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Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch04
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... This represents one of the three microfocal types of chronic myocardial ischemic injury Lacy collagen meshwork, once occupied by myocytes Primarily subendocardial location The other two are myocytolysis and microscopic fibrosis, and both are also primarily subendocardial Interstitial cell necrosis...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch23
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... of the following: a. Elevated biomarker of cardiac injury b. EKG evidence of epimyocarditis 3. New regional wall motion abnormality on echocardiography, not otherwise explained, and ALL of the following: a. Clinical myocarditis b. Elevated biomarker of cardiac injury c. EKG evidence...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-06
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
...This chapter addresses the histopathologic changes associated with persistent melanocytic nevi presenting with repigmentation after prior surgery and nevi changing in response to nonsurgical mechanical trauma or biochemical injury, such as effects from cancer treatment. Knowledge of the effects...
Images
VALVULAR <span class="search-highlight">INJURY</span>  An elastic stain highlights loss of the valvular fibrosa (...
Published: 15 November 2023
VALVULAR INJURY Figure 12-9 VALVULAR INJURY An elastic stain highlights loss of the valvular fibrosa (atrialis), replaced by surface fibrin (white asterisk) and abrupt loss of the valvular elastica (white arrow). More about this image found in VALVULAR INJURY An elastic stain highlights loss of the valvular fibrosa (...
Images
HYPERTROPHIC CARDIOMYOPATHY: CHRONIC ISCHEMIC <span class="search-highlight">INJURY</span>  Sarcoplasmic vacuoliz...
Published: 15 November 2023
HYPERTROPHIC CARDIOMYOPATHY: CHRONIC ISCHEMIC INJURY Figure 15-11 HYPERTROPHIC CARDIOMYOPATHY: CHRONIC ISCHEMIC INJURY Sarcoplasmic vacuolization may be seen in the subendocardium of hearts with hypertrophic cardiomyopathy, as a result of chronic ischemic injury. More about this image found in HYPERTROPHIC CARDIOMYOPATHY: CHRONIC ISCHEMIC INJURY Sarcoplasmic vacuoliz...
Images
LYMPHOCYTIC MYOCARDITIS: MYOCYTE <span class="search-highlight">INJURY</span>  Interstitial lymphocytes surround ...
Published: 15 November 2023
LYMPHOCYTIC MYOCARDITIS: MYOCYTE INJURY Figure 22-6 LYMPHOCYTIC MYOCARDITIS: MYOCYTE INJURY Interstitial lymphocytes surround the myocytes, fragmenting and destroying them. Unlike ischemic injury, the infiltrate is primarily lymphocytic and the injured myocytes often still have nuclei, indicating... More about this image found in LYMPHOCYTIC MYOCARDITIS: MYOCYTE INJURY Interstitial lymphocytes surround ...
Images
GIANT CELL MYOCARDITIS: EXTENSIVE MYOCYTE <span class="search-highlight">INJURY</span>  There is extensive myocyt...
Published: 15 November 2023
GIANT CELL MYOCARDITIS: EXTENSIVE MYOCYTE INJURY Figure 22-23 GIANT CELL MYOCARDITIS: EXTENSIVE MYOCYTE INJURY There is extensive myocyte injury in association with the florid inflammatory infiltrate. More about this image found in GIANT CELL MYOCARDITIS: EXTENSIVE MYOCYTE INJURY There is extensive myocyt...
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RADIATION-MEDIATED <span class="search-highlight">INJURY</span>  Interstitial (pericellular-type) fibrosis (left)...
Published: 15 November 2023
RADIATION-MEDIATED INJURY Figure 23-9 RADIATION-MEDIATED INJURY Interstitial (pericellular-type) fibrosis (left) and scattered calcified, necrotic myocytes (arrows) (right) are identified. More about this image found in RADIATION-MEDIATED INJURY Interstitial (pericellular-type) fibrosis (left)...
Images
RADIATION-MEDIATED <span class="search-highlight">INJURY</span>  Extensive nodular calcification is seen througho...
Published: 15 November 2023
RADIATION-MEDIATED INJURY Figure 23-10 RADIATION-MEDIATED INJURY Extensive nodular calcification is seen throughout the left ventricle (endocardium and myocardium) in this patient who received radiotherapy for a thymoma. More about this image found in RADIATION-MEDIATED INJURY Extensive nodular calcification is seen througho...
Images
ABLATION <span class="search-highlight">INJURY</span>  Left: White scarring is seen grossly in this remote ablati...
Published: 15 November 2023
ABLATION INJURY Figure 23-11 ABLATION INJURY Left: White scarring is seen grossly in this remote ablation site (yellow arrow). Right: Histologically, there is scarring of the endocardium and myocardium in this region (Masson trichrome stain). More about this image found in ABLATION INJURY Left: White scarring is seen grossly in this remote ablati...
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PENETRATIVE <span class="search-highlight">INJURY</span>: GUNSHOT WOUND  This high-velocity weapon caused extensi...
Published: 15 November 2023
PENETRATIVE INJURY: GUNSHOT WOUND Figure 23-15 PENETRATIVE INJURY: GUNSHOT WOUND This high-velocity weapon caused extensive morcellation of the right and left ventricles. More about this image found in PENETRATIVE INJURY: GUNSHOT WOUND This high-velocity weapon caused extensi...
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BLUNT-FORCE <span class="search-highlight">INJURY</span>: MOTOR VEHICLE ACCIDENT  Right ventricular rupture occur...
Published: 15 November 2023
BLUNT-FORCE INJURY: MOTOR VEHICLE ACCIDENT Figure 23-16 BLUNT-FORCE INJURY: MOTOR VEHICLE ACCIDENT Right ventricular rupture occurred after a motor vehicle accident. More about this image found in BLUNT-FORCE INJURY: MOTOR VEHICLE ACCIDENT Right ventricular rupture occur...
Images
MYOCYTE <span class="search-highlight">INJURY</span>  Inflammation envelopes the myocytes, with associated scallo...
Published: 15 November 2023
MYOCYTE INJURY Figure 24-2 MYOCYTE INJURY Inflammation envelopes the myocytes, with associated scalloping of the sarcoplasmic membranes (black arrows). Fragments of myocytes are seen within the infiltrate. More about this image found in MYOCYTE INJURY Inflammation envelopes the myocytes, with associated scallo...
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ISCHEMIC <span class="search-highlight">INJURY</span>: SARCOPLASMIC STAINING  C4d (left) and C3d (right) immunofl...
Published: 15 November 2023
ISCHEMIC INJURY: SARCOPLASMIC STAINING Figure 24-9 ISCHEMIC INJURY: SARCOPLASMIC STAINING C4d (left) and C3d (right) immunofluorescent staining around the myocytes rather than the capillary staining of true AMR. More about this image found in ISCHEMIC INJURY: SARCOPLASMIC STAINING C4d (left) and C3d (right) immunofl...
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ACUTE ISCHEMIC <span class="search-highlight">INJURY</span>  This focus of myocyte necrosis (black arrow) in an e...
Published: 15 November 2023
ACUTE ISCHEMIC INJURY Figure 24-13 ACUTE ISCHEMIC INJURY This focus of myocyte necrosis (black arrow) in an endomyocardial biopsy is associated with nuclear loss and hypereosinophilia as well as contraction bands. More about this image found in ACUTE ISCHEMIC INJURY This focus of myocyte necrosis (black arrow) in an e...
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CHRONIC ISCHEMIC <span class="search-highlight">INJURY</span>  Underlying cardiac allograft vasculopathy may caus...
Published: 15 November 2023
CHRONIC ISCHEMIC INJURY Figure 24-14 CHRONIC ISCHEMIC INJURY Underlying cardiac allograft vasculopathy may cause chronic ischemic injury characterized by prominent sarcoplasmic vacuolization and interstitial (pericellular-type) fibrosis. More about this image found in CHRONIC ISCHEMIC INJURY Underlying cardiac allograft vasculopathy may caus...
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MODERATE CELL-MEDIATED REJECTION (GRADE 2R)  The lymphocytic infiltrate ext...
Published: 15 November 2023
MODERATE CELL-MEDIATED REJECTION (GRADE 2R) Figure 24-4 MODERATE CELL-MEDIATED REJECTION (GRADE 2R) The lymphocytic infiltrate extends beyond the perivascular territory into the interstitium and is associated with multifocal myocyte injury. Only a single focus of injury is shown here (black arrow... More about this image found in MODERATE CELL-MEDIATED REJECTION (GRADE 2R) The lymphocytic infiltrate ext...
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DILATED CARDIOMYOPATHY: PERIVASCULAR INFLAMMATION  Perivascular inflammatio...
Published: 15 November 2023
DILATED CARDIOMYOPATHY: PERIVASCULAR INFLAMMATION Figure 14-15 DILATED CARDIOMYOPATHY: PERIVASCULAR INFLAMMATION Perivascular inflammation that is either lymphocytic or a mixture of lymphocytes and eosinophils may be present in DCM and generally does not cause myocyte injury. This inflammation is... More about this image found in DILATED CARDIOMYOPATHY: PERIVASCULAR INFLAMMATION Perivascular inflammatio...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch24
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... a Histologic Hallmarks Cell-mediated 3-6 months T-lymphocyte infiltrates ± myocyte injury Antibody-mediated Days-years Complement deposition in capillary endothelium, endothelial cell swelling, intravascular mononuclear cells Graft vasculopathy Years Concentric intimal thickening...
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CARDIOTOXICITY: COCAINE  Cocaine-associated myocarditis, without definitive...
Published: 15 November 2023
CARDIOTOXICITY: COCAINE Figure 23-14 CARDIOTOXICITY: COCAINE Cocaine-associated myocarditis, without definitive myocyte injury in this instance. More about this image found in CARDIOTOXICITY: COCAINE Cocaine-associated myocarditis, without definitive...