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FIBROCALCIFIC AORTIC VALVE DISEASE  The <span class="search-highlight">functional</span> status of this fibrocalc...
Published: 15 November 2023
FIBROCALCIFIC AORTIC VALVE DISEASE Figure 9-9 FIBROCALCIFIC AORTIC VALVE DISEASE The functional status of this fibrocalcific aortic valve (yellow arrowhead) is inferred by evaluating the left ventricle in explant or autopsy specimens. Concentric hypertrophy (yellow double-headed arrows) indicates... More about this image found in FIBROCALCIFIC AORTIC VALVE DISEASE The functional status of this fibrocalc...
Images
SINGLE <span class="search-highlight">FUNCTIONAL</span> VENTRICLES  Left: Hypoplastic left heart syndrome with ao...
Published: 15 November 2023
SINGLE FUNCTIONAL VENTRICLES Figure 38-1 SINGLE FUNCTIONAL VENTRICLES Left: Hypoplastic left heart syndrome with aortic valve atresia and a hypoplastic but competent mitral valve. The ductal artery (*) is patent. Right: Hypoplastic right heart syndrome with pulmonary valve atresia and a hypoplas... More about this image found in SINGLE FUNCTIONAL VENTRICLES Left: Hypoplastic left heart syndrome with ao...
Images
SINGLE <span class="search-highlight">FUNCTIONAL</span> VENTRICLES: UNIVENTRICULAR ATRIOVENTRICULAR CONNECTIONS  ...
Published: 15 November 2023
SINGLE FUNCTIONAL VENTRICLES: UNIVENTRICULAR ATRIOVENTRICULAR CONNECTIONS Figure 38-2 SINGLE FUNCTIONAL VENTRICLES: UNIVENTRICULAR ATRIOVENTRICULAR CONNECTIONS A: Double inlet ventricle of left ventricular type. B: Single inlet ventricle of left ventricular type (tricuspid atresia). C: Common i... More about this image found in SINGLE FUNCTIONAL VENTRICLES: UNIVENTRICULAR ATRIOVENTRICULAR CONNECTIONS ...
Images
SINGLE <span class="search-highlight">FUNCTIONAL</span> VENTRICLES: FIRST-STAGE PALLIATIVE PROCEDURES  A: Right m...
Published: 15 November 2023
SINGLE FUNCTIONAL VENTRICLES: FIRST-STAGE PALLIATIVE PROCEDURES Figure 38-3 SINGLE FUNCTIONAL VENTRICLES: FIRST-STAGE PALLIATIVE PROCEDURES A: Right modified Blalock-Taussig shunt, for inadequate pulmonary blood flow. B: Pulmonary artery banding, for excessive pulmonary blood flow. C,D: Norwood... More about this image found in SINGLE FUNCTIONAL VENTRICLES: FIRST-STAGE PALLIATIVE PROCEDURES A: Right m...
Images
SINGLE <span class="search-highlight">FUNCTIONAL</span> VENTRICLES: POTENTIAL SECOND-STAGE OPERATIONS  A: Classic...
Published: 15 November 2023
SINGLE FUNCTIONAL VENTRICLES: POTENTIAL SECOND-STAGE OPERATIONS Figure 38-4 SINGLE FUNCTIONAL VENTRICLES: POTENTIAL SECOND-STAGE OPERATIONS A: Classic Glenn operation. B,C: For the following two procedures, bidirectional Glenn (superior cavopulmonary) operation (B) and Hemi-Fontan operation (C),... More about this image found in SINGLE FUNCTIONAL VENTRICLES: POTENTIAL SECOND-STAGE OPERATIONS A: Classic...
Images
SINGLE <span class="search-highlight">FUNCTIONAL</span> VENTRICLES: TWO CURRENT TYPES OF FONTAN OPERATION  Left, ...
Published: 15 November 2023
SINGLE FUNCTIONAL VENTRICLES: TWO CURRENT TYPES OF FONTAN OPERATION Figure 38-5 SINGLE FUNCTIONAL VENTRICLES: TWO CURRENT TYPES OF FONTAN OPERATION Left, right: A bidirectional Glenn-type anastomosis (see fig. 38-4B ) with an extracardiac conduit (left) and with an intra-atrial lateral tunnel (r... More about this image found in SINGLE FUNCTIONAL VENTRICLES: TWO CURRENT TYPES OF FONTAN OPERATION Left, ...
Images
SINGLE <span class="search-highlight">FUNCTIONAL</span> VENTRICLES: TYPES OF FONTAN ANASTOMOSES  The first two ca...
Published: 15 November 2023
SINGLE FUNCTIONAL VENTRICLES: TYPES OF FONTAN ANASTOMOSES Figure 38-6 SINGLE FUNCTIONAL VENTRICLES: TYPES OF FONTAN ANASTOMOSES The first two cases are of historical interest (horizontal sections, viewed from above). A: Atriopulmonary anastomosis. The right atrial appendage is anastomosed direct... More about this image found in SINGLE FUNCTIONAL VENTRICLES: TYPES OF FONTAN ANASTOMOSES The first two ca...
Images
SINGLE <span class="search-highlight">FUNCTIONAL</span> VENTRICLES: CHRONIC PULMONARY CHANGES  A: Following secon...
Published: 15 November 2023
SINGLE FUNCTIONAL VENTRICLES: CHRONIC PULMONARY CHANGES Figure 38-7 SINGLE FUNCTIONAL VENTRICLES: CHRONIC PULMONARY CHANGES A: Following second-stage and third-stage procedures, edema and fibrosis of an interlobular septum occur with numerous dilated lymphatics. Delicate valve (arrow) confirms th... More about this image found in SINGLE FUNCTIONAL VENTRICLES: CHRONIC PULMONARY CHANGES A: Following secon...
Images
EBSTEIN ANOMALY: ABNORMAL ANTERIOR LEAFLET  Left: The <span class="search-highlight">functional</span> orifice is...
Published: 15 November 2023
EBSTEIN ANOMALY: ABNORMAL ANTERIOR LEAFLET Figure 39-7 EBSTEIN ANOMALY: ABNORMAL ANTERIOR LEAFLET Left: The functional orifice is directed toward the outflow tract (*), and the anterior leaflet has numerous fenestrations (yellow arrows) and numerous abnormal cordal attachments to a shelf-like rid... More about this image found in EBSTEIN ANOMALY: ABNORMAL ANTERIOR LEAFLET Left: The functional orifice is...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-11
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
... mutant nevus cell that has acquired a second genetic hit of tumor progression causing the loss of function of PRKAR1A. In this case, the PEM may be part of a combined melanocytic nevus. Other cases have gene fusions involving PRKCA located on chromosome 17 with various partners...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 17
Published: 15 November 2023
10.55418/9781933477299-ch38
ISBN-10: 1-933477-29-6
ISBN: 978-1-933477-29-9
...  Single functional ventricle of right ventricular type  Total anomalous pulmonary venous connection  Heterotaxy syndrome  ECMO a after stage 1 procedure Postoperative  Sinus node dysfunction  Atrial arrhythmias  Cardiac arrest  Pulmonary artery stenosis  Reduced...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-23
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
... burden, which has been linked to a better response to immune checkpoint blockade inhibition. Thus, in the absence of sequence data, assessing the severity of solar elastosis may function as a surrogate for the likelihood of a high mutation burden. Molecular Genetic or Other Parameters There are ongoing...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-05
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
..., if the diagnosis is uncertain, ancillary studies may help, but if the diagnosis remains uncertain in spite of test results, conservative complete excision is a prudent course of action. However, it does not need to be the default option. Considering that surgery can be difficult and functionally or cosmetically...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-13
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
.... Nonsurgical Treatment Options Surgery is not the only treatment option. Comorbidities, related life expectancy, and quality of life issues related to functional and cosmetic concerns may provide a rationale to decline surgery. Consideration may then be given to topical treatment by imiquimod or radiation...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-07
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
... recurrence ( 42 ). Loss of BAP1 is an example of loss of expression or function of a tumor suppressor ( 43 ), but since those lesions are not considered “true” Spitz neoplasms, they are discussed elsewhere. DIAGNOSTIC UTILITY OF GENETIC/GENOMIC ABERRATIONS The detection of a Spitz-associated pathway...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 18
Published: 01 January 2024
10.55418/9781933477367-01
ISBN-10: 1-933477-36-9
ISBN: 978-1-933477-36-7
..., with the axillary lymph nodes receiving over 90 percent of the lymph drained. A small portion of lymph drains into the internal mammary and posterior intercostal lymph nodes. The functional unit of the breast is a complex branching structure arranged into lobes, which in turn are made up of the large duct system...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 18
Published: 01 January 2024
10.55418/9781933477367-04
ISBN-10: 1-933477-36-9
ISBN: 978-1-933477-36-7
...-cadherin and beta catenin showing an absence of expression and p120 catenin showing a cytoplasmic pattern of expression ( fig. 4-19 ). It is more often the variant forms in which aberrant patterns of expression with these antibodies is seen (although this may be a function of bias in the cases selected...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 18
Published: 01 January 2024
10.55418/9781933477367-12
ISBN-10: 1-933477-36-9
ISBN: 978-1-933477-36-7
... rearrangement . Hum Pathol   2015 ; 46 : 1242 - 3 . 25. Pareja   F , Brandes   AH , Basili   T , et al . Loss-of-function mutations in ATP6AP1 and ATP6AP2 in granular cell tumors . Nat Commun   2018 ; 9 : 3533 . 26. Röcken   C , Kronsbein   H , Sletten   K , Roessner...
Images
MITRAL VALVE: SPECIFIC FEATURES  A: Orifice, long-axis view: the anatomic a...
Published: 15 November 2023
MITRAL VALVE: SPECIFIC FEATURES Figure 1-13 MITRAL VALVE: SPECIFIC FEATURES A: Orifice, long-axis view: the anatomic annular orifice (black line) is directed toward the ventricular septum (black arrow). The functional orifice (yellow line), however, is directed toward the ventricular apex (yellow... More about this image found in MITRAL VALVE: SPECIFIC FEATURES A: Orifice, long-axis view: the anatomic a...
Images
EBSTEIN ANOMALY  The septal and posterior tricuspid leaflets are displaced ...
Published: 15 November 2023
EBSTEIN ANOMALY Figure 39-1 EBSTEIN ANOMALY The septal and posterior tricuspid leaflets are displaced downward, the right ventricle is divided into atrialized and functional portions, and the right-sided chambers are dilated. More about this image found in EBSTEIN ANOMALY The septal and posterior tricuspid leaflets are displaced ...