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Images
Published: 01 March 2023
PANCREATIC NEUROENDOCRINE TUMOR Figure 12-53 PANCREATIC NEUROENDOCRINE TUMOR Scattered cells immunolabel for glucagon in this non-functioning PanNET. More about this image found in PANCREATIC NEUROENDOCRINE TUMOR Scattered cells immunolabel for glucagon i...
Images
Published: 01 March 2023
PANCREAS DIVISUM Figure 1-24 PANCREAS DIVISUM Failure of the dorsal and ventral pancreatic buds to fuse leads to a functionally divided pancreas, as seen here, with the larger bile duct (top right) draining into the duodenum separately from the pancreatic ducts (center). More about this image found in PANCREAS DIVISUM Failure of the dorsal and ventral pancreatic buds to fuse...
Book Chapter
Book: Tumors of the Pancreas
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 15
Published: 01 March 2023
DOI:
10.55418/9781933477275-12
ISBN-10: 1-933477-27-X
ISBN: 978-1-933477-27-5
... Scattered cells immunolabel for glucagon in this non-functioning PanNET. PANCREATIC NEUROENDOCRINE TUMOR Figure 12-51 PANCREATIC NEUROENDOCRINE TUMOR Immunolabeling for chromogranin A (left) and synaptophysin (right). PANCREATIC NEUROENDOCRINE TUMOR Figure 12-52 PANCREATIC NEUROENDOCRINE TUMOR...
Book Chapter
Book: Tumors of the Pancreas
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 15
Published: 01 March 2023
DOI:
10.55418/9781933477275-01
ISBN-10: 1-933477-27-X
ISBN: 978-1-933477-27-5
... of an interlobular duct with keratinization. C: Ductal and centroacinar cells with oncocytic metaplasia. D: Ductal cells with goblet cell metaplasia. PANCREAS DIVISUM Figure 1-24 PANCREAS DIVISUM Failure of the dorsal and ventral pancreatic buds to fuse leads to a functionally divided pancreas, as seen here...
Book Chapter
Book: Tumors of the Pancreas
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 15
Published: 01 March 2023
DOI:
10.55418/9781933477275-02
ISBN-10: 1-933477-27-X
ISBN: 978-1-933477-27-5
.... Mixed acinar-ductal carcinoma iii. Mixed acinar-neuroendocrine-ductal carcinoma B. Neuroendocrine neoplasms 1. Neuroendocrine microtumor (<0.5 cm) 2. Pancreatic neuroendocrine tumor (PanNET) a. Nonfunctioning PanNET b. Functioning and hormone-producing PanNETs...
Book Chapter
Book: Tumors of the Pancreas
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 15
Published: 01 March 2023
DOI:
10.55418/9781933477275-15
ISBN-10: 1-933477-27-X
ISBN: 978-1-933477-27-5
... of persistent hyperinsulinemic hypoglycemia of infancy: morphological and molecular studies show structural and functional differences with insulinoma . Diabetes 2003 ; 52 : 784 - 94 . 199. Rahier J , Guiot Y , Sempoux C . Morphologic analysis of focal and diffuse forms of congenital...
Book Chapter
Book: Tumors of the Pancreas
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 15
Published: 01 March 2023
DOI:
10.55418/9781933477275-16
ISBN-10: 1-933477-27-X
ISBN: 978-1-933477-27-5
... typically removed during the procedure and may be attached to the specimen but is often submitted separately. The distal stomach is not resected in a pylorus-preserving pancreatoduodenectomy. This modified procedure leaves the entire stomach and pyloric sphincter intact, providing a better functional...
Book Chapter
Book: Tumors of the Pancreas
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 15
Published: 01 March 2023
DOI:
10.55418/9781933477275-07
ISBN-10: 1-933477-27-X
ISBN: 978-1-933477-27-5
... functional harmonisation of pancreatic cancer subtypes . Gut 2019 ; 68 : 1034 - 43 . 308. Mehta KY , Wu HJ , Menon SS , et al Metabolomic biomarkers of pancreatic cancer: a meta-analysis study . Oncotarget 2017 ; 8 : 68899 - 915 . 309. Bryant KL , Mancias JD...
Book Chapter
Book: Tumors of the Pancreas
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 15
Published: 01 March 2023
DOI:
10.55418/9781933477275-09
ISBN-10: 1-933477-27-X
ISBN: 978-1-933477-27-5
... 1955 ; 141 : 556 - 62 . 6. MacMahon HE , Brown PA , Shen EM . Acinar cell carcinoma of the pancreas with subcutaneous fat necrosis . Gastroenterology 1965 ; 49 : 555 - 9 . 7. Osborne RR . Functioning acinous cell carcinoma of the pancreas accompanied...
Book Chapter
Book: Tumors of the Pancreas
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 15
Published: 01 March 2023
DOI:
10.55418/9781933477275-04
ISBN-10: 1-933477-27-X
ISBN: 978-1-933477-27-5
... gene, whose biallelic inactivation changes the function of the downstream effectors including HIF1α and GLUT-1 (see also General Features). The targeting of VHL in serous cystadenomas contrasts with the genes targeted in the other common pancreatic neoplasms ( 69 ), including pancreatic ductal...
Book Chapter
Book: Tumors of the Pancreas
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 15
Published: 01 March 2023
DOI:
10.55418/9781933477275-11
ISBN-10: 1-933477-27-X
ISBN: 978-1-933477-27-5
... or neprilysin, is a zinc metalloproteinase that functions as part of a regulatory loop to control concentrations of certain peptide substrates and associated peptide-mediated signal transduction ( 146 ). CD10 is broadly expressed in a range of neoplasms and therefore is not diagnostically specific, although...
Book Chapter
Book: Tumors of the Pancreas
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 15
Published: 01 March 2023
DOI:
10.55418/9781933477275-13
ISBN-10: 1-933477-27-X
ISBN: 978-1-933477-27-5
... Hornstein M , Jesinghaus M , et al Pancreatic neuroendocrine tumors with somatostatin expression and paraganglioma-like features . Hum Pathol 2020 ; 102 : 79 - 87 . 165. Zhang L , Liao Q , Hu Y , Zhao Y . Paraganglioma of the pancreas: a potentially functional...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 14
Published: 01 February 2023
DOI:
10.55418/9781933477268-2
ISBN-10: 1-933477-26-1
ISBN: 978-1-933477-26-8
... Classification of Tumours Editorial Board. Female genital tumours, 5th ed. Lyon: IARC; 2020. b HPV = human papillomavirus. Table 2-2 BIOMARKERS COMMONLY USED IN FEMALE LOWER GENITAL TRACT PATHOLOGY Biomarker Function Required Distribution (+) Site Lesion Expected Positive Immunophenotype...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 14
Published: 01 February 2023
DOI:
10.55418/9781933477268-1
ISBN-10: 1-933477-26-1
ISBN: 978-1-933477-26-8
... . 5. Du H , Taylor HS . The role of Hox genes in female reproductive tract development, adult function, and fertility . Cold Spring Harb Perspect Med 2015 ; 6 : a023002 . 6. Herfs M , Yamamoto Y , Laury A , et al A discrete population of squamocolumnar...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 14
Published: 01 February 2023
DOI:
10.55418/9781933477268-4
ISBN-10: 1-933477-26-1
ISBN: 978-1-933477-26-8
... squamous proliferations associated with HPV infection. General Features. The risk factors for vaginal SILs include age at first intercourse and number of sexual partners, as well as conditions that compromise immune function ( 1 ). These factors are similar to those for cervical intraepithelial lesions...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 14
Published: 01 February 2023
DOI:
10.55418/9781933477268-5
ISBN-10: 1-933477-26-1
ISBN: 978-1-933477-26-8
..., for palliative purposes, in patients with lesions not curable by surgery (urethral, anal, or pelvic bone involvement, nonsurgical candidates, recurrences). Prognosis. Survival is a function of tumor stage and lymph node status. About 60 percent of vulvar squamous cell carcinomas are diagnosed at an early stage...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 12
Published: 01 August 2022
DOI:
10.55418/9781933477220-02
ISBN-10: 1-933477-22-9
ISBN: 978-1-933477-22-0
... and vimentin in testes of azoospermic man: an immunohistochemical and morphometric study . Asian J Androl 2002 ; 4 : 55 - 60 . 23. Bustos-Obregon E . Ultrastructure and function of the lamina propria of mammalian seminiferous tubules . Andrologia 1976 ; 8 : 179 - 85 . 24. Bustos...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 13
Published: 01 November 2022
DOI:
10.55418/9781933477251-4
ISBN-10: 1-933477-25-3
ISBN: 978-1-933477-25-1
... and in other endocrine organs, pleomorphism is not related to anaplasia. Examination of the adjacent cortex in nodular hyperplasia shows evidence of hyperplasia, while in nonfunctioning nodules it is normal and in functioning adenomas it is atrophic. Definition. Congenital adrenal hyperplasia (CAH...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 13
Published: 01 November 2022
DOI:
10.55418/9781933477251-3
ISBN-10: 1-933477-25-3
ISBN: 978-1-933477-25-1
... from inflammatory diseases, non-neoplastic enlargements, and neoplasms. The presence of a goiter does not reflect the functional activity of the gland, which can range from euthyroid to hyperthyroid and hypothyroid states. Thyroid hyperplasia often results from disturbances of the feedback system...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 13
Published: 01 November 2022
DOI:
10.55418/9781933477251-1
ISBN-10: 1-933477-25-3
ISBN: 978-1-933477-25-1
... hormone; ADH = antidiuretic hormone. Table 1-3 ANTERIOR PITUITARY HORMONES: CELL TYPE, DISTRIBUTION, AND FUNCTION Cell Type Approximate Cell Percentage in Pituitary Function GH a 40–50% Stimulates linear growth PRL 10–30% Stimulates breast milk production ACTH 10–20...
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