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Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-07
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
...VIRAL MYOCARDITIS General Considerations, Including Etiology and Synonyms Myocarditis, inflammation of the heart muscle frequently associated with myocyte injury and cardiac dysfunction, can have various causes, including viral infection. An integral part of the definitive diagnosis...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-16
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
...INFECTIVE ENDOCARDITIS General Considerations, Including Etiology and Synonyms Endocarditis is defined as inflammation of the endocardial tissue, which may involve the heart valves, chordae tendineae, and septum. The inflammatory process in infective endocarditis is characterized...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-29
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... habits of triatomine insects while travelling in America, also described his own symptoms (which were compatible with acute T. cruzi infection) and died of a “heart condition,” suggesting that he had Chagas disease. Epidemiology Chagas disease is a zoonotic infection that primarily occurs...
Images
Published: 01 September 2024
CHAGAS DISEASE OF THE HEART Figure 29-3 CHAGAS DISEASE OF THE HEART Numerous amastigotes are present in the myocardium. (Courtesy of the CDC PHIL) More about this image found in CHAGAS DISEASE OF THE HEART Numerous amastigotes are present in the myocar...
Images
Published: 01 September 2024
MENINGOCOCCEMIA Figure 11-7 MENINGOCOCCEMIA Meningococcal skin lesion (A) with relatively inapparent bacterial organisms. Gram stain on heart tissue (B), in contrast, shows numerous, more obvious intracellular gram-negative cocci. (Courtesy of the CDC IDPB) More about this image found in MENINGOCOCCEMIA Meningococcal skin lesion (A) with relatively inapparent b...
Images
Published: 01 September 2024
HISTOLOGY OF MENINGOCOCCEMIA Figure 11-9 HISTOLOGY OF MENINGOCOCCEMIA A: Adrenal gland with prominent hemorrhage and focal necrosis. B: Lung showing mild interstitial edema and early intra-alveolar hemorrhage. C: Heart with myocarditis demonstrating striking neutrophil infiltration. (All: court... More about this image found in HISTOLOGY OF MENINGOCOCCEMIA A: Adrenal gland with prominent hemorrhage an...
Images
Published: 01 September 2024
HISTOPLASMA ENDOCARDITIS Figure 23-7 HISTOPLASMA ENDOCARDITIS A: This most often affects the left heart valves, particularly the aortic valve. B,C: There is often underlying valvular disease and organisms usually appear enmeshed in fibrin (B). Short hyphal forms may be seen in these lesions (C) (GMS stain). More about this image found in HISTOPLASMA ENDOCARDITIS A: This most often affects the l...
Images
Published: 01 September 2024
ASPERGILLUS MYOCARDITIS Figure 7-5 ASPERGILLUS MYOCARDITIS Gross appearance of a horizontal heart slice, showing areas of hemorrhage and infarction (A). Hematoxylin and eosin (H&E) histology shows angioinvasive growth (B) with numerous partly degenerated fungal hyphae and surrounding neutrophils (C). Grocott methenamine silver stain highlights focally branching fungal hyphae (D). More about this image found in ASPERGILLUS MYOCARDITIS Gross appearance of a horizontal ...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-04
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
..., although this has not been determined in the same manner in different countries. Risk factors for severe COVID-19 disease include type 2 diabetes mellitus, obesity, serious heart disease, chronic lung or kidney disease, malignancy, organ transplants, and sickle cell disease. Due to the large number...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-25
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
..., especially the heart (due to the large number of parasitic cysts present in muscle tissue) but also the kidney and liver. Hemopoietic stem cell transplants and, rarely, blood transfusions are other possible routes of transmission. Figure 25-1 illustrates the life cycle of T. gondii, with felids...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-11
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... in individuals with prosthetic valves or prior rheumatic heart disease Mortality 25-30% Cutaneous Abattoir workers Low-grade fever and papulopustular skin lesions Eye involvement can also occur Gastroenteritis During outbreaks Diarrhea, fever, fatigue, chills, and myalgia, usually 24 hours...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-23
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... and constitutional and respiratory symptoms. Skin and oral lesions, hepatosplenomegaly, and involvement of bone marrow, adrenal gland, heart, gastrointestinal tract, and eye can be seen ( fig. 23-2 ). Central nervous system (CNS) disease can occur in acute, subacute, and chronic disseminated infection and presents...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-27
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... to shock. Chronic malaria can be associated with hepatofibrosis but does not lead to cirrhosis. A characteristic finding in multiple organs (including the liver, spleen, lung, heart, and brain) is the presence of hemozoin pigment, which may be extremely abundant and impart a dark brown, slate gray, or even...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-17
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... is affected, the disease is called Parinaud oculoglandular syndrome Although rare, heart and neurologic complications can occur B. henselae Systemic Mimics manifestations of autoimmune disease, such as juvenile arthritis, myositis, leukocytoclastic vasculitis, and Henoch-Schoenlein purpura...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-22
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... microabscess formation. Deep Organ Involvement/Systemic Infections. These include candidemia, chronic systemic candidiasis, and infection of various organ sites such as the central nervous system (CNS), eye, bone and joints, respiratory and urinary tracts, heart, peritoneum, and intra-abdominal organs...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-14
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... surfaces (pleural effusion and spontaneous bacterial peritonitis), gastrointestinal and hepatopancreatobiliary tracts (enterocolitis, intestinal obstruction, granulomatous hepatitis, liver abscesses, and acute and chronic pancreatitis), and heart (endocarditis, myocarditis, and pericarditis), among others...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-10
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
..., areas of cellular degeneration, either as contiguous, nonzonal foci of necrosis or single cell apoptosis, are typically seen in the liver ( fig. 10-8 ), but can also occur in the spleen, adrenal gland, and heart ( 17 ). The random distribution of the liver necrosis contrasts with yellow fever, which...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-13
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
.... Complications include bowel perforation and rectal bleeding. In septicemic patients, infection of viscera such as the liver, spleen, and heart; intra-abdominal abscess formation; and mesenteric thrombosis may occur. In up to 10 percent of patients, reactive arthritis and erythema nodosum have been described...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-12
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... cocci and bacterial antigens in numerous tissues including the lung, meninges, heart, adrenal gland, spleen, liver, and kidney. Laboratory Diagnosis Culture remains the reference standard for the diagnosis of pneumococcal infection but, ideally, sterile body fluids (blood, sputum, other respiratory...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-09
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... b Gut Leishmania spp Skin, lymphoid tissue, gut, liver, bone marrow + + Microsporidia Gut, liver, eye Scabies Skin Strongyloides stercoralis Gut, systemic Toxoplasma gondii b Brain, heart, lung + + Trypanosoma cruzi...
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