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Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-02
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
...Congenital adrenal gland abnormalities may manifest anatomically, hormonally, or as a combination of the two, and thus present challenges to pathologists and clinicians. A common occurrence is the need to distinguish ectopic cortical tissue from tumor in cancer staging, abdominal surgery...
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FUSION OF ADRENAL <span class="search-highlight">GLANDS</span>  Newborn infant at autopsy with adrenal <span class="search-highlight">glands</span> (ar...
Published: 01 December 2024
FUSION OF ADRENAL GLANDS Figure 2-3 FUSION OF ADRENAL GLANDS Newborn infant at autopsy with adrenal glands (arrows) fused in the midline anterior to the aorta. More about this image found in FUSION OF ADRENAL GLANDS Newborn infant at autopsy with adrenal glands (ar...
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MAJOR BIOSYNTHETIC PATHWAYS FOR STEROIDOGENESIS  Both adrenal <span class="search-highlight">gland</span> and gon...
Published: 01 December 2024
MAJOR BIOSYNTHETIC PATHWAYS FOR STEROIDOGENESIS Figure 1-1 MAJOR BIOSYNTHETIC PATHWAYS FOR STEROIDOGENESIS Both adrenal gland and gonadal pathways are shown. Functions distinguishing the adrenal cortical zones from each other and from the gonads are determined by differential expression of steroi... More about this image found in MAJOR BIOSYNTHETIC PATHWAYS FOR STEROIDOGENESIS Both adrenal gland and gon...
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PRIMORDIA OF ADRENAL <span class="search-highlight">GLAND</span>  Schematic cross section of human embryo shows p...
Published: 01 December 2024
PRIMORDIA OF ADRENAL GLAND Figure 1-3 PRIMORDIA OF ADRENAL GLAND Schematic cross section of human embryo shows primordia of adrenal glands, which are located lateral to the base of the dorsal mesentery, separated from the gonadal primordium by the adrenal groove. (Fig. 1-3 from Lack EE, Kozakewic... More about this image found in PRIMORDIA OF ADRENAL GLAND Schematic cross section of human embryo shows p...
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FETAL ADRENAL <span class="search-highlight">GLAND</span> AND KIDNEY  Coronal sections (left and right) of adrena...
Published: 01 December 2024
FETAL ADRENAL GLAND AND KIDNEY Figure 1-4 FETAL ADRENAL GLAND AND KIDNEY Coronal sections (left and right) of adrenal gland and kidney from a fetus of about 18 weeks’ gestational age. External aspect of one specimen is at bottom. Medullary tissue is not evident macroscopically at this early stage... More about this image found in FETAL ADRENAL GLAND AND KIDNEY Coronal sections (left and right) of adrena...
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FETAL ADRENAL <span class="search-highlight">GLAND</span> AND KIDNEY  Coronal section of adrenal kidney and adjac...
Published: 01 December 2024
FETAL ADRENAL GLAND AND KIDNEY Figure 1-5 FETAL ADRENAL GLAND AND KIDNEY Coronal section of adrenal kidney and adjacent tissue from a fetus at approximately 11 weeks’ gestational age. The developing para-aortic sympathetic plexus has a close relationship with the medial and inferior aspects of th... More about this image found in FETAL ADRENAL GLAND AND KIDNEY Coronal section of adrenal kidney and adjac...
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LATE GESTATION ADRENAL <span class="search-highlight">GLAND</span> FROM A PREMATURE STILLBORN  Most of this adren...
Published: 01 December 2024
LATE GESTATION ADRENAL GLAND FROM A PREMATURE STILLBORN Figure 1-7 LATE GESTATION ADRENAL GLAND FROM A PREMATURE STILLBORN Most of this adrenal gland is composed of provisional cortical cells with abundant eosinophilic cytoplasm. There is a vague suggestion of columns resembling zona fasciculata,... More about this image found in LATE GESTATION ADRENAL GLAND FROM A PREMATURE STILLBORN Most of this adren...
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MEDIAL ASPECT OF DEVELOPING ADRENAL <span class="search-highlight">GLAND</span> IN HUMAN FETUS  Coronal section o...
Published: 01 December 2024
MEDIAL ASPECT OF DEVELOPING ADRENAL GLAND IN HUMAN FETUS Figure 1-9 MEDIAL ASPECT OF DEVELOPING ADRENAL GLAND IN HUMAN FETUS Coronal section of fetal adrenal gland shows close association with developing sympathetic plexus (on far left). Small nests of primitive sympathetic cells (white arrows) a... More about this image found in MEDIAL ASPECT OF DEVELOPING ADRENAL GLAND IN HUMAN FETUS Coronal section o...
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TYROSINE HYDROXYLASE IN DEVELOPING FETAL ADRENAL <span class="search-highlight">GLAND</span>  Most of the medulla...
Published: 01 December 2024
TYROSINE HYDROXYLASE IN DEVELOPING FETAL ADRENAL GLAND Figure 1-13 TYROSINE HYDROXYLASE IN DEVELOPING FETAL ADRENAL GLAND Most of the medullary progenitor cells in this image express TH. Because TH is a cytosolic enzyme, it can often detect ability to produce catecholamines in immature or poorly ... More about this image found in TYROSINE HYDROXYLASE IN DEVELOPING FETAL ADRENAL GLAND Most of the medulla...
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S-100 PROTEIN IN DEVELOPING FETAL ADRENAL <span class="search-highlight">GLAND</span>  Some S-100 protein-positiv...
Published: 01 December 2024
S-100 PROTEIN IN DEVELOPING FETAL ADRENAL GLAND Figure 1-14 S-100 PROTEIN IN DEVELOPING FETAL ADRENAL GLAND Some S-100 protein-positive cells are present at the periphery of a small neuroblastic aggregate (right), while others are associated with scattered more mature-appearing cells with clear c... More about this image found in S-100 PROTEIN IN DEVELOPING FETAL ADRENAL GLAND Some S-100 protein-positiv...
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Ki-67 IN FETAL ADRENAL <span class="search-highlight">GLAND</span>  Immunoreactivity for Ki-67 is abundant in the...
Published: 01 December 2024
Ki-67 IN FETAL ADRENAL GLAND Figure 1-15 Ki-67 IN FETAL ADRENAL GLAND Immunoreactivity for Ki-67 is abundant in the definitive zone, which is the major site of cortical cell generation. Scattered individual stained cortical cells are also present in the provisional zone, along with aggregates of ... More about this image found in Ki-67 IN FETAL ADRENAL GLAND Immunoreactivity for Ki-67 is abundant in the...
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ADRENAL <span class="search-highlight">GLAND</span> FROM A 35-WEEK PREMATURE INFANT  In this transverse section, ...
Published: 01 December 2024
ADRENAL GLAND FROM A 35-WEEK PREMATURE INFANT Figure 1-18 ADRENAL GLAND FROM A 35-WEEK PREMATURE INFANT In this transverse section, much of the fetal or provisional cortex has a dark appearance. This may be a normal feature and should not be confused with adrenal hemorrhage. More about this image found in ADRENAL GLAND FROM A 35-WEEK PREMATURE INFANT In this transverse section, ...
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DORSAL AND VENTRAL SURFACES OF ADULT ADRENAL <span class="search-highlight">GLAND</span>  A: In the adult, the do...
Published: 01 December 2024
DORSAL AND VENTRAL SURFACES OF ADULT ADRENAL GLAND Figure 1-19 DORSAL AND VENTRAL SURFACES OF ADULT ADRENAL GLAND A: In the adult, the dorsal surface of the right adrenal gland is pyramidal, while the opposite gland is more elongated. A few cortical extrusions are present. B: Central adrenal vei... More about this image found in DORSAL AND VENTRAL SURFACES OF ADULT ADRENAL GLAND A: In the adult, the do...
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TOPOGRAPHY OF THE ADULT ADRENAL <span class="search-highlight">GLAND</span>  A: Serial transverse sections show t...
Published: 01 December 2024
TOPOGRAPHY OF THE ADULT ADRENAL GLAND Figure 1-22 TOPOGRAPHY OF THE ADULT ADRENAL GLAND A: Serial transverse sections show three regions of the gland: the head (medial and inferior in situ), body, and tail (superior and lateral in situ). Most of the chromaffin tissue is concentrated in the body a... More about this image found in TOPOGRAPHY OF THE ADULT ADRENAL GLAND A: Serial transverse sections show t...
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BODY AND HEAD OF NORMAL ADRENAL <span class="search-highlight">GLAND</span>  In this transverse section, the medu...
Published: 01 December 2024
BODY AND HEAD OF NORMAL ADRENAL GLAND Figure 1-23 BODY AND HEAD OF NORMAL ADRENAL GLAND In this transverse section, the medullary compartment appears dull gray in contrast to the bright yellow cortex. Partial to complete cuffs of cortex are present around the central adrenal vein and its tributar... More about this image found in BODY AND HEAD OF NORMAL ADRENAL GLAND In this transverse section, the medu...
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BODY AND HEAD OF A NODULAR ADRENAL <span class="search-highlight">GLAND</span>  In this architecturally distorted...
Published: 01 December 2024
BODY AND HEAD OF A NODULAR ADRENAL GLAND Figure 1-24 BODY AND HEAD OF A NODULAR ADRENAL GLAND In this architecturally distorted gland in transverse section, the adrenal cortex is bright yellow, with focal nodularity. Medullary tissue is prominent and extends into both wings (alae) of the gland. T... More about this image found in BODY AND HEAD OF A NODULAR ADRENAL GLAND In this architecturally distorted...
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PERINATAL ADRENAL <span class="search-highlight">GLAND</span> SHOWING DEFINITIVE AND PROVISIONAL ZONES BEFORE INV...
Published: 01 December 2024
PERINATAL ADRENAL GLAND SHOWING DEFINITIVE AND PROVISIONAL ZONES BEFORE INVOLUTION Figure 1-25 PERINATAL ADRENAL GLAND SHOWING DEFINITIVE AND PROVISIONAL ZONES BEFORE INVOLUTION Definitive cortex forms a thin rim of subcapsular cells, which have a high nuclear to cytoplasmic ratio. Most of the co... More about this image found in PERINATAL ADRENAL GLAND SHOWING DEFINITIVE AND PROVISIONAL ZONES BEFORE INV...
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EXTRUSION OF CORTICAL TISSUE THROUGH THE CAPSULE OF NORMAL ADRENAL <span class="search-highlight">GLAND</span>  A...
Published: 01 December 2024
EXTRUSION OF CORTICAL TISSUE THROUGH THE CAPSULE OF NORMAL ADRENAL GLAND Figure 1-28 EXTRUSION OF CORTICAL TISSUE THROUGH THE CAPSULE OF NORMAL ADRENAL GLAND A: Extracapsular perivascular extrusion of cortical cells. B: Nodular protrusion of cortical cells still partly covered by attenuated caps... More about this image found in EXTRUSION OF CORTICAL TISSUE THROUGH THE CAPSULE OF NORMAL ADRENAL GLAND A...
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ZONATION OF ADULT ADRENAL <span class="search-highlight">GLAND</span>  An indistinct, discontinuous zona glomerul...
Published: 01 December 2024
ZONATION OF ADULT ADRENAL GLAND Figure 1-29 ZONATION OF ADULT ADRENAL GLAND An indistinct, discontinuous zona glomerulosa beneath the adrenal capsule has a ball-like arrangement of cells, with less abundant lipid-rich cytoplasm than cells of the zona fasciculata. Radial cords of zona fasciculata ... More about this image found in ZONATION OF ADULT ADRENAL GLAND An indistinct, discontinuous zona glomerul...
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ARTIFACTUAL FISSURE FORMATION IN A NORMAL ADRENAL <span class="search-highlight">GLAND</span>  Autolysis at a pla...
Published: 01 December 2024
ARTIFACTUAL FISSURE FORMATION IN A NORMAL ADRENAL GLAND Figure 1-34 ARTIFACTUAL FISSURE FORMATION IN A NORMAL ADRENAL GLAND Autolysis at a plane roughly between cortex and medulla can create the appearance of an empty sac. More about this image found in ARTIFACTUAL FISSURE FORMATION IN A NORMAL ADRENAL GLAND Autolysis at a pla...