CONGENITAL ADRENAL HYPERPLASIA Figure 2-10 CONGENITAL ADRENAL HYPERPLASIA This 18-month-old female was mistakenly assigned a male gender. The markedly enlarged clitoris resembles a penis. The hypertrophied clitoris had a urethral opening near the base. The rugosity of the partially fused labio-sc... More about this image found in CONGENITAL ADRENAL HYPERPLASIA This 18-month-old female was mistakenly ass...

CONGENITAL ADRENAL HYPERPLASIA Figure 2-11 CONGENITAL ADRENAL HYPERPLASIA Autopsy of an infant who died of the severe salt-losing form of 21-hydroxylase deficiency shows enlargement of both adrenal glands (arrows). The glands have a convoluted or cerebriform surface and are darker than normal due... More about this image found in CONGENITAL ADRENAL HYPERPLASIA Autopsy of an infant who died of the severe...

CONGENITAL ADRENAL HYPERPLASIA Figure 2-12 CONGENITAL ADRENAL HYPERPLASIA A: Marked expansion of the zona fasciculata in an older child with congenital adrenal hyperplasia (CAH). Many cells have lipid-depleted cytoplasm due to sustained trophic stimulation by ACTH. B: Hyperplastic zona fascicula... More about this image found in CONGENITAL ADRENAL HYPERPLASIA A: Marked expansion of the zona fasciculata...

ADRENAL CORTICAL NEOPLASM ASSOCIATED WITH CONGENITAL ADRENAL HYPERPLASIA Figure 2-13 ADRENAL CORTICAL NEOPLASM ASSOCIATED WITH CONGENITAL ADRENAL HYPERPLASIA A: A large adrenal cortical tumor present on the right is seen next to hyperplastic lipid-depleted adrenal cortex and a normal adrenal medu... More about this image found in ADRENAL CORTICAL NEOPLASM ASSOCIATED WITH CONGENITAL ADRENAL HYPERPLASIA A...

TESTICULAR TUMOR IN CONGENITAL ADRENAL HYPERPLASIA Figure 2-16 TESTICULAR TUMOR IN CONGENITAL ADRENAL HYPERPLASIA Individual cells have distinct cell borders and rounded nuclei, often with one or two eccentric nucleoli. Many cells contain coarse, granular pigment, which is lipofuscin. More about this image found in TESTICULAR TUMOR IN CONGENITAL ADRENAL HYPERPLASIA Individual cells have d...

ADRENAL MYELOLIPOMA IN CONGENITAL ADRENAL HYPERPLASIA Figure 2-17 ADRENAL MYELOLIPOMA IN CONGENITAL ADRENAL HYPERPLASIA A: Huge, bilateral adrenal myelolipomas in an adult male with CAH. The variegated yellow and red coloration results from heterogenous admixture of hematopoietic elements and fat... More about this image found in ADRENAL MYELOLIPOMA IN CONGENITAL ADRENAL HYPERPLASIA A: Huge, bilateral a...

CUSHING DISEASE Figure 3-3 CUSHING DISEASE Bilateral adrenal hyperplasia is seen by computerized tomography (CT) in a patient with an ACTH-dependent, recurrent ACTH-secreting pituitary tumor. (Courtesy of Prof. A. Veltri and Dr. F. Solitro, San Luigi Hospital, Turin, Italy) More about this image found in CUSHING DISEASE Bilateral adrenal hyperplasia is seen by computerized tomo...

CUSHING DISEASE WITH DIFFUSE AND MICRONODULAR HYPERPLASIA Figure 3-5 CUSHING DISEASE WITH DIFFUSE AND MICRONODULAR HYPERPLASIA Transverse sections of adrenal gland in a patient with pituitary ACTH-dependent hypercortisolism (Cushing disease). The adrenal gland was only mildly enlarged and shows b... More about this image found in CUSHING DISEASE WITH DIFFUSE AND MICRONODULAR HYPERPLASIA Transverse secti...

ECTOPIC ACTH SYNDROME Figure 3-9 ECTOPIC ACTH SYNDROME Adrenal cortical hyperplasia shows acidophilic cells expanding the zona fasciculata of the adrenal cortex. More about this image found in ECTOPIC ACTH SYNDROME Adrenal cortical hyperplasia shows acidophilic cells...

ECTOPIC ACTH SYNDROME Figure 3-11 ECTOPIC ACTH SYNDROME Diffuse ACTH-dependent adrenocortical hyperplasia from an adrenal metastasis of an ACTH-secreting lung neuroendocrine tumor. More about this image found in ECTOPIC ACTH SYNDROME Diffuse ACTH-dependent adrenocortical hyperplasia fr...

CUSHING DISEASE Figure 3-12 CUSHING DISEASE Bilateral adrenal hyperplasia in a patient with ACTH-secreting pituitary tumor. There is mild and micronodular increase in size in the left (A) and right (B) adrenal glands. The right gland also has a macronodule (over 1 cm). More about this image found in CUSHING DISEASE Bilateral adrenal hyperplasia in a patient with ACTH-secre...

DIFFUSE ALDOSTERONE-PRODUCING HYPERPLASIA Figure 4-30 DIFFUSE ALDOSTERONE-PRODUCING HYPERPLASIA A continuous zone of hyperplastic zona glomerulosa is present in non-neoplastic adrenal gland. More about this image found in DIFFUSE ALDOSTERONE-PRODUCING HYPERPLASIA A continuous zone of hyperplasti...

NONFUNCTIONAL ADRENAL CORTICAL ADENOMA Figure 5-28 NONFUNCTIONAL ADRENAL CORTICAL ADENOMA Endothelial hyperplasia associated with fibrin (A) and showing mild atypia (B) are present in hemorrhagic areas (same case as fig. 5-27 ). More about this image found in NONFUNCTIONAL ADRENAL CORTICAL ADENOMA Endothelial hyperplasia associated ...

ADRENAL MEDULLARY HYPERPLASIA Figure 8-59 ADRENAL MEDULLARY HYPERPLASIA Adrenal glands from patients with MEN2 (A) and SDHB-related disease (B) show diffuse expansion of the medulla that is much larger than the adrenal cortex on either side. While this is considered to be diffuse hyperplasia, the... More about this image found in ADRENAL MEDULLARY HYPERPLASIA Adrenal glands from patients with MEN2 (A) a...

ADRENAL MEDULLARY HYPERPLASIA IN A PATIENT WITH MEN2A Figure 8-60 ADRENAL MEDULLARY HYPERPLASIA IN A PATIENT WITH MEN2A A: The adrenal medulla is mildly, diffusely thickened and extends into the alae of the gland. A single grossly discernible nodule (arrow) is the clue to the hereditary disease. ... More about this image found in ADRENAL MEDULLARY HYPERPLASIA IN A PATIENT WITH MEN2A A: The adrenal medul...

NODULAR ADRENAL MEDULLARY HYPERPLASIA IN A PATIENT WITH MEN2A Figure 8-61 NODULAR ADRENAL MEDULLARY HYPERPLASIA IN A PATIENT WITH MEN2A A: The adrenal medulla is diffusely thickened and contains multiple nodules. B: At higher magnification there are three nodules that can be distinguished based ... More about this image found in NODULAR ADRENAL MEDULLARY HYPERPLASIA IN A PATIENT WITH MEN2A A: The adren...

ADRENAL MEDULLARY DISEASE IN MULTIPLE ENDOCRINE NEOPLASIA TYPE 2 (MEN2) Figure 10-2 ADRENAL MEDULLARY DISEASE IN MULTIPLE ENDOCRINE NEOPLASIA TYPE 2 (MEN2) A: The adrenal gland has diffuse medullary hyperplasia as well as multiple nodules that represent pheochromocytomas. B,C: The nodules of adr... More about this image found in ADRENAL MEDULLARY DISEASE IN MULTIPLE ENDOCRINE NEOPLASIA TYPE 2 (MEN2) A:...

CUSHING SYNDROME Figure 3-4 CUSHING SYNDROME Magnetic resonance image (MRI) of bilateral adrenal hyperplasia in a patient with ACTH-dependent Cushing syndrome due to ectopic ACTH secretion. More about this image found in CUSHING SYNDROME Magnetic resonance image (MRI) of bilateral adrenal hyper...