesions. (Courtesy of...

LEPROMATOUS LEPROSY Figure 15-15 LEPROMATOUS LEPROSY Typical infiltrative lesions on the face and hand. Note the early leonine or lion-like facial features, with prominent skin induration and furrowed creases (A); diffusely infiltrated and grossly thickened digits (B). (Courtesy of the CDC PHIL) More about this image found in LEPROMATOUS LEPROSY Typical infiltrative lesions on the face and hand. Not...

LYMPHOCUTANEOUS SPOROTRICHOSIS Figure 24-2 LYMPHOCUTANEOUS SPOROTRICHOSIS Typical nodular lesions are along the line of lymphatic drainage on the forearm. (Courtesy of the Division of Dermatology, University of the Witwatersrand, Johannesburg, South Africa) More about this image found in LYMPHOCUTANEOUS SPOROTRICHOSIS Typical nodular lesions are along the line ...

TINEA CRURIS Figure 24-32 TINEA CRURIS Central clearing with an active erythematous lesional edge. (Courtesy of Prof. A. Mosam, University of KwaZulu-Natal, Durben, South Africa) More about this image found in TINEA CRURIS Central clearing with an active erythematous lesional edge. (...

SKIN LESIONS DUE TO FLA INFECTION Figure 25-12 SKIN LESIONS DUE TO FLA INFECTION Ulcerative, nodular, and focally violaceous features are seen. More about this image found in SKIN LESIONS DUE TO FLA INFECTION Ulcerative, nodular, and focally violace...

JC VIRUS Figure 3-37 JC VIRUS This virus reaches the CNS via a hematogenous route and early lesions are maximal at the gray-white matter junction. In later stages of disease, as seen here at autopsy, the demyelinating lesions coalesce and form large, partially cavitated lesions (at right and top)... More about this image found in JC VIRUS This virus reaches the CNS via a hematogenous route and early les...

PARACOCCIDIOIDOMYCOSIS Figure 21-15 PARACOCCIDIOIDOMYCOSIS Juvenile form involving the skin (A), and chronic adult form showing lesions of the eye and tongue, as well as a destructive lesion that spans the mouth and nose (B). Note the granular “mulberry”-like appearance of the mucosa. (Courtesy o... More about this image found in PARACOCCIDIOIDOMYCOSIS Juvenile form involving the skin (A), and chronic a...

COLPOSCOPIC FEATURES OF LOW-GRADE AND HIGH-GRADE SQUAMOUS INTRAEPITHELIAL LESIONS (LSIL, HSIL) AND CARCINOMA Figure 9-35 COLPOSCOPIC FEATURES OF LOW-GRADE AND HIGH-GRADE SQUAMOUS INTRAEPITHELIAL LESIONS (LSIL, HSIL) AND CARCINOMA A: LSIL. B: HSIL. C: Squamous cell carcinoma. (Courtesy of Dr. L.... More about this image found in COLPOSCOPIC FEATURES OF LOW-GRADE AND HIGH-GRADE SQUAMOUS INTRAEPITHELIAL L...