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Book Chapter
Adrenal Cortical Carcinoma
Available to PurchaseSeries: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-06
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... of the lack of aromatase. However, some studies show high aromatase cytochrome P450 (CYP19A1) mRNA and aromatase activity in ACCs producing estrogens ( 60 ). Estrogen production in male patients is associated with gynecomastia, whereas adult female patients are relatively asymptomatic ( 60 – 62 ). Aldosterone...
Images
GYNECOMASTIA: LATER STAGE In this case of gynecomastia, there is much more...
Available to PurchasePublished: 01 January 2024
GYNECOMASTIA: LATER STAGE Figure 10-4 GYNECOMASTIA: LATER STAGE In this case of gynecomastia, there is much more stromal fibrosis. More about this image found in GYNECOMASTIA: LATER STAGE In this case of gynecomastia, there is much more...
Images
GYNECOMASTIA A: There is a greater degree of epithelial hyperplasia presen...
Available to PurchasePublished: 01 January 2024
GYNECOMASTIA Figure 10-2 GYNECOMASTIA A: There is a greater degree of epithelial hyperplasia present within the ducts than is typical of male breast tissue. B: At intermediate power, the heterogeneity of the epithelial cells is more readily appreciated. Some micropapillations are present, which More about this image found in GYNECOMASTIA A: There is a greater degree of epithelial hyperplasia presen...
Book Chapter
Male Breast Lesions
Available to PurchaseSeries: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 18
Published: 01 January 2024
10.55418/9781933477367-10
ISBN-10: 1-933477-36-9
ISBN: 978-1-933477-36-7
...Table 10-1 FEATURES OF GYNECOMASTIA Clinical Features Bimodal age at presentation: puberty and older age Most cases are idiopathic, though known risk factors include: Hypogonadism and low testosterone states Hyperestrogen states Marijuana and anabolic steroids...
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PSEUDOANGIOMATOUS STROMAL HYPERPLASIA IN A CASE OF GYNECOMASTIA
Available to PurchasePublished: 01 January 2024
PSEUDOANGIOMATOUS STROMAL HYPERPLASIA IN A CASE OF GYNECOMASTIA Figure 10-5 PSEUDOANGIOMATOUS STROMAL HYPERPLASIA IN A CASE OF GYNECOMASTIA More about this image found in PSEUDOANGIOMATOUS STROMAL HYPERPLASIA IN A CASE OF GYNECOMASTIA
Images
GYNECOMASTIA A: At low power, breast ducts, some with epithelial hyperplas...
Available to PurchasePublished: 01 January 2024
GYNECOMASTIA Figure 10-1 GYNECOMASTIA A: At low power, breast ducts, some with epithelial hyperplasia, are embedded in a loose, edematous stroma. B: Micropapillary usual ductal hyperplasia (UDH) is present in this duct. A few chronic inflammatory cells are present in the stroma. More about this image found in GYNECOMASTIA A: At low power, breast ducts, some with epithelial hyperplas...
Images
ATYPICAL DUCTAL HYPERPLASIA (ADH) IN GYNECOMASTIA A: This duct is involved...
Available to PurchasePublished: 01 January 2024
ATYPICAL DUCTAL HYPERPLASIA (ADH) IN GYNECOMASTIA Figure 10-3 ATYPICAL DUCTAL HYPERPLASIA (ADH) IN GYNECOMASTIA A: This duct is involved by a monotonous proliferation of atypical epithelial cells. B: At higher power, areas of epithelial cell polarization are apparent. The degree of cytologic More about this image found in ATYPICAL DUCTAL HYPERPLASIA (ADH) IN GYNECOMASTIA A: This duct is involved...
Book Chapter
Breast Lesions in Children and Adolescents
Available to PurchaseSeries: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 18
Published: 01 January 2024
10.55418/9781933477367-09
ISBN-10: 1-933477-36-9
ISBN: 978-1-933477-36-7
... , Aliapoulios MA . Gynecomastia in marihuana users . N Engl J Med 1972 ; 287 : 936 . 6. Karagüzel G , Bilen S , Karaçal N , Yildiz K , Livaoglu M . Virginal breast hypertrophy: different presentations of 2 cases and the role of tamoxifen as an adjuvant therapy . J...
Book Chapter
Mesenchymal Lesions
Available to PurchaseSeries: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 18
Published: 01 January 2024
10.55418/9781933477367-11
ISBN-10: 1-933477-36-9
ISBN: 978-1-933477-36-7
... as a palpable mass. Most women with PASH are premenopausal, and men with PASH often have concomitant gynecomastia ( 34 ). These observations suggest a hormonal association; it is thought that an aberrant myofibroblastic response to progesterone may be a factor involved in the development of PASH. Gross Findings...
Book Chapter
Tumors and Tumor-Like Lesions of the Vulva
Available to PurchaseSeries: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 14
Published: 01 February 2023
10.55418/9781933477268-5
ISBN-10: 1-933477-26-1
ISBN: 978-1-933477-26-8
... of stage. Anogenital mammary-like glands may also give rise to other lesions identical to those that occur in the breast. These include gynecomastia-like hyperplasia, fibroadenoma, pseudoangiomatous stromal hyperplasia, and phyllodes tumor ( 116 – 118 ). A variety of benign sweat gland neoplasms have been...
Images
GYNECOMASTIA IN A PATIENTWITH CHORIOCARCINOMA
Available to Purchase
in Germ Cell Neoplasia in Situ and Tumors Derived from Germ Cell Neoplasia in Situ
> Tumors and Tumor-Like Lesions of the Testis and Adjacent Tissues
Published: 01 August 2022
GYNECOMASTIA IN A PATIENTWITH CHORIOCARCINOMA Figure 4-136 GYNECOMASTIA IN A PATIENTWITH CHORIOCARCINOMA More about this image found in GYNECOMASTIA IN A PATIENTWITH CHORIOCARCINOMA
Images
A PATIENT WITH A LEYDIG CELL TUMOR Note the gynecomastia.
Available to PurchasePublished: 01 August 2022
A PATIENT WITH A LEYDIG CELL TUMOR Figure 6-1 A PATIENT WITH A LEYDIG CELL TUMOR Note the gynecomastia. More about this image found in A PATIENT WITH A LEYDIG CELL TUMOR Note the gynecomastia.
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A PATIENT WITH AN ADULT-TYPE GRANULOSA CELL TUMOR There is prominent scrot...
Available to PurchasePublished: 01 August 2022
A PATIENT WITH AN ADULT-TYPE GRANULOSA CELL TUMOR Figure 6-119 A PATIENT WITH AN ADULT-TYPE GRANULOSA CELL TUMOR There is prominent scrotal enlargement and gynecomastia. (figs. 6-119 and 6-120 are from the same patient.) More about this image found in A PATIENT WITH AN ADULT-TYPE GRANULOSA CELL TUMOR There is prominent scrot...
Images
RUPTURED CORPUS LUTEUM IN AN OVOTESTIS A hemorrhagic corpus luteum is pres...
Available to PurchasePublished: 01 August 2022
and gynecomastia. Examination of the gonad led to the diagnosis. (Courtesy of Dr. F. Vellios, Atlanta, GA and Dr. J. Albores-Saavedra, Dallas, TX) More about this image found in RUPTURED CORPUS LUTEUM IN AN OVOTESTIS A hemorrhagic corpus luteum is pres...
Book Chapter
Pituitary Gland
Available to PurchaseSeries: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 13
Published: 01 November 2022
10.55418/9781933477251-1
ISBN-10: 1-933477-25-3
ISBN: 978-1-933477-25-1
..., gynecomastia and testicular atrophy ( 290 ). In contrast, panhypopituitarism and single hormone deficiencies besides hypogonadotropic hypogonadism are rare. Dysfunction of lactotroph ( 286 , 291 ) or somatotroph ( 285 , 287 , 291 , 292 ) cell secretory capacity has been demonstrated in a few studies...
Book Chapter
Sex Cord-Stromal Tumors
Available to PurchaseSeries: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 12
Published: 01 August 2022
10.55418/9781933477220-06
ISBN-10: 1-933477-22-9
ISBN: 978-1-933477-22-0
..., significant nuclear atypia, tumor necrosis, lymphovascular invasion a Data from references 153 and 177a . Table 6-6 GENERALIZATIONS CONCERNING THE TESTICULAR LESIONS IN THE PEUTZ-JEGHERS SYNDROME VERSUS THOSE IN THE CARNEY COMPLEX Peutz-Jeghers Carney Presentation gynecomastia mass...
Book Chapter
Testicular Tumors: General Considerations
Available to PurchaseSeries: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 12
Published: 01 August 2022
10.55418/9781933477220-01
ISBN-10: 1-933477-22-9
ISBN: 978-1-933477-22-0
... and consequent increased circulating androgen. This situation is attributable to the luteinizing hormone (LH)-like activity of hCG secondary to the occurrence of identical alpha subunits within both hormones. Increased testosterone is typically manifested in adult patients as gynecomastia because of its...
Book Chapter
Mixed Germ Cell-Sex Cord-Stromal Tumors
Available to PurchaseSeries: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 12
Published: 01 August 2022
10.55418/9781933477220-07
ISBN-10: 1-933477-22-9
ISBN: 978-1-933477-22-0
..., and gynecomastia ( 1 – 3 ). Most cases are found in infancy during investigation for a possible disorder of sex development (DSD) because of ambiguous external genitalia ( 2 , 3 ). Some present later, typically with findings related to an invasive germ cell tumor or, in phenotypic females (the majority...
Book Chapter
Germ Cell Neoplasia in Situ and Tumors Derived from Germ Cell Neoplasia in Situ
Available to PurchaseSeries: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 12
Published: 01 August 2022
10.55418/9781933477220-04
ISBN-10: 1-933477-22-9
ISBN: 978-1-933477-22-0
... to bubbly cytoplasm and nuclei with coarse chromatin and prominent nucleoli (Diff-Quik stain). GYNECOMASTIA IN A PATIENTWITH CHORIOCARCINOMA Figure 4-136 GYNECOMASTIA IN A PATIENTWITH CHORIOCARCINOMA CHORIOCARCINOMA Figure 4-139 CHORIOCARCINOMA Left: A large zone of hemorrhage is bordered by a rim...
Book Chapter
Normal Testicular Development, Structure, and Function
Available to PurchaseSeries: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 12
Published: 01 August 2022
10.55418/9781933477220-02
ISBN-10: 1-933477-22-9
ISBN: 978-1-933477-22-0
... Leydig cells to proliferate and secrete testosterone, which is converted to estrogen in adipose tissue through the action of aromatase, resulting in gynecomastia in some cases. Similarly, its TSH-like activity may result in thyroid gland hyperplasia and thyrotoxicosis. OCT3/4 (POU5F1) is encoded...
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