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Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-01
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
...   Mucocutaneous myxomas   Blue nevi  2. Multiple endocrine neoplasia type   Pigmented nodular adrenocortical disease   Pituitary adenoma   Gonadal tumors   Thyroid tumors   Schwannomas (may include malignant melanotic nerve sheath tumors) Leopard Syndrome: aut dom, PTPN11...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 18
Published: 01 January 2024
10.55418/9781933477367-09
ISBN-10: 1-933477-36-9
ISBN: 978-1-933477-36-7
... affect postpubertal girls. The condition is extremely debilitating, causing back and neck pain, as well as being socially distressing. Circulating gonadal hormonal levels are normal and definitive risk factors have not been identified, although studies have hypothesized end-organ hypersensitivity...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch49
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
.... Intracardiac teratomas, because of their septal location, are more difficult to remove than pericardial teratomas. However, even incomplete excision has been shown to be beneficial ( 38 ). Similar to the behavior of germ cell tumors in the gonads, pure teratomas are benign in the pediatric population...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch10
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... carcinoid secretory products, left-sided cardiac involvement is rare. Gonadal carcinoids have direct access to the systemic venous return and are not subject to the portal circulation; their bioactive products can therefore act on the right heart before metastasizing. Certain drugs, such as the anorexigens...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch21
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... hepatic metastasis or directly (e.g., gonadal carcinoids). 5-hydroxyindoleacetic acid (5-HIAA) is the primary serotonin metabolite thought to be responsible for stimulating proliferation of endocardial and valvular interstitial cells. This causes dense white plaques to form on the endocardial surfaces...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch30
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... evaluation is required to determine whether the vasculitis is isolated or likely isolated. Ascending aortitis, for instance, is frequently confined to the aorta (see above). Likewise, vasculitis is identified in the gonads, uterus, and gallbladder, and is often isolated ( 81 , 82 ). Polyarteritis-Like Single...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch01
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
... , 120 ). Visceral branches arise anteriorly and supply the digestive system and spleen. Parietal branches originate laterally (including renal, adrenal, and gonadal arteries), and posteriorly (as lumbar arteries). The median sacral artery arises at the aortic bifurcation. Ductal Artery and Ligament...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 16
Published: 01 August 2023
10.55418/9781933477282-13
ISBN-10: 1-933477-28-8
ISBN: 978-1-933477-28-2
... . Tumors of the ovary, maldeveloped gonads, fallopian tube and broad ligament . AFIP Atlas of Tumor Pathology , 3rd Series, Fascicle 23 . Washington DC : American Registry of Pathology ; 1998 . 7a. Logothetis   CJ , Samuels   ML , Trindade   A , Johnson   DE . The growing teratoma...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 16
Published: 01 August 2023
10.55418/9781933477282-01
ISBN-10: 1-933477-28-8
ISBN: 978-1-933477-28-2
...   J , Jaffe   RB . Development and regulation of growth and differentiated function in human and subhuman primate fetal gonads . Endocr Rev   1990 ; 11 : 532 - 57 . 5. Reeves   G . Specific stroma in the cortex and medulla of the ovary. Cell types and vascular supply in relation...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 16
Published: 01 August 2023
10.55418/9781933477282-12
ISBN-10: 1-933477-28-8
ISBN: 978-1-933477-28-2
...   Z . Studies of gonadal sex differentiation . Organogenesis   2016 ; 12 : 42 - 51 . 2. Shah   SP , Kobel   M , Senz   J , et al   Mutation of FOXL2 in granulosa-cell tumors of the ovary . N Engl J Med   2009 ; 360 : 2719 - 29 . 3. Wang   Y , Chen   J , Yang   W...
Images
YOLK SAC TUMOR  A,B: Like its <span class="search-highlight">gonadal</span> and vaginal counterparts, yolk sac tu...
Published: 01 February 2023
YOLK SAC TUMOR Figure 5-93 YOLK SAC TUMOR A,B: Like its gonadal and vaginal counterparts, yolk sac tumor in the vulva features distinctive glandular and cystic architecture (A) consisting of cuboidal to columnar cells forming irregular glands and papillary structures (B); Schiller-Duval bodies ca... More about this image found in YOLK SAC TUMOR A,B: Like its gonadal and vaginal counterparts, yolk sac tu...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 15
Published: 01 March 2023
10.55418/9781933477275-05
ISBN-10: 1-933477-27-X
ISBN: 978-1-933477-27-5
... gonad comes in close proximity to the dorsal pancreatic anlage (which gives rise to the body and tail of the pancreas) during the fourth and fifth weeks of development ( 3 , 69 ). This raises the possibility that cells from the primitive ovary can be incorporated into the embryonic pancreas...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 14
Published: 01 February 2023
10.55418/9781933477268-1
ISBN-10: 1-933477-26-1
ISBN: 978-1-933477-26-8
... of interference by androgenic hormone and despite inactivated estrogen receptor proteins or aromatases. SRY, the sex-determining gene located on the short arm of the Y chromosome, is critical in gonadal sex differentiation: the absence of SRY confers or “permits” female gonadal differentiation...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 14
Published: 01 February 2023
10.55418/9781933477268-4
ISBN-10: 1-933477-26-1
ISBN: 978-1-933477-26-8
... presenting symptom. Like gonadal yolk sac tumors, serum alpha-fetoprotein (AFP) is elevated and may be a useful marker of treatment success and recurrence ( 210 ). Gross Findings. Tumors may be exophytic/ polypoid or sessile; mucosal ulceration is common ( 211 ). The cut surface is hemorrhagic and often...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 14
Published: 01 February 2023
10.55418/9781933477268-5
ISBN-10: 1-933477-26-1
ISBN: 978-1-933477-26-8
.... Immunohistochemistry is usually required to confirm the myeloid lineage of these cells. YOLK SAC TUMOR Figure 5-93 YOLK SAC TUMOR A,B: Like its gonadal and vaginal counterparts, yolk sac tumor in the vulva features distinctive glandular and cystic architecture (A) consisting of cuboidal to columnar cells forming...
Images
GONADOBLASTOMA  Left: In this dissecting pattern (or undifferentiated <span class="search-highlight">gonad</span>...
Published: 01 August 2022
GONADOBLASTOMA Figure 7-8 GONADOBLASTOMA Left: In this dissecting pattern (or undifferentiated gonadal tissue) small nests and cords of germ cells and sex cord cells closely resemble the infiltrative growth pattern of germinoma. Right: Cords of germ cells with sex cord cells surround two discret... More about this image found in GONADOBLASTOMA Left: In this dissecting pattern (or undifferentiated gonad...
Images
EMBRYOLOGY OF TESTIS  The <span class="search-highlight">gonad</span> is first recognized at 4 to 5 weeks of gest...
Published: 01 August 2022
EMBRYOLOGY OF TESTIS Figure 2-1 EMBRYOLOGY OF TESTIS The gonad is first recognized at 4 to 5 weeks of gestation as a thickening of the intermediate mesoderm of the ventromedial aspect of the mesonephros, forming the genital, or gonadal, ridge. At 6 weeks, and simultaneously with the arrival of th... More about this image found in EMBRYOLOGY OF TESTIS The gonad is first recognized at 4 to 5 weeks of gest...
Images
EMBRYOLOGY OF TESTIS  Early in development, the configuration of the <span class="search-highlight">gonad</span> ...
Published: 01 August 2022
EMBRYOLOGY OF TESTIS Figure 2-2 EMBRYOLOGY OF TESTIS Early in development, the configuration of the gonad (in red) is elongated between the root of the dorsal mesentery and the mesonephros. (Fig. 16-17 from Sadler TW. Langman’s medical embryology, 12th ed. Philadelphia: Wolters Kluwer; 2011:243.)... More about this image found in EMBRYOLOGY OF TESTIS Early in development, the configuration of the gonad ...
Images
FIBROTHECOMA  An intratesticular <span class="search-highlight">gonadal</span> fibrothecoma is well circumscribed...
Published: 01 August 2022
FIBROTHECOMA Figure 6-143 FIBROTHECOMA An intratesticular gonadal fibrothecoma is well circumscribed, with a homogeneous gray-white cut surface. (Fig. 1A from Zhang M, Kao CS, Ulbright TM, Epstein JI. Testicular fibrothecoma: a morphologic and immunohistochemical study of 16 cases. Am J Surg Path... More about this image found in FIBROTHECOMA An intratesticular gonadal fibrothecoma is well circumscribed...
Images
MYOID <span class="search-highlight">GONADAL</span> STROMAL TUMOR  A circumscribed, nonencapsulated tumor with pr...
Published: 01 August 2022
MYOID GONADAL STROMAL TUMOR Figure 6-166 MYOID GONADAL STROMAL TUMOR A circumscribed, nonencapsulated tumor with prominent blood vessels is seen in the testis. More about this image found in MYOID GONADAL STROMAL TUMOR A circumscribed, nonencapsulated tumor with pr...