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BILATERAL <span class="search-highlight">GIANT</span> ADRENAL MYELOLIPOMAS  The myelolipomas are from an adult ma...
Published: 01 December 2024
BILATERAL GIANT ADRENAL MYELOLIPOMAS Figure 12-1 BILATERAL GIANT ADRENAL MYELOLIPOMAS The myelolipomas are from an adult man with poorly controlled congenital adrenal hyperplasia. The red-brown areas contain hematopoietic cells and blood and the yellow patches consist of fat. Yellow-orange bands ... More about this image found in BILATERAL GIANT ADRENAL MYELOLIPOMAS The myelolipomas are from an adult ma...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-02
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... the adrenal glands are darker than normal. In congenital lipoid adrenal hyperplasia, the accumulation of cholesterol and cholesterol esters may give rise to a nodular cortex which is bright yellow or white. Microscopically, there may be cholesterol clefts with a foreign body giant cell reaction and dystrophic...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-12
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... with thalassemia are reported ( 14 ). Adrenal myelolipomas vary from small lesions discovered incidentally at autopsy to immense masses, the largest to date weighing 11.4 kg ( 22 ). Giant myelolipomas, defined by diameter over 10 cm, are sometimes discovered incidentally but are especially associated...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-08
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... cytoplasmic invaginations ( fig. 8-25 ). Some tumors exhibit significant nuclear pleomorphism ( fig. 8-26 ), forming bizarre giant hyperchromatic nuclei and sometimes multinucleated cells ( figs. 8-27 , 8-28 ). Occasional tumors have prominent mitotic figures ( fig. 8-29 ). PHEOCHROMOCYTOMA Figure 8-20...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-09
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
.... Moslemi   MK , Abolhasani   M , Vafaeimanesh   J . Malignant abdominal paraganglioma presenting as a giant intra-peritoneal mass . Int J Surg Case Rep   2012 ; 3 : 537 - 40 . 74. Linnoila   RI , Keiser   HR , Steinberg   SM , Lack   EE . Histopathology of benign versus...
Images
WARTHIN-FINKELDEY <span class="search-highlight">GIANT</span> CELL  The characteristic <span class="search-highlight">giant</span> cell shows multiple ...
Published: 01 September 2024
WARTHIN-FINKELDEY GIANT CELL Figure 4-29 WARTHIN-FINKELDEY GIANT CELL The characteristic giant cell shows multiple compactly arranged and overlapping pale nuclei. (Courtesy of the CDC IDPB) More about this image found in WARTHIN-FINKELDEY GIANT CELL The characteristic giant cell shows multiple ...
Images
PARAINFLUENZA VIRUS  A: Multinucleated <span class="search-highlight">giant</span> cell formation (due to fusion ...
Published: 01 September 2024
PARAINFLUENZA VIRUS Figure 4-31 PARAINFLUENZA VIRUS A: Multinucleated giant cell formation (due to fusion of infected cells) in lung infection. B: Viral particles were confirmed by appropriate immunohistochemistry. More about this image found in PARAINFLUENZA VIRUS A: Multinucleated giant cell formation (due to fusion ...
Images
CUTANEOUS LEISHMANIASIS  Cutaneous epithelioid cell granulomas have <span class="search-highlight">giant</span> c...
Published: 01 September 2024
CUTANEOUS LEISHMANIASIS Figure 28-6 CUTANEOUS LEISHMANIASIS Cutaneous epithelioid cell granulomas have giant cells and a rim of lymphocytes. Giant cell intracytoplasmic parasites are abundant. (Courtesy of the Armed Forces Institute of Pathology) More about this image found in CUTANEOUS LEISHMANIASIS Cutaneous epithelioid cell granulomas have giant c...
Images
RESPIRATORY SYNCYTIAL VIRUS  Lung shows bronchial mucoid plug formation and...
Published: 01 September 2024
RESPIRATORY SYNCYTIAL VIRUS Figure 4-24 RESPIRATORY SYNCYTIAL VIRUS Lung shows bronchial mucoid plug formation and intra-alveolar hemorrhage (A), with isolated syncytial giant cells visible at medium power (B). Characteristic multinucleated syncytial giant cells are seen at high power, demonstrat... More about this image found in RESPIRATORY SYNCYTIAL VIRUS Lung shows bronchial mucoid plug formation and...
Images
TUBERCULOUS GRANULOMA  Extensive fibrillogranular (caseous) necrosis and su...
Published: 01 September 2024
TUBERCULOUS GRANULOMA Figure 12-53 TUBERCULOUS GRANULOMA Extensive fibrillogranular (caseous) necrosis and surrounding mononuclear inflammatory cell cuff are seen (A,B). Note the isolated peripheral multinucleated giant cells (A). More about this image found in TUBERCULOUS GRANULOMA Extensive fibrillogranular (caseous) necrosis and su...
Images
MEASLES VIRUS  MeV infection of the lung at high power shows a multinucleat...
Published: 01 September 2024
MEASLES VIRUS Figure 4-30 MEASLES VIRUS MeV infection of the lung at high power shows a multinucleated epithelial giant cell with eosinophilic intracytoplasmic and focal intranuclear inclusions. (Courtesy of the CDC IDPB) More about this image found in MEASLES VIRUS MeV infection of the lung at high power shows a multinucleat...
Images
HIV ENCEPHALITIS/ENCEPHALOPATHY  Gliosis and mild lymphocyte infiltration (...
Published: 01 September 2024
HIV ENCEPHALITIS/ENCEPHALOPATHY Figure 3-50 HIV ENCEPHALITIS/ENCEPHALOPATHY Gliosis and mild lymphocyte infiltration (A), multinucleated giant cells (B), and positive immunohistochemistry for p24 antigen (C) are seen. (Courtesy of the CDC IDPB) More about this image found in HIV ENCEPHALITIS/ENCEPHALOPATHY Gliosis and mild lymphocyte infiltration (...
Images
TUBERCULOUS GRANULOMA  Low power shows extensive circumscribed central fibr...
Published: 01 September 2024
TUBERCULOUS GRANULOMA Figure 12-54 TUBERCULOUS GRANULOMA Low power shows extensive circumscribed central fibrillogranular necrosis (A). Some scattered peripheral multinucleated giant cells show a typical Langhans-type morphology (B). More about this image found in TUBERCULOUS GRANULOMA Low power shows extensive circumscribed central fibr...
Images
PULMONARY COCCIDIOIDOMYCOSIS  Confluent well-formed granulomatous foci have...
Published: 01 September 2024
PULMONARY COCCIDIOIDOMYCOSIS Figure 21-8 PULMONARY COCCIDIOIDOMYCOSIS Confluent well-formed granulomatous foci have prominent foreign body-type multinucleated giant cells (A), and prominent necrosis with secondary cavitation (B). (Courtesy of the CDC PHIL) More about this image found in PULMONARY COCCIDIOIDOMYCOSIS Confluent well-formed granulomatous foci have...
Images
LYMPHOGRANULOMA VENEREUM  Low-power appearance of lymph node involvement de...
Published: 01 September 2024
LYMPHOGRANULOMA VENEREUM Figure 18-16 LYMPHOGRANULOMA VENEREUM Low-power appearance of lymph node involvement demonstrates characteristic geographic to stellate necrosis, surrounding palisaded epithelioid cells, and a paucity of multinucleated giant cells. (Courtesy of the AFIP Archives) More about this image found in LYMPHOGRANULOMA VENEREUM Low-power appearance of lymph node involvement de...
Images
BLASTOMYCOSIS  Suppurative granulomas with isolated pale fungal yeasts in t...
Published: 01 September 2024
BLASTOMYCOSIS Figure 21-3 BLASTOMYCOSIS Suppurative granulomas with isolated pale fungal yeasts in the cytoplasm of a giant cell (A), which are often identified due to their weakly birefringent cell wall and central nuclei on a hematoxylin and eosin (H&E) stain (B,C). More about this image found in BLASTOMYCOSIS Suppurative granulomas with isolated pale fungal yeasts in t...
Images
IMMUNE RECONSTITUTION INFLAMMATORY SYNDROME (IRIS), CRYPTOCOCCAL DISEASE  A...
Published: 01 September 2024
IMMUNE RECONSTITUTION INFLAMMATORY SYNDROME (IRIS), CRYPTOCOCCAL DISEASE Figure 9-30 IMMUNE RECONSTITUTION INFLAMMATORY SYNDROME (IRIS), CRYPTOCOCCAL DISEASE A: Cryptococcal CNS IRIS shows granulomatous meningitis with necrosis and giant cells. B: Grocott stain shows damaged fungal yeasts in gra... More about this image found in IMMUNE RECONSTITUTION INFLAMMATORY SYNDROME (IRIS), CRYPTOCOCCAL DISEASE A...
Images
SARS-CoV INFECTION  In the lung, early diffuse alveolar damage (A), multinu...
Published: 01 September 2024
SARS-CoV INFECTION Figure 4-7 SARS-CoV INFECTION In the lung, early diffuse alveolar damage (A), multinucleated syncytial giant cells (B), and the presence of SARS-CoV (red) in pneumocytes and bronchial epithelial cells (C–E) are seen with immunohistochemistry. (Courtesy of the CDC Infectious Dis... More about this image found in SARS-CoV INFECTION In the lung, early diffuse alveolar damage (A), multinu...
Images
PARACOCCIDIOIDOMYCOSIS  A: Well-formed epithelioid cell granulomas with ass...
Published: 01 September 2024
PARACOCCIDIOIDOMYCOSIS Figure 21-17 PARACOCCIDIOIDOMYCOSIS A: Well-formed epithelioid cell granulomas with associated multinucleated giant cells and surrounding lymphocyte infiltrate. (Both: courtesy of G. Varela, Hospital Pablo Tobón Uribe, Medellín, Columbia) B: Weakly refractive round to oval Paracoccidioides yeasts (arrow) can be visualized in the granulomas on a routine H&E stain. More about this image found in PARACOCCIDIOIDOMYCOSIS A: Well-formed epithelioid cell granulomas with ass...