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Images
in Pheochromocytoma and Adrenal Medullary Hyperplasia
> Tumors of the Adrenal Glands and Extra-Adrenal Paraganglia
Published: 01 December 2024
PHEOCHROMOCYTOMA ASSOCIATED WITH VHL: LIPID DEGENERATION Figure 8-19 PHEOCHROMOCYTOMA ASSOCIATED WITH VHL: LIPID DEGENERATION There is extensive lipid degeneration of the stroma (see gross appearance in fig. 8-12 ). More about this image found in PHEOCHROMOCYTOMA ASSOCIATED WITH VHL: LIPID DEGENERATION There is extensiv...
Images
Published: 01 December 2024
CAROTID BODY PARAGANGLIOMA Figure 9-15 CAROTID BODY PARAGANGLIOMA A: Tumor tissue in most parts of the tumor (same specimen as fig. 9-12 ) shows uniform round nests of weakly eosinophilic cells and cavernous blood vessels. B: This section, taken at the interface between the circumscribed fleshy... More about this image found in CAROTID BODY PARAGANGLIOMA A: Tumor tissue in most parts of the tumor (sam...
Images
Published: 01 December 2024
CAROTID BODY PARAGANGLIOMA Figure 9-15 CAROTID BODY PARAGANGLIOMA A: Tumor tissue in most parts of the tumor (same specimen as fig. 9-12 ) shows uniform round nests of weakly eosinophilic cells and cavernous blood vessels. B: This section, taken at the interface between the circumscribed fleshy... More about this image found in CAROTID BODY PARAGANGLIOMA A: Tumor tissue in most parts of the tumor (sam...
Images
Published: 01 December 2024
PEDIATRIC ADRENAL CORTICAL CARCINOMA Figure 6-44 PEDIATRIC ADRENAL CORTICAL CARCINOMA Synchronous brain metastasis from a malignant pediatric adrenal cortical tumor. (Same case as fig. 6-42 .) More about this image found in PEDIATRIC ADRENAL CORTICAL CARCINOMA Synchronous brain metastasis from a m...
Images
Published: 01 December 2024
NONFUNCTIONAL ADRENAL CORTICAL ADENOMA Figure 5-28 NONFUNCTIONAL ADRENAL CORTICAL ADENOMA Endothelial hyperplasia associated with fibrin (A) and showing mild atypia (B) are present in hemorrhagic areas (same case as fig. 5-27 ). More about this image found in NONFUNCTIONAL ADRENAL CORTICAL ADENOMA Endothelial hyperplasia associated ...
Images
in Pheochromocytoma and Adrenal Medullary Hyperplasia
> Tumors of the Adrenal Glands and Extra-Adrenal Paraganglia
Published: 01 December 2024
PHEOCHROMOCYTOMA: GANGLION CELLS Figure 8-33 PHEOCHROMOCYTOMA: GANGLION CELLS The presence of a few scattered single neurons is a feature of some pheochromocytomas and should not alter the diagnosis; when more conspicuous, they warrant classification as a composite tumor (see fig. 8-53 ). More about this image found in PHEOCHROMOCYTOMA: GANGLION CELLS The presence of a few scattered single ne...
Images
Published: 01 December 2024
ADRENAL CORTICAL ADENOMA ASSOCIATED WITH CUSHING SYNDROME Figure 5-26 ADRENAL CORTICAL ADENOMA ASSOCIATED WITH CUSHING SYNDROME Predominant myelolipomatous changes are present in association with an adenomatous component made of lipid-rich clear cells (same case as fig. 5-16 ). More about this image found in ADRENAL CORTICAL ADENOMA ASSOCIATED WITH CUSHING SYNDROME Predominant myel...
Images
Published: 01 December 2024
PEDIATRIC ADRENAL CORTICAL TUMOR: BENIGN Figure 6-43 PEDIATRIC ADRENAL CORTICAL TUMOR: BENIGN The tumor diffusely expressed SF1 (A). Ki-67 index (B) was 5 percent, whereas p53 was expressed in rare nuclei (C). (Same case as figs. 6-40 and 6-41 .) More about this image found in PEDIATRIC ADRENAL CORTICAL TUMOR: BENIGN The tumor diffusely expressed SF1...
Images
Published: 01 December 2024
PEDIATRIC ADRENAL CORTICAL TUMOR: BENIGN Figure 6-41 PEDIATRIC ADRENAL CORTICAL TUMOR: BENIGN A–C: The tumor is shown at progressively higher magnification. It lacks necrosis and signs of invasion and showed low mitotic and proliferation indexes. Final Wieneke score was 0. (Same case as fig. 6-4... More about this image found in PEDIATRIC ADRENAL CORTICAL TUMOR: BENIGN A–C: The tumor is shown at progre...
Images
Published: 01 December 2024
LYMPH NODE METASTASIS OF ABDOMINAL PARAGANGLIOMA Figure 9-40 LYMPH NODE METASTASIS OF ABDOMINAL PARAGANGLIOMA A: This metastatic tumor could be mistaken for a carcinoma with clear cell features, but was known to correspond to one of the lesions in fig. 9-39 . The diagnosis was confirmed by an im... More about this image found in LYMPH NODE METASTASIS OF ABDOMINAL PARAGANGLIOMA A: This metastatic tumor ...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-01
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... and differentially expressed in a wide variety of tissues. A small amount of testosterone may be produced in the adrenal zona reticularis by 17β-HSD type 5 (also known as aldo-keto reductase family 1 member C3 [AKR1C3]). (Fig. 5 from Asa SL, Uccella S, Tischler A. The unique importance of differentiation...
Images
in Clinicopathologic Features of the Adrenal Cortex
> Tumors of the Adrenal Glands and Extra-Adrenal Paraganglia
Published: 01 December 2024
CUSHING DISEASE Figure 3-8 CUSHING DISEASE Histology of left (upper panels) and right (lower panels) adrenal glands from a patient with a recurrent ACTH-secreting pituitary tumor (same case as fig. 3-3 ). Both glands show a similar morphologic appearance, with a homogeneous increase of cortical ... More about this image found in CUSHING DISEASE Histology of left (upper panels) and right (lower panels) ...
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Published: 01 December 2024
ABDOMINAL PORTION OF THE PREAORTIC SYMPATHETIC TRUNK, WITH THE CELIAC AND HYPOGASTRIC PLEXUSES Figure 9-2 ABDOMINAL PORTION OF THE PREAORTIC SYMPATHETIC TRUNK, WITH THE CELIAC AND HYPOGASTRIC PLEXUSES The major distribution of abdominal paraganglia coincides with the distribution of nerve fibers ... More about this image found in ABDOMINAL PORTION OF THE PREAORTIC SYMPATHETIC TRUNK, WITH THE CELIAC AND H...
Images
Published: 01 December 2024
SPORADIC ADRENAL CORTICAL DISEASE Figure 4-10 SPORADIC ADRENAL CORTICAL DISEASE Nodular enlargement of the adrenal gland (less than 1 cm) with predominant oncocytic features and diffuse and intense Melan-A positivity (C) (same cases as in fig. 4-2 ). Oncocytic features are responsible for the at... More about this image found in SPORADIC ADRENAL CORTICAL DISEASE Nodular enlargement of the adrenal gland...
Images
in Physiology, Development, and Anatomy of the Adrenal Glands
> Tumors of the Adrenal Glands and Extra-Adrenal Paraganglia
Published: 01 December 2024
PRIMORDIA OF ADRENAL GLAND Figure 1-3 PRIMORDIA OF ADRENAL GLAND Schematic cross section of human embryo shows primordia of adrenal glands, which are located lateral to the base of the dorsal mesentery, separated from the gonadal primordium by the adrenal groove. (Fig. 1-3 from Lack EE, Kozakewic... More about this image found in PRIMORDIA OF ADRENAL GLAND Schematic cross section of human embryo shows p...
Images
Published: 01 December 2024
ADRENAL CORTICAL CARCINOMA ARISING IN ADRENAL CORTICAL ADENOMA Figure 6-6 ADRENAL CORTICAL CARCINOMA ARISING IN ADRENAL CORTICAL ADENOMA This adrenal lesion, 11 cm in size (same case as shown in fig. 6-1 ), has two distinct areas: a benign one with <10 HU and the malignant one at 30 HU. (A: C... More about this image found in ADRENAL CORTICAL CARCINOMA ARISING IN ADRENAL CORTICAL ADENOMA This adrena...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-08
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... Anatomic imaging can be performed using computerized tomography (CT) or magnetic resonance imaging (MRI). On CT scan, these tumors are homogeneous with soft tissue density but they may show hemorrhage and necrosis with central low density ( fig. 8-1 ). On MRI they are isointense with liver on T1-weighted...
Images
Published: 01 December 2024
NORMAL CAROTID BODY Figure 9-7 NORMAL CAROTID BODY A: This developing carotid body in an early second trimester stillborn fetus (same case as in figs. 9-3 and 9-4 ), shows more complex architecture and greater admixture of cell types than the abdominal paraganglia. B: Tyrosine hydroxylase exp... More about this image found in NORMAL CAROTID BODY A: This developing carotid body in an early second tri...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 21
Published: 01 December 2024
10.55418/9781933477473-09
ISBN-10: 1-933477-47-4
ISBN: 978-1-933477-47-3
... occasionally in outlier areas. This association was elegantly illustrated by Rex Coupland, the father of modern chromaffin cell biology, in his now classic 1965 book, The Natural History of the Chromaffin Cell ( fig. 9-1 ) ( 9 ). Paragangliomas should, therefore, be considered in the differential...
Images
in Neuroblastoma, Ganglioneuroblastoma, and Ganglioneuroma
> Tumors of the Adrenal Glands and Extra-Adrenal Paraganglia
Published: 01 December 2024
DISTRIBUTION OF NEUROBLASTOMA BY SEX AND STAGE OVER AGE Figure 11-1 DISTRIBUTION OF NEUROBLASTOMA BY SEX AND STAGE OVER AGE Nearly 90 percent of patients are below 5 years of age at diagnosis. The left side of each pair of columns represents male patients and the right side of each pair of column... More about this image found in DISTRIBUTION OF NEUROBLASTOMA BY SEX AND STAGE OVER AGE Nearly 90 percent ...
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