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Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 13
Published: 01 November 2022
DOI: 10.55418/9781933477251-3
ISBN-10: 1-933477-25-3
ISBN: 978-1-933477-25-1
... overlying the second to fourth tracheal rings ( fig. 3-1 ) ( 2 ). Each lobe has a pointed superior pole and a blunt inferior pole. The right lobe may be longer than the left, and the isthmus varies in width between individuals. A pyramidal lobe, which is a vestigial remnant of the thyroglossal duct...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 13
Published: 01 November 2022
DOI: 10.55418/9781933477251-2
ISBN-10: 1-933477-25-3
ISBN: 978-1-933477-25-1
... and adipose tissue. The parenchymal cells are chief cells, oncocytic cells, transitional cells, and clear cells ( fig. 2-1 ). Chief cells measure 8 to 10 µm and are polyhedral, with round central nuclei, eosinophilic to amphophilic cytoplasm, and well-defined cytoplasmic membranes. PARATHYROID GLAND Figure 2...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 13
Published: 01 November 2022
DOI: 10.55418/9781933477251-5
ISBN-10: 1-933477-25-3
ISBN: 978-1-933477-25-1
... in patients with diabetes mellitus and pancreatitis, however, their volume may appear increased (islet cell aggregation) due to a relative decrease in exocrine pancreatic tissue and atrophy ( fig. 5-1 ) ( 132 , 133 ). PANCREATIC ISLET CELL AGGREGATION Figure 5-1 PANCREATIC ISLET CELL AGGREGATION Left: Low...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 13
Published: 01 November 2022
DOI: 10.55418/9781933477251-4
ISBN-10: 1-933477-25-3
ISBN: 978-1-933477-25-1
... infancy. Nodules range in diameter from 60 µm to 400 µm, and may be confused with small neuroblastomas ( 1 , 9 ). Gross Anatomy The adrenal glands are located in the retroperitoneum, superior and slightly anterior and medial to the kidney ( fig. 4-1 ). At birth, the adrenal glands together weigh about 8...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 13
Published: 01 November 2022
DOI: 10.55418/9781933477251-1
ISBN-10: 1-933477-25-3
ISBN: 978-1-933477-25-1
... intermedia, and the pars tuberalis. The pars distalis is the main source of anterior pituitary hormone secretion. A horizontal section of the anterior pituitary reveals fibrous trabeculae in the mid-central portion, with lateral wings and a central mucoid wedge ( fig. 1-1 ). The pars distalis is composed...
Images
SCROTAL FISTULA IN BRUCELLOSIS  (<span class="search-highlight">Fig</span>. 1b from Savasci U, Zor M, Karakas A, ...
Published: 01 August 2022
SCROTAL FISTULA IN BRUCELLOSIS Figure 11-108 SCROTAL FISTULA IN BRUCELLOSIS (Fig. 1b from Savasci U, Zor M, Karakas A, et al. Brucellar epididymo-orchitis: a retrospective multicenter study of 28 cases and review of the literature. Travel Med Infect Dis 2014;12(Pt A):667-72.) More
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TUBERCULOUS EPIDIDYMO-ORCHITIS  Left: The epididymis is extensively involve...
Published: 01 August 2022
TUBERCULOUS EPIDIDYMO-ORCHITIS Figure 11-114 TUBERCULOUS EPIDIDYMO-ORCHITIS Left: The epididymis is extensively involved, with secondary extension into the testis. (Fig. 9.18 from Young RH, Scully RE. Testicular tumors. Chicago: ASCP Press; 1990:207.) Right: Multiple white nodules extensively in... More
Images
MALAKOPLAKIA OF TESTIS  Above: The testis is replaced by a lobulated yellow...
Published: 01 August 2022
MALAKOPLAKIA OF TESTIS Figure 11-117 MALAKOPLAKIA OF TESTIS Above: The testis is replaced by a lobulated yellow mass that simulates a neoplasm. (Fig. 9.25 from Young RH, Scully RE. Testicular tumors. Chicago: ASCP Press; 1990:211.) Right: The testis and epididymis are involved, with tan-gray dis... More
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 12
Published: 01 August 2022
DOI: 10.55418/9781933477220-02
ISBN-10: 1-933477-22-9
ISBN: 978-1-933477-22-0
...EMBRYOLOGY The gonadal anlagen are first evident at 4 to 5 weeks gestational age as paired thickenings of intermediate mesoderm of the dorsal body wall of the embryo along the ventromedial aspect of either mesonephros (the mesonephric ridge) ( fig. 2-1 ). At this early stage of formation...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 12
Published: 01 August 2022
DOI: 10.55418/9781933477220-06
ISBN-10: 1-933477-22-9
ISBN: 978-1-933477-22-0
... ). Rare tumors are familial ( 10 ). Adults, when symptomatic, usually complain of testicular swelling, but gynecomastia causes the patient to seek medical attention in 15 percent of cases ( fig. 6-1 ), and is present in an additional 15 percent on clinical evaluation ( 9 ). Sometimes an impalpable tumor...
Images
EMBRYOLOGY OF TESTIS  Those mesonephric tubules (left) that persist are kno...
Published: 01 August 2022
EMBRYOLOGY OF TESTIS Figure 2-9 EMBRYOLOGY OF TESTIS Those mesonephric tubules (left) that persist are known as the epigenital tubules. They connect with the tubules of the rete testis and become the efferent ductules of the epididymis (right), comprising the head of the epididymis. The remaining... More
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 12
Published: 01 August 2022
DOI: 10.55418/9781933477220-10
ISBN-10: 1-933477-22-9
ISBN: 978-1-933477-22-0
... clinically evident testicular metastases are considered, there is a more balanced representation of tumors from the prostate gland ( figs. 10-1 – 10-7 ), gastrointestinal tract ( fig. 10-8 ) (including appendix), lung ( fig. 10-9 ), kidney ( figs. 10-10 , 10-11 ), urinary bladder ( fig. 10-12...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 12
Published: 01 August 2022
DOI: 10.55418/9781933477220-04
ISBN-10: 1-933477-22-9
ISBN: 978-1-933477-22-0
... generalization but one that has many exceptions, for instance, China, now recognized as a technologically advanced and industrialized country, shows a low incidence of GCNIS-derived tumors ( fig. 4-1 ), likely attributable to genetic factors or for as yet unclear reasons. Overall, the highest rates...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 12
Published: 01 August 2022
DOI: 10.55418/9781933477220-11
ISBN-10: 1-933477-22-9
ISBN: 978-1-933477-22-0
... to chromosomal abnormalities. Gross and Microscopic Findings. Leydig cell hyperplasia is rarely grossly visible but can produce multiple, small, yellow-brown spots or, rarely, larger nodules ( fig. 11-1 ). Microscopic examination shows small aggregates or nodules of Leydig cells ( fig. 11-2 ), usually without...
Images
A PATIENT WITH AN ADULT-TYPE GRANULOSA CELL TUMOR  There is prominent scrot...
Published: 01 August 2022
A PATIENT WITH AN ADULT-TYPE GRANULOSA CELL TUMOR Figure 6-119 A PATIENT WITH AN ADULT-TYPE GRANULOSA CELL TUMOR There is prominent scrotal enlargement and gynecomastia. (figs. 6-119 and 6-120 are from the same patient.) More
Images
EMBRYONAL CARCINOMA  The white areas were firm, and microscopic examination...
Published: 01 August 2022
EMBRYONAL CARCINOMA Figure 4-87 EMBRYONAL CARCINOMA The white areas were firm, and microscopic examination showed prominent fibrosis. (Fig. 3.2 from Young RH, Scully RE. Testicular tumors. Chicago: ASCP Press; 1990;48.) More
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KAPOSIFORM HEMANGIOENDOTHELIOMA  There is a lobular arrangement of solid an...
Published: 01 August 2022
KAPOSIFORM HEMANGIOENDOTHELIOMA Figure 8-83 KAPOSIFORM HEMANGIOENDOTHELIOMA There is a lobular arrangement of solid and glomeruloid vascular structures. (Fig. 4 from Costa FD, Folpe AL. Intratesticular kaposiform haemangioendothelioma in adults: a report of two cases. J Clin Pathol 2013;66:623-6.... More
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SPERM GRANULOMA  A firm, white nodule with foci of necrosis involves the lo...
Published: 01 August 2022
SPERM GRANULOMA Figure 11-83 SPERM GRANULOMA A firm, white nodule with foci of necrosis involves the lower pole of the epididymis. (Fig. 1 from Glassy FJ, Mostofi FK. Spermatic granulomas of the epididymis. Am J Clin Pathol 1956;26:1303-13.) More
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SYPHILITIC GUMMA OF TESTIS  Gummatous necrosis is bordered by a zone of fib...
Published: 01 August 2022
SYPHILITIC GUMMA OF TESTIS Figure 11-116 SYPHILITIC GUMMA OF TESTIS Gummatous necrosis is bordered by a zone of fibrous tissue that contains chronic inflammatory cells. (Fig. 9.21 from Young RH, Scully RE. Testicular tumors. Chicago: ASCP Press; 1990:209.) More
Images
EMBRYOLOGY OF TESTIS  Early in development, the configuration of the gonad ...
Published: 01 August 2022
EMBRYOLOGY OF TESTIS Figure 2-2 EMBRYOLOGY OF TESTIS Early in development, the configuration of the gonad (in red) is elongated between the root of the dorsal mesentery and the mesonephros. (Fig. 16-17 from Sadler TW. Langman’s medical embryology, 12th ed. Philadelphia: Wolters Kluwer; 2011:243.)... More