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Images
Published: 01 December 2024
CAROTID BODY PARAGANGLIOMA Figure 9-20 CAROTID BODY PARAGANGLIOMA Areas of sclerosis encroach on the tumor capsule and tumor blood vessels. The presence of hemosiderin suggests repeated ischemia and infarction as possible factors contributing to the development of sclerosis in this case. More about this image found in CAROTID BODY PARAGANGLIOMA Areas of sclerosis encroach on the tumor capsul...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-09
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... is associated with hemosiderin deposition, suggesting that ischemia or hypoxic signaling contribute to its development ( fig. 9-20 ). CAROTID BODY PARAGANGLIOMA Figure 9-20 CAROTID BODY PARAGANGLIOMA Areas of sclerosis encroach on the tumor capsule and tumor blood vessels. The presence of hemosiderin...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-04
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... and degenerative change in capsular vessels (capsular “arteriopathy”) has been reported, suggesting that focal hyperplasia may be a response to localized ischemia ( 11 ). Also, sporadic nodular adrenocortical disease may be associated with hypertension. Few studies have addressed the molecular characteristics...
Images
Published: 01 September 2024
ENTEROHEMORRHAGIC E. COLI (EHEC) INFECTION Figure 13-7 ENTEROHEMORRHAGIC E. COLI (EHEC) INFECTION Colon biopsies of EHEC infection show prominent surface epithelial degeneration, lamina propria red blood cell extravasation, and isolated mucosal microthrombi (A,B), as well as crypt withering, ulceration, and submucosal edema with red cell extravasation (C). Some of these microscopic features may be indistinguishable from localized or regional acute ischemia. More about this image found in ENTEROHEMORRHAGIC E. COLI (EHEC) INFECTION Colon biopsies...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-13
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
..., particularly Clostridioides difficile and, less often, Klebsiella oxytoca ( 33 ). Noninfectious considerations include primary regional or localized ischemia, as well as drugs such as nonsteroidal anti-inflammatory drugs (NSAIDs). ENTEROHEMORRHAGIC E. COLI (EHEC) INFECTION Figure 13...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-09
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... organ risk factors include a long cold ischemia time, reperfusion injury, delayed graft function, biopsy proven acute rejection, implantation of a ureteric stent at the time of transplant, and (most importantly) the type of immune suppressive therapy used. Additionally, coinfection with BKV and CMV...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-21
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... The pathologic hallmark of mucormycosis, irrespective of the site, is angioinvasion and obstruction of blood vessels by fungal organisms; this leads to secondary thrombosis, ischemia, and hemorrhagic or coagulative necrosis of affected tissues ( fig. 21-38 ) ( 12 ). The associated inflammatory infiltrate varies...
Images
Published: 15 November 2023
THROMBOTIC THROMBOCYTOPENIA PURPURA Figure 6-17 THROMBOTIC THROMBOCYTOPENIA PURPURA Circumferential subepicardial mottling (diffuse and coalescing petechial hemorrhages) is seen, a result of diffuse ischemia/infarction of the myocardium in the setting of thrombotic thrombocytopenia purpura. More about this image found in THROMBOTIC THROMBOCYTOPENIA PURPURA Circumferential subepicardial mottling...
Images
Published: 15 November 2023
PAPILLARY FIBROELASTOMA Figure 40-4 PAPILLARY FIBROELASTOMA Left: PFE (yellow arrow) arising from the closing edge of the anterior mitral leaflet. Right: PFE (yellow arrow) arising from the aortic surface of the right aortic valve cusp, immediately adjacent to the right coronary ostium (black ar... More about this image found in PAPILLARY FIBROELASTOMA Left: PFE (yellow arrow) arising from the closing ...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch29
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... S , et al . A pilot study of protein microarray for simultaneous analysis of 274 cytokines between abdominal aortic aneurysm and normal aorta . Angiology 2019 ; 70 : 830 - 7 . 20. Ahmad DS , Sahak K , Lazenby AJ , Bhat I . Chronic mesenteric ischemia and gastric...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 18
Published: 01 January 2024
10.55418/9781933477367-15
ISBN-10: 1-933477-36-9
ISBN: 978-1-933477-36-7
... cancer: ASCO/CAP guideline update . J Clin Oncol 2020 ; 38 : 1346 - 66 . 2. Li X , Deavers MT , Guo M , et al . The effect of prolonged cold ischemia time on estrogen receptor immunohistochemistry in breast cancer . Mod Pathol 2013 ; 26 : 71 - 8 . 3. Goldstein NS...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch07
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... ischemia and sudden cardiac death . Int J Legal Med 2016 ; 130 : 1265 - 80 . 17. Barranco R , Ventura F . Immunohistochemistry in the detection of early myocardial infarction: systematic review and analysis of limitations because of autolysis and putrefaction . Appl Immunohistochem...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch06
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... and coalescing petechial hemorrhages) is seen, a result of diffuse ischemia/infarction of the myocardium in the setting of thrombotic thrombocytopenia purpura. THROMBOTIC THROMBOCYTOPENIA PURPURA Figure 6-18 THROMBOTIC THROMBOCYTOPENIA PURPURA Fibrin-rich thrombi (black asterisk) are seen throughout the small...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch39
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
..., or pacemaker insertion, or experience a thromboembolic event or protein-losing enteropathy. The majority of congenital coronary artery anomalies are asymptomatic and clinically benign. However, some become symptomatic due to myocardial ischemia or infarction, mitral regurgitation, heart failure...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch08
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... of small particles from mural thrombi may be asymptomatic, embolization of larger fragments often leads to symptomatic ischemia or infarction, and may affect systemic organs (e.g., brain, heart). Thromboemboli are observed histologically at autopsy in about a third of cases but are apparent clinically...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch04
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
.... This is the cellular response to various forms of injury that cause energy depletion or membrane damage ( 11 ). Insults include hypoxia, ischemia, reperfusion, toxins, and inflammation. Membrane dysfunction leads to myocyte swelling and eventual death. Oncosis elicits an exudative inflammatory response; acute...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch25
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... are acute ischemia, scars, and cardiomegaly. Heart failure is known to increase the risk for ventricular tachyarrhythmias, regardless of the cause. In a proportion of patients with fatal ventricular arrhythmias in the absence of cardiomyopathy or ischemic heart disease, there are underlying mutations in ion...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch50
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... or lower extremities ( 4 , 5 , 8 ). Prolapse into the coronary arteries by lesions on the mitral or aortic valve can result in ischemia, myocardial infarction, and sudden death ( 6 , 11 , 12 ). About a third of patients present with inflammatory symptoms, including fever, malaise, and elevated serum acute...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch33
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
..., the effects on the liver are minimal. Mesenteric arterial thrombosis is a much more common cause of mesenteric ischemia than venous thrombosis. It accounts for 5 to 20 percent of cases of mesenteric ischemia and acute bowel infarction. Acute mesenteric vein thrombosis causes intestinal infarcts...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch11
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... thrombotic endocarditis and other cardiac sources of embolism in cancer patients with cerebral ischemia . Am J Cardiol 2006 ; 97 : 894 - 8 . 15. Biller J , Challa VR , Toole JF , Howard VJ . Non-bacterial thrombotic endocarditis. A neurologic perspective of clinicopathologic...
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