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PHEOCHROMOCYTOMA PRODUCING GROWTH HORMONE-RELEASING HORMONE (GHRH) AND CAUS...
Available to Purchase
in Pheochromocytoma and Adrenal Medullary Hyperplasia
> Tumors of the Adrenal Glands and Extra-Adrenal Paraganglia
Published: 01 December 2024
PHEOCHROMOCYTOMA PRODUCING GROWTH HORMONE-RELEASING HORMONE (GHRH) AND CAUSING ACROMEGALY Figure 8-41 PHEOCHROMOCYTOMA PRODUCING GROWTH HORMONE-RELEASING HORMONE (GHRH) AND CAUSING ACROMEGALY The presentation of this patient with acromegaly prompted staining of the tumor for GHRH; the tumor More about this image found in PHEOCHROMOCYTOMA PRODUCING GROWTH HORMONE-RELEASING HORMONE (GHRH) AND CAUS...
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PHEOCHROMOCYTOMA PRODUCING ADRENOCORTICOTROPIC HORMONE (ACTH) AND CAUSING C...
Available to Purchase
in Pheochromocytoma and Adrenal Medullary Hyperplasia
> Tumors of the Adrenal Glands and Extra-Adrenal Paraganglia
Published: 01 December 2024
PHEOCHROMOCYTOMA PRODUCING ADRENOCORTICOTROPIC HORMONE (ACTH) AND CAUSING CUSHING SYNDROME Figure 8-40 PHEOCHROMOCYTOMA PRODUCING ADRENOCORTICOTROPIC HORMONE (ACTH) AND CAUSING CUSHING SYNDROME A: The adrenal cortex is markedly thickened and lipid depleted. B: The tumor is a highly vascular More about this image found in PHEOCHROMOCYTOMA PRODUCING ADRENOCORTICOTROPIC HORMONE (ACTH) AND CAUSING C...
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CONGENITAL ADRENAL HYPERPLASIA Autopsy of an infant who died of the severe...
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in Congenital Disorders of the Adrenal Gland
> Tumors of the Adrenal Glands and Extra-Adrenal Paraganglia
Published: 01 December 2024
due to intense persistent stimulation by adrenocorticotropic hormone (ACTH). More about this image found in CONGENITAL ADRENAL HYPERPLASIA Autopsy of an infant who died of the severe...
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CUSHING SYNDROME The clinical features of this disorder (left) can be caus...
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in Clinicopathologic Features of the Adrenal Cortex
> Tumors of the Adrenal Glands and Extra-Adrenal Paraganglia
Published: 01 December 2024
CUSHING SYNDROME Figure 3-1 CUSHING SYNDROME The clinical features of this disorder (left) can be caused by pituitary adrenocorticotropic hormone (ACTH) excess (top right), ectopic ACTH causing massive adrenal hyperplasia (right middle), or primary adrenal disease (bottom right). (From Netter FH More about this image found in CUSHING SYNDROME The clinical features of this disorder (left) can be caus...
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ADRENAL CORTICAL CARCINOMA IN A YOUNG PATIENT WITH LI-FRAUMENI SYNDROME Ni...
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in Hereditary Predisposition to Adrenal Cortical Lesions
> Tumors of the Adrenal Glands and Extra-Adrenal Paraganglia
Published: 01 December 2024
ADRENAL CORTICAL CARCINOMA IN A YOUNG PATIENT WITH LI-FRAUMENI SYNDROME Figure 7-8 ADRENAL CORTICAL CARCINOMA IN A YOUNG PATIENT WITH LI-FRAUMENI SYNDROME Nine-month-old boy with 8-cm right adrenal tumor. No signs of hormonal overproduction. Resection specimen shows nuclear pleomorphism More about this image found in ADRENAL CORTICAL CARCINOMA IN A YOUNG PATIENT WITH LI-FRAUMENI SYNDROME Ni...
Book Chapter
Clinicopathologic Features of the Adrenal Cortex
Available to PurchaseSeries: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-03
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
...Because the adrenal cortex is the site of synthesis of several hormones, adrenal cortical tumors can be associated with endocrine syndromes that vary depending on the function of the hormone(s) released. The main hormones produced by the adrenal cortex are glucocorticoids, mineralocorticoids...
Book Chapter
Adrenal Cortical Adenoma
Available to PurchaseSeries: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-05
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
...Adrenal cortical adenoma is a benign neoplasm composed of adrenal cortical steroid hormone-producing cells. EPIDEMIOLOGY Adrenal cortical adenomas are not rare, however, the calculation of their real incidence is biased by the use of the term “nodular hyperplasia” for the entity now...
Book Chapter
Pheochromocytoma and Adrenal Medullary Hyperplasia
Available to PurchaseSeries: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-08
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... presentations. Among the incidental lesions, 33.34 percent had a mean delay in diagnosis of 22.95 months (4 to 120 months). Among those with symptoms, patients were younger and more often female, had larger tumors, and had higher preoperative hormone levels. Those with a genetic predisposition were the youngest...
Book Chapter
Adrenal Cortical Carcinoma
Available to PurchaseSeries: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-06
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... prevalence of hormone-secreting tumors and a younger age at diagnosis ( 5 ). The reasons for the increased prevalence of ACC in females is not clearly understood but it has been postulated that the predominance may reflect the sexual dimorphism in the adrenal cortex and the influence of gonadal hormones...
Book Chapter
Physiology, Development, and Anatomy of the Adrenal Glands
Available to PurchaseSeries: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-01
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... classes of steroid hormones: glucocorticoids, mineralocorticoids, and sex hormones ( 4 , 5 ). Their respective biosynthetic pathways are illustrated in figure 1-1 . In the adult cortex, the hormone produced in the largest quantity is cortisol. In contrast, the predominant products of the fetal cortex...
Book Chapter
Congenital Disorders of the Adrenal Gland
Available to PurchaseSeries: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-02
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
...Congenital adrenal gland abnormalities may manifest anatomically, hormonally, or as a combination of the two, and thus present challenges to pathologists and clinicians. A common occurrence is the need to distinguish ectopic cortical tissue from tumor in cancer staging, abdominal surgery...
Book Chapter
Hereditary Predisposition to Adrenal Cortical Lesions
Available to PurchaseSeries: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-07
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... with adrenocorticotropic hormone (ACTH)-independent cortisol secretion represent a heterogeneous group of diseases. They are divided into two subgroups: primary bilateral micronodular adrenal cortical disease and primary bilateral macronodular adrenal cortical disease. They do not constitute two different stages...
Book Chapter
Adrenal Cortical Nodular Diseases
Available to PurchaseSeries: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-04
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... cortical nodular diseases is covered in chapter 7 . Adrenal cortical proliferations, usually without clinical or biochemical evidence of hormone hypersecretion, have been described in the context of Carney triad ( 3 ). This is the combination of gastric gastrointestinal stromal tumor (GIST), pulmonary...
Book Chapter
Other Adrenal Neoplasms and Tumor-Like Lesions
Available to PurchaseSeries: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-12
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
..., with no pheochromocytoma detected. It differs from panic attacks and related conditions in that the episodes are not overtly triggered by fear or anxiety ( 6 ). Pseudo-Cushing is defined by mild to moderate adrenocorticotropic hormone (ACTH)-dependent hypersecretion of cortisol that can be caused by various neural...
Book Chapter
Neuroblastoma, Ganglioneuroblastoma, and Ganglioneuroma
Available to PurchaseSeries: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-11
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... effect (abdominal distension) or pain. Hypertension may develop due to hormonal overproduction or local compression of the renal artery through tumor growth, but appears limited to a minority (4 percent) of patients ( 32 ). In case of (extensive) metastasis, infants and children may show constitutional...
Book Chapter
Paraganglia and Paragangliomas
Available to PurchaseSeries: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-09
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... risk but that high scores have little predictive value in the absence of adjunctive markers ( 116 ). These may include a combination of immunohistochemical markers such as Ki-67 (already included in GAPP), SDHB, and emerging markers such as ATRX ( 116 ), together with hormonal profile, genotype...
Book Chapter
Heart
Available to PurchaseSeries: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-07
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... or gastrointestinal infections that are not associated with myocarditis. Host factors most likely determine an individual’s susceptibility to myocarditis and include pregnancy, sex hormone administration, age, exercise, and nutritional status ( 8 ). The true incidence of myocarditis is difficult to establish due...
Book Chapter
Prion Diseases
Available to PurchaseSeries: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-02
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... human disease can be transmitted via numerous routes, including ingestion, which has been linked to outbreaks of kuru and variant CJD, tissue transplantation, blood transfusion, injection of growth hormone, and use of contaminated surgical instruments. The misfolding and aggregation of prion proteins...
Book Chapter
Respiratory Tract
Available to PurchaseSeries: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-21
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... the hormone inhibits transformation of the fungus from its conidial/mycelial form to its infectious yeast form. The male gender bias among rural workers likely also helps explain the disease predominance in men. The infection mainly affects smokers, heavy drinkers, those with malignancy, and adults between 30...
Book Chapter
Invasive Carcinomas of the Breast
Available to PurchaseSeries: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 18
Published: 01 January 2024
10.55418/9781933477367-08
ISBN-10: 1-933477-36-9
ISBN: 978-1-933477-36-7
... PALB2 DNA repair in association with BRCA1 No specific findings Pancreas Peutz-Jeghers syndrome SKT11 Suppression of cell division Suggestion of grade 2-3 Hormone receptor positive, HER2 negative GI/Pancreas Gyn Testis/Lung Neurofibromatosis type 1 NF1 Negative...
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