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fibrous
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Images
Published: 01 September 2024
CIRRHOSIS IN CHRONIC HEPATITIS C VIRUS (HCV) INFECTION Figure 5-4 CIRRHOSIS IN CHRONIC HEPATITIS C VIRUS (HCV) INFECTION Multiple fibrous bands and entrapped regenerating liver nodules, some with areas of yellow discoloration as a result of associated fatty change, are seen. More about this image found in CIRRHOSIS IN CHRONIC HEPATITIS C VIRUS (HCV) INFECTION Multiple fibrous ba...
Images
Published: 01 September 2024
CIRRHOSIS DUE TO CHRONIC HEPATITIS B VIRUS (HBV) INFECTION Figure 5-6 CIRRHOSIS DUE TO CHRONIC HEPATITIS B VIRUS (HBV) INFECTION A: Reactive proliferation of cholangioles (ductular reaction). B,C: Progressive entrapment of regenerating hepatic nodules by fibrous septa. D,E: The severely distort... More about this image found in CIRRHOSIS DUE TO CHRONIC HEPATITIS B VIRUS (HBV) INFECTION A: Reactive pro...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-05
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
.... Chronic viral hepatitis is characterized by chronic inflammation, hepatocellular injury, regeneration, and progressive fibrosis. Macroscopically, progressive fibrosis manifests as firm gray-white, irregularly expanded portal regions, and later, fibrous bands. End-stage disease reveals a shrunken...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-28
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... occurs in chronic visceral disease and the spleen typically has a mass of over 1,000 g, with prominent of red pulp expansion. There may also be capsular thickening, splenic infarction, and overlying fibrous adhesion. The enlarged liver typically shows marked Kupffer cell hyperplasia, the latter cells...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-18
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... is sometimes seen, and similar changes occur in the endocervix, endometrium, and fallopian tubes. As the inflammation subsides, there is fibrosis and scarring, leading to fibrous adhesions between luminal and serosal surfaces. In trachoma, a macroscopic pathognomonic feature is the presence of Herbert pits...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 20
Published: 01 September 2024
10.55418/9781933477435-21
ISBN-10: 1-933477-43-1
ISBN: 978-1-933477-43-5
... demonstrate infiltrative, tumor-like masses that can be confused with a neoplasm. Microscopically, these masses are composed predominantly of a prominent fibrous stroma with granulomatous inflammation and an intense eosinophil infiltrate ( fig. 21-43 ). The fungal morphology is similar to that of mucormycosis...
Images
Published: 01 February 2024
MELANOMA ASSOCIATED WITH A CELLULAR BLUE NEVUS Figure 18-6 MELANOMA ASSOCIATED WITH A CELLULAR BLUE NEVUS A: There is an expansile nodule composed of compact spindle cells with no intervening fibrous stroma. It is (on one side) surrounded by cellular areas with aggregates of melanocytes separated... More about this image found in MELANOMA ASSOCIATED WITH A CELLULAR BLUE NEVUS A: There is an expansile no...
Images
Published: 01 February 2024
SCLEROSING BLUE NEVUS Figure 8-7 SCLEROSING BLUE NEVUS A: Much of the superficial portion of the tumor is paucicellular, with abundant fibrous stroma and little melanin pigment deposition. Its deep portion contains more heavily pigmented and denser aggregates of melanocytes. B: Paucimelanotic sp... More about this image found in SCLEROSING BLUE NEVUS A: Much of the superficial portion of the tumor is p...
Images
Published: 01 February 2024
DESMOPLASTIC MELANOMA Figure 16-1 DESMOPLASTIC MELANOMA A: A large pink fibrotic area is seen in the dermis and subcutis. B: The adjacent and overlying epidermis is involved by melanoma in situ. Amelanotic fusiform melanocytes are dispersed in a fibrous matrix. More about this image found in DESMOPLASTIC MELANOMA A: A large pink fibrotic area is seen in the dermis ...
Images
Published: 01 February 2024
MATURATION OF A CMN Figure 2-7 MATURATION OF A CMN Epithelioid melanocytes, some of them pigmented, are arranged in nests in the superficial dermis. With descent into the mid and deep dermis, melanocytes become smaller and splay into fibrous stroma as solitary units. More about this image found in MATURATION OF A CMN Epithelioid melanocytes, some of them pigmented, are a...
Images
Published: 01 February 2024
PURE DESMOPLASTIC MELANOMA Figure 16-5 PURE DESMOPLASTIC MELANOMA A: A diffusely infiltrative fibrosing tumor has lymphocytic aggregates. B: Isolated hyperchromatic spindle cells are dispersed in a fibrous stroma. No dense cellular aggregates are present. More about this image found in PURE DESMOPLASTIC MELANOMA A: A diffusely infiltrative fibrosing tumor has...
Images
Published: 01 February 2024
MIXED DESMOPLASTIC MELANOMA Figure 16-7 MIXED DESMOPLASTIC MELANOMA A densely cellular nodule of tumor cells without intervening fibrous stroma is juxtaposed to a fibrosing tumor cell component of lower cell density, typical of desmoplastic melanoma. More about this image found in MIXED DESMOPLASTIC MELANOMA A densely cellular nodule of tumor cells witho...
Images
Published: 01 February 2024
CELLULAR BLUE NEVUS WITH CYSTIC DEGENERATION Figure 8-16 CELLULAR BLUE NEVUS WITH CYSTIC DEGENERATION Nodule of melanocytes has a peripheral rim of fibrous stroma and central loose edematous stroma and hemorrhage. Some of the vessels have a hyalinized rim. More about this image found in CELLULAR BLUE NEVUS WITH CYSTIC DEGENERATION Nodule of melanocytes has a p...
Images
Published: 01 February 2024
DESMOPLASTIC SPITZ NEVUS Figure 7-16 DESMOPLASTIC SPITZ NEVUS A: The lesion displays a superficial plaque-like silhouette of dense fibrous stroma. B: The dermis is fibrotic and paucicellular. C: Amelanotic spindle and epithelioid melanocytes are present in the dermis in association with ectatic... More about this image found in DESMOPLASTIC SPITZ NEVUS A: The lesion displays a superficial plaque-like ...
Images
Published: 01 February 2024
INTRADERMAL CMN Figure 2-4 INTRADERMAL CMN Melanocytes involve the entire dermis and extend into the superficial subcutis. They show features of maturation. Pigmented epithelioid melanocytes arranged in nests are present superficially, while in the deep dermis and superficial subcutis, amelanotic... More about this image found in INTRADERMAL CMN Melanocytes involve the entire dermis and extend into the ...
Images
Published: 01 February 2024
CELLULAR BLUE NEVUS Figure 8-14 CELLULAR BLUE NEVUS A: Biphasic tumor with background fibrosis and areas of high and low cell density. B: Dense aggregates of cytologically bland melanocytes with elongated nuclei and pale cytoplasm, with admixed melanophages and adjacent pigmented spindle cells i... More about this image found in CELLULAR BLUE NEVUS A: Biphasic tumor with background fibrosis and areas o...
Images
Published: 01 February 2024
ATYPICAL CELLULAR BLUE NEVUS Figure 8-21 ATYPICAL CELLULAR BLUE NEVUS A: Large biphasic cellular BN. B: A part of the lesion is less cellular and composed of bland spindle cells. C: Most of the tumor is composed of a densely cellular sheet-like arrangement of melanocytes with little intervening... More about this image found in ATYPICAL CELLULAR BLUE NEVUS A: Large biphasic cellular BN. B: A part of ...
Images
Published: 01 February 2024
CMN WITH PIGMENTED EPITHELIOCYTOMA/EPITHELIOID BLUE NEVUS-LIKE PN Figure 2-18 CMN WITH PIGMENTED EPITHELIOCYTOMA/EPITHELIOID BLUE NEVUS-LIKE PN A: Low-power view of a portion of a giant CMN that contains a pigmented nodule. B: The pigmented nodule is composed of large epithelioid melanocytes and... More about this image found in CMN WITH PIGMENTED EPITHELIOCYTOMA/EPITHELIOID BLUE NEVUS-LIKE PN A: Low-p...
Images
Published: 01 February 2024
AMELANOTIC CELLULAR AND SCLEROSING BLUE NEVUS Figure 8-19 AMELANOTIC CELLULAR AND SCLEROSING BLUE NEVUS A: Biphasic nodular lesion including areas of abundant fibrous stroma with only a few tumor cells and areas of high cell density with no or minimal intervening stroma. B: The tumor cells are c... More about this image found in AMELANOTIC CELLULAR AND SCLEROSING BLUE NEVUS A: Biphasic nodular lesion i...
Images
Published: 01 February 2024
CELLULAR BLUE NEVUS Figure 8-15 CELLULAR BLUE NEVUS A: Pigmented tumor with an exophytic surface nodule penetrates into the superficial subcutis. B: Fascicles of spindle and epithelioid cells with delicate cytoplasmic granules are present in a fibrous stroma, admixed with clusters of melanophage... More about this image found in CELLULAR BLUE NEVUS A: Pigmented tumor with an exophytic surface nodule pe...
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