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Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 16
Published: 01 August 2023
10.55418/9781933477282-04
ISBN-10: 1-933477-28-8
ISBN: 978-1-933477-28-2
...  with microinvasive low-grade serous carcinoma (LGSC) Low-grade serous carcinoma High-grade serous carcinoma a WHO Classification of Tumours Editorial Board. Female genital tumours, 5th ed. Lyon: IARC; 2020. Table 4-2 KEY DIAGNOSTIC FEATURES OF SEROUS BORDERLINE TUMOR, MICROINVASION, AND IMPLANTS...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 16
Published: 01 August 2023
10.55418/9781933477282-05
ISBN-10: 1-933477-28-8
ISBN: 978-1-933477-28-2
...Table 5-1 ASSIGNMENT OF PRIMARY SITE FOR EXTRAUTERINE HIGH-GRADE SEROUS CARCINOMA Primary Site Fallopian Tube Ovary Peritoneal STIC a present OR Both fallopian tubes separate from ovarian mass Both tubes and both ovaries fully examined Criteria for diagnosis...
Images
LOW-<span class="search-highlight">GRADE</span> SEROUS TUMOR  Left, right: This low-<span class="search-highlight">grade</span> serous tumor represents...
Published: 01 August 2023
LOW-GRADE SEROUS TUMOR Figure 4-15 LOW-GRADE SEROUS TUMOR Left, right: This low-grade serous tumor represents extensive fusion of the epithelium, similar to the surface cribriform growth pattern depicted in fig. 4-11 . This type of proliferation is difficult to classify, but in the absence of st... More about this image found in LOW-GRADE SEROUS TUMOR Left, right: This low-grade serous tumor represents...
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CYTOLOGIC FEATURES OF HIGH-<span class="search-highlight">GRADE</span> SEROUS CARCINOMA  There are high-<span class="search-highlight">grade</span> nuc...
Published: 01 August 2023
CYTOLOGIC FEATURES OF HIGH-GRADE SEROUS CARCINOMA Figure 5-8 CYTOLOGIC FEATURES OF HIGH-GRADE SEROUS CARCINOMA There are high-grade nuclear features with numerous mitotic figures (right, arrow) and occasional very large pleomorphic cells (left, arrow). More about this image found in CYTOLOGIC FEATURES OF HIGH-GRADE SEROUS CARCINOMA There are high-grade nuc...
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HIGH-<span class="search-highlight">GRADE</span> SEROUS CARCINOMA WITH CYTOPLASMIC CLEARING  High-<span class="search-highlight">grade</span> serous ca...
Published: 01 August 2023
HIGH-GRADE SEROUS CARCINOMA WITH CYTOPLASMIC CLEARING Figure 6-15 HIGH-GRADE SEROUS CARCINOMA WITH CYTOPLASMIC CLEARING High-grade serous carcinoma (A,B) may resemble oxyphilic clear cell carcinoma after treatment (C). More about this image found in HIGH-GRADE SEROUS CARCINOMA WITH CYTOPLASMIC CLEARING High-grade serous ca...
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HIGH-<span class="search-highlight">GRADE</span> ENDOMETRIOID ADENOCARCINOMA  Four examples of high-<span class="search-highlight">grade</span> endomet...
Published: 01 August 2023
HIGH-GRADE ENDOMETRIOID ADENOCARCINOMA Figure 7-21 HIGH-GRADE ENDOMETRIOID ADENOCARCINOMA Four examples of high-grade endometrioid carcinoma (A–D). Confirmatory endometrioid features were present in each case, an example of which is shown in B. More about this image found in HIGH-GRADE ENDOMETRIOID ADENOCARCINOMA Four examples of high-grade endomet...
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LOW-<span class="search-highlight">GRADE</span> APPENDICEAL MUCINOUS NEOPLASM INVOLVING FALLOPIAN TUBE (DISSEMINA...
Published: 01 August 2023
LOW-GRADE APPENDICEAL MUCINOUS NEOPLASM INVOLVING FALLOPIAN TUBE (DISSEMINATED PERITONEAL ADENOMUCINOSIS/WELL-DIFFERENTIATED MUCINOUS ADENOCARCINOMA OF APPENDIX) Figure 16-37 LOW-GRADE APPENDICEAL MUCINOUS NEOPLASM INVOLVING FALLOPIAN TUBE (DISSEMINATED PERITONEAL ADENOMUCINOSIS/WELL-DIFFERENTIATE... More about this image found in LOW-GRADE APPENDICEAL MUCINOUS NEOPLASM INVOLVING FALLOPIAN TUBE (DISSEMINA...
Images
INVASIVE IMPLANT/LOW-<span class="search-highlight">GRADE</span> SEROUS CARCINOMA  A–C: The presence of invasion ...
Published: 01 August 2023
INVASIVE IMPLANT/LOW-GRADE SEROUS CARCINOMA Figure 4-20 INVASIVE IMPLANT/LOW-GRADE SEROUS CARCINOMA A–C: The presence of invasion is now synonymous with low-grade serous carcinoma. In the case of an invasive implant, the invasion is identified in the peritoneal or omental tumor, and is not found ... More about this image found in INVASIVE IMPLANT/LOW-GRADE SEROUS CARCINOMA A–C: The presence of invasion ...
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LOW-<span class="search-highlight">GRADE</span> SEROUS CARCINOMA  There is an abundance of epithelium compared to...
Published: 01 August 2023
LOW-GRADE SEROUS CARCINOMA Figure 4-25 LOW-GRADE SEROUS CARCINOMA There is an abundance of epithelium compared to stroma. In addition, there are no papillae with hierarchical branching, but rather abundant invasive epithelial structures in a stroma with retraction. More about this image found in LOW-GRADE SEROUS CARCINOMA There is an abundance of epithelium compared to...
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SEROUS PSAMMOCARCINOMA  This low-<span class="search-highlight">grade</span> serous carcinoma has abundant psammo...
Published: 01 August 2023
SEROUS PSAMMOCARCINOMA Figure 4-27 SEROUS PSAMMOCARCINOMA This low-grade serous carcinoma has abundant psammomatous calcifications. By definition, more than 75 percent of the tumor nests must contain calcifications to diagnose serous psammocarcinoma. More about this image found in SEROUS PSAMMOCARCINOMA This low-grade serous carcinoma has abundant psammo...
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HIGH-<span class="search-highlight">GRADE</span> SEROUS CARCINOMA SALPINGO-OOPHORECTOMY SPECIMEN  The fimbrial en...
Published: 01 August 2023
HIGH-GRADE SEROUS CARCINOMA SALPINGO-OOPHORECTOMY SPECIMEN Figure 5-2 HIGH-GRADE SEROUS CARCINOMA SALPINGO-OOPHORECTOMY SPECIMEN The fimbrial end of the fallopian tube disappears into this mass, consistent with a primary tubal high-grade serous carcinoma. More about this image found in HIGH-GRADE SEROUS CARCINOMA SALPINGO-OOPHORECTOMY SPECIMEN The fimbrial en...
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PAPILLARY ARCHITECTURE IN HIGH-<span class="search-highlight">GRADE</span> SEROUS CARCINOMA  Papillary architectu...
Published: 01 August 2023
PAPILLARY ARCHITECTURE IN HIGH-GRADE SEROUS CARCINOMA Figure 5-4 PAPILLARY ARCHITECTURE IN HIGH-GRADE SEROUS CARCINOMA Papillary architecture is most characteristic of high-grade serous carcinoma and is present in most tumors, at least focally. More fused papillae with irregular spaces (A,B) or m... More about this image found in PAPILLARY ARCHITECTURE IN HIGH-GRADE SEROUS CARCINOMA Papillary architectu...
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SOLID ARCHITECTURE  Solid architecture is common in high-<span class="search-highlight">grade</span> serous carci...
Published: 01 August 2023
SOLID ARCHITECTURE Figure 5-5 SOLID ARCHITECTURE Solid architecture is common in high-grade serous carcinoma and should not lead to a diagnosis of a mixed carcinoma with an undifferentiated component. More about this image found in SOLID ARCHITECTURE Solid architecture is common in high-grade serous carci...
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MUCINOUS DIFFERENTIATION IN HIGH-<span class="search-highlight">GRADE</span> SEROUS CARCINOMA  This unusual high-...
Published: 01 August 2023
MUCINOUS DIFFERENTIATION IN HIGH-GRADE SEROUS CARCINOMA Figure 5-9 MUCINOUS DIFFERENTIATION IN HIGH-GRADE SEROUS CARCINOMA This unusual high-grade serous carcinoma shows prominent intracellular mucin (left) and signet ring cells (right). More about this image found in MUCINOUS DIFFERENTIATION IN HIGH-GRADE SEROUS CARCINOMA This unusual high-...
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TROPHOBLASTIC DIFFERENTIATION IN HIGH-<span class="search-highlight">GRADE</span> SEROUS CARCINOMA  Transdifferen...
Published: 01 August 2023
TROPHOBLASTIC DIFFERENTIATION IN HIGH-GRADE SEROUS CARCINOMA Figure 5-10 TROPHOBLASTIC DIFFERENTIATION IN HIGH-GRADE SEROUS CARCINOMA Transdifferentiation, with formation of syncytiotrophoblast and cytotrophoblast, in an otherwise typical high-grade serous carcinoma. More about this image found in TROPHOBLASTIC DIFFERENTIATION IN HIGH-GRADE SEROUS CARCINOMA Transdifferen...
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ENDOMETRIOID-LIKE GROWTH OF HIGH-<span class="search-highlight">GRADE</span> SEROUS CARCINOMA  This architectural...
Published: 01 August 2023
ENDOMETRIOID-LIKE GROWTH OF HIGH-GRADE SEROUS CARCINOMA Figure 5-14 ENDOMETRIOID-LIKE GROWTH OF HIGH-GRADE SEROUS CARCINOMA This architectural pattern of high-grade serous carcinoma can be confused with endometrioid carcinoma with squamous differentiation (A), but the presence of strong diffuse W... More about this image found in ENDOMETRIOID-LIKE GROWTH OF HIGH-GRADE SEROUS CARCINOMA This architectural...
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SEROUS BORDERLINE TUMOR WITH PROGRESSION TO HIGH-<span class="search-highlight">GRADE</span> CARCINOMA  This sero...
Published: 01 August 2023
SEROUS BORDERLINE TUMOR WITH PROGRESSION TO HIGH-GRADE CARCINOMA Figure 5-16 SEROUS BORDERLINE TUMOR WITH PROGRESSION TO HIGH-GRADE CARCINOMA This serous borderline tumor (A), has progressed to higher grade carcinoma with both papillary (B) and solid (C) architecture. More about this image found in SEROUS BORDERLINE TUMOR WITH PROGRESSION TO HIGH-GRADE CARCINOMA This sero...
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PSEUDOENDOMETRIOID HIGH-<span class="search-highlight">GRADE</span> SEROUS CARCINOMA  A: This example might be mi...
Published: 01 August 2023
PSEUDOENDOMETRIOID HIGH-GRADE SEROUS CARCINOMA Figure 7-23 PSEUDOENDOMETRIOID HIGH-GRADE SEROUS CARCINOMA A: This example might be misinterpreted as endometrioid adenocarcinoma because of the cribriform architecture. B: Glands are lined by highly atypical cells. C: Cytologic detail. More about this image found in PSEUDOENDOMETRIOID HIGH-GRADE SEROUS CARCINOMA A: This example might be mi...