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gonadoblastoma
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Images
in Mixed Germ Cell-Sex Cord-Stromal Tumors
> Tumors and Tumor-Like Lesions of the Testis and Adjacent Tissues
Published: 01 August 2022
GONADOBLASTOMA Figure 7-2 GONADOBLASTOMA Nests of gonadoblastoma are present at left, above the rete testis (bottom left), with immature seminiferous tubules on the right. More
Images
in Mixed Germ Cell-Sex Cord-Stromal Tumors
> Tumors and Tumor-Like Lesions of the Testis and Adjacent Tissues
Published: 01 August 2022
GONADOBLASTOMA Figure 7-4 GONADOBLASTOMA In this nest of gonadoblastoma, many of the germ cells resemble those of seminoma, although a few are smaller and similar to spermatogonia. Sex cord cells are at the periphery of the nest and partially surround some of the germ cells and spherical deposits... More
Images
in Mixed Germ Cell-Sex Cord-Stromal Tumors
> Tumors and Tumor-Like Lesions of the Testis and Adjacent Tissues
Published: 01 August 2022
GONADOBLASTOMA Figure 7-1 GONADOBLASTOMA Bilateral gonadoblastomas with pink-tan cut surfaces contain white, “gritty” calcifications throughout; the gonad on the right also shows a solid white area of germinoma. Bilateral fallopian tubes are present. (Fig. 8 from Ulbright TM, Young RH. Gonadoblas... More
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 12
Published: 01 August 2022
DOI:
10.55418/9781933477220-07
ISBN-10: 1-933477-22-9
ISBN: 978-1-933477-22-0
...GONADOBLASTOMA Figure 7-2 GONADOBLASTOMA Nests of gonadoblastoma are present at left, above the rete testis (bottom left), with immature seminiferous tubules on the right. GONADOBLASTOMA Figure 7-3 GONADOBLASTOMA Discrete nests are composed of dark sex cord cells that surround germ cells...
Images
in Mixed Germ Cell-Sex Cord-Stromal Tumors
> Tumors and Tumor-Like Lesions of the Testis and Adjacent Tissues
Published: 01 August 2022
GONADOBLASTOMA AND UNDIFFERENTIATED GONADAL TISSUE Figure 7-7 GONADOBLASTOMA AND UNDIFFERENTIATED GONADAL TISSUE A: Confluent nests of gonadoblastoma (diffuse or expansile pattern), resembling germinoma on low power, are associated with classic nests of gonadoblastoma (top and bottom right). B: ... More
Images
in Mixed Germ Cell-Sex Cord-Stromal Tumors
> Tumors and Tumor-Like Lesions of the Testis and Adjacent Tissues
Published: 01 August 2022
GONADOBLASTOMA Figure 7-3 GONADOBLASTOMA Discrete nests are composed of dark sex cord cells that surround germ cells with clear cytoplasm and round deposits of basement membrane material. A single laminated calcification is present. More
Images
in Mixed Germ Cell-Sex Cord-Stromal Tumors
> Tumors and Tumor-Like Lesions of the Testis and Adjacent Tissues
Published: 01 August 2022
GONADOBLASTOMA Figure 7-5 GONADOBLASTOMA There are both follicular and Call-Exner-like patterns. In the former, sex cord cells with grooved nuclei surround individual germ cells, and in the latter, sex cord cells are arranged around spherical deposits of basement membrane. The appearance of the g... More
Images
in Mixed Germ Cell-Sex Cord-Stromal Tumors
> Tumors and Tumor-Like Lesions of the Testis and Adjacent Tissues
Published: 01 August 2022
BURNT-OUT GONADOBLASTOMA Figure 7-6 BURNT-OUT GONADOBLASTOMA Islands of irregular and mulberry-shaped calcifications devoid of neoplastic cells are in a background of cellular stroma. More
Images
in Mixed Germ Cell-Sex Cord-Stromal Tumors
> Tumors and Tumor-Like Lesions of the Testis and Adjacent Tissues
Published: 01 August 2022
GONADOBLASTOMA Figure 7-8 GONADOBLASTOMA Left: In this dissecting pattern (or undifferentiated gonadal tissue) small nests and cords of germ cells and sex cord cells closely resemble the infiltrative growth pattern of germinoma. Right: Cords of germ cells with sex cord cells surround two discret... More
Images
in Mixed Germ Cell-Sex Cord-Stromal Tumors
> Tumors and Tumor-Like Lesions of the Testis and Adjacent Tissues
Published: 01 August 2022
GONADOBLASTOMA Figure 7-10 GONADOBLASTOMA Left: The nests are confluent and the germ cells prominent, closely resembling seminoma on low power. Right: Close inspection shows a consistent sex cord cell component as well as the polymorphic nature of the germ cells. More
Images
in Mixed Germ Cell-Sex Cord-Stromal Tumors
> Tumors and Tumor-Like Lesions of the Testis and Adjacent Tissues
Published: 01 August 2022
SERTOLI CELL NODULE WITH GCNIS AND SEMINOMA Figure 7-9 SERTOLI CELL NODULE WITH GCNIS AND SEMINOMA GCNIS involves a Sertoli cell nodule, potentially simulating gonadoblastoma. The focal distribution of the GCNIS cells in the Sertoli cell nodule contrasts to their diffuse distribution in gonadobla... More
Images
Published: 01 August 2022
SERTOLI CELL NODULE WITH GERM CELL NEOPLASIA IN SITU (GCNIS) Figure 11-12 SERTOLI CELL NODULE WITH GERM CELL NEOPLASIA IN SITU (GCNIS) A portion of this Sertoli cell nodule has been colonized by GCNIS cells, thereby resembling gonadoblastoma. Uninvolved tubules are at the left. More
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 12
Published: 01 August 2022
DOI:
10.55418/9781933477220-03
ISBN-10: 1-933477-22-9
ISBN: 978-1-933477-22-0
... tumors Myoid gonadal stromal tumor Other rare sex cord-stromal tumors Mixed Germ Cell and Sex Cord-Stromal Tumor Gonadoblastoma Unclassified mixed germ cell-sex cord-stromal tumor Miscellaneous Tumors of the Testis and Adnexal Structures Ovarian epithelial-type tumors...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 12
Published: 01 August 2022
DOI:
10.55418/9781933477220-11
ISBN-10: 1-933477-22-9
ISBN: 978-1-933477-22-0
..., thereby resembling gonadoblastoma. Uninvolved tubules are at the left. SERTOLI CELL NODULE Figure 11-10 SERTOLI CELL NODULE Left: The cellular elements in this case have been entirely replaced by basement membrane matrix. Right: A macroscopic lesion has a multinodular/lobulated configuration. NORMAL...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 12
Published: 01 August 2022
DOI:
10.55418/9781933477220-05
ISBN-10: 1-933477-22-9
ISBN: 978-1-933477-22-0
... tumor composed of a spermatocytic tumor-like component and germinoma arising in gonadoblastoma in a phenotypic woman with a 46, XX peripheral karyotype: report of the first case . Am J Surg Pathol 2017 ; 41 : 1290 - 7 . 127. Jacobsen GK , Barlebo H , Olsen J , et al...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 12
Published: 01 August 2022
DOI:
10.55418/9781933477220-04
ISBN-10: 1-933477-22-9
ISBN: 978-1-933477-22-0
... an endometrioid carcinoma . Hum Pathol 1987 ; 18 : 1296 - 9 . 525. Scully RE . Gonadoblastoma. A review of 74 cases . Cancer 1970 ; 25 : 1340 - 56 . 526. Chhieng DC , Jennings TA , Slominski A , Mihm MC Jr . Choriocarcinoma presenting as a cutaneous metastasis...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 12
Published: 01 August 2022
DOI:
10.55418/9781933477220-06
ISBN-10: 1-933477-22-9
ISBN: 978-1-933477-22-0
... tubules in a case of the androgen insensitivity syndrome . Cancer 1985 ; 55 : 1607 - 11 . 254. Ulbright TM , Young RH . Gonadoblastoma and selected other aspects of gonadal pathology in young patients with disorders of sex development . Semin Diagn Pathol 2014 ; 31 : 427 - 40...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 12
Published: 01 August 2022
DOI:
10.55418/9781933477220-08
ISBN-10: 1-933477-22-9
ISBN: 978-1-933477-22-0
... , Steele SM Jr . Coexisting rete testis adenoma and gonadoblastoma . J Urol 1982 ; 127 : 332 - 5 . 207. Jones MA , Young RH . Sertoliform rete cystadenoma: a report of two cases . J Urol Pathol 1997 ; 7 : 47 - 53 . 208. Sinclair AM , Gunendran T , Napier...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 1
Published: 01 January 2020
DOI:
10.55418/9781933477916-03
ISBN-10: 1-933477-91-1
ISBN: 978-1-933477-91-6
... of anterior pituitary, uterine, and placental expression . Endocr Rev 1991 ; 12 : 402 - 23 . 285. Hoffman WH , Galan RR , Kovacs K , Subramanian MG . Ectopic prolactin secretion from a gonadoblastoma . Cancer 1987 ; 60 : 2690 - 5 . 286. Klibanski A . Osteoporosis...
