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Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 18
Published: 01 January 2024
10.55418/9781933477367-15
ISBN-10: 1-933477-36-9
ISBN: 978-1-933477-36-7
... mastectomy at the time of therapeutic mastectomy, as discussed above. The surgical procedure is intended to remove all breast tissue; however, as noted in chapter 1 , breast tissue can extend up into the axilla and interdigitate through the pectoralis fascia, thus depending on individual anatomy...
Images
DIFFUSE ISLET OF LANGERHANS  Diffuse islets (left) from the posteroinferior...
Published: 01 March 2023
DIFFUSE ISLET OF LANGERHANS Figure 1-17 DIFFUSE ISLET OF LANGERHANS Diffuse islets (left) from the posteroinferior head are trabecular and less clearly defined from the adjacent acinar epithelium, relative to the compact islets. Interdigitation of islet cells and acinar cells (right) can be confu... More about this image found in DIFFUSE ISLET OF LANGERHANS Diffuse islets (left) from the posteroinferior...
Images
HIGH-GRADE SQUAMOUS INTRAEPITHELIAL LESION WITH PAGETOID SPREAD  Left: Nest...
Published: 01 February 2023
HIGH-GRADE SQUAMOUS INTRAEPITHELIAL LESION WITH PAGETOID SPREAD Figure 5-16 HIGH-GRADE SQUAMOUS INTRAEPITHELIAL LESION WITH PAGETOID SPREAD Left: Nests of neoplastic cells interdigitate with the normal squamous epithelium, mimicking extramammary Paget disease. Right: Staining for p63 confirms squ... More about this image found in HIGH-GRADE SQUAMOUS INTRAEPITHELIAL LESION WITH PAGETOID SPREAD Left: Nest...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 15
Published: 01 March 2023
10.55418/9781933477275-01
ISBN-10: 1-933477-27-X
ISBN: 978-1-933477-27-5
... and sharply demarcated from the surrounding acinar epithelium. DIFFUSE ISLET OF LANGERHANS Figure 1-17 DIFFUSE ISLET OF LANGERHANS Diffuse islets (left) from the posteroinferior head are trabecular and less clearly defined from the adjacent acinar epithelium, relative to the compact islets. Interdigitation...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 15
Published: 01 March 2023
10.55418/9781933477275-11
ISBN-10: 1-933477-27-X
ISBN: 978-1-933477-27-5
.... The interface between the neoplasm and the pancreas is irregular, with strands of neoplastic cells gently interdigitating among islands of normal-appearing parenchyma ( fig. 11-15A ). This pattern of infiltration is distinctive, as there is usually no stromal reaction ( 14 ), and nests of neoplastic cells...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 14
Published: 01 February 2023
10.55418/9781933477268-5
ISBN-10: 1-933477-26-1
ISBN: 978-1-933477-26-8
... staining, localized to suprabasal nuclei only, sparing the basal layer (D). Another rare variant is pagetoid HSIL. Here, nests of neoplastic squamous epithelium interdigitate with, rather than replace, the normal squamous mucosal epithelium ( fig. 5-16 ) ( 44 ). HIGH-GRADE SQUAMOUS INTRAEPITHELIAL...
Images
<span class="search-highlight">INTERDIGITATING</span> DENDRITIC CELL TUMOR OF TESTIS  Left: Large, epithelioid to...
Published: 01 August 2022
INTERDIGITATING DENDRITIC CELL TUMOR OF TESTIS Figure 9-37 INTERDIGITATING DENDRITIC CELL TUMOR OF TESTIS Left: Large, epithelioid to spindled tumor cells with ill-defined, lightly eosinophilic cytoplasm and vesicular, sometimes convoluted nuclei are admixed with a predominantly lymphocytic infla... More about this image found in INTERDIGITATING DENDRITIC CELL TUMOR OF TESTIS Left: Large, epithelioid to...
Images
SERTOLI CELLS  Electron micrograph of Sertoli cells shows intricate, interd...
Published: 01 August 2022
SERTOLI CELLS Figure 2-28 SERTOLI CELLS Electron micrograph of Sertoli cells shows intricate, interdigitating cytoplasmic processes. Cell at top left has numerous lipid droplets and annulate lamellae. More about this image found in SERTOLI CELLS Electron micrograph of Sertoli cells shows intricate, interd...
Images
SERTOLI CELL TUMOR, NOS  An electron micrograph shows round nuclei with dis...
Published: 01 August 2022
SERTOLI CELL TUMOR, NOS Figure 6-74 SERTOLI CELL TUMOR, NOS An electron micrograph shows round nuclei with dispersed chromatin, parallel arrays of smooth endoplasmic reticulum, multiple round mitochondria, a large lipid droplet, and interdigitating cytoplasmic processes (right). (Courtesy of Dr. ... More about this image found in SERTOLI CELL TUMOR, NOS An electron micrograph shows round nuclei with dis...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 13
Published: 01 November 2022
10.55418/9781933477251-3
ISBN-10: 1-933477-25-3
ISBN: 978-1-933477-25-1
... separates them from the interstitial stroma. Microvilli are present at the apical portions of the cells ( 20 , 21 ), and their number and length are increased in actively functioning cells ( 19 ). Cell membranes of adjacent cells interdigitate in a complex fashion and are joined by junctional complexes...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 13
Published: 01 November 2022
10.55418/9781933477251-4
ISBN-10: 1-933477-25-3
ISBN: 978-1-933477-25-1
... and interdigitating blunt cytoplasmic processes with poorly developed cell junctions. The sustentacular cells are in close proximity to the chromaffin cells. They have oval indented nuclei and thin elongated cytoplasmic processes ( 55 ). These cells partially surround the chromaffin cells without the interposition...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 12
Published: 01 August 2022
10.55418/9781933477220-09
ISBN-10: 1-933477-22-9
ISBN: 978-1-933477-22-0
... cells are antigen-presenting, immune-accessory cells found in lymphoid organs and less commonly in other sites ( 131 ). They initiate adaptive immune responses and, based on unique immunohistochemical characteristics, are classified into four types: follicular, interdigitating, indeterminate...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 12
Published: 01 August 2022
10.55418/9781933477220-02
ISBN-10: 1-933477-22-9
ISBN: 978-1-933477-22-0
... a “nurturing” function for the maturing germ cell population, are also phagocytic and may contain fragments of degenerated germ cells. SERTOLI CELLS Figure 2-28 SERTOLI CELLS Electron micrograph of Sertoli cells shows intricate, interdigitating cytoplasmic processes. Cell at top left has numerous lipid...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 12
Published: 01 August 2022
10.55418/9781933477220-06
ISBN-10: 1-933477-22-9
ISBN: 978-1-933477-22-0
... CELL TUMOR, NOS Figure 6-74 SERTOLI CELL TUMOR, NOS An electron micrograph shows round nuclei with dispersed chromatin, parallel arrays of smooth endoplasmic reticulum, multiple round mitochondria, a large lipid droplet, and interdigitating cytoplasmic processes (right). (Courtesy of Dr. R...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 12
Published: 01 August 2022
10.55418/9781933477220-04
ISBN-10: 1-933477-22-9
ISBN: 978-1-933477-22-0
... complexes are identified, with well-defined desmosomes, as adjacent cells form abortive extracellular lumens with short projecting microvilli ( 86 , 235 , 325 ). Complex interdigitating cell membranes may be identified ( 326 ). Seminomas displaying epithelial differentiation on ultrastructural examination...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 12
Published: 01 August 2022
10.55418/9781933477220-08
ISBN-10: 1-933477-22-9
ISBN: 978-1-933477-22-0
... testis . Urology   2009 ; 73 : 1423.e1429 - 1412 . 525. Nistal   M , Gonzalez-Peramato   P , Serrano   A , Reyes-Mugica   M , Cajaiba   MM . Primary intratesticular spindle cell tumors: interdigitating dendritic cell tumor and inflammatory myofibroblastic tumor . Int J Surg...
Images
<span class="search-highlight">INTERDIGITATING</span> DENDRITIC CELL SARCOMA  The neoplastic cells are arranged i...
Published: 01 September 2021
INTERDIGITATING DENDRITIC CELL SARCOMA Figure 3-171 INTERDIGITATING DENDRITIC CELL SARCOMA The neoplastic cells are arranged in fascicles. (Courtesy of Dr. J. Hornick, Boston, MA) More about this image found in INTERDIGITATING DENDRITIC CELL SARCOMA The neoplastic cells are arranged i...
Images
<span class="search-highlight">INTERDIGITATING</span> DENDRITIC CELL SARCOMA  S-100 protein staining, as seen her...
Published: 01 September 2021
INTERDIGITATING DENDRITIC CELL SARCOMA Figure 3-172 INTERDIGITATING DENDRITIC CELL SARCOMA S-100 protein staining, as seen here, in the absence of CD1a and langerin, is typical of this entity. (Courtesy of Dr. J. Hornick, Boston, MA) More about this image found in INTERDIGITATING DENDRITIC CELL SARCOMA S-100 protein staining, as seen her...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 9
Published: 01 November 2021
10.55418/9781933477176-1
ISBN-10: 1-933477-17-2
ISBN: 978-1-933477-17-6
... are helpful in the differential diagnosis: 1) bilaterality, the presence of nephrogenic rests, or both strongly favors nephroblastoma; 2) an interdigitating, irregular border favors congenital mesoblastic nephroma; cellular congenital mesoblastic nephroma often has a sharp, pushing border, similar...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 7
Published: 01 September 2021
10.55418/9781933477121-3
ISBN-10: 1-933477-12-1
ISBN: 978-1-933477-12-1
... to be distinguished from indeterminate dendritic cell histiocytosis, malignant histiocytoses (histiocytic, follicular dendritic cell, and interdigitating dendritic cell sarcoma), and deposits of acute leukemia ( 508 ). Differentiation from Langerhans cell sarcoma, the malignant counterpart of LCH, may be more...