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Images
Published: 01 September 2024
DISSEMINATED CLASSIC HISTOPLASMOSIS Figure 23-2 DISSEMINATED CLASSIC HISTOPLASMOSIS There are typical ulcerated mucosal (A) and skin (B) lesions, as well as reticulonodular pulmonary infiltrates seen on chest X-ray (C). (Courtesy of the Centers for Disease Control and Prevention [CDC] Public Heal... More about this image found in DISSEMINATED CLASSIC HISTOPLASMOSIS There are typical ulcerated mucosal (A...
Images
Published: 01 September 2024
HISTOPLASMOSIS CAPSULATUM var. DUBOISII Figure 23-3 HISTOPLASMOSIS CAPSULATUM var. DUBOISII There are multiple focally ulcerating subcutaneous nodules. (Courtesy of the CDC PHIL) More about this image found in HISTOPLASMOSIS CAPSULATUM var. DUBOISII There are multipl...
Images
Published: 01 September 2024
PULMONARY HISTOPLASMOSIS Figure 23-4 PULMONARY HISTOPLASMOSIS Zonal granuloma formation (A) with multiple histiocytes containing a large number of intracytoplasmic Histoplasma spp yeasts (B) are highlighted by a Grocott methenamine stain (GMS) (C). More about this image found in PULMONARY HISTOPLASMOSIS Zonal granuloma formation (A) with multiple histi...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-23
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
...HISTOPLASMOSIS General Considerations, Including Etiology and Synonyms Histoplasma spp are environmental thermally dimorphic fungi that are the cause of histoplasmosis. A pathologist, Samuel T. Darling, first described this disease in 1906 when examining autopsy tissue from...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-01
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... methenamine silver stain on the bone marrow biopsy, which reveals scattered small yeasts demonstrating narrow-neck budding ( fig. 1-2B ). A subsequent urine histoplasmosis antigen test is positive. USE OF SPECIAL STAINS IN THE DIAGNOSIS OF INFECTIOUS DISEASES Figure 1-2 USE OF SPECIAL STAINS...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-21
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... diagnosis of acute/subacute disease includes other infections, such as histoplasmosis, tuberculosis, leishmaniasis, and toxoplasmosis, as well as neoplastic disorders such as lymphoma ( 39 ). In chronic disease, other infections such as tuberculosis, leishmaniasis, and chromoblastomycosis, as well...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-24
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... with disseminated cutaneous disease), the histologic differential diagnosis includes emergomycosis, histoplasmosis, talaromycosis, capsule-deficient cryptococcosis, invasive candidiasis, or even cutaneous pneumocystosis ( 3 ). Table 24-1 SPECTRUM OF INFECTIVE ETIOLOGIC AGENTS ASSOCIATED WITH SKIN LESIONS...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-13
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... complex) infection, and secondary GIT involvement by other systemic infections (such as histoplasmosis and leishmaniasis). Application of appropriate special stains (such as PAS-d, acid-fast, and silver stains) frequently confirm the characteristic intracellular organisms in these other disorders, which...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-12
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... diagnosis includes other infectious diseases, such as fungal (especially histoplasmosis and coccidioidomycosis), bacterial (e.g., Pseudomonas pseudomallei, as well as Nocardia and Actinomyces spp) and other mycobacterial (such as Mycobacterium kansasii) infections ( 93...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 13
Published: 01 November 2022
10.55418/9781933477251-4
ISBN-10: 1-933477-25-3
ISBN: 978-1-933477-25-1
... tumors or craniopharyngiomas, infectious diseases such as tuberculosis or histoplasmosis, infiltrative diseases, lymphocytic hypophysitis, head trauma, and large intracranial artery aneurysms. Postpartum pituitary necrosis secondary to infarction (Sheehan syndrome), pituitary apoplexy, and metastasis...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 12
Published: 01 August 2022
10.55418/9781933477220-11
ISBN-10: 1-933477-22-9
ISBN: 978-1-933477-22-0
..., and rickettsial infections (as well as with nonbacterial infectious agents, including fungi [coccidiomycosis, histoplasmosis, cryptococcosis] and parasites). In tuberculosis, the epididymis is the primary site of genital tract involvement, and the testis is usually affected only in the late stages ( 261 , 262...
Images
Published: 01 January 2022
GRANULOMATOUS HEPATITIS Figure 4-7 GRANULOMATOUS HEPATITIS This case of histoplasmosis showed moderate lobular hepatitis and scattered lobular granulomas. More about this image found in GRANULOMATOUS HEPATITIS This case of histoplasmosis showed moderate lobula...
Images
Published: 01 January 2022
HISTOPLASMOSIS Figure 4-28 HISTOPLASMOSIS Left: The patient presented with fever and weight loss; a biopsy showed a granulomatous hepatitis pattern, with moderate lobular hepatitis and scattered granulomas. Right: The GMS stain is positive. More about this image found in HISTOPLASMOSIS Left: The patient presented with fever and weight loss; a b...
Images
Published: 01 January 2022
POORLY FORMED GRANULOMA Figure 4-8 POORLY FORMED GRANULOMA This poorly formed granuloma is from a case of histoplasmosis. More about this image found in POORLY FORMED GRANULOMA This poorly formed granuloma is from a case of his...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 10
Published: 01 January 2022
10.55418/9781933477183-4
ISBN-10: 1-933477-18-0
ISBN: 978-1-933477-18-3
... GRANULOMATOUS HEPATITIS This case of histoplasmosis showed moderate lobular hepatitis and scattered lobular granulomas. Poorly Formed Granuloma Poorly formed granulomas are histiocyte aggregates that do not meet the criteria for an epithelioid granuloma ( Table 4-4 ), because the individual cells...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 10
Published: 01 January 2022
10.55418/9781933477183-11
ISBN-10: 1-933477-18-0
ISBN: 978-1-933477-18-3
.... Fibrosis and bile ductular reaction should also be reported, but if mild, do not preclude the use of the donor organ ( Table 11-2 ). Active granulomatous disease is generally a contraindication but small fibrotic burned-out appearing lesions likely represent old histoplasmosis infection...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 10
Published: 01 January 2022
10.55418/9781933477183-13
ISBN-10: 1-933477-18-0
ISBN: 978-1-933477-18-3
... X-linked agammaglobulinemia Hepatitis C; other viruses reported include coxsackie, ECHO CD40 ligand deficiency (CD154, hypersyndrome) Biliary Cryptosporidium infections, hepatitis B, hepatitis C, ECHO, histoplasmosis, Bartonella CD40 deficiency Biliary tract and liver...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 10
Published: 01 January 2022
10.55418/9781933477183-1
ISBN-10: 1-933477-18-0
ISBN: 978-1-933477-18-3
... in the setting of fatty liver disease, including Q fever), necrotic granulomas (associated with bacterial or fungal infections), and fibrotic granulomas (associated with sarcoidosis or long-standing histoplasmosis infection). Granulomas are covered in more detail in chapter 4 . Amyloid Amyloid...
Images
in Diseases of the Small Intestine and Colorectum
> Non-Neoplastic Disorders of the Gastrointestinal Tract
Published: 01 April 2021
DUODENAL HISTOPLASMOSIS Figure 4-134 DUODENAL HISTOPLASMOSIS Endoscopic abnormalities include thickened mucosal folds and bulbous villi (A) that reflect distension by sheets of macrophages expanding the lamina propria (B). (A: courtesy of Dr. B. Odum, St. Louis, MO.) Innumerable intracytoplasmic ... More about this image found in DUODENAL HISTOPLASMOSIS Endoscopic abnormalities include thickened mucosal...
Images
Published: 01 April 2021
HISTOPLASMOSIS OF APPENDIX Figure 7-19 HISTOPLASMOSIS OF APPENDIX The lamina propria is expanded by macrophages and multinucleated giant cells that contain numerous round-to-ovoid organisms (A). Fungi are highlighted with methenamine silver counterstained with hematoxylin and eosin (H&E) (B).... More about this image found in HISTOPLASMOSIS OF APPENDIX The lamina propria is expanded by macrophages a...
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