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Images
Published: 01 September 2024
ENTEROVIRUS MYOCARDITIS Figure 7-2 ENTEROVIRUS MYOCARDITIS A scant lymphocyte infiltrate and myocyte injury (A) are seen. Lymphocytic infiltration can be patchy (C), making detection on endomyocardial biopsy difficult. Confirmatory enterovirus immunohistochemistry (B) demonstrates red cytoplasmic... More about this image found in ENTEROVIRUS MYOCARDITIS A scant lymphocyte infiltrate and myocyte injury (...
Images
Published: 01 September 2024
INFLUENZA B VIRUS MYOCARDITIS Figure 7-3 INFLUENZA B VIRUS MYOCARDITIS At low (A) and high power (B), a discrete perivascular lymphocyte infiltrate and associated myocyte injury are seen. Immunohistochemical staining did not demonstrate influenza B virus in the myocardium, although it was demonst... More about this image found in INFLUENZA B VIRUS MYOCARDITIS At low (A) and high power (B), a discrete pe...
Images
Published: 01 September 2024
ROCKY MOUNTAIN SPOTTED FEVER Figure 14-35 ROCKY MOUNTAIN SPOTTED FEVER Histopathology of renal (A), lung (B), and brain white matter (C). There are predominantly mononuclear cell inflammatory cell infiltrates and foci of endothelial injury with erythrocyte extravasation. Note the early microglial... More about this image found in ROCKY MOUNTAIN SPOTTED FEVER Histopathology of renal (A), lung (B), and br...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-07
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
...VIRAL MYOCARDITIS General Considerations, Including Etiology and Synonyms Myocarditis, inflammation of the heart muscle frequently associated with myocyte injury and cardiac dysfunction, can have various causes, including viral infection. An integral part of the definitive diagnosis...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-05
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... injury from a low replicator, to 90 percent in babies born to a high replicator mother ( 6 , 7 ). HCV is most often spread through IV drug use and percutaneous blood exposure. HDV is parenterally and sexually spread, but requires the presence of HBV infection for replication. The risk of developing...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-16
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... endocarditis requires initial trauma to the surface endocardium in order for the etiologic organisms to establish themselves in the endocardial lining ( fig. 16-1 ) ( 4 ). This trauma can be due to inflammation as a result of degenerative changes or rheumatic heart disease, mechanical injury secondary...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-04
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... such as IL-1β, IL-6, IL-8, and TNFα, which may give rise to a cytokine storm in the host ( 4 ). The latter is characterized by the excessive production of proinflammatory cytokines and insufficient control of anti-inflammatory responses, with extensive tissue injury and death ( 5 ). As the influenza virus...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-10
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... phagocytic system; release of pro-inflammatory cytokines, chemokines, and growth factors; endothelial dysfunction; alterations in the immune system; endothelial injury with coagulopathy; and direct organ damage ( 7 ). Clinical Features Marburg virus infection has an incubation period ranging from a few days...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-03
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... ). Vaccines are known to confer protection by producing a vigorous T-cell–mediated neutralizing antibody response against the rabies G protein ( 15 ). Treatment of human exposure includes thorough cleaning of the injury site, with the administration of hyperimmune globulin and vaccination before any symptoms...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-27
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
...; includes cerebral malaria, acute respiratory distress, acute kidney injury, cardiovascular collapse, severe hemolysis (parasitemia >5%), hemoglobinuria, metabolic acidosis, hypoglycemia, and coagulation abnormalities Splenic rupture Can be caused by P. vivax Nephrotic syndrome Due...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-13
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... Similar to Shigella spp, with prominent mucosal neutrophil infiltration and occasional severe mucosal injury EAEC Acute nonmucoid, nonbloody/watery diarrhea, vomiting, abdominal pain, and low-grade fever Can be associated with chronic diarrhea, wasting, and postinfectious irritable bowel...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-21
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... the function of lung surfactant but do not invade tissue or cause pneumocyte or cell injury. In the alveoli, the trophic forms undergo cell wall remodeling and mating, and eventually form cysts. The latter are the infectious form of the organism, larger (8 to 10 μm) than the trophic forms and have a rigid cell...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-18
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... includes other venereal diseases such as syphilis and gonorrhea. In rectal involvement, the intense inflammation and chronic mucosal injury raises the possibility of chronic inflammatory bowel disease (especially ulcerative proctitis). Lymph node involvement in LGV suggests cat scratch disease...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-09
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... organ risk factors include a long cold ischemia time, reperfusion injury, delayed graft function, biopsy proven acute rejection, implantation of a ureteric stent at the time of transplant, and (most importantly) the type of immune suppressive therapy used. Additionally, coinfection with BKV and CMV...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-12
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... injury and ingestion are other potential transmission routes. Immunocompromised individuals are at high risk for infection, including those with HIV, lymphoma, or other malignancies, and those receiving treatment with corticosteroids or other immunosuppressive therapies (such as calcineurin inhibitors...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-14
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... mononuclear cell inflammatory cell infiltrates and foci of endothelial injury with erythrocyte extravasation. Note the early microglial nodule formation in the white matter. (Courtesy of the CDC IDPB) Immunohistochemical assays can be used to highlight the bacterial organisms. These are difficult to identify...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-15
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... procedures and spa treatments, and an increase in traumatic injuries ( 45 ). M. marinum, in particular, is associated with specific environmental activities, such as cleaning aquaria and fish tanks. Lesions caused by the M. avium/intracellulare complex, on the other hand, are associated...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-24
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... . 33. Faisal H , Radwan A , Ansari N . Primary pulmonary botryomycosis presenting with septic shock and acute lung injury . BMJ Case Rep 2011 ; 2011 . 34. Mathew M , Nayal B , Nagel B , Thomas J . Incidental renal botryomycosis in a nonfunctioning kidney...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch04
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... This represents one of the three microfocal types of chronic myocardial ischemic injury Lacy collagen meshwork, once occupied by myocytes Primarily subendocardial location The other two are myocytolysis and microscopic fibrosis, and both are also primarily subendocardial Interstitial cell necrosis...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch23
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... of the following: a. Elevated biomarker of cardiac injury b. EKG evidence of epimyocarditis 3. New regional wall motion abnormality on echocardiography, not otherwise explained, and ALL of the following: a. Clinical myocarditis b. Elevated biomarker of cardiac injury c. EKG evidence...
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