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hyperplastic
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Images
in Congenital Disorders of the Adrenal Gland
> Tumors of the Adrenal Glands and Extra-Adrenal Paraganglia
Published: 01 December 2024
ADRENAL MYELOLIPOMA IN CONGENITAL ADRENAL HYPERPLASIA Figure 2-17 ADRENAL MYELOLIPOMA IN CONGENITAL ADRENAL HYPERPLASIA A: Huge, bilateral adrenal myelolipomas in an adult male with CAH. The variegated yellow and red coloration results from heterogenous admixture of hematopoietic elements and fat... More about this image found in ADRENAL MYELOLIPOMA IN CONGENITAL ADRENAL HYPERPLASIA A: Huge, bilateral a...
Images
in Clinicopathologic Features of the Adrenal Cortex
> Tumors of the Adrenal Glands and Extra-Adrenal Paraganglia
Published: 01 December 2024
ECTOPIC ACTH SYNDROME DUE TO PHEOCHROMOCYTOMA Figure 3-13 ECTOPIC ACTH SYNDROME DUE TO PHEOCHROMOCYTOMA A 51-year-old white female presented with hypertension, facial swelling, and hirsutism. There were elevated steroid metabolites in the urine which could not be suppressed with high-dose dexamet... More about this image found in ECTOPIC ACTH SYNDROME DUE TO PHEOCHROMOCYTOMA A 51-year-old white female p...
Images
Published: 01 December 2024
DIFFUSE ALDOSTERONE-PRODUCING HYPERPLASIA Figure 4-30 DIFFUSE ALDOSTERONE-PRODUCING HYPERPLASIA A continuous zone of hyperplastic zona glomerulosa is present in non-neoplastic adrenal gland. More about this image found in DIFFUSE ALDOSTERONE-PRODUCING HYPERPLASIA A continuous zone of hyperplasti...
Images
in Hereditary Predisposition to Adrenal Cortical Lesions
> Tumors of the Adrenal Glands and Extra-Adrenal Paraganglia
Published: 01 December 2024
ADRENAL CORTICAL NODULAR DISEASE IN A PATIENT WITH MEN1 ASSOCIATED WITH CUSHING SYNDROME Figure 7-5 ADRENAL CORTICAL NODULAR DISEASE IN A PATIENT WITH MEN1 ASSOCIATED WITH CUSHING SYNDROME A: Marked adrenal enlargement with irregular expansile cortical nodules merging with adjacent hyperplastic c... More about this image found in ADRENAL CORTICAL NODULAR DISEASE IN A PATIENT WITH MEN1 ASSOCIATED WITH CUS...
Images
in Congenital Disorders of the Adrenal Gland
> Tumors of the Adrenal Glands and Extra-Adrenal Paraganglia
Published: 01 December 2024
CONGENITAL ADRENAL HYPERPLASIA Figure 2-12 CONGENITAL ADRENAL HYPERPLASIA A: Marked expansion of the zona fasciculata in an older child with congenital adrenal hyperplasia (CAH). Many cells have lipid-depleted cytoplasm due to sustained trophic stimulation by ACTH. B: Hyperplastic zona fascicula... More about this image found in CONGENITAL ADRENAL HYPERPLASIA A: Marked expansion of the zona fasciculata...
Images
Published: 01 December 2024
PRIMARY PIGMENTED NODULAR ADRENOCORTICAL DISEASE Figure 4-25 PRIMARY PIGMENTED NODULAR ADRENOCORTICAL DISEASE Transverse section through the body of adrenal gland with numerous poorly defined micronodules. Some nodules straddle the corticomedullary junction and impinge on chromaffin cells (white ... More about this image found in PRIMARY PIGMENTED NODULAR ADRENOCORTICAL DISEASE Transverse section throug...
Images
in Congenital Disorders of the Adrenal Gland
> Tumors of the Adrenal Glands and Extra-Adrenal Paraganglia
Published: 01 December 2024
ADRENAL CORTICAL NEOPLASM ASSOCIATED WITH CONGENITAL ADRENAL HYPERPLASIA Figure 2-13 ADRENAL CORTICAL NEOPLASM ASSOCIATED WITH CONGENITAL ADRENAL HYPERPLASIA A: A large adrenal cortical tumor present on the right is seen next to hyperplastic lipid-depleted adrenal cortex and a normal adrenal medu... More about this image found in ADRENAL CORTICAL NEOPLASM ASSOCIATED WITH CONGENITAL ADRENAL HYPERPLASIA A...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-02
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... or incomplete steroid replacement, the histologic features may become altered, with columns and cords of lipid-rich cells admixed with some cells having lipid-depleted cytoplasm. Heterotopic or accessory adrenal cortical tissue can also become enlarged and hyperplastic. CONGENITAL ADRENAL HYPERPLASIA Figure 2...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-04
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
.... However, the nodules tend to be less demarcated from the adjacent cortex, with no clear-cut capsule formation ( figs. 4-5 – 4-7 ). The peri- or internodular cortex is not atrophic or hyperplastic, at variance with macronodular diseases associated with cortisol or aldosterone oversecretion. Cellular...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-03
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... levels normalized. Surgery was complicated by hypotensive episodes. The hyperplastic adrenal cortex was largely lipid depleted. Biopsy of the opposite hyperplastic adrenal gland was identical. Treatment. The treatment of adrenal cortical hyperplasia in patients with ACTH-dependent Cushing syndrome...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-10
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... ). Metastatic disease is rare. There are currently no specific biomarkers for MEN2-associated pheochromocytoma apart from the associated medullary hyperplasia. Hyperplastic nodules or areas contain identical genetic abnormalities as fully developed pheochromocytomas, regardless of their size ( 30 ). ADRENAL...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-07
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... merging with adjacent hyperplastic cortex. B: The nodules consist predom inantly of clear cells as in cortical adenomas. ADRENAL CORTICAL NODULAR DISEASE IN A PATIENT WITH MEN1 ASSOCIATED WITH CUSHING SYNDROME Figure 7-6 ADRENAL CORTICAL NODULAR DISEASE IN A PATIENT WITH MEN1 ASSOCIATED WITH CUSHING...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-08
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... ), and vasoactive intestinal peptide (VIP) giving rise to the watery diarrhea, hypokalemia, and alkalosis syndrome ( 57 ). In the case of local ACTH excess, the surrounding cortex is usually massively hyperplastic and lipid depleted ( fig. 8-40 ). PHEOCHROMOCYTOMA PRODUCING ADRENOCORTICOTROPIC HORMONE (ACTH...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-11
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
..., necrosis, or fibrosis, with collections of foamy macrophages. In addition, areas of lymphocytic infiltrate may be found. An interesting finding is the occurrence of therapy-induced maturation, with areas containing hyperplastic nerves and large conglomerates of ganglion cells, with or without schwannian...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-09
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... paraganglia and paragangliomas in the head and neck is the presence of ectopic, hyperplastic, or neoplastic parathyroid tissue ( figs. 9-8 – 9-10 ). NORMAL CAROTID BODY Figure 9-7 NORMAL CAROTID BODY A: This developing carotid body in an early second trimester stillborn fetus (same case as in figs. 9-3...
Images
Published: 01 September 2024
MOLLUSCUM CONTAGIOSUM Figure 6-12 MOLLUSCUM CONTAGIOSUM Endophytic lobules of hyperplastic epidermis are in the upper dermis (A). There are prominent intracytoplasmic molluscum inclusions (shown at high power in B), with peripheral displacement of the epithelial nucleus. The inclusions typically ... More about this image found in MOLLUSCUM CONTAGIOSUM Endophytic lobules of hyperplastic epidermis are in ...
Images
Published: 01 September 2024
MPOX Figure 6-11 MPOX Microscopic features of skin lesions. (Courtesy of the CDC IDPB) A: Early changes showing a lichenoid papillary dermal and perivascular mixed inflammatory cell infiltrate, which includes lymphocytes, macrophages, and rare eosinophils. Single dyskeratotic cells are visible i... More about this image found in MPOX Microscopic features of skin lesions. (Courtesy of the CDC IDPB) A: ...
Images
Published: 01 September 2024
MPOX Figure 6-11 MPOX Microscopic features of skin lesions. (Courtesy of the CDC IDPB) A: Early changes showing a lichenoid papillary dermal and perivascular mixed inflammatory cell infiltrate, which includes lymphocytes, macrophages, and rare eosinophils. Single dyskeratotic cells are visible i... More about this image found in MPOX Microscopic features of skin lesions. (Courtesy of the CDC IDPB) A: ...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-06
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... with extensive full-thickness epidermal and papillary dermal necrosis, leading to bulla formation. The epidermis at the ulcer margins was hyperplastic, and shows ballooning degeneration of basal keratinocytes and scattered multinucleated keratinocytes. F: Rare eosinophilic epithelial cytoplasmic inclusions...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-08
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... shows a hypercellular appearance, with intranuclear parvovirus B19 inclusions affecting erythroid precursors (A, center and B, bottom). In patients with transient aplastic crisis, the inclusions are found in the hyperplastic bone marrow together with large, abnormal, and sometimes multinucleated...
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