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Images
Figure 15-13
Published: 01 September 2024
LEPROSY Figure 15-13 LEPROSY Clinical spectrum of leprosy, comparing Ridley-Jopling and World Health Organization (WHO) classifications. More about this image found in LEPROSY Clinical spectrum of leprosy, comparing Ridley-Jopling and World H...
Images
Figure 15-19
Published: 01 September 2024
TUBERCULOID LEPROSY Figure 15-19 TUBERCULOID LEPROSY Periadnexal epithelioid cell and focally granulomatous infiltrate. More about this image found in TUBERCULOID LEPROSY Periadnexal epithelioid cell and focally granulomatous...
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Figure 15-14
Published: 01 September 2024
TUBERCULOID LEPROSY Figure 15-14 TUBERCULOID LEPROSY Typical hypopigmented trunk skin lesions. (Courtesy of the CDC PHIL) More about this image found in TUBERCULOID LEPROSY Typical hypopigmented trunk skin lesions. (Courtesy of...
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Figure 15-21
Published: 01 September 2024
LEPROMATOUS LEPROSY Figure 15-21 LEPROMATOUS LEPROSY Medium-power view of diffuse dermal foamy macrophage infiltrate. More about this image found in LEPROMATOUS LEPROSY Medium-power view of diffuse dermal foamy macrophage i...
Images
Figure 15-20
Published: 01 September 2024
LEPROMATOUS LEPROSY Figure 15-20 LEPROMATOUS LEPROSY Spared “Grenz zone” separates the foamy macrophage infiltrate from the epidermis. More about this image found in LEPROMATOUS LEPROSY Spared “Grenz zone” separates the foamy macrophage inf...
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Figure 15-18
Published: 01 September 2024
TUBERCULOID LEPROSY Figure 15-18 TUBERCULOID LEPROSY Scant perineural mononuclear inflammatory infiltrate. (Courtesy of Dr. J. D. Ruiz, University of Antioquia, Medellín, Colombia) More about this image found in TUBERCULOID LEPROSY Scant perineural mononuclear inflammatory infiltrate. ...
Images
Figure 15-17
Published: 01 September 2024
TUBERCULOID LEPROSY Figure 15-17 TUBERCULOID LEPROSY There is a prominent perineural lymphocyte and epithelioid histiocyte infiltrate. (Courtesy of Dr. L. Tapia V, University of Antioquia, Medellín, Colombia) More about this image found in TUBERCULOID LEPROSY There is a prominent perineural lymphocyte and epithel...
Images
Figure 15-16
Published: 01 September 2024
ERYTHEMA NODOSUM LEPROSUM Figure 15-16 ERYTHEMA NODOSUM LEPROSUM Also known as type 2 leprosy reaction, there are new and painful, nodular skin lesions in an individual with lepromatous leprosy. (Courtesy of the CDC PHIL) More about this image found in ERYTHEMA NODOSUM LEPROSUM Also known as type 2 leprosy reaction, there are...
Images
Figure 15-22
Published: 01 September 2024
LEPROMATOUS LEPROSY Figure 15-22 LEPROMATOUS LEPROSY High-power view shows a dermal infiltrate of foamy macrophages containing intracellular blue-gray material, corresponding to abundant mycobacteria (so-called Virchow cells). More about this image found in LEPROMATOUS LEPROSY High-power view shows a dermal infiltrate of foamy mac...
Images
Figure 15-15
Published: 01 September 2024
LEPROMATOUS LEPROSY Figure 15-15 LEPROMATOUS LEPROSY Typical infiltrative lesions on the face and hand. Note the early leonine or lion-like facial features, with prominent skin induration and furrowed creases (A); diffusely infiltrated and grossly thickened digits (B). (Courtesy of the CDC PHIL) More about this image found in LEPROMATOUS LEPROSY Typical infiltrative lesions on the face and hand. Not...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-15
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
...) genes TAP1 and TAP2 (transporter associated with antigen processing) genes TNFα (tumor necrosis factor alpha) gene VDR (vitamin D receptor) gene PARK2 and PACRG (parkin co-regulated) genes Early onset leprosy Low lymphotoxin α-producing allele Table 15-2 TYPE AND CHARACTERISTICS OF NECROTIZING...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-28
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... and unique interaction between parasite virulence and host immune factors, which determine the nature of the inflammatory response, number of parasitic organisms, and extent of disease dissemination ( fig. 28-4 ). The disease is similar to leprosy in that the spectrum of histologic findings ranges from...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-09
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
.... avium-intracellulare b Gut, lymphoid tissue, bone marrow + + Other non-TB mycobacteria, except M. ulcerans Multiorgan Leprosy Skin, nerves + + BCG infection Skin, systemic + Fungi Aspergillus spp Lung, brain Blastomyces...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-24
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
..., mycobacteria (tuberculosis or leprosy), and parasites, as well as neoplasms such as primary cutaneous malignancies (epithelial, hematolymphoid, and mesenchymal tumors, including lymphoma and Kaposi sarcoma) and skin metastases. The most frequently implicated fungal pathogens in this neglected tropical disease...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-21
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... are not detected, the microscopic changes may additionally suggest the possibility of other granulomatous infections (such as tuberculosis, leprosy, and other mycobacterial lesions), especially in skin lesions. In the lung, noninfectious granulomatous disorders such as sarcoidosis and granulomatosis...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 12
Published: 01 August 2022
10.55418/9781933477220-11
ISBN-10: 1-933477-22-9
ISBN: 978-1-933477-22-0
... . Xanthogranulomatous orchitis with scrotal fistulas . Int J Urol   2004 ; 11 : 686 - 8 . 270. Grabstald   H , Swan   LL . Genitourinary lesions in leprosy, with special reference to the problem of atrophy of the testes . J Am Med Assoc   1952 ; 119 : 1287 - 91 . 271. McClure   J...
Images
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 10
Published: 01 January 2022
10.55418/9781933477183-4
ISBN-10: 1-933477-18-0
ISBN: 978-1-933477-18-3
.... leprosy M. aviumintracellulare Protozoa Toxoplasma gondii (toxoplasmosis) ( 113 ) Leishmaniasis ( 114 , 115 ) Parasites Schistosomiasis Giardia in the GI tract ( 122 ) Fungal Infections Aspergillus Candida Cryptococcus...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 10
Published: 01 January 2022
10.55418/9781933477183-8
ISBN-10: 1-933477-18-0
ISBN: 978-1-933477-18-3
... , Wang   Z , Bao   F , et al . Evaluation of prospective HLA-B*13:01 screening to prevent Dapsone hypersensitivity syndrome in patients with leprosy . JAMA Dermatol   2019 ; 155 : 666 – 72 . 10. Hughes   AR , Spreen   WR , Mosteller   M , et al . Phar-macogenetics...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 10
Published: 01 January 2022
10.55418/9781933477183-1
ISBN-10: 1-933477-18-0
ISBN: 978-1-933477-18-3
...  Tuberculosis  Leprosy  AIDS (can be Bartonella related)  Systemic lupus erythematosus Malnutrition Medications  Oral contraceptives  Androgens  Azathioprine Other  Pregnancy  Chronic renal failure Table 1-16 POTENTIAL DIAGNOSES TO EXCLUDE IN AN ALMOST NORMAL LIVER...