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FABRY DISEASE  Abundant lamellar rings (myelin <span class="search-highlight">figures</span>) are seen within the...
Published: 15 November 2023
FABRY DISEASE Figure 19-20 FABRY DISEASE Abundant lamellar rings (myelin figures) are seen within the myocytes. Similar findings may be seen in hydroxychloroquine cardiotoxicity. More about this image found in FABRY DISEASE Abundant lamellar rings (myelin figures) are seen within the...
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CARDIAC UNDIFFERENTIATED PLEOMORPHIC SARCOMA  Numerous mitotic <span class="search-highlight">figures</span> are ...
Published: 15 November 2023
CARDIAC UNDIFFERENTIATED PLEOMORPHIC SARCOMA Figure 53-7 CARDIAC UNDIFFERENTIATED PLEOMORPHIC SARCOMA Numerous mitotic figures are present, with a brisk acute inflammatory infiltrate in the background. More about this image found in CARDIAC UNDIFFERENTIATED PLEOMORPHIC SARCOMA Numerous mitotic figures are ...
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NEVOID MELANOMA  A: Silhouette of a predominantly intradermal melanocytic p...
Published: 01 February 2024
NEVOID MELANOMA Figure 17-4 NEVOID MELANOMA A: Silhouette of a predominantly intradermal melanocytic proliferation. B: Some of the melanocytes in the dermis are arranged in oddly shaped aggregates. C: The melanocytes display nuclear atypia and mitotic figures. More about this image found in NEVOID MELANOMA A: Silhouette of a predominantly intradermal melanocytic p...
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MELANOCYTIC NEVUS WITH MITOSES  A: Silhouette of a melanocytic nevus that h...
Published: 01 February 2024
MELANOCYTIC NEVUS WITH MITOSES Figure 3-17 MELANOCYTIC NEVUS WITH MITOSES A: Silhouette of a melanocytic nevus that had grown during pregnancy. B: Most of the melanocytes are seen in the dermis, but there is also a junctional proliferation of melanocytes. C: A few mitotic figures are seen (arro... More about this image found in MELANOCYTIC NEVUS WITH MITOSES A: Silhouette of a melanocytic nevus that h...
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NEVOID MELANOMA  A: Plaque-like silhouette of the tumor simulates the appea...
Published: 01 February 2024
NEVOID MELANOMA Figure 17-6 NEVOID MELANOMA A: Plaque-like silhouette of the tumor simulates the appearance of a small congenital nevus. Several thin elongated rete ridges are present. B: The papillary dermis contains dense aggregates of melanocytes, some of which have enlarged nuclei. C: Mitot... More about this image found in NEVOID MELANOMA A: Plaque-like silhouette of the tumor simulates the appea...
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NODULAR NEVOID MELANOMA  A: The tumor has the silhouette of a hypercellular...
Published: 01 February 2024
NODULAR NEVOID MELANOMA Figure 17-7 NODULAR NEVOID MELANOMA A: The tumor has the silhouette of a hypercellular nodule. Several thin, elongated rete ridges are present. B: Analysis of the tumor cells by SNP array revealed chromosomal aberrations, including gain of 6p and losses of 6q and 9p, whic... More about this image found in NODULAR NEVOID MELANOMA A: The tumor has the silhouette of a hypercellular...
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SPITZOID MELANOMA MISDIAGNOSED AS SPITZ NEVUS  A: Symmetric silhouette of a...
Published: 01 February 2024
SPITZOID MELANOMA MISDIAGNOSED AS SPITZ NEVUS Figure 19-2 SPITZOID MELANOMA MISDIAGNOSED AS SPITZ NEVUS A: Symmetric silhouette of a compound pigmented spindle and epithelioid cell neoplasm in a young adult. There are clefts between junctional nests and adjacent hyperplastic epidermis. B: A few ... More about this image found in SPITZOID MELANOMA MISDIAGNOSED AS SPITZ NEVUS A: Symmetric silhouette of a...
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NEVOID MELANOMA  A: Silhouette of a raised papule with smooth surface sugge...
Published: 01 February 2024
NEVOID MELANOMA Figure 17-10 NEVOID MELANOMA A: Silhouette of a raised papule with smooth surface suggesting a possible Miescher nevus. B: The tumor cells are diffusely immunoreactive for PRAME. C: Analysis of the tumor cells by SNP array revealed several copy number changes, including loss of ... More about this image found in NEVOID MELANOMA A: Silhouette of a raised papule with smooth surface sugge...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-03
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
... the rete ridges. The less pigmented areas in between correspond to inter-rete space and dermal papillae where there tends to be less melanin pigment ( 7 ). JUNCTIONAL MELANOCYTIC NEVUS Figure 3-1 JUNCTIONAL MELANOCYTIC NEVUS The macule is circumscribed and light brown. Common Acquired Compound...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-02
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
... (CMN) Figure 2-1 SMALL CONGENITAL MELANOCYTIC NODULE (CMN) A: Well-demarcated brown plaque on the dorsum of the hand of a child. B: The color is uniformly dark brown. The periphery of the lesion is slightly irregular. (Courtesy of Dr. A. Marghoob, New York, NY) A CMN tends to change over time ( 3...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-12
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
... driver mutation: BRAF, especially BRAF V600E a PRAME = preferentially expressed antigen in melanoma; FISH = fluorescence in situ hybridization; CGH/SNP = comparative genomic hybridization/single nucleotide polymorphism. SUPERFICIAL SPREADING MELANOMA Figure 12-1 SUPERFICIAL...
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CMN WITH LYMPHOCYTE-LIKE MELANOCYTES
Published: 01 February 2024
CMN WITH LYMPHOCYTE-LIKE MELANOCYTES Figure 2-8 CMN WITH LYMPHOCYTE-LIKE MELANOCYTES More about this image found in CMN WITH LYMPHOCYTE-LIKE MELANOCYTES
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SPITZOID LENTIGO  The melanocytes associated with this macular hyperpigment...
Published: 01 February 2024
SPITZOID LENTIGO Figure 1-5 SPITZOID LENTIGO The melanocytes associated with this macular hyperpigmentation show large epithelioid features. More about this image found in SPITZOID LENTIGO The melanocytes associated with this macular hyperpigment...