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Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch12
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
...Table 12-1 RISK FACTORS FOR INFECTIVE ENDOCARDITIS Male sex Age >60 years Intravenous drug use Structural heart disease Poor dental hygiene Prosthetic cardiac device or leads Intravascular device Malignancy Immunosuppression Chronic hemodialysis Table 12-2...
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<span class="search-highlight">INFECTIVE</span> ENDOCARDITIS  <span class="search-highlight">Infective</span> endocarditis affects structurally abnorma...
Published: 15 November 2023
INFECTIVE ENDOCARDITIS Figure 12-5 INFECTIVE ENDOCARDITIS Infective endocarditis affects structurally abnormal (congenitally bicuspid) aortic valves. Left: Active native valve endocarditis (NVE), with vegetation (black asterisk) and cusp perforation (yellow asterisk), is seen. Right: Healed NVE... More about this image found in INFECTIVE ENDOCARDITIS Infective endocarditis affects structurally abnorma...
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<span class="search-highlight">INFECTIVE</span> ENDOCARDITIS: SUBACUTE (HEALING)  Left: At low power, the <span class="search-highlight">infecte</span>...
Published: 15 November 2023
INFECTIVE ENDOCARDITIS: SUBACUTE (HEALING) Figure 12-14 INFECTIVE ENDOCARDITIS: SUBACUTE (HEALING) Left: At low power, the infected valve is injured and inflamed, with shallow surface fibrin/vegetation. Right: At high power, the chronic nature of the inflammation is evident, along with organizat... More about this image found in INFECTIVE ENDOCARDITIS: SUBACUTE (HEALING) Left: At low power, the infecte...
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<span class="search-highlight">INFECTIVE</span> ENDOCARDITIS: WHIPPLE DISEASE  <span class="search-highlight">Infection</span> with <em>Tropheryma </em>...
Published: 15 November 2023
INFECTIVE ENDOCARDITIS: WHIPPLE DISEASE Figure 12-15 INFECTIVE ENDOCARDITIS: WHIPPLE DISEASE Infection with Tropheryma whipplei usually lacks exuberant acute inflammation, but instead has numerous plump histiocytes which are filled with the microorganism, as highlighted by PAS with diastase staining. More about this image found in INFECTIVE ENDOCARDITIS: WHIPPLE DISEASE Infection with Tropheryma ...
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MIXED PATTERN MYOCARDITIS: LYME MYOCARDITIS  Rickettsia <span class="search-highlight">infection</span> can produ...
Published: 15 November 2023
MIXED PATTERN MYOCARDITIS: LYME MYOCARDITIS Figure 22-17 MIXED PATTERN MYOCARDITIS: LYME MYOCARDITIS Rickettsia infection can produce a mixed inflammatory infiltrate containing lymphocytes, eosinophils, and neutrophils in varying proportion. More about this image found in MIXED PATTERN MYOCARDITIS: LYME MYOCARDITIS Rickettsia infection can produ...
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CYTOMEGALOVIRUS (CMV) <span class="search-highlight">INFECTION</span> OF THE CARDIAC ALLOGRAFT  Left: Viral cytop...
Published: 15 November 2023
CYTOMEGALOVIRUS (CMV) INFECTION OF THE CARDIAC ALLOGRAFT Figure 24-16 CYTOMEGALOVIRUS (CMV) INFECTION OF THE CARDIAC ALLOGRAFT Left: Viral cytopathic effect consisting of intranuclear inclusions is seen (black arrow). Right: CMV immunohistochemistry can help to confirm the viral pathogen (black ... More about this image found in CYTOMEGALOVIRUS (CMV) INFECTION OF THE CARDIAC ALLOGRAFT Left: Viral cytop...
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PERICARDIAL CONSTRICTION: WHIPPLE DISEASE  <span class="search-highlight">Infection</span> with Tropheryma whippl...
Published: 15 November 2023
PERICARDIAL CONSTRICTION: WHIPPLE DISEASE Figure 26-10 PERICARDIAL CONSTRICTION: WHIPPLE DISEASE Infection with Tropheryma whipplei will usually exhibits a neutrophilic and macrophage infiltrate (left) and PAS–D-positive microorganisms within the tissue macrophages (right). More about this image found in PERICARDIAL CONSTRICTION: WHIPPLE DISEASE Infection with Tropheryma whippl...
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HETEROTAXY SYNDROME: ASPLENIA-RELATED <span class="search-highlight">INFECTION</span>  <em>Streptococcus pneu</em>...
Published: 15 November 2023
HETEROTAXY SYNDROME: ASPLENIA-RELATED INFECTION Figure 39-50 HETEROTAXY SYNDROME: ASPLENIA-RELATED INFECTION Streptococcus pneumoniae meningitis, with multiple purulent exudates, was the cause of death in an infant. (Inferior aspect of brain.) More about this image found in HETEROTAXY SYNDROME: ASPLENIA-RELATED INFECTION Streptococcus pneu...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 18
Published: 01 January 2024
10.55418/9781933477367-02
ISBN-10: 1-933477-36-9
ISBN: 978-1-933477-36-7
... is not required. There is no increased risk of lymphoma associated with lymphocytic mastopathy ( 10 ). SYSTEMIC CONDITIONS Infections and inflammatory conditions that occur elsewhere in the body may also occur in the breast. The morphologic features of these lesions, when presenting in the breast, are similar...
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<span class="search-highlight">INFECTIVE</span> ENDOCARDITIS: COMPLICATIONS  A: Prosthetic valve dehiscence with ...
Published: 15 November 2023
INFECTIVE ENDOCARDITIS: COMPLICATIONS Figure 12-6 INFECTIVE ENDOCARDITIS: COMPLICATIONS A: Prosthetic valve dehiscence with early fistula formation into the aortic adventitia (yellow arrowhead) and annular abscess (yellow asterisk) complicating a tilting disc mechanical aortic valve. B: Splenic ... More about this image found in INFECTIVE ENDOCARDITIS: COMPLICATIONS A: Prosthetic valve dehiscence with ...
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<span class="search-highlight">INFECTIVE</span> ENDOCARDITIS: BACTERIAL STAINING  A: Hematoxylin and eosin (H&amp...
Published: 15 November 2023
INFECTIVE ENDOCARDITIS: BACTERIAL STAINING Figure 12-10 INFECTIVE ENDOCARDITIS: BACTERIAL STAINING A: Hematoxylin and eosin (H&E) staining reveals numerous basophilic bacterial colonies growing in clusters. B: Tissue Gram stain highlights the Gram-positive nature of these microorganisms, alt... More about this image found in INFECTIVE ENDOCARDITIS: BACTERIAL STAINING A: Hematoxylin and eosin (H&...
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<span class="search-highlight">INFECTIVE</span> ENDOCARDITIS: DEAD BACTERIAL STAINING  Bacteria typically lose th...
Published: 15 November 2023
INFECTIVE ENDOCARDITIS: DEAD BACTERIAL STAINING Figure 12-11 INFECTIVE ENDOCARDITIS: DEAD BACTERIAL STAINING Bacteria typically lose their basophilic staining pattern on H&E as they die (left); however, Grocott methenamine silver (GMS) stain frequently still highlights the structures (right).... More about this image found in INFECTIVE ENDOCARDITIS: DEAD BACTERIAL STAINING Bacteria typically lose th...
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<span class="search-highlight">INFECTIVE</span> ENDOCARDITIS: FUNGAL STAINING  A: A silver stain highlights numer...
Published: 15 November 2023
INFECTIVE ENDOCARDITIS: FUNGAL STAINING Figure 12-12 INFECTIVE ENDOCARDITIS: FUNGAL STAINING A: A silver stain highlights numerous black septate hyphae in this case of Aspergillus sp endocarditis. B: A periodic acid–Schiff (PAS) stain highlights numerous yeast forms and occasional septa in this case of Candida sp endocarditis. C: Histoplasma sp can also present as a dimorphic fungus in the cardiovascular system, with both yeast and hyphae identified by silver stain. More about this image found in INFECTIVE ENDOCARDITIS: FUNGAL STAINING A: A silver stain highlights numer...
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<span class="search-highlight">INFECTIVE</span> ENDOCARDITIS: MYCOBACTERIAL  Multiple beaded acid-fast bacilli ar...
Published: 15 November 2023
INFECTIVE ENDOCARDITIS: MYCOBACTERIAL Figure 12-13 INFECTIVE ENDOCARDITIS: MYCOBACTERIAL Multiple beaded acid-fast bacilli are identified. Mycobacterium chimaera can contaminate water and heater systems within cardiopulmonary bypass systems and may be associated with cardiac surgery. More about this image found in INFECTIVE ENDOCARDITIS: MYCOBACTERIAL Multiple beaded acid-fast bacilli ar...
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<span class="search-highlight">INFECTIVE</span> ENDOCARDITIS: HEALED  Left: The injured valve is thickened, and n...
Published: 15 November 2023
INFECTIVE ENDOCARDITIS: HEALED Figure 12-16 INFECTIVE ENDOCARDITIS: HEALED Left: The injured valve is thickened, and numerous thick-walled vessels are in the areas of injury. No vegetation is seen at this stage. Right: An elastic stain highlights the elastic tissue loss and the prominent fibrous... More about this image found in INFECTIVE ENDOCARDITIS: HEALED Left: The injured valve is thickened, and n...
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DEVICE-ASSOCIATED ENDOCARDITIS  Top: An explanted indwelling catheter shows...
Published: 15 November 2023
DEVICE-ASSOCIATED ENDOCARDITIS Figure 12-19 DEVICE-ASSOCIATED ENDOCARDITIS Top: An explanted indwelling catheter shows no visible sign of infection beyond the associated surface thrombus that was received with the device. Bottom: Serial sectioning of this catheter reveals purulent material that ... More about this image found in DEVICE-ASSOCIATED ENDOCARDITIS Top: An explanted indwelling catheter shows...
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CONGENITALLY BICUSPID AORTIC VALVES: REGURGITATION, IN ADULTS  A: Annular d...
Published: 15 November 2023
CONGENITALLY BICUSPID AORTIC VALVES: REGURGITATION, IN ADULTS Figure 36-8 CONGENITALLY BICUSPID AORTIC VALVES: REGURGITATION, IN ADULTS A: Annular dilatation and a short raphe (*) (surgical specimen). B: Prolapse (arrow) of the conjoined cusp due to a stretched raphe (*) (from autopsy). C: Active infective endocarditis (Enterococcus faecalis), involving both cusps (surgical specimen). D: Healed infective endocarditis, with perforation (*) of the nonconjoined cusp (surgical specimen). More about this image found in CONGENITALLY BICUSPID AORTIC VALVES: REGURGITATION, IN ADULTS A: Annular d...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 18
Published: 01 January 2024
10.55418/9781933477367-12
ISBN-10: 1-933477-36-9
ISBN: 978-1-933477-36-7
... , Fairchild   B , Bessonov   AA , Santanelli di Pompeo   F . Finding consensus after two decades of breast implant-associated anaplastic large cell lymphoma . Semin Plast Surg   2019 ; 33 : 270 - 8 . 9. Hu   H , Johani   K , Almatroudi   A , et al . Bacterial biofilm infection...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 18
Published: 01 January 2024
10.55418/9781933477367-14
ISBN-10: 1-933477-36-9
ISBN: 978-1-933477-36-7
... of metastasis. Granulomatous Inflammation/Other Inflammatory Processes Granulomatous inflammation can be seen in axillary lymph nodes ( fig. 14-19 ). When encountered, the differential diagnosis includes systemic conditions, such as sarcoidosis, infection, or an inflammatory reaction, for example...
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SEPTIC SKIN LESIONS  Petechiae or rashes may develop as a consequence of se...
Published: 15 November 2023
SEPTIC SKIN LESIONS Figure 12-1 SEPTIC SKIN LESIONS Petechiae or rashes may develop as a consequence of septic thromboembolism from infection of left-sided cardiac structures, as in a case of Staphylococcus aureus-associated endocarditis of the mitral valve. More about this image found in SEPTIC SKIN LESIONS Petechiae or rashes may develop as a consequence of se...