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Images
Published: 01 December 2024
PHEOCHROMOCYTOMA PRODUCING GROWTH HORMONE-RELEASING HORMONE (GHRH) AND CAUSING ACROMEGALY Figure 8-41 PHEOCHROMOCYTOMA PRODUCING GROWTH HORMONE-RELEASING HORMONE (GHRH) AND CAUSING ACROMEGALY The presentation of this patient with acromegaly prompted staining of the tumor for GHRH; the tumor is di... More about this image found in PHEOCHROMOCYTOMA PRODUCING GROWTH HORMONE-RELEASING HORMONE (GHRH) AND CAUS...
Images
Published: 01 December 2024
VAGAL PARAGANGLIOMA WITH INTRANEURAL GROWTH Figure 9-17 VAGAL PARAGANGLIOMA WITH INTRANEURAL GROWTH Intraneural extension of the tumor at center is accompanied by extensive infiltration of the surrounding tissue. More about this image found in VAGAL PARAGANGLIOMA WITH INTRANEURAL GROWTH Intraneural extension of the t...
Images
Published: 01 December 2024
URINARY BLADDER PARAGANGLIOMA Figure 9-18 URINARY BLADDER PARAGANGLIOMA This paraganglioma shows extensive superficial growth beneath the mucosa. The tumor is a potential mimic of urothelial carcinoma because of its growth pattern and pale eosinophilic to clear cytoplasm. More about this image found in URINARY BLADDER PARAGANGLIOMA This paraganglioma shows extensive superfici...
Images
Published: 01 December 2024
ADENOCARCINOMA OF BREAST METASTATIC TO ADRENAL GLAND Figure 12-24 ADENOCARCINOMA OF BREAST METASTATIC TO ADRENAL GLAND A: The pattern of growth shows a well-developed glandular arrangement of tumor cells. B: Metastatic poorly differentiated adenocarcinoma has a sinusoidal pattern, with growth as... More about this image found in ADENOCARCINOMA OF BREAST METASTATIC TO ADRENAL GLAND A: The pattern of gro...
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Images
Published: 01 December 2024
ADRENAL CORTICAL ADENOMA, ONCOCYTIC TYPE Figure 5-39 ADRENAL CORTICAL ADENOMA, ONCOCYTIC TYPE Deeply eosinophilic large cells in a diffuse pattern of growth with prominent nucleoli. More about this image found in ADRENAL CORTICAL ADENOMA, ONCOCYTIC TYPE Deeply eosinophilic large cells i...
Images
Published: 01 December 2024
VAGAL PARAGANGLIOMA Figure 9-16 VAGAL PARAGANGLIOMA A: The prominent blood vessels and a pericyte-like arrangement of tumor cells may suggest a vascular tumor in the differential diagnosis. B: A different area of the same tumor shows a solid growth pattern with prominent perivascular pseudoroset... More about this image found in VAGAL PARAGANGLIOMA A: The prominent blood vessels and a pericyte-like arr...
Images
Published: 01 December 2024
URINARY BLADDER PARAGANGLIOMA Figure 9-22 URINARY BLADDER PARAGANGLIOMA A: This paraganglioma extends between muscle bundles in the bladder wall and is a potential mimic of other more aggressive neoplasms because of its growth pattern. B: Higher magnification of the tumor shows that most neoplas... More about this image found in URINARY BLADDER PARAGANGLIOMA A: This paraganglioma extends between muscle...
Images
Published: 01 December 2024
ADRENAL CORTICAL CARCINOMA IN A YOUNG PATIENT WITH LI-FRAUMENI SYNDROME Figure 7-8 ADRENAL CORTICAL CARCINOMA IN A YOUNG PATIENT WITH LI-FRAUMENI SYNDROME Nine-month-old boy with 8-cm right adrenal tumor. No signs of hormonal overproduction. Resection specimen shows nuclear pleomorphism and incre... More about this image found in ADRENAL CORTICAL CARCINOMA IN A YOUNG PATIENT WITH LI-FRAUMENI SYNDROME Ni...
Images
Published: 01 December 2024
JUVENILE (CAPILLARY) ADRENAL HEMANGIOMA Figure 12-9 JUVENILE (CAPILLARY) ADRENAL HEMANGIOMA A,B: Small juvenile hemangioma of the adrenal gland in a newborn. There were numerous cutaneous hemangiomas and a large vascular tumor of the liver with identical histology. The adrenal tumor is uniformly ... More about this image found in JUVENILE (CAPILLARY) ADRENAL HEMANGIOMA A,B: Small juvenile hemangioma of ...
Images
Published: 01 December 2024
PRIMARY ADRENAL ANGIOSARCOMA Figure 12-10 PRIMARY ADRENAL ANGIOSARCOMA A: There is well-developed vasoformative architecture with sinusoidal growth between cords of vacuolated cortical cells. Acute inflammatory cells and eosinophils are also present. B: Primary adrenal angiosarcoma (same case as... More about this image found in PRIMARY ADRENAL ANGIOSARCOMA A: There is well-developed vasoformative arch...
Images
Published: 01 December 2024
MESENTERIC PARAGANGLIOMA Figure 9-14 MESENTERIC PARAGANGLIOMA A: This paraganglioma composed of basophilic and clear cells was incidentally discovered in an asymptomatic patient with no other tumors. Fat invasion, poorly defined irregular cell nests, and diffuse growth are putative risk factors f... More about this image found in MESENTERIC PARAGANGLIOMA A: This paraganglioma composed of basophilic and ...
Images
Published: 01 December 2024
CAROTID BODY PARAGANGLIOMA Figure 9-15 CAROTID BODY PARAGANGLIOMA A: Tumor tissue in most parts of the tumor (same specimen as fig. 9-12 ) shows uniform round nests of weakly eosinophilic cells and cavernous blood vessels. B: This section, taken at the interface between the circumscribed fleshy... More about this image found in CAROTID BODY PARAGANGLIOMA A: Tumor tissue in most parts of the tumor (sam...
Images
Published: 01 December 2024
CAROTID BODY PARAGANGLIOMA Figure 9-15 CAROTID BODY PARAGANGLIOMA A: Tumor tissue in most parts of the tumor (same specimen as fig. 9-12 ) shows uniform round nests of weakly eosinophilic cells and cavernous blood vessels. B: This section, taken at the interface between the circumscribed fleshy... More about this image found in CAROTID BODY PARAGANGLIOMA A: Tumor tissue in most parts of the tumor (sam...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-09
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... genotype and potentially aggressive behavior associated with mutations of the SDHB gene ( 61 , 64 ). An overall mean growth rate for paragangliomas has minimal meaning because tumor characteristics are dependent on tumor genotype. However, even for the most aggressive tumors, the growth rate...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-08
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... Spindle cell morphology is also seen in tumors with solid cohesive growth. PHEOCHROMOCYTOMA Figure 8-25 PHEOCHROMOCYTOMA The tumor cell nuclei usually have prominent and occasionally multiple nucleoli, and some have clear pseudo-inclusions. PHEOCHROMOCYTOMA Figure 8-26 PHEOCHROMOCYTOMA Some tumors...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-06
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... years has also been suggested as a risk factor for ACC in females ( 9 ), supported by the in vitro evidence of antiproliferative effects of estrogen and progesterone inhibition on ACC cells ( 11 , 12 ); the known occurrence and rapid growth of ACC in pregnancy, however, contradicts these in vitro...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-02
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... is sometimes associated with midline congenital defects such as spinal dysraphism and indeterminate visceral situs, and occasionally, the Cornelia de Lange syndrome (mental and growth retardation, synophrys, anteverted nostrils, low-set ears, and spade-like hands with short tapering fingers) ( 1 ). It is also...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-01
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... and function in endocrine neoplasia. Endocrine Pathol 2023;34:382-92.) Glucocorticoids regulate the intermediary metabolism of carbohydrates, fat, and proteins, and affect processes including wound healing, growth, inflammation, and functions of the immune system. In addition to these systemic effects...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-11
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... effect (abdominal distension) or pain. Hypertension may develop due to hormonal overproduction or local compression of the renal artery through tumor growth, but appears limited to a minority (4 percent) of patients ( 32 ). In case of (extensive) metastasis, infants and children may show constitutional...