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hyperplasia

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Images
PIGMENTED LENTIGINOUS COMPOUND DYSPLASTIC NEVUS  A: The silhouette of a bro...
Published: 01 February 2024
PIGMENTED LENTIGINOUS COMPOUND DYSPLASTIC NEVUS Figure 4-4 PIGMENTED LENTIGINOUS COMPOUND DYSPLASTIC NEVUS A: The silhouette of a broad plaque-like lesion with epidermal hyperplasia. B: The epidermis shows lentigo-like hyperplasia. Melanin pigment is present in keratinocytes and melanocytes. Sol... More about this image found in PIGMENTED LENTIGINOUS COMPOUND DYSPLASTIC NEVUS A: The silhouette of a bro...
Images
SOLAR LENTIGO AND SEBORRHEIC KERATOSIS  A: Shave biopsy containing both seb...
Published: 01 February 2024
SOLAR LENTIGO AND SEBORRHEIC KERATOSIS Figure 1-2 SOLAR LENTIGO AND SEBORRHEIC KERATOSIS A: Shave biopsy containing both seborrheic keratosis and solar lentigo. B: The solar lentigo component shows slight epidermal hyperplasia associated with hyperpigmentation. More about this image found in SOLAR LENTIGO AND SEBORRHEIC KERATOSIS A: Shave biopsy containing both seb...
Images
SPITZ NEVUS WITH <em>NTRK1</em> REARRANGEMENT  A: Circumscribed com...
Published: 01 February 2024
SPITZ NEVUS WITH NTRK1 REARRANGEMENT Figure 7-28 SPITZ NEVUS WITH NTRK1 REARRANGEMENT A: Circumscribed compound melanocytic proliferation with epidermal hyperplasia. B: The tumor cells homogeneously express NTRK1. C: Fascicles of spindle cells are present at the dermoepidermal junction. The stroma is slightly myxoid. More about this image found in SPITZ NEVUS WITH NTRK1 REARRANGEMENT A: Circumscribed com...
Images
PIGMENTED EPITHELIOID MELANOCYTOMA  A: Silhouette of a heavily pigmented co...
Published: 01 February 2024
PIGMENTED EPITHELIOID MELANOCYTOMA Figure 11-4 PIGMENTED EPITHELIOID MELANOCYTOMA A: Silhouette of a heavily pigmented compound tumor from the back of a 22-year-old male. There is associated epidermal hyperplasia. B: Epithelioid to ovoid cells are present, with a vesicular chromatin pattern and ... More about this image found in PIGMENTED EPITHELIOID MELANOCYTOMA A: Silhouette of a heavily pigmented co...
Images
PIGMENTED EPITHELIOID MELANOCYTOMA  A: Silhouette of a heavily pigmented in...
Published: 01 February 2024
PIGMENTED EPITHELIOID MELANOCYTOMA Figure 11-2 PIGMENTED EPITHELIOID MELANOCYTOMA A: Silhouette of a heavily pigmented intradermal tumor from the shoulder of a 15-year-old boy. B: Junctional melanocytes are present, and many tumor cells involve both the papillary and reticular dermis. There is a... More about this image found in PIGMENTED EPITHELIOID MELANOCYTOMA A: Silhouette of a heavily pigmented in...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-01
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
...  Basal layer hyperpigmentation  Normal density of melanocytes or solar melanocyte hyperplasia  No cytologic atypia  May be inflamed  May be associated with melanophages Differential Diagnosis  Pigmented actinic keratosis  Macular pigmented seborrheic keratosis  Lichenoid...
Images
USUAL DUCTAL <span class="search-highlight">HYPERPLASIA</span>  In this case, usual ductal <span class="search-highlight">hyperplasia</span> (UDH) repr...
Published: 01 January 2024
USUAL DUCTAL HYPERPLASIA Figure 3-6 USUAL DUCTAL HYPERPLASIA In this case, usual ductal hyperplasia (UDH) represented the pathologic correlate for a non-mass-enhancing lesion detected on magnetic resonance imaging (MRI). As is appreciated in this low-power image, the area of involvement by UDH is... More about this image found in USUAL DUCTAL HYPERPLASIA In this case, usual ductal hyperplasia (UDH) repr...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-11
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
... epidermal hyperplasia is common ( fig. 11-2 ). PIGMENTED EPITHELIOID MELANOCYTOMA Figure 11-1 PIGMENTED EPITHELIOID MELANOCYTOMA A: Scanning magnification of a lesion from the back of a 17-year-old girl shows a heavily and uniformly pigmented, symmetrical, circumscribed and predominantly intradermal...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-13
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
... solar melanocyte hyperplasia. LENTIGO MALIGNA MELANOMA IN SITU Figure 13-2 LENTIGO MALIGNA MELANOMA IN SITU A: There is a broad pigmented macular process. The epidermis shows lentigo-like features with hyperpigmentation of keratinocytes and focal slight elongation of rete ridges. Melanophages...
Images
PREGNANCY-LIKE <span class="search-highlight">HYPERPLASIA</span>  Cells with clear, vacuolated cytoplasm fill the...
Published: 01 January 2024
PREGNANCY-LIKE HYPERPLASIA Figure 1-7 PREGNANCY-LIKE HYPERPLASIA Cells with clear, vacuolated cytoplasm fill the lobules (A) and in other areas eosinophilic secretions are present in the acini (B). More about this image found in PREGNANCY-LIKE HYPERPLASIA Cells with clear, vacuolated cytoplasm fill the...
Images
COLUMNAR CELL <span class="search-highlight">HYPERPLASIA</span>  A: At low power, the variably dilated acini that...
Published: 01 January 2024
COLUMNAR CELL HYPERPLASIA Figure 3-2 COLUMNAR CELL HYPERPLASIA A: At low power, the variably dilated acini that characterize columnar cell lesions in general are readily appreciated. The degree of cellular proliferation is slightly greater than that seen in columnar cell change. B: At high power... More about this image found in COLUMNAR CELL HYPERPLASIA A: At low power, the variably dilated acini that...
Images
FLAT EPITHELIAL ATYPIA AND ATYPICAL LOBULAR <span class="search-highlight">HYPERPLASIA</span>  In the center of t...
Published: 01 January 2024
FLAT EPITHELIAL ATYPIA AND ATYPICAL LOBULAR HYPERPLASIA Figure 3-5 FLAT EPITHELIAL ATYPIA AND ATYPICAL LOBULAR HYPERPLASIA In the center of the image is a single acinus lined by cells with low-grade cytologic atypia, i.e., FEA. Surrounding this space are lobules filled with, but not distended by,... More about this image found in FLAT EPITHELIAL ATYPIA AND ATYPICAL LOBULAR HYPERPLASIA In the center of t...
Images
USUAL DUCTAL <span class="search-highlight">HYPERPLASIA</span>  A: At this intermediate-power view, the heterogen...
Published: 01 January 2024
USUAL DUCTAL HYPERPLASIA Figure 3-7 USUAL DUCTAL HYPERPLASIA A: At this intermediate-power view, the heterogeneity of the epithelial cells within the solid proliferation is appreciated. Slit-like spaces at the periphery of the involved duct are seen. B: At higher power, the variability in nuclea... More about this image found in USUAL DUCTAL HYPERPLASIA A: At this intermediate-power view, the heterogen...
Images
USUAL DUCTAL <span class="search-highlight">HYPERPLASIA</span>  This image illustrates the slit-like spaces so ch...
Published: 01 January 2024
USUAL DUCTAL HYPERPLASIA Figure 3-8 USUAL DUCTAL HYPERPLASIA This image illustrates the slit-like spaces so characteristic of UDH. Note the preferential distribution at the periphery of the involved duct. In this example, the myoepithelial cell layer is pronounced because the cytoplasm is clear. More about this image found in USUAL DUCTAL HYPERPLASIA This image illustrates the slit-like spaces so ch...
Images
USUAL DUCTAL <span class="search-highlight">HYPERPLASIA</span>  A: Low-power image shows the variability in size,...
Published: 01 January 2024
USUAL DUCTAL HYPERPLASIA Figure 3-9 USUAL DUCTAL HYPERPLASIA A: Low-power image shows the variability in size, shape, and placement of the epithelial cells in the involved ducts. Epithelial cell polarization is absent around the spaces present. B: High-power view depicts the heterogeneity of nuc... More about this image found in USUAL DUCTAL HYPERPLASIA A: Low-power image shows the variability in size,...
Images
USUAL DUCTAL <span class="search-highlight">HYPERPLASIA</span>  A: UDH with swirling of the epithelial cells in t...
Published: 01 January 2024
USUAL DUCTAL HYPERPLASIA Figure 3-10 USUAL DUCTAL HYPERPLASIA A: UDH with swirling of the epithelial cells in the center of the proliferation. B: High-power image reveals the heterogeneity of the epithelial cells and nuclei, as well as the swirling and streaming of the cells in the center of the... More about this image found in USUAL DUCTAL HYPERPLASIA A: UDH with swirling of the epithelial cells in t...
Images
USUAL DUCTAL <span class="search-highlight">HYPERPLASIA</span>  The epithelial cells in the bridge across a space...
Published: 01 January 2024
USUAL DUCTAL HYPERPLASIA Figure 3-11 USUAL DUCTAL HYPERPLASIA The epithelial cells in the bridge across a space involved by UDH are attenuated. More about this image found in USUAL DUCTAL HYPERPLASIA The epithelial cells in the bridge across a space...
Images
USUAL DUCTAL <span class="search-highlight">HYPERPLASIA</span> WITH NECROSIS  A: Low-power image of an epithelial...
Published: 01 January 2024
USUAL DUCTAL HYPERPLASIA WITH NECROSIS Figure 3-12 USUAL DUCTAL HYPERPLASIA WITH NECROSIS A: Low-power image of an epithelial proliferation with central necrosis. The necrosis may raise concern for ductal carcinoma in situ (DCIS), however, the epithelial cells are not atypical and retain the usua... More about this image found in USUAL DUCTAL HYPERPLASIA WITH NECROSIS A: Low-power image of an epithelial...
Images
USUAL DUCTAL <span class="search-highlight">HYPERPLASIA</span>  A: Low-power view of UDH with a micropapillary or...
Published: 01 January 2024
USUAL DUCTAL HYPERPLASIA Figure 3-13 USUAL DUCTAL HYPERPLASIA A: Low-power view of UDH with a micropapillary or gynecomastoid pattern. B: At higher power, the “pinched tips” of the micropapillations are better appreciated and the variability of the epithelial cells is more apparent. As well, the... More about this image found in USUAL DUCTAL HYPERPLASIA A: Low-power view of UDH with a micropapillary or...
Images
USUAL DUCTAL <span class="search-highlight">HYPERPLASIA</span>  A–C: Hematoxylin and eosin (H&amp;E) (A), CK5/6 i...
Published: 01 January 2024
USUAL DUCTAL HYPERPLASIA Figure 3-14 USUAL DUCTAL HYPERPLASIA A–C: Hematoxylin and eosin (H&E) (A), CK5/6 immunostain (B), and estrogen receptor (ER) (C). In UDH, both CK5/6 and ER display a heterogeneous pattern of expression in the epithelial cells and nuclei respectively: some cells stain ... More about this image found in USUAL DUCTAL HYPERPLASIA A–C: Hematoxylin and eosin (H&E) (A), CK5/6 i...