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Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 22
Published: 01 June 2025
10.55418/9781933477619-4
ISBN: 978-1-933477-61-9
... cells with interstitial hemorrhage ( fig. 4-55B,C ) ( 189 ). The giant cells have abundant cytoplasm and contain up to 100 nuclei ( fig. 4-55D ). Occasional mitoses may be seen. Metaplastic bone is present in a third of cases but is not a prominent feature ( 185 ). Differential Diagnosis. Kaposi...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-02
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... cords of cells usually seen in hyperplasia of eutopic or heterotopic adrenal cortex. Occasionally, there are interstitial adipocytes. TESTICULAR ADRENAL REST TUMOR IN A PATIENT WITH SALT-LOSING FORM OF 21-HYDROXYLASE DEFICIENCY Figure 2-15 TESTICULAR ADRENAL REST TUMOR IN A PATIENT WITH SALT-LOSING...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-01
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... mature adipocytes. This has been referred to as lipomatous metaplasia. Focal Lymphocytic Infiltration. Small interstitial or perivenous foci of lymphocytes and occasional plasma cells are a frequent incidental finding in the adrenal cortex and medulla. They are most common in elderly patients...
Images
Figure 4-13
Published: 01 September 2024
ADENOVIRUS PNEUMONITIS Figure 4-13 ADENOVIRUS PNEUMONITIS Interstitial inflammation, edema, focal hemorrhage, and numerous typical “smudge cells,” are visible at low (A) and high power (B). More about this image found in ADENOVIRUS PNEUMONITIS Interstitial inflammation, edema, focal hemorrhage,...
Images
Figure 9-12
Published: 01 September 2024
LYMPHOID INTERSTITIAL PNEUMONITIS (LIP) Figure 9-12 LYMPHOID INTERSTITIAL PNEUMONITIS (LIP) A: Chest computerized tomography (CT) scan showing widespread nodularity. B: There is a diffuse and nodular lymphocytic infiltration. C: Peribronchial and perivascular lymphocytic aggregates are seen More about this image found in LYMPHOID INTERSTITIAL PNEUMONITIS (LIP) A: Chest computerized tomography (...
Images
Figure 4-3
Published: 01 September 2024
INFLUENZA INFECTION OF THE LUNG Figure 4-3 INFLUENZA INFECTION OF THE LUNG Intra-alveolar edema and hemorrhage (A), and interstitial mononuclear inflammatory cell infiltration (B) are seen. More about this image found in INFLUENZA INFECTION OF THE LUNG Intra-alveolar edema and hemorrhage (A), a...
Images
Figure 12-33
Published: 01 September 2024
MYCOPLASMA PNEUMONIAE PNEUMONIA Figure 12-33 MYCOPLASMA PNEUMONIAE PNEUMONIA Chest X-ray shows patchy interstitial infiltrates and consolidation. (Courtesy of the CDC PHIL) More about this image found in MYCOPLASMA PNEUMONIAE PNEUMONIA Chest X-ray shows patchy ...
Images
Figure 4-20
Published: 01 September 2024
HEMORRHAGIC FEVER WITH RENAL SYNDROME (HFRS) Figure 4-20 HEMORRHAGIC FEVER WITH RENAL SYNDROME (HFRS) The kidney shows mild interstitial edema, tubular epithelial degeneration, congestion, and focal early hemorrhage. (Courtesy of the CDC IDPB) More about this image found in HEMORRHAGIC FEVER WITH RENAL SYNDROME (HFRS) The kidney shows mild interst...
Images
Figure 7-4
Published: 01 September 2024
MENINGOCOCCAL (BACTERIAL) MYOCARDITIS Figure 7-4 MENINGOCOCCAL (BACTERIAL) MYOCARDITIS A: There is a pronounced interstitial neutrophil infiltrate in a patient with meningococcemia. B: Red Neisseria meningitidis cytoplasmic positivity is seen on immunohistochemistry in many More about this image found in MENINGOCOCCAL (BACTERIAL) MYOCARDITIS A: There is a pronounced interstitia...
Images
Figure 11-9
Published: 01 September 2024
HISTOLOGY OF MENINGOCOCCEMIA Figure 11-9 HISTOLOGY OF MENINGOCOCCEMIA A: Adrenal gland with prominent hemorrhage and focal necrosis. B: Lung showing mild interstitial edema and early intra-alveolar hemorrhage. C: Heart with myocarditis demonstrating striking neutrophil infiltration. (All More about this image found in HISTOLOGY OF MENINGOCOCCEMIA A: Adrenal gland with prominent hemorrhage an...
Images
Figure 4-21
Published: 01 September 2024
HANTAVIRUS CARDIOPULMONARY SYNDROME (HCPS) Figure 4-21 HANTAVIRUS CARDIOPULMONARY SYNDROME (HCPS) Lung tissue with intraalveolar and interstitial edema, early hyaline membrane formation, congestion, and minimal septal lymphocyte infiltration (A,B). The spleen reveals scattered prominent More about this image found in HANTAVIRUS CARDIOPULMONARY SYNDROME (HCPS) Lung tissue with intraalveolar ...
Images
Figure 9-19
Published: 01 September 2024
HIV-ASSOCIATED NEPHROPATHY (HIVAN) Figure 9-19 HIV-ASSOCIATED NEPHROPATHY (HIVAN) A: Grossly enlarged kidney. B: Collapsing glomerulus with hypertrophied epithelial cells. C: Glomerular sclerosis demonstrated with a periodic acid methenamine (PAM) silver stain. D: Interstitial chronic More about this image found in HIV-ASSOCIATED NEPHROPATHY (HIVAN) A: Grossly enlarged kidney. B: Collaps...
Images
Figure 9-45
Published: 01 September 2024
BKV CYTOPATHIC EFFECT (SO-CALLED DECOY CELLS) Figure 9-45 BKV CYTOPATHIC EFFECT (SO-CALLED DECOY CELLS) Renal parenchyma with focal interstitial mononuclear (lymphohistiocytic and plasma cell) inflammation and epithelial cells. (Courtesy of Dr. L. F. Arias, University of Antioquia, Medellín More about this image found in BKV CYTOPATHIC EFFECT (SO-CALLED DECOY CELLS) Renal parenchyma with focal ...
Images
Figure 4-10
Published: 01 September 2024
PULMONARY COVID-19 Figure 4-10 PULMONARY COVID-19 A: Initial changes show some intra-alveolar fibrin with focal early hyaline membrane formation, scattered intra-alveolar red blood cells, and focal mild interstitial lymphocyte infiltration. B: Low-power view of patchy intra-alveolar fibrin More about this image found in PULMONARY COVID-19 A: Initial changes show some intra-alveolar fibrin with...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-04
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... Exacerbation of chronic obstructive pulmonary disease (COPD), congestive heart failure, and asthma Pneumonia and death Diffuse alveolar damage (hyaline membranes), interstitial fibrosis, fibrin thrombi, peribronchial inflammation Sometimes “smudge cells,” often no viral inclusions 79 - 81 Primarily...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-09
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
...-CD8 encephalitis (HIV-CD8E) Brain and spinal cord + Vacuolar myelopathy of spinal cord Spinal cord Lymphoid interstitial pneumonia (LIP) b Lung Wasting syndrome b Systemic; gelatinous transformation of bone marrow HIV-associated nephropathy (HIVAN) Kidney...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-10
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... in numerous organs and include interstitial pneumonitis, myocarditis, lymph node sinus histiocytosis, and interstitial nephritis. The gastrointestinal tract may reveal mucosal hemorrhages and there may be renal tubular necrosis. Immunohistochemical assays demonstrate Lassa virus antigens in endothelial cells...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-07
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... Distribution Focal, confluent, or diffuse Extent Mild, moderate, or severe Cell type Lymphocytic, neutrophilic, eosinophilic, granulomatous, giant cell, or mixed Fibrosis Distribution Subendocardial or interstitial Extent Mild, moderate, or severe Type Perivascular, patchy...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-11
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... and focal necrosis. B: Lung showing mild interstitial edema and early intra-alveolar hemorrhage. C: Heart with myocarditis demonstrating striking neutrophil infiltration. (All: courtesy of the CDC IDPB) SKIN BIOPSY IN PATIENT WITH MENINGOCOCCEMIA Figure 11-10 SKIN BIOPSY IN PATIENT WITH MENINGOCOCCEMIA...
Book Chapter

Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-23
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
..., anorexia, and respiratory symptoms Can be associated with hepatosplenomegaly, skin and oral lesions, progressing to involve meninges Lung infiltrates can show interstitial, miliary, or diffuse reticulonodular pattern LIFE CYCLE OF HISTOPLASMA SPP Figure 23-1 LIFE CYCLE OF HISTOPLASMA...