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LENTIGINOUS COMPOUND DYSPLASTIC NEVUS WITH LAMELLAR <span class="search-highlight">FIBROSIS</span>  Thin layers o...
Published: 01 February 2024
LENTIGINOUS COMPOUND DYSPLASTIC NEVUS WITH LAMELLAR FIBROSIS Figure 4-5 LENTIGINOUS COMPOUND DYSPLASTIC NEVUS WITH LAMELLAR FIBROSIS Thin layers of fibrosis surround rete ridges, creating a zone separating junctional from dermal melanocytes. There is associated bland-like inflammation. More about this image found in LENTIGINOUS COMPOUND DYSPLASTIC NEVUS WITH LAMELLAR FIBROSIS Thin layers o...
Images
CELLULAR BLUE NEVUS  A: Biphasic tumor with background <span class="search-highlight">fibrosis</span> and areas o...
Published: 01 February 2024
CELLULAR BLUE NEVUS Figure 8-14 CELLULAR BLUE NEVUS A: Biphasic tumor with background fibrosis and areas of high and low cell density. B: Dense aggregates of cytologically bland melanocytes with elongated nuclei and pale cytoplasm, with admixed melanophages and adjacent pigmented spindle cells i... More about this image found in CELLULAR BLUE NEVUS A: Biphasic tumor with background fibrosis and areas o...
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NONSURGICALLY TRAUMATIZED MELANOCYTIC NEVUS (NO RECOLLECTION OR DOCUMENTATI...
Published: 01 February 2024
NONSURGICALLY TRAUMATIZED MELANOCYTIC NEVUS (NO RECOLLECTION OR DOCUMENTATION OF PRIOR BIOPSY) Figure 6-8 NONSURGICALLY TRAUMATIZED MELANOCYTIC NEVUS (NO RECOLLECTION OR DOCUMENTATION OF PRIOR BIOPSY) A: A compound melanocytic nevus with a trizonal pattern is characterized by architectural disord... More about this image found in NONSURGICALLY TRAUMATIZED MELANOCYTIC NEVUS (NO RECOLLECTION OR DOCUMENTATI...
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COMMON BLUE NEVUS  Common blue nevus (BN), uniformly pigmented, extends thr...
Published: 01 February 2024
COMMON BLUE NEVUS Figure 8-5 COMMON BLUE NEVUS Common blue nevus (BN), uniformly pigmented, extends through the entire dermis into the superficial subcutis. There is associated mild stromal fibrosis. More about this image found in COMMON BLUE NEVUS Common blue nevus (BN), uniformly pigmented, extends thr...
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FLEXURAL SITE NEVUS  This compound nevus has junctional nests that vary in ...
Published: 01 February 2024
FLEXURAL SITE NEVUS Figure 5-13 FLEXURAL SITE NEVUS This compound nevus has junctional nests that vary in size and shape. Many nests show cell dyscohesion of melanocytes. The intradermal melanocytes are associated with stromal fibrosis. More about this image found in FLEXURAL SITE NEVUS This compound nevus has junctional nests that vary in ...
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SCALP NEVUS  A: The compound nevus displays plaque-like growth and has a ju...
Published: 01 February 2024
SCALP NEVUS Figure 5-9 SCALP NEVUS A: The compound nevus displays plaque-like growth and has a junctional shoulder. B: It contains areas displaying features of a dysplastic nevus with fusion of nests, random atypia, and stromal fibrosis. More about this image found in SCALP NEVUS A: The compound nevus displays plaque-like growth and has a ju...
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NODULAR MELANOMA ASSOCIATED WITH FEATURES OF REGRESSION  An intradermal den...
Published: 01 February 2024
NODULAR MELANOMA ASSOCIATED WITH FEATURES OF REGRESSION Figure 15-8 NODULAR MELANOMA ASSOCIATED WITH FEATURES OF REGRESSION An intradermal densely cellular nodule of melanoma is present. The adjacent dermis shows features suggesting regression (hypervascularity, fibrosis, lymphocytes, melanophage... More about this image found in NODULAR MELANOMA ASSOCIATED WITH FEATURES OF REGRESSION An intradermal den...
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COMPOUND DYSPLASTIC NEVUS  Melanocyte nests vary in size and shape, and the...
Published: 01 February 2024
COMPOUND DYSPLASTIC NEVUS Figure 4-8 COMPOUND DYSPLASTIC NEVUS Melanocyte nests vary in size and shape, and there is a lentiginous proliferation of solitary units of melanocytes. Some junctional melanocytes show slight nuclear enlargement and hyperchromatism. Mild lamellar fibrosis is present (ar... More about this image found in COMPOUND DYSPLASTIC NEVUS Melanocyte nests vary in size and shape, and the...
Images
VULVAR NEVUS  A: Compound nevus with nests at the dermoepidermal junction t...
Published: 01 February 2024
VULVAR NEVUS Figure 5-5 VULVAR NEVUS A: Compound nevus with nests at the dermoepidermal junction that vary in size and shape and are focally confluent. There is a mixed population of melanocytes in the dermis composed of larger (*) and smaller cells (arrow). B: There are areas of stromal fibrosi... More about this image found in VULVAR NEVUS A: Compound nevus with nests at the dermoepidermal junction t...
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SUPERFICIAL SPREADING MELANOMA WITH SINGLE CELL INVASION  A: The melanocyti...
Published: 01 February 2024
SUPERFICIAL SPREADING MELANOMA WITH SINGLE CELL INVASION Figure 12-14 SUPERFICIAL SPREADING MELANOMA WITH SINGLE CELL INVASION A: The melanocytic neoplasm is asymmetric. Its intraepidermal tumor cell population is predominantly composed of junctional nests. B: The invasive tumor cell lacks compa... More about this image found in SUPERFICIAL SPREADING MELANOMA WITH SINGLE CELL INVASION A: The melanocyti...
Images
UMBILICAL NEVUS  A: Small pigmented macule in the skin of the umbilicus.  B...
Published: 01 February 2024
UMBILICAL NEVUS Figure 5-12 UMBILICAL NEVUS A: Small pigmented macule in the skin of the umbilicus. B: The macule is within a skin fold. C: The histopathology shows a heavily pigmented lentiginous compound nevus. D: Melanocytes are predominantly displayed as solitary units along elongated and ... More about this image found in UMBILICAL NEVUS A: Small pigmented macule in the skin of the umbilicus. B...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-05
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
... atypical nevi, there is focal pagetosis and/or adnexal extension of junctional melanocytes. Intradermal melanocytes may be associated with stromal fibrosis and inflammation ( fig. 5-5 ). Cytologic atypia is common. These lesions may show overlap with what has been reported as “dysplastic nevi” at other...
Images
MELANOMA ARISING IN ASSOCIATION WITH A PLAQUE BLUE NEVUS  A: A densely cell...
Published: 01 February 2024
MELANOMA ARISING IN ASSOCIATION WITH A PLAQUE BLUE NEVUS Figure 18-4 MELANOMA ARISING IN ASSOCIATION WITH A PLAQUE BLUE NEVUS A: A densely cellular nodule is present in the subcutis in association with a portion of a broad plaque-type blue nevus. B: Areas highlighted from the benign blue nevus p... More about this image found in MELANOMA ARISING IN ASSOCIATION WITH A PLAQUE BLUE NEVUS A: A densely cell...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-06
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
... fibrosis parallel to the epidermis, with often prominent fibroblasts and vertically oriented vessels. The epidermis may show attenuation of rete ridges, acanthosis, and hyperkeratosis ( 6 ). By contrast, regressing melanoma typically shows epidermal thinning ( 6 ). Below the scar, a nevus remnant may...
Images
CYST WALL  A core needle biopsy specimen of a breast cyst shows <span class="search-highlight">fibrosis</span> of...
Published: 01 January 2024
CYST WALL Figure 2-20 CYST WALL A core needle biopsy specimen of a breast cyst shows fibrosis of the cyst wall and the attenuated epithelial lining, particularly where it runs along the edges of the core biopsy sample. More about this image found in CYST WALL A core needle biopsy specimen of a breast cyst shows fibrosis of...
Images
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-04
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
... COMPOUND DYSPLASTIC NEVUS WITH LAMELLAR FIBROSIS Figure 4-5 LENTIGINOUS COMPOUND DYSPLASTIC NEVUS WITH LAMELLAR FIBROSIS Thin layers of fibrosis surround rete ridges, creating a zone separating junctional from dermal melanocytes. There is associated bland-like inflammation. INFLAMED DYSPLASTIC NEVUS...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-12
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
..., with or without mitoses  Maturation often absent or incomplete, but beware of “pseudomaturation” Often de novo, but approx. one third may be associated with a nevus  Associated stromal changes include variable inflammation and fibrosis (sometimes reflecting partial regression) Immunohistochemical...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-08
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
... are the common BN and cellular BN. The common BN was first described in detail by Tieche in 1906 ( 18 ). Its characteristic histopathologic feature is the presence of dendritic melanocytes. Variations in the extent of associated features (fibrosis, pigmentation, epithelioid cell features) have led...
Book Chapter
Series: Atlases of Tumor and Non-Tumor Pathology, Series 5
Volume: 19
Published: 01 February 2024
10.55418/9781933477428-03
ISBN-10: 1-933477-42-3
ISBN: 978-1-933477-42-8
... ), stromal fibrosis, and inflammation. In some lesions there may be peculiar distinct alterations: some or many melanocytes display lipidized cytoplasm ( fig. 3-14 ) and oncocytic or plasmacytoid changes ( fig. 3-15 ). Plasmacytoid refers to an appearance of melanocytes with the nucleus placed eccentrically...